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https://www.ohsu.edu/advanced-imaging-research-center/about-advanced-imaging-research-center

Provides magnetic resonance instruments including Siemens 3 Tesla Prisma, Siemens Magnetom 7 Tesla, and Bruker 11.75 Tesla to support research investigating normal physiology, brain development and aging, and disease pathophysiology with high performance non invasive imaging capabilities.

Proper citation: OHSU Advanced Imaging Research Center Core Facility (RRID:SCR_009960) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7c83-8c33-fbab-3b8480000000

Core facility that provides the following services: Custom peptide synthesis service. The Biological Chemistry Resource Center (BCRC) at the Department of Chemistry has been established to provide an open access user facility for state-of-art biophysical analytical instrumentation. The goal of the center is not only to provide access to instrumentation, but also supply the graduate student and post-doc user community with a firm understanding of the scientific principles behind the techniques and on-site expertise to ensure successful experimentation. Instrumentation access will be available to the entire University of Pennsylvania research community.

Proper citation: Penn Biological Chemistry Resource Center (RRID:SCR_009999) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012b-3afd-4e95-62b8-f47280000000

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6,2022. Core facility that provides the following services: Monoclonal antibody development. The Oregon Stem Cell Center Monoclonal Antibody Core is focused on developing monoclonal antibodies that aid investigators in the identification and isolation of novel stem and progenitor cell populations. To enable isolation of live stem cells, personnel within the Monoclonal Antibody Core develop monoclonal antibodies directed against cell surface antigens. Personnel within the laboratory are highly skilled in all aspects of monoclonal antibody generation and characterization, and work closely with investigators throughout the entire immunization, fusion, and screening process. The monoclonal antibody core offers a full complement of services related to the development of monoclonal antibodies.

Proper citation: Oregon Stem Cell Center Monoclonal Antibody Core (RRID:SCR_009997) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000141-9868-14b8-91c7-0c6080000000

Core facility that provides the following services: Hydrogel consultation service, ECM-coated acrylamide hydrogels, Hands-on guidance for cell lysis and molecular/cellular analysis, Preparation of acrylamide-based hydrogel training, Second harmonic generation microscopy, Atomic force microscopy. The Biomechanics Core works with ITMAT faculty from Penn, ITMAT partner institutions, and members of the ITMAT Program in Translational Biomechanics. Consultation and initial pilot experiments performed with the Biomechanics Core are free-of-charge to ITMAT faculty from Penn, ITMAT partner institutions, and members of the ITMAT Program in Translational Biomechanics.

Proper citation: Penn BioMechanics Core Facility (RRID:SCR_009998) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012a-865d-c25e-048a-d9aa80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6, 2022. Core facility that provides the following services: Consultation on protocol development and design process, Exercise testing service, Dual energy x-ray absorptiometry service. The Bionutrition Unit provides nutrition, body composition, and energy expenditure services. Bionutritionist and research kitchen staff are highly experienced and trained to assist investigators with the design and implementation of research meals, feeding studies, and related research. The Bionutrition Unit also provides a variety of energy expenditure and body composition measurement services using a range of equipment.

Proper citation: Oregon Clinical and Translational Research Institute Bionutrition Unit (RRID:SCR_009995) Copy   

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https://www.ohsu.edu/octri/clinical-and-translational-research-center

Provides nursing, bionutrition, study coordination, and laboratory services and support. Laboratory is designed and equipped to perform both basic and specialized research assays and sample processing in support of translational research studies and trials. Laboratory staff have extensive experience in performance of wide variety of analytical and genetic based assays and procedures.

Proper citation: OHSU Oregon Clinical and Translational Research Center Core Facility (RRID:SCR_009996) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/proteomics-shared-resource

Core facility that provides the following services: Protein identification and partial sequencing, Determination of whole protein mass, Targeted SRM analysis of known proteins, Protein quantitation assay, Gel electrophoresis. The OHSU Protemics Shared Resource facility was established to make state-of-the-art mass spectrometry based protein analysis analytical capabilities available to the biomedical research community at OHSU.

Proper citation: OHSU Proteomics Shared Resource Core Facility (RRID:SCR_009991) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-bc23-a113-9dbb-bb2180000000

Core facility that provides the following services: 2D-DIGE equipment access, Trypsin digestion, Metabolite profiling by mass spectrometry, Biomarker quantification by mass spectrometry, Proteomics analysis service. The Proteomics Core Facility in the Penn Genomics Institute is a service and collaborative research resource that balances applied proteomics research with the development of new and improved methods for protein identification, characterization, and quantification. The facility encourages collaborations that apply the tools of proteomics to cutting edge biomedical research. The Proteomics Core Facility is a center not only for services but also for basic and collaborative research and development of two-dimensional gel electrophoretic - and mass spectrometric-based techniques. Prospective users are encouraged to make their inquiries either by e-mail (ian@spirit.gcrc.upenn.edu), or stop by our facility on the eighth floor of BRB II/III.

Proper citation: Penn Proteomics and Systems Biology Core (RRID:SCR_010027) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012b-00c9-007b-79a3-373680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: G-banded karyotyping, Sister chromatid exchange service, Fluorescent in situ hybridization, Chromosome breakage and radial formation analysis, Ploidy/Aneuploidy Assessment, Mitotic index service. A fee-for-service cytogentics laboratory available to genetics researchers to assist in development and execution of cytogenetics experiments for research purposes. Through rigorous standardization of protocols and customized experiment development, the OHSU Research Cytogenetics Core Laboratory provides high quality metaphase and interphase cytogenetic data to the OHSU research community. Services are also available to non-profit and commercial investigators located in Oregon and elsewhere.

Proper citation: OHSU Research Cytogenetics Core Laboratory (RRID:SCR_009992) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/idom/drc/cores/ria.html

Core which offers high quality immunoassay services to basic, translational, and clinical investigators performing diabetes and related metabolic disease research. The core also provides consultation and training and education services.

Proper citation: Penn Diabetes Research Center Radioimmunoassay and Biomarkers Core Facility (RRID:SCR_010028) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013f-52ff-7e24-a468-831a80000000

The MR Sub-Core of the SAIF provides the instrumentation and expertise necessary to perform a broad spectrum of magnetic resonance imaging and spectroscopy studies on a wide range of biological samples including small animals (cats, rabbits, rats, mice), tissue specimens, cultured cells and tissue extracts. This facility includes a conveniently located, well equipped surgery room used for preparing the animals for MR exams and a wide assortment of supporting equipment, i.e. anesthesia machines, MR compatible vital signs monitors (SA Instruments), infusion pumps (Harvard), heating pads, etc. A variety of perishable supplies used in animal preparation are provided by the facility.

Proper citation: Penn Small Animal Imaging Facility: MRI/MRS Sub-Core (RRID:SCR_010032) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013f-5317-8a44-a468-831a80000000

Core facility that provides the following services: Optical/bioluminescence in vivo imaging, Small animal bioluminescence/fluorescence imaging support services. The Optical/Bioluminescence Sub-Core of the SAIF provides the capability to perform cellular and molecular non-invasive in-vivo bioluminescence, fluorescence or near-infrared imaging. The instrumentation allows sensitive, non-invasive molecular imaging for a variety of applications including detection and quantification of various bioluminescent or fluorescent reporter-expressing cells or tissues (in culture or in small animals). The facility currently houses a Perkin Elmer IVIS Lumina II, two LI-COR Pearl Impulse Imagers and a Perkin Elmer IVIS Spectrum. The Facility offers assistance with experimental design, regulatory approval, troubleshooting, data management, analysis and display.

Proper citation: Penn Small Animal Imaging Facility: Optical/Bioluminescence Sub-Core (RRID:SCR_010033) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012b-00ce-7b4f-79a3-373680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. The Neuropathology Core of the Layton Center for Aging and Alzheimer?s Disease Center is dedicated to studying, through autopsy, the brains of individuals who have been followed longitudinally in the Oregon Alzheimer?s Disease Center Clinical Core. Requests for tissue from the Oregon Brain Bank should be directed to Dr. Randall Woltjer. Dr. Woltjer will be glad to communicate with investigators regarding their tissue needs and to assist them in identifying suitable materials for their studies. Material Transfer Agreements between the requesting and sending institutions are needed before shipment.

Proper citation: OHSU Neuropathology Core (RRID:SCR_009988) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/medicinal-chemistry-core/nmr

Core facility that provides the following services: NMR instrument training. A facility that uses a state-of-the-art NMR spectrometer to verify or determine the structure of organic molecules. Housed in the Department of Physiology and Pharmacology, it is designed to exploit the power of designed small molecules as probes of protein and cellular function and to provide the foundation for the development of prototypic therapeutic agents.

Proper citation: OHSU Nuclear Magnetic Resonance Core Facility (RRID:SCR_009989) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000013b-95a6-bd56-c825-3bd680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Automated DNA sequencing, Realtime PCR analysis and SNP analysis, Automated DNA and RNA preps using robotics, Lentiviral vector preparation for cDNA and shRNA transduction and infection, Semi-automated large-scale genomic DNA preparations., Freezing, thawing, and amplification of cell lines, Preparation of both routine and exotic cell culture medium. The Molecular and Cellular Biology Core provides services, reagents and training for all aspects of molecular biology and cell culture. Services include DNA sequencing, real-time PCR, genotyping, robotic RNA and DNA purification, monkey-specific cDNAs, and customized media and buffers for cell culture. The core also produces lentiviral vectors for cDNA and shRNA delivery. Core personnel assist researchers in maintaining and storing cell lines. The core makes available state-of-the-art equipment, including a 969capillary DNA sequencer, realtime qRT-PCR platforms, and fluorometers for cell-based kinetic analyses..

Proper citation: OHSU Molecular and Cellular Biology Core Laboratory (RRID:SCR_009986) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012a-24fd-6e5c-d994-629180000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Monoclonal antibody generation, Scaleup production and purification of antibody from existing cell lines. The VGTI Monoclonal Core offers two basic services: the generation of new monoclonal antibodies and the scaleup production and purification of antibody from existing cell lines (a stand -alone phase IV).

Proper citation: OHSU Monoclonal Antibody Core Laboratory (RRID:SCR_009987) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/gtp/vectorcore/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core whose main aim is to provide vector technology for preclinical studies and other basic research applications. Its services include rovision of AAV, adenoviral and lentiviral based vectors, consultation and advice in the design of custom vectors and in vector serotype/pseudotype selection, and design, cloning and production of plasmid DNA for the production of custom vectors.

Proper citation: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Vector Core Facility (RRID:SCR_010038) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000012a-24ff-c95f-d994-629180000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Flow cytometry training service, Cell sorting service, Specialized flow cytometric assays. The mission of the Immunology Support Core (ISC) is to develop and provide a wide range of state-of-the-art services, assays, and training in support of NIH-sponsored immunology research involving nonhuman primates (NHP).

Proper citation: OHSU Immunology Support Core Flow Cytometry Unit (RRID:SCR_009981) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000142-345f-30d3-91c7-0c6080000000

The CTRC Sleep Core provides services in support of clinical sleep research. It is based at two sites: the CHOP Sleep Laboratory, convenient to the CTRC Outpatient Facility on the 7th Floor of Main Hospital and the University of Pennsylvania?s Sleep Laboratory, located on the 11th Floor of the Gates Building which is part of the medical complex of the Hospital of the University of Pennsylvania. The Sleep Core contains a total of six designated research beds, dedicated staff, and state-of-the-art equipment that provides support for a variety of sleep-related research initiatives. Studies performed in the Sleep Core include overnight polysomnography, multiple sleep latency testing, neurobehavioral testing and actigraphy. The Sleep Core��s goals include providing highest-quality sleep studies, extending sleep research to disciplines not traditionally involved in this area, further developing extant multidisciplinary programs, and offering training opportunities for medical students, residents, fellows, and junior faculty in clinical sleep research. The Sleep Core is associated with CHOP?s and UPHS? American Academy of Sleep Medicine-accredited Sleep Center Laboratories. Services for pediatric and adult subjects: * Study Design * Overnight Polysomnography ** Polysomnography Interpretation * Multiple Sleep Latency Testing * Actigraphy * Neurobehavioral testing * Sleep Core Library

Proper citation: Penn/CHOP CTRC Sleep Core (RRID:SCR_010041) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012b-00c0-7187-9e37-5ded80000000

Patient Coordinator Services is responsible for scheduling the subjects for the research-related appointments; her goal is to facilitate the participation of the subjects in the clinical studies in collaboration with the research staff and the investigators.

Proper citation: Puerto Rico Clinical and Translational Research Consortium Patients Coordinator Services (RRID:SCR_010045) Copy   

•   Source: SciCrunch Registry