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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_AT80
Organism: Homo sapiens (Human)
Disease: Oral cavity squamous cell carcinoma
Category: Cancer cell line
Comments: Problematic cell line: Partially contaminated. Some stocks are contaminated by UM-SCC-1 (PubMed=21868764)..
Proper citation: RRID:CVCL_AT80 Copy
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_7732
Organism: Homo sapiens (Human)
Disease: Hypopharyngeal squamous cell carcinoma
Category: Cancer cell line
Comments: Part of: MD Anderson Cell Lines Project., Problematic cell line: Partially contaminated. At least one lab used a stock contaminated by T24 (Cellosaurus=CVCL_0554) (PubMed=29873307)..
Proper citation: RRID:CVCL_7732 Copy
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_1995
Organism: Homo sapiens (Human)
Disease: High grade ovarian serous adenocarcinoma
Category: Cancer cell line
Comments: Problematic cell line: Partially contaminated. Some stocks are contaminated by COLO 704 (Cellosaurus=CVCL_AV69)..
Proper citation: RRID:CVCL_1995 Copy
Partially Contaminated Discontinued
https://web.expasy.org/cellosaurus/CVCL_1185
Organism: Homo sapiens (Human)
Disease: EBV-related Burkitt lymphoma
Category: Cancer cell line
Comments: Population: African; Ugandan., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Partially contaminated. Some stocks (such as IFO50028) were contaminated by Daudi..
Proper citation: RRID:CVCL_1185 Copy
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_1102
Organism: Homo sapiens (Human)
Disease: Gingival squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Japanese., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Partially contaminated. Some stocks of Ca9-22 are contaminated with MSK-922 (PubMed=21868764)..
Proper citation: RRID:CVCL_1102 Copy
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_DN32
Organism: Canis lupus familiaris (Dog)
Disease: Canine melanoma
Category: Cancer cell line
Comments: Part of: FACC canine tumor cell line panel., Problematic cell line: Partially contaminated. Some stocks of this cell line seemed to have been contaminated by a unknown human cell line (PubMed=21908323)..
Proper citation: RRID:CVCL_DN32 Copy
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_0019
Organism: Homo sapiens (Human)
Disease: Neuroblastoma
Category: Cancer cell line
Comments: Virology: Low susceptibility to infection by Zika virus (ZIKV) (PubMed=29468137)., Characteristics: Particularly suitable for research in neurodegenerative diseases due to the fact that it has a specific uptake of norepinephrine (NA), expresses bona fide neurofilament proteins, and shows activity of enzymes involved in catecholaminergic systems (tyrosine and dopamine-beta-hydroxylases) (PubMed=35893584)., Characteristics: There seem to be differences in the retinoic acid (RA)-induced neuronal phenotype of SH-SY5Y cells from ATCC and ECACC. After 5 days of RA treatment, ECACC cells are slightly larger in size and contains significant amount of neuroblastic (N-type) cells and a small fraction of epithelial (S-type) cells (PubMed=18957096)., Characteristics: Neuroblastic type (N-type) (PubMed=15720811)., Population: Caucasian., From: Memorial Sloan Kettering Cancer Center; New York; USA., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 3., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Partially contaminated. Some laboratories that are redistributing this cell line are in fact redistributing a contaminated cell line of mouse origin (PubMed=25182563)..
Proper citation: RRID:CVCL_0019 Copy
Partially Contaminated Discontinued
https://web.expasy.org/cellosaurus/CVCL_2125
Organism: Homo sapiens (Human)
Disease: Childhood T acute lymphoblastic leukemia
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Partially contaminated. The RCB/Riken RCB1982 stock was contaminated and was replaced by RCB4561 which originates from DSMZ ACC-36. On the basis of STR profile, the version at TKG (TKG 0385) seems to be identical or closely related to the RCB1962 contaminated stock..
Proper citation: RRID:CVCL_2125 Copy
Partially Contaminated Discontinued
https://web.expasy.org/cellosaurus/CVCL_9830
Organism: Homo sapiens (Human)
Disease: Bladder carcinoma
Category: Cancer cell line
Comments: Part of: UBC-40 urothelial bladder cancer cell line index., Part of: BLA-40 bladder carcinoma cell line panel., Problematic cell line: Partially contaminated. Some stocks are contaminated by VM-CUB-1 (PubMed=3708594; PubMed=20143388). Although PubMed=26621286 shows it to be different from VM-CUB-1..
Proper citation: RRID:CVCL_9830 Copy
Partially Contaminated Discontinued
https://web.expasy.org/cellosaurus/CVCL_4407
Organism: Mus musculus (Mouse)
Disease: Mouse mesothelioma
Category: Cancer cell line
Comments: Karyotypic information: Hyper-triploid (PubMed=32944078)., Problematic cell line: Partially contaminated. The stock formerly distributed by CBA under the catalog number CBA-0152 was a mixture of at least two different cell lines from different mouse strains..
Proper citation: RRID:CVCL_4407 Copy
Partially Contaminated Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_5239
Organism: Homo sapiens (Human)
Disease: Cutaneous melanoma
Category: Cancer cell line
Comments: Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: Amelogenin., Characteristics: Established from serial passaging of the parent cell line through immune deficient mice and harvesting lung metastasis., Population: Caucasian., Part of: Wistar Institute melanoma cell line collection., Problematic cell line: Partially contaminated. The stock formerly distributed by Coriell (WC00058) contains a significant amount of mouse DNA (DOI=10.4172/1948-5956.1000196). This is not the case of the original Wistar stock which was distributed by Rockland (DOI=10.4172/1948-5956.1000401)..
Proper citation: RRID:CVCL_5239 Copy
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_6570
Organism: Homo sapiens (Human)
Disease: Ovarian adenocarcinoma
Category: Cancer cell line
Comments: Problematic cell line: Partially contaminated. Some stocks are contaminated by MCF-7 (PubMed=22710073; PubMed=25321415)..
Proper citation: RRID:CVCL_6570 Copy
Partially Contaminated Discontinued
https://web.expasy.org/cellosaurus/CVCL_2309
Organism: Homo sapiens (Human)
Disease: Laryngeal squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Partially contaminated. The ICLC stock (now discontinued) was found to be contaminated, probably by U-251MG (Cellosaurus=CVCL_0021)..
Proper citation: RRID:CVCL_2309 Copy
Partially Contaminated Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_3643
Organism: Homo sapiens (Human)
Disease: Methylmalonic aciduria due to methylmalonyl-CoA mutase deficiency
Category: Finite cell line
Comments: Senescence: Senesces at ~40 PDL (ATCC=CCL-124)., Population: Caucasian., Problematic cell line: Partially contaminated. Some stocks were contaminated by pig LLC-PK1 (PubMed=14505435; PubMed=20143388)..
Proper citation: RRID:CVCL_3643 Copy
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_7075
Organism: Homo sapiens (Human)
Disease: Adult acute megakaryoblastic leukemia
Category: Cancer cell line
Comments: Characteristics: CSF2 dependent., Problematic cell line: Partially contaminated. Some stocks were contaminated by HU-3 (PubMed=10516762)..
Proper citation: RRID:CVCL_7075 Copy
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_6985
Organism: Homo sapiens (Human)
Disease: Oropharyngeal squamous cell carcinoma
Category: Cancer cell line
Comments: Problematic cell line: Partially contaminated. Some stocks are contaminated by T404/T406/Tu 1387Tu 158LN/Tu 159/Tu 182/Tu 212/Tu 212LN (PubMed=21868764)..
Proper citation: RRID:CVCL_6985 Copy
Partially Contaminated
https://web.expasy.org/cellosaurus/CVCL_6984
Organism: Homo sapiens (Human)
Disease: Oropharyngeal squamous cell carcinoma
Category: Cancer cell line
Comments: Problematic cell line: Partially contaminated. Some stocks are contaminated by UM-SCC-1 (PubMed=21868764)..
Proper citation: RRID:CVCL_6984 Copy
Partially Contaminated Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_2785
Organism: Homo sapiens (Human)
Disease: Hepatitis C infection
Category: Cancer cell line
Comments: Population: Japanese., Part of: Liver Cancer Model Repository (LIMORE)., Part of: JFCR45 cancer cell line panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Partially contaminated. Some JCRB stocks were found to be from mouse (PubMed=20143388). Stock bought in 2013 was shown to be human by exome sequencing (personal communication of Rebouissou, Sandra)..
Proper citation: RRID:CVCL_2785 Copy
Partially Contaminated Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_A472
Organism: Homo sapiens (Human)
Disease: Lung small cell carcinoma
Category: Cancer cell line
Comments: Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Partially contaminated. Some cultures of NCI-H1339 are contaminated with NCI-H157 or NCI-1264 (PubMed=25877200)..
Proper citation: RRID:CVCL_A472 Copy
Partially Contaminated Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_2632
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Virology: HTLV-1 producing cell line. Expresses Tax. Is permissive for replication of an HIV-1 gp41 mutant lacking the cytoplasmic tail., Characteristics: Was established by co-cultivation of cells from a 50 year old male T-cell leukemia patient with cord leukocytes from a male infant (CelloPub=CLPUB00542)., Population: Japanese., Problematic cell line: Partially contaminated. Two different lots formerly distributed by NIH-ARP; 13 P7 3/9/92 and 150048; were shown not to be authentic MT-4 (PubMed=9261343; PubMed=31554688)..
Proper citation: RRID:CVCL_2632 Copy
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