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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_KW04
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Proper citation: DiscoverX Cat# 96-0036C1, RRID:CVCL_KW04 Copy
https://web.expasy.org/cellosaurus/CVCL_KW10
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Proper citation: DiscoverX Cat# 96-0058C1, RRID:CVCL_KW10 Copy
https://web.expasy.org/cellosaurus/CVCL_KW01
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Proper citation: DiscoverX Cat# 96-0074C1, RRID:CVCL_KW01 Copy
https://web.expasy.org/cellosaurus/CVCL_KW05
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Proper citation: DiscoverX Cat# 96-0038C1, RRID:CVCL_KW05 Copy
https://web.expasy.org/cellosaurus/CVCL_KW02
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Proper citation: DiscoverX Cat# 96-0004C1, RRID:CVCL_KW02 Copy
https://web.expasy.org/cellosaurus/CVCL_KW06
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Characteristics: InCELL Hunter cell lines express a transfected target protein fragment tagged with a beta-galactosidase fragment (enhanced ProLabel=ePL). The technology measures compound binding to an intracellular target by detecting changes in protein stability. The amount of fusion is quantified through the addition of substrate and a second enzyme fragment (Enzyme acceptor=EA).
Proper citation: DiscoverX Cat# 96-0005C1, RRID:CVCL_KW06 Copy
https://web.expasy.org/cellosaurus/CVCL_KW17
Organism: Mesocricetus auratus (Golden hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0908C16, RRID:CVCL_KW17 Copy
https://web.expasy.org/cellosaurus/CVCL_KW76
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0291C2, RRID:CVCL_KW76 Copy
https://web.expasy.org/cellosaurus/CVCL_KW35
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0486C2, RRID:CVCL_KW35 Copy
https://web.expasy.org/cellosaurus/CVCL_KW29
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0488C2, RRID:CVCL_KW29 Copy
https://web.expasy.org/cellosaurus/CVCL_KW70
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0519C2, RRID:CVCL_KW70 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_KW67
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0197C2, RRID:CVCL_KW67 Copy
https://web.expasy.org/cellosaurus/CVCL_KX15
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0300C2, RRID:CVCL_KX15 Copy
https://web.expasy.org/cellosaurus/CVCL_KW84
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0548C2, RRID:CVCL_KW84 Copy
https://web.expasy.org/cellosaurus/CVCL_KW72
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0959C2, RRID:CVCL_KW72 Copy
https://web.expasy.org/cellosaurus/CVCL_KX00
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0593C2, RRID:CVCL_KX00 Copy
https://web.expasy.org/cellosaurus/CVCL_KW64
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0946C2, RRID:CVCL_KW64 Copy
https://web.expasy.org/cellosaurus/CVCL_KW42
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin parental cell lines express a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA). They can be used to introduce a GPCR tagged with another beta-galactosidase fragment (ProLink=PK).
Proper citation: DiscoverX Cat# 93-0521, RRID:CVCL_KW42 Copy
https://web.expasy.org/cellosaurus/CVCL_KX08
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter NHR protein interaction cell lines co-express a NHR tagged with a beta-galactosidase fragment (ProLink=PK) and a receptor co-activator tagged with another fragment (Enzyme Acceptor=EA). Activation of the NHR results in co-activator-EA recruitment thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0443C2, RRID:CVCL_KX08 Copy
https://web.expasy.org/cellosaurus/CVCL_KW88
Organism: Cricetulus griseus (Chinese hamster)
Disease:
Category: Spontaneously immortalized cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal.
Proper citation: DiscoverX Cat# 93-0591C2, RRID:CVCL_KW88 Copy
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