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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_0045
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Biotechnology: Used for the production of the Gamaleya SARS-CoV-2 (COVID-19) vaccine (Trade name: Gam-COVID-Vac; also known as Sputnik V) (DrugBank=DB15848). Cautio., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 3., Group: Vaccine production cell line.
Proper citation: CLS Cat# 300192, RRID:CVCL_0045 Copy
https://web.expasy.org/cellosaurus/CVCL_6552
Organism: Mus musculus (Mouse)
Disease:
Category: Transformed cell line
Comments:
Proper citation: CLS Cat# 305191, RRID:CVCL_6552 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_4U18
Organism: Homo sapiens (Human)
Disease:
Category: Hybrid cell line
Comments: Characteristics: Can differentiate when cultured in mitogen-free medium. The cells may be used to study developmental regulation of cardiomyocytes (Millipore=SCC109)., Characteristics: Hybrid of adult ventricular cardiomiocytes with a SV40 transformed, uridine auxotroph human fibroblast cell line devoid of mitochondrial DNA (PubMed=15913645)., Group: Patented cell line.
Proper citation: CLS Cat# 305215, RRID:CVCL_4U18 Copy
Discontinued Discontinued
https://web.expasy.org/cellosaurus/CVCL_6355
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Characteristics: Transfected with the pVgRXR vector that contains the VgEcR fusion protein under the control of a CMV promoter and RXRA under the control of a RSV promoter as well as BleoR (PubMed=15141036)., Characteristics: Adenovirus 5 E4 34kda protein is expressed under the control of an ecdysone-inducible promoter (PubMed=15141036).
Proper citation: CLS Cat# 305147, RRID:CVCL_6355 Copy
https://web.expasy.org/cellosaurus/CVCL_7239
Organism: Mus musculus (Mouse)
Disease:
Category: Hybridoma
Comments:
Proper citation: CLS Cat# 305002, RRID:CVCL_7239 Copy
https://web.expasy.org/cellosaurus/CVCL_0120
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments:
Proper citation: CLS Cat# 400103, RRID:CVCL_0120 Copy
https://web.expasy.org/cellosaurus/CVCL_0327
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Secretes several liver products including albumin, alpha-fetoprotein, alpha 1-antitrypin and amylase (ECACC=92110305).
Proper citation: CLS Cat# 400474, RRID:CVCL_0327 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0030
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: HeLa is the most frequent contributor to cell lines contamination., Anecdotal: Was flown since the 1960s on at least ten different space missions: Korabl-Sputnik-2, Vostok-1, Vostok-4, Vostok-5 and Vostok-6, Voshkod 1 and Zond-5, Discoverer XVIII, Progress M-35/Mir and Shuttle STS-89., Anecdotal: The HeLa cell line and its story inspired Australian artist Cynthia Verspaget to embark in 2003 on a artistic project 'The Anarchy Cell Line' (TAnCL) where she mixed her blood with HeLa cells. This work later spawned a PhD thesis (CelloPub=CLPUB00376) where among other things she makes the observation that two main taxonomical distinctions present in the zombie, living/dead and human/nonhuman, are also present in the HeLa cell line., Anecdotal: The fascinating story of the HeLa cell line and of Henrietta Lacks from whom these cells originate are described in the book of Rebecca Skloot (CelloPub=CLPUB00377)., Anecdotal: The HeLa cell line which was established in February 1951 is the oldest human immortal cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: HeLa has 5 five HPV18 integration sites: three on normal chromosomes 8 at 8q24 and two on derivative chromosomes, der(5)t(5;22;8)(q11;q11q13;q24) and der(22)t(8;22) (q24;q13)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Space-flown cell line (cellonaut).
Proper citation: CLS Cat# 300194, RRID:CVCL_0030 Copy
https://web.expasy.org/cellosaurus/CVCL_1D56
Organism: Homo sapiens (Human)
Disease:
Category: Somatic stem cell
Comments:
Proper citation: CLS Cat# 300665, RRID:CVCL_1D56 Copy
https://web.expasy.org/cellosaurus/CVCL_5774
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments:
Proper citation: CLS Cat# 400197, RRID:CVCL_5774 Copy
https://web.expasy.org/cellosaurus/CVCL_1D56
Organism: Homo sapiens (Human)
Disease:
Category: Somatic stem cell
Comments:
Proper citation: CLS Cat# 300661, RRID:CVCL_1D56 Copy
https://web.expasy.org/cellosaurus/CVCL_2480
Organism: Homo sapiens (Human)
Disease:
Category: Finite cell line
Comments: Population: African American.
Proper citation: CLS Cat# 300193, RRID:CVCL_2480 Copy
https://web.expasy.org/cellosaurus/CVCL_D221
Organism: Homo sapiens (Human)
Disease: Oral cavity squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: CLS Cat# 300146, RRID:CVCL_D221 Copy
https://web.expasy.org/cellosaurus/CVCL_5776
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments:
Proper citation: CLS Cat# 400195, RRID:CVCL_5776 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0058
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Anecdotal: The 'S' series of HeLa clones was named after Dr. Florence Sabin., Virology: Has at least 4 five HPV18 integration sites in the genome (PubMed=26550473)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: ENCODE project common cell types; tier 2.
Proper citation: CLS Cat# 300384, RRID:CVCL_0058 Copy
https://web.expasy.org/cellosaurus/CVCL_1D54
Organism: Homo sapiens (Human)
Disease:
Category: Somatic stem cell
Comments:
Proper citation: CLS Cat# 300644, RRID:CVCL_1D54 Copy
https://web.expasy.org/cellosaurus/CVCL_1D58
Organism: Homo sapiens (Human)
Disease:
Category: Somatic stem cell
Comments:
Proper citation: CLS Cat# 300685, RRID:CVCL_1D58 Copy
https://web.expasy.org/cellosaurus/CVCL_5768
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments:
Proper citation: CLS Cat# 400203, RRID:CVCL_5768 Copy
Contaminated Discontinued
https://web.expasy.org/cellosaurus/CVCL_1906
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Population: African American., Part of: KuDOS 95 cell line panel., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=20143388). Originally thought to originate from a 56 year old male patient with a laryngeal carcinoma..
Proper citation: CLS Cat# 300397, RRID:CVCL_1906 Copy
https://web.expasy.org/cellosaurus/CVCL_D215
Organism: Homo sapiens (Human)
Disease: Laryngeal squamous cell carcinoma
Category: Cancer cell line
Comments: Population: Caucasian.
Proper citation: CLS Cat# 300134, RRID:CVCL_D215 Copy
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