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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_2065
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: DSMZ Cat# ACC-647, RRID:CVCL_2065 Copy
Misclassified
https://web.expasy.org/cellosaurus/CVCL_2247
Organism: Homo sapiens (Human)
Disease: Adult T lymphoblastic lymphoma
Category: Cancer cell line
Comments: Problematic cell line: Misclassified. Originally thought to be a Hodgkin lymphoma cell line, but seems to be a T lymphoblastic lymphoma (PubMed=29533902)..
Proper citation: DSMZ Cat# ACC-685, RRID:CVCL_2247 Copy
Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0346
Organism: Homo sapiens (Human)
Disease: Neuroblastoma
Category: Cancer cell line
Comments: Characteristics: Neuroblastic type (N-type)., Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-165, RRID:CVCL_0346 Copy
https://web.expasy.org/cellosaurus/CVCL_2070
Organism: Mesocricetus auratus (Golden hamster)
Disease: Hamster kidney tumor
Category: Cancer cell line
Comments:
Proper citation: DSMZ Cat# ACC-445, RRID:CVCL_2070 Copy
https://web.expasy.org/cellosaurus/CVCL_2073
Organism: Mesocricetus auratus (Golden hamster)
Disease: Hamster pancreatic ductal adenocarcinoma
Category: Cancer cell line
Comments:
Proper citation: DSMZ Cat# ACC-293, RRID:CVCL_2073 Copy
https://web.expasy.org/cellosaurus/CVCL_2072
Organism: Mesocricetus auratus (Golden hamster)
Disease: Hamster pancreatic ductal adenocarcinoma
Category: Cancer cell line
Comments:
Proper citation: DSMZ Cat# ACC-314, RRID:CVCL_2072 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_2050
Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Contaminated. Shown to be a U-343MGa derivative (PubMed=22570425). Originally thought to originate from the brain of a 55 year old patient with a mixed astro-oligodendroglioma (grade II/III)..
Proper citation: DSMZ Cat# ACC-408, RRID:CVCL_2050 Copy
https://web.expasy.org/cellosaurus/CVCL_Y437
Organism: Homo sapiens (Human)
Disease: Chronic lymphocytic leukemia
Category: Transformed cell line
Comments:
Proper citation: DSMZ Cat# ACC-763, RRID:CVCL_Y437 Copy
https://web.expasy.org/cellosaurus/CVCL_IV28
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Population: Caucasian; French., From: International Agency of Research on Cancer (IARC); Lyon; France.
Proper citation: DSMZ Cat# ACC-897, RRID:CVCL_IV28 Copy
https://web.expasy.org/cellosaurus/CVCL_0045
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Biotechnology: Used for the production of the Gamaleya SARS-CoV-2 (COVID-19) vaccine (Trade name: Gam-COVID-Vac; also known as Sputnik V) (DrugBank=DB15848). Cautio., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 3., Group: Vaccine production cell line.
Proper citation: DSMZ Cat# ACC-305, RRID:CVCL_0045 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0030
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: HeLa is the most frequent contributor to cell lines contamination., Anecdotal: Was flown since the 1960s on at least ten different space missions: Korabl-Sputnik-2, Vostok-1, Vostok-4, Vostok-5 and Vostok-6, Voshkod 1 and Zond-5, Discoverer XVIII, Progress M-35/Mir and Shuttle STS-89., Anecdotal: The HeLa cell line and its story inspired Australian artist Cynthia Verspaget to embark in 2003 on a artistic project 'The Anarchy Cell Line' (TAnCL) where she mixed her blood with HeLa cells. This work later spawned a PhD thesis (CelloPub=CLPUB00376) where among other things she makes the observation that two main taxonomical distinctions present in the zombie, living/dead and human/nonhuman, are also present in the HeLa cell line., Anecdotal: The fascinating story of the HeLa cell line and of Henrietta Lacks from whom these cells originate are described in the book of Rebecca Skloot (CelloPub=CLPUB00377)., Anecdotal: The HeLa cell line which was established in February 1951 is the oldest human immortal cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: HeLa has 5 five HPV18 integration sites: three on normal chromosomes 8 at 8q24 and two on derivative chromosomes, der(5)t(5;22;8)(q11;q11q13;q24) and der(22)t(8;22) (q24;q13)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Space-flown cell line (cellonaut).
Proper citation: DSMZ Cat# ACC-57, RRID:CVCL_0030 Copy
https://web.expasy.org/cellosaurus/CVCL_1957
Organism: Mus musculus (Mouse)
Disease:
Category: Hybridoma
Comments:
Proper citation: DSMZ Cat# ACC-471, RRID:CVCL_1957 Copy
https://web.expasy.org/cellosaurus/CVCL_1936
Organism: Mus musculus (Mouse)
Disease:
Category: Hybridoma
Comments:
Proper citation: DSMZ Cat# ACC-89, RRID:CVCL_1936 Copy
https://web.expasy.org/cellosaurus/CVCL_XX00
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16., Characteristics: Transfected with the hprtDR-GFP reporter construct that targets the DR-GFP into the hprt locus and includes a dominant selectable puroR marker. The DR-GFP construct which contains a tandem repeat of two inactive genes coding for EGFP. After transfection with an expression vector coding for the I-SceI enzyme, recombination induced by the cleavage of the I-SceI site recreates a functional EGFP.
Proper citation: DSMZ Cat# ACC-844, RRID:CVCL_XX00 Copy
https://web.expasy.org/cellosaurus/CVCL_XX09
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16., Characteristics: Transfected with the hprtDR-GFP reporter construct that targets the DR-GFP into the hprt locus and includes a dominant selectable puroR marker. The DR-GFP construct which contains a tandem repeat of two inactive genes coding for EGFP. After transfection with an expression vector coding for the I-SceI enzyme, recombination induced by the cleavage of the I-SceI site recreates a functional EGFP., Characteristics: The parental XRCC2 KO cell line is functionally reconstituted by retroviral transfection of XRCC2.
Proper citation: DSMZ Cat# ACC-853, RRID:CVCL_XX09 Copy
https://web.expasy.org/cellosaurus/CVCL_XX01
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16., Characteristics: Transfected with the hprtDR-GFP reporter construct that targets the DR-GFP into the hprt locus and includes a dominant selectable puroR marker. The DR-GFP construct which contains a tandem repeat of two inactive genes coding for EGFP. After transfection with an expression vector coding for the I-SceI enzyme, recombination induced by the cleavage of the I-SceI site recreates a functional EGFP.
Proper citation: DSMZ Cat# ACC-845, RRID:CVCL_XX01 Copy
https://web.expasy.org/cellosaurus/CVCL_XX07
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Characteristics: Transfected with the tetracycline transactivator (tTA) protein, a fusion of tetR with the activation domain of HSV-1 VP16., Characteristics: Transfected with the hprtDR-GFP reporter construct that targets the DR-GFP into the hprt locus and includes a dominant selectable puroR marker. The DR-GFP construct which contains a tandem repeat of two inactive genes coding for EGFP. After transfection with an expression vector coding for the I-SceI enzyme, recombination induced by the cleavage of the I-SceI site recreates a functional EGFP., Characteristics: The parental RAD51C KO cell line is functionally reconstituted by retroviral transfection of RAD51C.
Proper citation: DSMZ Cat# ACC-851, RRID:CVCL_XX07 Copy
https://web.expasy.org/cellosaurus/CVCL_A5EH
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: DSMZ Cat# ACC-875, RRID:CVCL_A5EH Copy
https://web.expasy.org/cellosaurus/CVCL_0063
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Virology: Highly susceptible to infection by Zika virus (ZIKV) (PubMed=29468137)., Part of: MD Anderson Cell Lines Project., Part of: ENCODE project common cell types; tier 3.
Proper citation: DSMZ Cat# ACC-635, RRID:CVCL_0063 Copy
https://web.expasy.org/cellosaurus/CVCL_A5EI
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: DSMZ Cat# ACC-876, RRID:CVCL_A5EI Copy
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