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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_1246
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-893, RRID:CVCL_1246 Copy
https://web.expasy.org/cellosaurus/CVCL_1257
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-894, RRID:CVCL_1257 Copy
Contaminated Discontinued Discontinued Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0372
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Part of: KuDOS 95 cell line panel., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=1246601; PubMed=20143388). Originally thought to originate from an epidermal carcinoma of the mouth..
Proper citation: DSMZ Cat# ACC-136, RRID:CVCL_0372 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_2088
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Population: African American., Problematic cell line: Contaminated. Parent cell line (KB) has been shown to be a HeLa derivative..
Proper citation: DSMZ Cat# ACC-158, RRID:CVCL_2088 Copy
Discontinued Possibly Discontinued
https://web.expasy.org/cellosaurus/CVCL_0346
Organism: Homo sapiens (Human)
Disease: Neuroblastoma
Category: Cancer cell line
Comments: Characteristics: Neuroblastic type (N-type)., Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-165, RRID:CVCL_0346 Copy
https://web.expasy.org/cellosaurus/CVCL_M077
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Population: Caucasian.
Proper citation: DSMZ Cat# ACC-895, RRID:CVCL_M077 Copy
https://web.expasy.org/cellosaurus/CVCL_2066
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: DSMZ Cat# ACC-649, RRID:CVCL_2066 Copy
https://web.expasy.org/cellosaurus/CVCL_2065
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments:
Proper citation: DSMZ Cat# ACC-647, RRID:CVCL_2065 Copy
Misclassified
https://web.expasy.org/cellosaurus/CVCL_2247
Organism: Homo sapiens (Human)
Disease: Adult T lymphoblastic lymphoma
Category: Cancer cell line
Comments: Problematic cell line: Misclassified. Originally thought to be a Hodgkin lymphoma cell line, but seems to be a T lymphoblastic lymphoma (PubMed=29533902)..
Proper citation: DSMZ Cat# ACC-685, RRID:CVCL_2247 Copy
https://web.expasy.org/cellosaurus/CVCL_2070
Organism: Mesocricetus auratus (Golden hamster)
Disease: Hamster kidney tumor
Category: Cancer cell line
Comments:
Proper citation: DSMZ Cat# ACC-445, RRID:CVCL_2070 Copy
https://web.expasy.org/cellosaurus/CVCL_2073
Organism: Mesocricetus auratus (Golden hamster)
Disease: Hamster pancreatic ductal adenocarcinoma
Category: Cancer cell line
Comments:
Proper citation: DSMZ Cat# ACC-293, RRID:CVCL_2073 Copy
https://web.expasy.org/cellosaurus/CVCL_2072
Organism: Mesocricetus auratus (Golden hamster)
Disease: Hamster pancreatic ductal adenocarcinoma
Category: Cancer cell line
Comments:
Proper citation: DSMZ Cat# ACC-314, RRID:CVCL_2072 Copy
https://web.expasy.org/cellosaurus/CVCL_0045
Organism: Homo sapiens (Human)
Disease:
Category: Transformed cell line
Comments: Biotechnology: Used for the production of the Gamaleya SARS-CoV-2 (COVID-19) vaccine (Trade name: Gam-COVID-Vac; also known as Sputnik V) (DrugBank=DB15848). Cautio., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: ENCODE project common cell types; tier 3., Group: Vaccine production cell line.
Proper citation: DSMZ Cat# ACC-305, RRID:CVCL_0045 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0030
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Miscellaneous: HeLa is the most frequent contributor to cell lines contamination., Anecdotal: Was flown since the 1960s on at least ten different space missions: Korabl-Sputnik-2, Vostok-1, Vostok-4, Vostok-5 and Vostok-6, Voshkod 1 and Zond-5, Discoverer XVIII, Progress M-35/Mir and Shuttle STS-89., Anecdotal: The HeLa cell line and its story inspired Australian artist Cynthia Verspaget to embark in 2003 on a artistic project 'The Anarchy Cell Line' (TAnCL) where she mixed her blood with HeLa cells. This work later spawned a PhD thesis (CelloPub=CLPUB00376) where among other things she makes the observation that two main taxonomical distinctions present in the zombie, living/dead and human/nonhuman, are also present in the HeLa cell line., Anecdotal: The fascinating story of the HeLa cell line and of Henrietta Lacks from whom these cells originate are described in the book of Rebecca Skloot (CelloPub=CLPUB00377)., Anecdotal: The HeLa cell line which was established in February 1951 is the oldest human immortal cell line., Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Virology: HeLa has 5 five HPV18 integration sites: three on normal chromosomes 8 at 8q24 and two on derivative chromosomes, der(5)t(5;22;8)(q11;q11q13;q24) and der(22)t(8;22) (q24;q13)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: MD Anderson Cell Lines Project., Part of: Human Protein Atlas, Cell Atlas panel., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Group: Space-flown cell line (cellonaut).
Proper citation: DSMZ Cat# ACC-57, RRID:CVCL_0030 Copy
https://web.expasy.org/cellosaurus/CVCL_Y547
Organism: Homo sapiens (Human)
Disease: Chronic lymphocytic leukemia
Category: Transformed cell line
Comments: Characteristics: Genetically heterogeneous, consists of 3 subclones (PubMed=27566572)., Part of: LL-100 blood cancer cell line panel., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-765, RRID:CVCL_Y547 Copy
https://web.expasy.org/cellosaurus/CVCL_0327
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Secretes several liver products including albumin, alpha-fetoprotein, alpha 1-antitrypin and amylase (ECACC=92110305).
Proper citation: DSMZ Cat# ACC-175, RRID:CVCL_0327 Copy
Contaminated
https://web.expasy.org/cellosaurus/CVCL_2050
Organism: Homo sapiens (Human)
Disease: Glioblastoma
Category: Cancer cell line
Comments: Population: Caucasian., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE)., Problematic cell line: Contaminated. Shown to be a U-343MGa derivative (PubMed=22570425). Originally thought to originate from the brain of a 55 year old patient with a mixed astro-oligodendroglioma (grade II/III)..
Proper citation: DSMZ Cat# ACC-408, RRID:CVCL_2050 Copy
https://web.expasy.org/cellosaurus/CVCL_2103
Organism: Rattus norvegicus (Rat)
Disease: Rat hepatocellular carcinoma
Category: Cancer cell line
Comments:
Proper citation: DSMZ Cat# ACC-195, RRID:CVCL_2103 Copy
https://web.expasy.org/cellosaurus/CVCL_M483
Organism: Homo sapiens (Human)
Disease: Plasma cell myeloma
Category: Cancer cell line
Comments: Caution: On the basis of its characteristics it seems that LOPRA-1 from DSMZ correspond to the clone described as LOPRA-1/5 in the original publication (PubMed=3136791)., Characteristics: Produces IgA2 kappa.
Proper citation: DSMZ Cat# ACC-778, RRID:CVCL_M483 Copy
https://web.expasy.org/cellosaurus/CVCL_1873
Organism: Homo sapiens (Human)
Disease: B acute lymphoblastic leukemia
Category: Cancer cell line
Comments: Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: DSMZ Cat# ACC-490, RRID:CVCL_1873 Copy
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