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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
https://web.expasy.org/cellosaurus/CVCL_A1UX
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: RRID:CVCL_A1UX Copy
https://web.expasy.org/cellosaurus/CVCL_XG77
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments:
Proper citation: RRID:CVCL_XG77 Copy
https://web.expasy.org/cellosaurus/CVCL_XG75
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments:
Proper citation: RRID:CVCL_XG75 Copy
https://web.expasy.org/cellosaurus/CVCL_XG72
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments:
Proper citation: RRID:CVCL_XG72 Copy
https://web.expasy.org/cellosaurus/CVCL_XG76
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments:
Proper citation: RRID:CVCL_XG76 Copy
https://web.expasy.org/cellosaurus/CVCL_LA02
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter activated GPCR internalization cell lines co-express an untagged GPCR, a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA) and a second beta-galactosidase fragment (ProLink=PK) localized to the endosomes. Beta-arrestin recruitment is followed by internalization of the GPCR/arrestin-EA complex in PK-tagged endosomes and allowing complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LA02 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ83
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter activated GPCR internalization cell lines co-express an untagged GPCR, a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA) and a second beta-galactosidase fragment (ProLink=PK) localized to the endosomes. Beta-arrestin recruitment is followed by internalization of the GPCR/arrestin-EA complex in PK-tagged endosomes and allowing complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ83 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ72
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ72 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ99
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter degradation cell lines express a target protein tagged with a beta-galactosidase fragment (Enzyme Donor=ED). Pathway activation results in the degradation of the target protein. The degraded protein is detected by adding to the cell lysis buffer another beta-galactosidase fragment (Enzyme Acceptor=EA). Complementation of the ED and EA enzyme fragments result into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ99 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ86
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter activated GPCR internalization cell lines co-express an untagged GPCR, a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA) and a second beta-galactosidase fragment (ProLink=PK) localized to the endosomes. Beta-arrestin recruitment is followed by internalization of the GPCR/arrestin-EA complex in PK-tagged endosomes and allowing complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ86 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ71
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ71 Copy
https://web.expasy.org/cellosaurus/CVCL_LA04
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LA04 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ75
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ75 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ81
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter beta-arrestin parental cell lines express a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA). They can be used to introduce a GPCR tagged with another beta-galactosidase fragment (ProLink=PK)., Population: Caucasian.
Proper citation: RRID:CVCL_KZ81 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ85
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter activated GPCR internalization cell lines co-express an untagged GPCR, a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA) and a second beta-galactosidase fragment (ProLink=PK) localized to the endosomes. Beta-arrestin recruitment is followed by internalization of the GPCR/arrestin-EA complex in PK-tagged endosomes and allowing complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ85 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ89
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter activated GPCR internalization cell lines co-express an untagged GPCR, a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA) and a second beta-galactosidase fragment (ProLink=PK) localized to the endosomes. Beta-arrestin recruitment is followed by internalization of the GPCR/arrestin-EA complex in PK-tagged endosomes and allowing complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ89 Copy
https://web.expasy.org/cellosaurus/CVCL_LA05
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter total GPCR internalization cell lines co-express a tagged with a beta-galactosidase fragment (ProLink=PK) and a second beta-galactosidase fragment (Enzyme Acceptor=EA) localized to the endosomes. Activation of the GPCR-PK induces internalization of the receptor in EA-tagged endosomes and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LA05 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ93
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter beta-arrestin cell lines co-express a GPCR tagged with a beta-galactosidase fragment (ProLink=PK) and a beta-arrestin tagged with another fragment (Enzyme Acceptor=EA). Activation of the GPCR-PK induces beta-arrestin-EA recruitment and complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ93 Copy
https://web.expasy.org/cellosaurus/CVCL_KZ74
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter NHR protein interaction cell lines co-express a NHR tagged with a beta-galactosidase fragment (ProLink=PK) and a receptor co-activator tagged with another fragment (Enzyme Acceptor=EA). Activation of the NHR results in co-activator-EA recruitment thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_KZ74 Copy
https://web.expasy.org/cellosaurus/CVCL_LA09
Organism: Homo sapiens (Human)
Disease: Osteosarcoma
Category: Cancer cell line
Comments: Characteristics: PathHunter activated GPCR internalization cell lines co-express an untagged GPCR, a beta-arrestin tagged with a beta-galactosidase fragment (Enzyme Acceptor=EA) and a second beta-galactosidase fragment (ProLink=PK) localized to the endosomes. Beta-arrestin recruitment is followed by internalization of the GPCR/arrestin-EA complex in PK-tagged endosomes and allowing complementation of the PK and EA enzyme fragments thus resulting into a catalytically active enzyme that generate a chemiluminescent signal., Population: Caucasian.
Proper citation: RRID:CVCL_LA09 Copy
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