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URL: https://www.jax.org/strain/006021
Proper Citation: RRID:IMSR_JAX:006021
Description: Mus musculus with name NOD.Cg-H2-Ab1b-tm1Gru Tg(CD2-CD4.HLA-DQA1.HLA-DQB1)1Ell/EllJ from IMSR.
Species: Mus musculus
Synonyms:
NOD.DQ8/Ab<0>. NOD.Cg-H2-Ab1
Notes: gene symbol note: CD4 molecule|major histocompatibility complex; class II; DQ beta 1|major histocompatibility complex; class II; DQ alpha 1|histocompatibility 2; class II antigen A; beta 1|CD2 molecule|transgene insertion 1; John F Elliott; mutant strain|congenic strain: CD4|HLA-DQB1|HLA-DQA1|H2-Ab1|CD2|Tg(CD2-CD4;HLA-DQA1;HLA-DQB1)1Ell
Affected Gene: CD4 molecule|major histocompatibility complex; class II; DQ beta 1|major histocompatibility complex; class II; DQ alpha 1|histocompatibility 2; class II antigen A; beta 1|CD2 molecule|transgene insertion 1; John F Elliott
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No rating or validation information has been found for NOD.Cg-H2-Ab1b-tm1Gru Tg(CD2-CD4.HLA-DQA1.HLA-DQB1)1Ell/EllJ.
Issue
Warning. Researchers have noted that this genotype does not sufficiently model human type 1 diabetes mellitus.
Source: Integrated Animals
Source Database: JAX Mice and Services
