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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13506738
Proper Citation: RRID:RGD_13506738
Description: Rattus norvegicus with name GK/Par from RGD.
Species: Rattus norvegicus
Notes: The Goto-Kakizaki (GK) rat is a non-obese Wistar substrain which develops Type 2 diabetes mellitus early in life. The model was developed by Goto and Kakizaki at Tohoku University, Sendai, Japan in 1975. The GK line was established by repeated inbreeding from Wistar rats selected at the upper limit of normal distribution for glucose tolerance. Repeated selection of rats with tendency to lowest glucose tolerance resulted in clear-cut glucose intolerance after five generation.In 1988, GK/Par substrain was established in Paris, France by initiating breeding pairs F35 from Japanese colonies .
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
