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Proper Citation: RRID:MGI:3622318
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: male infertility, short stride length, persistence of hyaloid vascular system, abnormal stria vascularis morphology, impaired luteal cell differentiation, cochlear hair cell degeneration, abnormal posture, premature death, female infertility, abnormal digestion, decreased skeletal muscle fiber diameter, abnormal organ of Corti morphology, stria vascularis degeneration, abnormal esophagus morphology, impaired hearing, absent startle reflex, abnormal gait, increased or absent threshold for auditory brainstem response, decreased startle reflex, abnormal astrocyte physiology, abnormal stria vascularis vasculature morphology, ataxia, cerebellum hypoplasia, cochlear outer hair cell degeneration, cochlear inner hair cell degeneration, hemorrhage, abnormal esophageal squamous epithelium morphology, enlarged esophagus, abnormal cerebellar granule layer morphology, abnormal cerebellum morphology, diluted coat color, abnormal retinal vasculature morphology, retinal hemorrhage, failure of embryo implantation, abnormal corpus luteum morphology, impaired luteinization, reproductive system phenotype, abnormal vascular development, decreased circulating progesterone level, absent corpus luteum, hunched posture, weight loss, decreased Purkinje cell number
Affected Gene: Fzd4
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI