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URL: http://www.taconic.com/transgenic-mouse-model/abb-knockouttransgenic-hla-dr4
Proper Citation: RRID:IMSR_TAC:4149
Description: Mus musculus with name B6.129S2-H2-Ab1tm1Gru Tg(HLA-DRA/H2-Ea.HLA-DRB1*0401/H2-Eb)1Kito from IMSR.
Species: Mus musculus
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1; mutant strain|congenic strain: H2-Ab1
Affected Gene: histocompatibility 2; class II antigen A; beta 1
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No rating or validation information has been found for B6.129S2-H2-Ab1tm1Gru Tg(HLA-DRA/H2-Ea.HLA-DRB1*0401/H2-Eb)1Kito.
Issue
Warning. Researchers have noted that this genotype does not sufficiently model human type 1 diabetes mellitus.
Source: Integrated Animals
Source Database: Taconic Biosciences