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URL: https://www.jax.org/strain/035169
Proper Citation: RRID:IMSR_JAX:035169
Description:
Mus musculus with name B6.Cg-Krastm4Tyj Apc
Species: Mus musculus
Synonyms: KPC:APC
Notes: gene symbol note: APC; WNT signaling pathway regulator|Kras proto-oncogene; GTPase|transgene insertion 752; Eric Fearon|caudal type homeobox 2|Cre recombinase and estrogen receptor 1 (human) fusion gene; mutant strain|congenic strain: Apc|Kras|Tg(CDX2-cre/ERT2)752Erf|CDX2|cre/ERT2
Affected Gene: APC; WNT signaling pathway regulator|Kras proto-oncogene; GTPase|transgene insertion 752; Eric Fearon|caudal type homeobox 2|Cre recombinase and estrogen receptor 1 (human) fusion gene
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Issue
Warning. Researchers have noted that this genotype does not sufficiently model human acute myeloid leukemia.
Source: Integrated Animals
Source Database: JAX Mice and Services