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URL: https://www.jax.org/strain/000664
Proper Citation: RRID:IMSR_JAX:000664
Description: Mus musculus with name C57BL/6J from IMSR.
Species: Mus musculus
Synonyms: B6. B6J. Black 6. C57 Black. C57BL/6JAnu
Notes: gene symbol note: nuclear encoded tRNA arginine 5 (anticodon TCT)|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|glucose homeostasis QTL 1|forebrain weight 1|CD5 antigen|forebrain weight 2|glucose homeostasis QTL 3|gamma-aminobutyric acid type A receptor subunit alpha 2|beta-2 microglobulin|nicotinamide nucleotide transhydrogenase|aryl-hydrocarbon receptor|microwave induced increase in complement receptor B cells|arylalkylamine N-acetyltransferase|annexin A6|hemoglobin beta chain complex|MX dynamin-like GTPase 1|cadherin related 23 (otocadherin)|cytochrome c oxidase subunit 7A2 like|latent transforming growth factor beta binding protein 4|NLR family; pyrin domain containing 12|glucose homeostasis QTL 2|purinergic receptor P2X; ligand-gated ion channel; 7; inbred strain: n-TRtct5|Apobec3|Gluchos1|Fbrwt1|Cd5|Fbrwt2|Gluchos3|Gabra2|B2m|Nnt|Ahr|Micrl|Aanat|Anxa6|Hbb|Mx1|Cdh23|Cox7a2l|Ltbp4|Nlrp12|Gluchos2|P2rx7
Affected Gene: nuclear encoded tRNA arginine 5 (anticodon TCT)|apolipoprotein B mRNA editing enzyme; catalytic polypeptide 3|glucose homeostasis QTL 1|forebrain weight 1|CD5 antigen|forebrain weight 2|glucose homeostasis QTL 3|gamma-aminobutyric acid type A receptor subunit alpha 2|beta-2 microglobulin|nicotinamide nucleotide transhydrogenase|aryl-hydrocarbon receptor|microwave induced increase in complement receptor B cells|arylalkylamine N-acetyltransferase|annexin A6|hemoglobin beta chain complex|MX dynamin-like GTPase 1|cadherin related 23 (otocadherin)|cytochrome c oxidase subunit 7A2 like|latent transforming growth factor beta binding protein 4|NLR family; pyrin domain containing 12|glucose homeostasis QTL 2|purinergic receptor P2X; ligand-gated ion channel; 7
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Issue
Warning this mouse may be epileptogenic. The cause seems to be that the GABAA receptor is expressed at very low levels compared to other mouse strains including the C57BL/6N, according to Hawkins (2016) and Mulligan (2019).
Source: Integrated Animals
Source Database: JAX Mice and Services
