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URL: https://www.infrafrontier.eu/emma/strain-details/?q=5303
Proper Citation: RRID:IMSR_EM:05303
Description: Mus musculus with name B6;129S7-Prnptm1Cwe/CweOrl from IMSR.
Species: Mus musculus
Synonyms: Prp-KO
Notes: gene symbol note: prion protein; mutant strain: Prnp
Affected Gene: prion protein
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No rating or validation information has been found for B6;129S7-Prnptm1Cwe/CweOrl.
Issue
Warning. Researchers have noted that this genotype does not sufficiently model human Creutzfeldt-Jakob disease.
Issue
Warning. Researchers have noted that this genotype does not sufficiently model human Gerstmann-Straussler-Scheinker syndrome.
Source: Integrated Animals
Source Database: European Mouse Mutant Archive
