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Cleveland Clinic Lerner Research Institute Center for Therapeutics Discovery Core Facility (RRID:SCR_027386)Copy Citation Copied
URL: https://www.lerner.ccf.org/therapeutics-discovery/
Proper Citation: Cleveland Clinic Lerner Research Institute Center for Therapeutics Discovery Core Facility (RRID:SCR_027386)
Description: Core to promote translation of basic science discoveries by Cleveland Clinic researchers into new therapeutics. Through collaboration with investigators we de-risk promising approaches and illuminate fundamental biology using small molecule chemical probes. We have established a pipeline of innovative research programs directed toward improving patient care with a true bench-to-bedside vision. To achieve these goals, we use state of the art technologies in small molecule library screening, fragment-based methods, X-ray crystallography, computational tools, and target validation towards generating starting points for nascent hit-to-lead and lead optimization campaigns.
Synonyms: , Cleveland Clinic Center for Therapeutics Discovery, Cleveland Clinic Center for Therapeutics Discovery (C3TD)
Resource Type: service resource, access service resource, core facility
Keywords: ABRF, new therapeutics, small molecule library screening, fragment-based methods, X-ray crystallography,
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