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URL: http://www.stanleyresearch.org/dnn/BrainResearchLaboratory/tabid/195/Default.aspx
Proper Citation: Stanley Brain Collection (RRID:SCR_007062)
Description: It is a widely used resource for researchers trying to find the causes of, and better treatments for, schizophrenia, bipolar disorder and major depression. Brains were collected 1994 to 2005 with the permission of the families in a standardized manner, with half of each specimen being frozen and half fixed in formalin. Currently four cohorts are available for study; the Neuropathology Consortium consisting of 60 cases (15 each schizophrenia, bipolar disorder, depression, and controls), the Array Collection consisting of 105 cases (35 each schizophrenia, bipolar disorder, and controls), the Depression Collection consisting of 36 cases (12 each depression with psychosis, depression without psychosis, and controls), and the Parietal Collection of 48 cases (fixed inferior parietal sections from 24 each schizophrenia and controls). Since 1996, the Stanley Brain Collection has sent over 200,000 sections and 10,000 blocks of brain tissue to 240 research laboratories in 23 states and 20 foreign countries. All tissue has been provided to the researchers without charge. All costs for collecting, processing, and storing the brain tissue have been borne by The Stanley Medical Research Institute as a public service. All reasonable requests for brain tissue (over 90 percent of applications) have been honored. Researchers selected to receive tissue must sign an agreement that sets forth conditions for its use. Results received from researchers become part of the Stanley brain collection data set and will be used for integrative, multivariate analyses. In addition to overseeing the brain collection, the laboratory conducts research on the neuropathology of schizophrenia and bipolar disorder and on brain development. Many studies carried out at the Stanley Brain Research Laboratory are done in cooperation with studies at the Stanley Laboratory of Developmental Neurovirology.
Abbreviations: Stanley Brain Collection
Synonyms: Stanley Brain Research Laboratory Brain Collection, Stanley Brain Research Laboratory and Brain Collection
Resource Type: biomaterial supply resource, tissue bank, material resource, brain bank
Defining Citation: PMID:10913747
Keywords: schizophrenia, bipolar disorder, major depressive disorder, depressive disorder, control, normal control, psychotic disorder, neuropathy, post-mortem, array, parietal, brain development, microarray, brain, tissue, brain tissue, frozen, formalin
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