Searching the RRID Resource Information Network
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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BALB/c.129P2-Tlr2tm1Aki/Obs Resource Report Resource Website 1+ mentions Issue |
RRID:IMSR_OBS:9 | Mus musculus |
C.129P2(B6)-Tlr2 |
gene symbol note: toll-like receptor 2; mutant strain|congenic strain: Tlr2 | toll-like receptor 2 | targeted mutation 1; Shizuo Akira | OBS:9 | Oriental BioService, Inc. | OBS | live | 2026-02-14 01:02:37 | 1 | ||||
|
BALB/c-Rag2tm1Fwa Il2rg Resource Report Resource Website Issue Issue |
RRID:IMSR_BRGSF-A2 | Mus musculus |
C.Cg-Rag2 |
gene symbol note: recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin; coisogenic strain|mutant strain: Rag2|Flt3|Il2rg|Sirpa|H2-D|HLA-A2.1|B2m | recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin | targeted mutation 1; Frederick W Alt|targeted mutation 1; Ihor R Lemischka|targeted mutation 1; University of Cologne|unknown|transgene insertion 1; Beatrice Perarnau | BRGSF-A2 | genOway | GENO | live | 2026-02-14 01:02:37 | 0 | ||||
|
B6.MRL-Faslpr/Orl Resource Report Resource Website 1+ mentions Issue |
RRID:IMSR_EM:00037 | Mus musculus |
C57BL/6 - lpr. B6-Tnfrsf6 |
gene symbol note: Fas cell surface death receptor; congenic strain: Fas | Fas cell surface death receptor | lymphoproliferation | EM:00037 | European Mouse Mutant Archive | EMMA | embryo | 2026-02-14 01:02:38 | 2 | ||||
|
B6.129-B2mtm1Unc H2-Ab1 Resource Report Resource Website Issue |
RRID:IMSR_EM:00030 | Mus musculus |
B6.Cg-B2m |
gene symbol note: histocompatibility 2; class II antigen A; beta 1|beta-2 microglobulin; mutant strain: H2-Ab1|B2m | histocompatibility 2; class II antigen A; beta 1|beta-2 microglobulin | targeted mutation 1; Christophe Benoist and Diane Mathis|targeted mutation 1; University of North Carolina | EM:00030 | European Mouse Mutant Archive | EMMA | embryo | 2026-02-14 01:02:38 | 0 | ||||
|
B6;129S7-Prnptm1Cwe Tg(Prnp)e19hCwe/CweCnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:00064 | Mus musculus |
PrPC-KO. E1931. B6;129S7-Prnp |
gene symbol note: transgene insertion e19h; Charles Weissmann|prion protein; mutant strain: Tg(Prnp)e19hCwe|Prnp | transgene insertion e19h; Charles Weissmann|prion protein | transgene insertion e19h; Charles Weissmann|targeted mutation 1; Charles Weissmann | EM:00064 | European Mouse Mutant Archive | EMMA | embryo | 2026-02-14 01:02:38 | 0 | ||||
|
B6;129S7-Prnptm1Cwe Tg(Prnp)d11Cwe/CweCnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:00056 | Mus musculus |
STOCK Prnp |
gene symbol note: transgene insertion d11; Charles Weissmann|prion protein; mutant strain: Tg(Prnp)d11Cwe|Prnp | transgene insertion d11; Charles Weissmann|prion protein | transgene insertion d11; Charles Weissmann|targeted mutation 1; Charles Weissmann | EM:00056 | European Mouse Mutant Archive | EMMA | embryo | 2026-02-14 01:02:38 | 0 | ||||
|
B6;129S7-Prnptm1Cwe Tg(Alb1-Prnp)19Cwe/CweCnrm Resource Report Resource Website 1+ mentions Issue Issue |
RRID:IMSR_EM:00177 | Mus musculus |
B6;129S7 Prnp |
gene symbol note: prion protein|transgene insertion 19; Charles Weissmann; mutant strain: Prnp|Tg(Alb1-Prnp)19Cwe | prion protein|transgene insertion 19; Charles Weissmann | targeted mutation 1; Charles Weissmann|transgene insertion 19; Charles Weissmann | EM:00177 | European Mouse Mutant Archive | EMMA | embryo | 2026-02-14 01:02:40 | 1 | ||||
|
B6;129S7-Prnptm1Cwe Tg(Lck-Prnp)71Cwe/CweCnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:00179 | Mus musculus |
STOCK Prnp |
gene symbol note: transgene insertion 71; Charles Weissmann|prion protein; mutant strain: Tg(Lck-Prnp)71Cwe|Prnp | transgene insertion 71; Charles Weissmann|prion protein | transgene insertion 71; Charles Weissmann|targeted mutation 1; Charles Weissmann | EM:00179 | European Mouse Mutant Archive | EMMA | embryo | 2026-02-14 01:02:40 | 0 | ||||
|
B6;129S7-Prnptm1Cwe Tg(Alb1-Prnp)01Cwe/CweCnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:00176 | Mus musculus |
STOCK Prnp |
gene symbol note: prion protein|transgene insertion 01; Charles Weissmann; mutant strain: Prnp|Tg(Alb1-Prnp)01Cwe | prion protein|transgene insertion 01; Charles Weissmann | targeted mutation 1; Charles Weissmann|transgene insertion 01; Charles Weissmann | EM:00176 | European Mouse Mutant Archive | EMMA | embryo | 2026-02-14 01:02:40 | 0 | ||||
|
B6.129(Cg)-Apoetm1Unc Ighm Resource Report Resource Website Issue Issue Issue |
RRID:IMSR_EM:00394 | Mus musculus |
apolipoprotein E KO and muMT KO. B6.129(Cg)-Apoe |
gene symbol note: immunoglobulin heavy constant mu|apolipoprotein E; mutant strain: Ighm|Apoe | immunoglobulin heavy constant mu|apolipoprotein E | targeted mutation 1; University of Cologne|targeted mutation 1; University of North Carolina | EM:00394 | European Mouse Mutant Archive | EMMA | embryo | 2026-02-14 01:02:41 | 0 | ||||
|
B6.129-Apoetm1Unc Tcrd Resource Report Resource Website Issue |
RRID:IMSR_EM:00395 | Mus musculus | apolipoprotein E KO and TCRdeltaKO | gene symbol note: T cell receptor delta chain|apolipoprotein E; mutant strain: Tcrd|Apoe | T cell receptor delta chain|apolipoprotein E | targeted mutation 1; Peter Mombaerts|targeted mutation 1; University of North Carolina | EM:00395 | European Mouse Mutant Archive | EMMA | embryo | 2026-02-14 01:02:41 | 0 | ||||
|
NOD.129(B6)-B2mtm1Unc H2-Ab1 Resource Report Resource Website Issue |
RRID:IMSR_EM:00213 | Mus musculus |
NOD.129(B6)-B2m |
gene symbol note: beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1; mutant strain: B2m|H2-Ab1 | beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1 | targeted mutation 1; University of North Carolina|targeted mutation 1; Christophe Benoist and Diane Mathis | EM:00213 | European Mouse Mutant Archive | EMMA | embryo | 2026-02-14 01:02:40 | 0 | ||||
|
B6;129S2-Il6tm1Kopf/YiwRbrc Resource Report Resource Website Issue Issue |
RRID:IMSR_RBRC04918 | Mus musculus | gene symbol note: interleukin 6; mutant stock: Il6 | interleukin 6 | targeted mutation 1; Manfred Kopf | RBRC04918 | RIKEN BioResource Research Center | RBRC | embryo | 2026-02-14 12:53:50 | 0 | |||||
|
C;129S2-Il6tm1Kopf/YiwRbrc Resource Report Resource Website Issue Issue |
RRID:IMSR_RBRC04919 | Mus musculus |
C.129S2-Il6 |
gene symbol note: interleukin 6; mutant stock: Il6 | interleukin 6 | targeted mutation 1; Manfred Kopf | RBRC04919 | RIKEN BioResource Research Center | RBRC | sperm | 2026-02-14 12:53:50 | 0 | ||||
|
B6.Cg-Ighmtm1Cgn Tg(Aicda-cre)9Mbu Gt(ROSA)26Sor Resource Report Resource Website Issue Issue |
RRID:IMSR_RBRC05550 | Mus musculus |
B6.Cg-Gt(ROSA)26Sor |
gene symbol note: activation-induced cytidine deaminase|gene trap ROSA 26; Philippe Soriano||transgene insertion 9; Meinrad Busslinger|immunoglobulin heavy constant mu; mutant stock: Aicda|Gt(ROSA)26Sor||Tg(Aicda-cre)9Mbu|Ighm | activation-induced cytidine deaminase|gene trap ROSA 26; Philippe Soriano||transgene insertion 9; Meinrad Busslinger|immunoglobulin heavy constant mu | activation-induced cytidine deaminase|targeted mutation 1; Stuart Orkin||transgene insertion 9; Meinrad Busslinger|targeted mutation 1; University of Cologne | RBRC05550 | RIKEN BioResource Research Center | RBRC | embryo | 2026-02-14 12:53:56 | 0 | ||||
|
STOCK Gpd2tm1Tka Slc25a13tm1Lct/Mmjax Resource Report Resource Website Issue |
RRID:MMRRC_069611-JAX | Mus musculus | Research areas: Metabolism, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection: | hypoglycemia [MP:0000189]| decreased body weight [MP:0001262]| increased circulating free fatty acid level [MP:0001554]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| decreased circulating insulin level [MP:0002727]| increased circulating alkaline phosphatase level [MP:0002968]| abnormal gluconeogenesis [MP:0003383]| increased circulating glycerol level [MP:0003443]| increased circulating ammonia level [MP:0005309]| abnormal circulating amino acid level [MP:0005311]| abnormal amino acid level [MP:0005332]| increased liver triglyceride level [MP:0009355]| abnormal blood homeostasis [MP:0009642]| abnormal urine homeostasis [MP:0009643]| hypoglycemia [MP:0000189]| decreased body weight [MP:0001262]| decreased body size [MP:0001265]| abnormal eating behavior [MP:0001431]| increased circulating free fatty acid level [MP:0001554]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| decreased circulating insulin level [MP:0002727]| increased circulating alkaline phosphatase level [MP:0002968]| decreased insulin secretion [MP:0003059]| increased circulating glycerol level [MP:0003443]| increased circulating cholesterol level [MP:0005178]| decreased oxygen consumption [MP:0005290]| increased circulating ammonia level [MP:0005309]| abnormal circulating amino acid level [MP:0005311]| abnormal amino acid level [MP:0005332]| abnormal triiodothyronine level [MP:0005472]| increased circulating thyroxine level [MP:0005477]| increased circulating triiodothyronine level [MP:0005480]| increased body temperature [MP:0005533]| decreased brown fat cell lipid droplet size [MP:0009125]| increased liver triglyceride level [MP:0009355]| abnormal blood homeostasis [MP:0009642]| impaired adaptive thermogenesis [MP:0011049]| decreased brown adipose tissue mass [MP:0014169] | |Gpd2||Slc25a13 | 069611-JAX | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:17591776 PMID:14701727 |
MMRRC_69611-JAX, MMRRC_069611, MMRRC_69611 | 2026-02-14 07:54:00 | 0 | |||
|
C.129-Slc25a13tm1Lct/SinaMmjax Resource Report Resource Website Issue |
RRID:MMRRC_069594-JAX | Mus musculus | Research areas: Metabolism; Mutation Type: Targeted Mutation ; Collection: | hypoglycemia [MP:0000189]| decreased body weight [MP:0001262]| increased circulating free fatty acid level [MP:0001554]| postnatal growth retardation [MP:0001732]| premature death [MP:0002083]| hepatic steatosis [MP:0002628]| decreased circulating insulin level [MP:0002727]| increased circulating alkaline phosphatase level [MP:0002968]| abnormal gluconeogenesis [MP:0003383]| increased circulating glycerol level [MP:0003443]| increased circulating ammonia level [MP:0005309]| abnormal circulating amino acid level [MP:0005311]| abnormal amino acid level [MP:0005332]| increased liver triglyceride level [MP:0009355]| abnormal blood homeostasis [MP:0009642]| abnormal urine homeostasis [MP:0009643] | Slc25a13 | 069594-JAX | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:14701727 | MMRRC_69594-JAX, MMRRC_069594, MMRRC_69594 | 2026-02-14 07:53:45 | 0 | |||
|
B6.Cg-Tg(Nes-cre)1Kln/MullMmmh Resource Report Resource Website Issue |
RRID:MMRRC_031750-MU | Mus musculus | Research areas: ; Mutation Type: Transgenic ; Collection: Neuroscience Blueprint | Nes|cre| | 031750-MU | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_31750-MU, MMRRC_031750, MMRRC_3175 | 2026-02-14 07:43:16 | 0 | |||||
|
B6.Cg-B2mtm1Jae Tap1tm1Hpl/Mmucd Resource Report Resource Website Issue |
RRID:MMRRC_032245-UCD | Mus musculus | Research areas: Immunology and Inflammation, Neurobiology; Mutation Type: Targeted Mutation ; Collection: | decreased hematocrit [MP:0000208]| enlarged spleen [MP:0000691]| enlarged lymph nodes [MP:0000702]| dermatitis [MP:0001194]| decreased body size [MP:0001265]| reduced long term depression [MP:0001475]| anemia [MP:0001577]| abnormal long term depression [MP:0001898]| abnormal glucose homeostasis [MP:0002078]| abnormal T cell differentiation [MP:0002145]| abnormal lymph node morphology [MP:0002339]| abnormal double-positive T cell morphology [MP:0002408]| abnormal CD8-positive [MP:0002436]| alpha-beta cytotoxic T cell morphology [MP:0002461]| increased immunoglobulin level [MP:0002493]| increased IgG level [MP:0002494]| increased IgM level [MP:0002722]| abnormal immune system organ morphology [MP:0003008]| enhanced long term potentiation [MP:0003306]| small intestinal inflammation [MP:0003944]| abnormal T cell subpopulation ratio [MP:0004165]| abnormal lateral geniculate nucleus morphology [MP:0004753]| abnormal miniature excitatory postsynaptic currents [MP:0004792]| abnormal synaptic vesicle number [MP:0005026]| decreased susceptibility to parasitic infection [MP:0005078]| abnormal cytotoxic T cell physiology [MP:0005348]| increased T cell proliferation [MP:0005638]| hemochromatosis [MP:0008071]| absent B cells [MP:0008074]| increased CD4-positive [MP:0008075]| alpha beta T cell number [MP:0008077]| decreased CD4-positive [MP:0008078]| alpha beta T cell number [MP:0008079]| abnormal CD8-positive [MP:0008080]| alpha-beta T cell number [MP:0008097]| increased CD8-positive [MP:0008101]| alpha-beta T cell number [MP:0008346]| decreased CD8-positive [MP:0008350]| alpha-beta T cell number [MP:0008535]| abnormal CD8-positive [MP:0008560]| alpha-beta T cell differentiation [MP:0008571]| increased plasma cell number [MP:0008696]| lymph node hypoplasia [MP:0008700]| increased gamma-delta T cell number [MP:0008751]| increased gamma-delta intraepithelial T cell number [MP:0008752]| enlarged lateral ventricles [MP:0009538]| reduced long term depression [MP:0001475]| abnormal long term depression [MP:0001898]| increased tumor incidence [MP:0002020]| enhanced long term potentiation [MP:0003008]| abnormal lateral geniculate nucleus morphology [MP:0004165]| abnormal miniature excitatory postsynaptic currents [MP:0004753]| abnormal synaptic vesicle number [MP:0004792]| increased lung tumor incidence [MP:0008014]| enlarged lateral ventricles [MP:0008535]| abnormal synaptic bouton morphology [MP:0008571]| increased uterus tumor incidence [MP:0009222]| abnormal synapse morphology [MP:0009538]| increased gastrointestinal tumor incidence [MP:0010279]| increased mammary gland tumor incidence [MP:0010299]| increased skin tumor incidence [MP:0010300] | |B2m||Tap1 | 032245-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11118151 PMID:17420446 PMID:9548460 PMID:2685607 PMID:8643655 |
MMRRC_32245-UCD, MMRRC_032245, MMRRC_32245 | 2026-02-14 07:43:36 | 0 | |||
|
NOD.Cg-Cd28tm1Mak Cd40tm1Kik Ifngtm1Ts H2h4/HbmMmmh Resource Report Resource Website 1+ mentions Issue |
RRID:MMRRC_037143-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen | increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466]| decreased bone mineral density [MP:0000063]| decreased neutrophil cell number [MP:0000222]| enlarged spleen [MP:0000691]| enlarged lymph nodes [MP:0000702]| abnormal humoral immune response [MP:0001800]| decreased IgA level [MP:0001807]| no abnormal phenotype detected [MP:0002169]| abnormal thymus medulla morphology [MP:0002375]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| decreased IgE level [MP:0002492]| glomerulonephritis [MP:0002743]| increased urine protein level [MP:0002962]| increased anti-double stranded DNA antibody level [MP:0004762]| abnormal class switch recombination [MP:0004816]| decreased B cell number [MP:0005017]| decreased susceptibility to type II hypersensitivity reaction [MP:0005612]| decreased cerebral infarction size [MP:0006058]| increased follicular B cell number [MP:0008173]| absent germinal center B cells [MP:0008179]| increased marginal zone B cell number [MP:0008181]| increased transitional stage B cell number [MP:0008189]| abnormal B cell activation [MP:0008217]| absent spleen germinal center [MP:0008474]| decreased IgG1 level [MP:0008495]| decreased IgG2a level [MP:0008496]| decreased IgG2b level [MP:0008497]| decreased IgG3 level [MP:0008498]| abnormal thymus epithelium morphology [MP:0009544]| decreased platelet aggregation [MP:0009549]| decreased trabecular bone mass [MP:0010873]| decreased compact bone mass [MP:0010962]| renal glomerular immunoglobulin deposits [MP:0020519]| abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874]| abnormal esophageal epithelium morphology [MP:0000468]| enlarged thymus [MP:0000709]| increased activated T cell number [MP:0001829]| brain inflammation [MP:0001847]| increased T cell derived lymphoma incidence [MP:0002024]| abnormal T cell differentiation [MP:0002145]| abnormal lymphopoiesis [MP:0002401]| decreased immunoglobulin level [MP:0002460]| abnormal cytokine secretion [MP:0003009]| esophageal inflammation [MP:0003278]| insulitis [MP:0004031]| increased length of allograft survival [MP:0004751]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| increased susceptibility to autoimmune diabetes [MP:0004803]| abnormal class switch recombination [MP:0004816]| abnormal regulatory T cell physiology [MP:0004946]| decreased regulatory T cell number [MP:0004974]| abnormal T cell clonal deletion [MP:0005002]| increased eosinophil cell number [MP:0005011]| increased susceptibility to parasitic infection [MP:0005027]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased cytotoxic T cell cytolysis [MP:0005079]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005465]| abnormal T-helper 1 physiology [MP:0005466]| abnormal T-helper 2 physiology [MP:0005596]| increased susceptibility to type I hypersensitivity reaction [MP:0005671]| abnormal response to transplant [MP:0006413]| increased T cell apoptosis [MP:0008049]| increased memory T cell number [MP:0008074]| increased CD4-positive [MP:0008078]| alpha beta T cell number [MP:0008192]| increased CD8-positive [MP:0008482]| alpha-beta T cell number [MP:0008495]| abnormal germinal center B cell physiology [MP:0008496]| decreased spleen germinal center number [MP:0008497]| decreased IgG1 level [MP:0008500]| decreased IgG2a level [MP:0008566]| decreased IgG2b level [MP:0008567]| increased IgG2a level [MP:0008578]| increased interferon-gamma secretion [MP:0008603]| decreased interferon-gamma secretion [MP:0008687]| decreased circulating interferon-gamma level [MP:0008688]| decreased circulating interleukin-4 level [MP:0008699]| increased interleukin-2 secretion [MP:0008700]| decreased interleukin-2 secretion [MP:0008747]| increased interleukin-4 secretion [MP:0009335]| decreased interleukin-4 secretion [MP:0010268]| abnormal T cell anergy [MP:0010766] | Cd28||Ifng||Cd40||| | 037143-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_37143-MU, MMRRC_037143, MMRRC_37143 | 2026-02-14 07:44:21 | 1 |
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