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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Centrifuge Classifier
 
Resource Report
Resource Website
1+ mentions
Centrifuge Classifier (RRID:SCR_016665) software application, data processing software, sequence analysis software, data analysis software, software resource Software for rapid and sensitive classification of metagenomic sequences. Used for the classification of DNA sequences from microbial samples and analysis of large metagenomics data sets on conventional desktop computers. classification, large, metagenomic, sequence, DNA, microbial, sample, analysis, data, desktop, computer, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is related to: Pavian
has parent organization: Center for Computational Biology at JHU
U. S. Army Research Office W911NF1410490;
NSF ABI1356078;
NHGRI R01 HG006677;
NIGMS R01 GM083873
DOI:10.1101/gr.210641.116 Free, Available for download, Freely available biotools:centrifuge, OMICS_12217 https://github.com/infphilo/centrifuge
https://bio.tools/centrifuge
https://sources.debian.org/src/centrifuge/
SCR_016665 2026-02-16 09:49:05 9
Pavian
 
Resource Report
Resource Website
10+ mentions
Pavian (RRID:SCR_016679) data analysis service, analysis service resource, web application, software resource, production service resource, service resource Software R package for interactive analysis of metagenomics classification results with a special focus on infectious disease diagnosis. Used for analyzing and visualization of metagenomics classification results from classifiers such as Kraken, Centrifuge and MetaPhlAn. Provides an alignment viewer for validation of matches to a particular genome. interactive, analysis, metagenomics, classification, result, infectious, disease, diagnosis, data, visualization, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Centrifuge Classifier
NHGRI R01 HG006677;
NIGMS R01 GM083873;
U. S. Army Research Office W911NF1410490
DOI:10.1101/084715 Free, Freely available biotools:pavian https://fbreitwieser.shinyapps.io/pavian/
https://bio.tools/pavian
SCR_016679 2026-02-16 09:49:05 22
KnowEnG
 
Resource Report
Resource Website
1+ mentions
KnowEnG (RRID:SCR_016875) training resource, organization portal, software resource, portal, data or information resource Part of the NIH Big Data to Knowledge (BD2K) Initiative. One of 11 Centers of Excellence in Big Data Computing. Platform for genomics data analysis where user-supplied data sets will be analyzed in the context of existing knowledge. E-science framework for genomics where biomedical scientists will have access to powerful methods of data mining, network mining, and machine learning to extract knowledge out of genomics data. center, excellence, big, data, computing, biomedical, analytics has parent organization: Mayo Clinic
has parent organization: University of Illinois at Urbana-Champaign; Illinois; USA
NIGMS U54 GM114838 PMID:26205246 https://github.com/BD2K/KnowEng SCR_016875 Knowledge Engine for Genomics, The Knowledge Engine for Genomics 2026-02-16 09:49:06 1
CheckMyMetal
 
Resource Report
Resource Website
1+ mentions
CheckMyMetal (RRID:SCR_016887) CMM data access protocol, software resource, web service Metal binding site validation server. Used for systematic inspection of the metal-binding architectures in macromolecular structures. The validation parameters that CMM examines cover the entire binding environment of the metal ion, including the position, charge and type of atoms and residues surrounding the metal. metal, binging, site, validation, server, systematic, inspection, macromolecular, structure, ion, charge, position, atom NIGMS GM117325;
NHGRI HG008424;
NIAID HHSN272201200026C
PMID:28291757 Free, Freely available SCR_016887 2026-02-16 09:49:07 5
exRNA Atlas
 
Resource Report
Resource Website
10+ mentions
exRNA Atlas (RRID:SCR_017221) application programming interface, controlled vocabulary, organization portal, data analysis service, analysis service resource, data access protocol, atlas, ontology, data repository, software resource, database, storage service resource, expression atlas, consortium, portal, production service resource, service resource, data or information resource Software tool as data and metadata repository of Extracellular RNA Communication Consortium. Atlas includes small RNA sequencing and qPCR derived exRNA profiles from human and mouse biofluids. All RNAseq datasets are processed using version 4 of exceRpt small RNAseq pipeline. Atlas accepts submissions for RNAseq or qPCR data. Differential, expression, RNA, sequencing, qPCR, data, visualization, extracellular, exRNA, atlas, repository, dataset is recommended by: National Library of Medicine
has parent organization: Baylor College of Medicine; Houston; Texas
has parent organization: exRNA
gastric cancer, colon carcinoma, colorectal cancer, prostate carcinoma, pancreatic carcinoma, multiple sclerosis, glioblastoma multiforme, ulcerative colitis, Alzheimer's disease, ischemic stroke, intraparenchymal hemorrhage of brain, asthma, cardiovascular disorder, myocardial infarction, lupus, nephrotic syndrome, transplanted kidney present, liver disease, transplanted liver present, pre-eclampsia, Parkinson disease, intraventricular brain hemorrhage, subarachnoid hemorrhage NIDA U54 DA036134;
NCI R01 CA163849;
NIGMS R25 GM056929;
NCATS UH3 TR000906;
NCI U19 CA179512;
NIDDK P30 DK63720;
NHLBI K23 HL127099;
NHLBI R01 HL136685;
NIA R01 AG059729;
NCATS UH3 TR000943;
NCI R35 CA209904;
NCI CA217685;
NHLBI R01 HL122547;
American Cancer Society ResearchProfessor Award ;
Frank McGraw Memorial Chair in CancerResearch
PMID:30951672 Restricted SCR_017221 2026-02-16 09:49:11 24
RNAstructure
 
Resource Report
Resource Website
10+ mentions
RNAstructure (RRID:SCR_017216) software application, web service, data access protocol, analysis service resource, software resource, simulation software, production service resource, service resource Web server for RNA and DNA secondary structure prediction and analysis. Software package as RNA folding prediction program. RNA, DNA, secondary, structure, prediction, analysis is listed by: SoftCite
has parent organization: University of Rochester; New York; USA
NIGMS R01 GM076485 PMID:23620284 Free, Freely available SCR_017216 2026-02-16 09:49:11 42
CCPN Data Model
 
Resource Report
Resource Website
CCPN Data Model (RRID:SCR_016982) software application, data processing software, data repository, database, storage service resource, software resource, data storage software, service resource, data or information resource Model to cover data for macromolecular NMR spectroscopy from the initial experimental data to the final validation. Used for the large scale data deposition, data mining and program interoperability. Enables movement from one software package to another without difficulties with data conversion or loss of information. Works with CcpNmr Analysis software for analysis and interactive display, CcpNmr FormatConverter for allowing transfer of data from programs used in NMR to and from the Data Model, and the CLOUDS software for automated structure calculation and assignment. Used within the CCPN software suite for NMR spectroscopy and at the BioMagResBank for converting existing deposited restraint lists to a standard IUPAC nomenclature. data, macromolecular, NMR, spectroscopy, deposition, mining, interoperability, conversion is related to: Biological Magnetic Resonance Data Bank (BMRB)
has parent organization: Collaborative Computing Project for NMR
works with: CCPN Analysis
works with: CCPN Analysis
EU ;
BBSRC ;
NLM P41 LM005799;
NIGMS GM67965
PMID:15815974
PMID:15613391
PMID:21953355
Free, Public SCR_016982 The CCPN Data Model 2026-02-16 09:49:08 0
eMERGE Network: electronic Medical Records and Genomics
 
Resource Report
Resource Website
1+ mentions
eMERGE Network: electronic Medical Records and Genomics (RRID:SCR_007428) eMERGE data or information resource, topical portal, portal A national consortium formed to develop, disseminate, and apply approaches to research that combine DNA biorepositories with electronic medical record (EMR) systems for large-scale, high-throughput genetic research. The consortium is composed of seven member sites exploring the ability and feasibility of using EMR systems to investigate gene-disease relationships. Themes of bioinformatics, genomic medicine, privacy and community engagement are of particular relevance to eMERGE. The consortium uses data from the EMR clinical systems that represent actual health care events and focuses on ethical issues such as privacy, confidentiality, and interactions with the broader community. human, clinical, dna, alzheimer's disease, genome, genomics, gene, genetic, nervous system disease, nucleotide polymorphism, phenotype, bioinformatics, genomic medicine, privacy, community engagement, emr, electronic medical record is related to: PheKB
is related to: NCBI database of Genotypes and Phenotypes (dbGap)
is related to: PheWAS Catalog
has parent organization: Vanderbilt University; Tennessee; USA
Aging NIGMS ;
NHGRI
Available to the research community nif-0000-00539 SCR_007428 eMERGE Network: electronic Medical Records & Genomics - A consortium of biorepositories linked to electronic medical records data for conducting genomics studies, eMERGE Network: electronic Medical Records Genomics, eMERGE Network: electronic Medical Records & Genomics, eMERGE Network, electronic Medical Records & Genomics, The eMERGE Network: electronic Medical Records & Genomics 2026-02-16 09:46:58 2
SimTKCore
 
Resource Report
Resource Website
SimTKCore (RRID:SCR_008268) SimTKCore software application, software resource, simulation software SimTK Core is one of the two packages that together constitute SimTK, the biosimulation toolkit from the Simbios Center. The other major component of SimTK is OpenMM which is packaged separately. This SimTK Core project collects together all the binaries needed for the various SimTK Core subprojects. These include Simbody, Molmodel, Simmath (including Ipopt), Simmatrix, CPodes, SimTKcommon, and Lapack. See the individual projects for descriptions. SimTK brings together in a robust, convenient, open source form the collection of highly-specialized technologies necessary to building successful physics-based simulations of biological structures. These include: strict adherence to an important set of abstractions and guiding principles, robust, high-performance numerical methods, support for developing and sharing physics-based models, and careful software engineering. Accessible High Performance Computing We believe that a primary concern of simulation scientists is performance, that is, speed of computation. We seek to build valid, approximate models using classical physics in order to achieve reasonable run times for our computational studies, so that we can hope to learn something interesting before retirement. In the choice of SimTK technologies, we are focused on achieving the best possible performance on hardware that most researchers actually have. In today''s practice, that means commodity multiprocessors and small clusters. The difference in performance between the best methods and the do-it-yourself techniques most people use can be astoundingeasily an order of magnitude or more. The growing set of SimTK Core libraries seeks to provide the best implementation of the best-known methods for widely used computations such as: Linear algebra, numerical integration and Monte Carlo sampling, multibody (internal coordinate) dynamics, molecular force field evaluation, nonlinear root finding and optimization. All SimTK Core software is in the form of C++ APIs, is thread-safe, and quietly exploits multiple CPUs when they are present. The resulting pre-built binaries are available for download and immediate use. Audience: Biosimulation application programmers interested in including robust, high-performance physics-based simulation in their domain-specific applications. computational algorithm, high-performance, linear algebra, numerical integration, numerical method, optimization, monte carlo sampling, multibody dynamics, molecular force field evaluation, nonlinear root finding, optimizing, cpodes, simbody, ipopt, molmodel, mit license, linux, mac os x, windows is listed by: Biositemaps
has parent organization: Stanford University; Stanford; California
has parent organization: Simtk.org
NIGMS U54 GM072970 PMID:20107615 nif-0000-23310 SCR_008268 2026-02-16 09:47:08 0
Hippocampal Slice Wave Animations
 
Resource Report
Resource Website
Hippocampal Slice Wave Animations (RRID:SCR_008372) software application, data processing software, data visualization software, simulation software, resource, software resource, topical portal, animation software, portal, data or information resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 29, 2013. Supplemental data for the paper Changes in mitochondrial function resulting from synaptic activity in the rat hippocampal slice, by Vytautas P. Bindokas, Chong C. Lee, William F. Colmers, and Richard J. Miller that appears in the Journal of Neuroscience June 15, 1998. You can view digital movies of changes in fluorescence intensity by clicking on the title of interest. animation, hippocampal, hippocampus, mitochondrial, movie, neuroscience, rat, slice, wave MRC of Canada MT10520;
NIDA DA02575;
NIDA DA02121;
NIMH MH40165;
NIDDK DK42086;
NIDDK DK44840;
NINDS NS-33502;
NIGMS 5T32GM07151-22;
NICHD HD07009
PMID:9614233 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-25609 SCR_008372 GIF Animations 2026-02-16 09:47:10 0
MODELLER
 
Resource Report
Resource Website
5000+ mentions
MODELLER (RRID:SCR_008395) software application, portal, software resource, topical portal, simulation software, data or information resource Software tool as Program for Comparative Protein Structure Modelling by Satisfaction of Spatial Restraints. Used for homology or comparative modeling of protein three dimensional structures. User provides alignment of sequence to be modeled with known related structures and MODELLER automatically calculates model containing all non hydrogen atoms. comparative, protein, structure, modelling, satisfaction, spatial, restrain, homology, 3D, alignment, sequence, hydrogen, atom, cluster is listed by: SoftCite
has parent organization: University of California at San Francisco; California; USA
Sandler Family Supporting Foundation ;
NIGMS R01 GM54762;
NIGMS P01 GM71790;
NIH P01 A135707;
NIGMS U54 GM62529;
IBM ;
Intel
Restricted nif-0000-30054 SCR_008395 2026-02-16 09:47:10 5736
SerialEM
 
Resource Report
Resource Website
100+ mentions
SerialEM (RRID:SCR_017293) data acquisition software, software application, data processing software, software resource Software tool for automated EM data acquisition. Used for efficient tilt series acquisition and interface for image capture, display, and storage and for control of some aspects of microscope function. automated, data, acquisition, tilt, image, capture, display, storage, microscope NCRR RR00592;
NIGMS P01 GM61306
PMID:16182563 Restricted SCR_017293 2026-02-16 09:49:12 213
Protomo
 
Resource Report
Resource Website
1+ mentions
Protomo (RRID:SCR_017296) data processing software, software application, software resource, image processing software Software tool for electron tomography and 3D image processing. Software package used in electron tomography for marker free alignment and 3D reconstruction of tilt series. Tomography software package distributed for linux operating system and developed by Hanspeter Winkler. electron, tomography, 3D, image, processing NIGMS GM30598;
NIGMS GM64346
PMID:16973379 Restricted SCR_017296 2026-02-16 09:49:12 4
RaptorX
 
Resource Report
Resource Website
100+ mentions
RaptorX (RRID:SCR_018118) software application, web service, data access protocol, software resource, simulation software Software package and web server for protein structure and function prediction. Used for predicting 3D structures for protein sequences without close homologs in Protein Data Bank. Given input sequence, predicts its secondary and tertiary structures, contacts, solvent accessibility, disordered regions and binding sites. Assigns some confidence scores to indicate quality of predicted 3D model. Protein structure predictor, 3D structure, protein sequence, secondary and tertiary structure, binding site, solvent accessibility, disordered region, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Chicago; Illinois; USA
NIGMS R01 GM089753;
NSF DBI 0960390
PMID:21987485 Restricted biotools:raptorx https://bio.tools/raptorx SCR_018118 2026-02-16 09:49:26 149
piNET
 
Resource Report
Resource Website
1+ mentions
piNET (RRID:SCR_018693) web service, data access protocol, analysis service resource, software resource, production service resource, service resource Web platform for downstream analysis and visualization of proteomics data. Server that facilitates integrated annotation, analysis and visualization of quantitative proteomics data, with emphasis on PTM networks and integration with LINCS library of chemical and genetic perturbation signatures in order to provide further mechanistic and functional insights. Primary input for server consists of set of peptides or proteins, optionally with PTM sites, and their corresponding abundance values. Analysis, visualization, proteomics data, integrated annotation, quantitative proteomics data, PTM network, LINCS library integration, genetic perturbation signature, peptide, protein, post translational modification site, PTM site, data is related to: LINCS Project NHLBI U54 HL127624;
NIEHS P30 ES006096;
NIMH R01 MH107487;
NCI T32 CA236764;
NCATS UL1 TR001425;
NIGMS U01 GM120953
DOI:10.1093/nar/gkaa436 Free, Freely available SCR_018693 2026-02-16 09:49:33 4
Monocle3
 
Resource Report
Resource Website
100+ mentions
Monocle3 (RRID:SCR_018685) software application, data processing software, software toolkit, data analysis software, software resource Software analysis toolkit for single cell RNA-seq. Used for single cell RNA-Seq experiments. Unsupervised algorithm that increases temporal resolution of transcriptome dynamics using single-cell RNA-Seq data collected at multiple time points. Data analysis, singel cell RNAseq data, single cell RNAseq experiment, transcriptome dynamics has parent organization: University of Washington; Seattle; USA NIH Office of the Director DP2 OD00667;
NIGMS P01 GM099117;
NIH Office of the Director DP2 0D008514;
NHGRI P50 HG006193;
Single Cell Genomics initiative
PMID:24658644 Free, Available for download, Freely available https://github.com/cole-trapnell-lab/monocle3 SCR_018685 Monocle, Monocle 3 2026-02-16 09:49:31 270
BpForms
 
Resource Report
Resource Website
BpForms (RRID:SCR_018653) data access protocol, software resource, web service, software toolkit Software toolkit for unambiguously describing molecular structure of DNA, RNA, and proteins, including non-canonical monomeric forms, crosslinks, nicks, and circular topologies. Aims to help epigenomics, transcriptomics, proteomics, systems biology, and synthetic biology researchers share and integrate information about DNA modification, post-transcriptional modification, post-translational modification, expanded genetic codes, and synthetic parts. Molecular structure description, DNA, RNA, protein, modification, epigenetics, transcriptomics, post transcriptional modification, post translational modification, bio.tools uses: BcForms
is used by: ObjTables
is used by: Datanator
is listed by: Debian
is listed by: bio.tools
is related to: BcForms
is related to: ObjTables
NIBIB P41 EB023912;
NSF 1649014;
NIGMS R35 GM119771
PMID:32423472 Free, Freely available biotools:bpforms https://bio.tools/bpforms SCR_018653 2026-02-16 09:49:30 0
ObjTables
 
Resource Report
Resource Website
ObjTables (RRID:SCR_018652) software application, data processing software, software toolkit, data management software, software resource Software toolkit for creating reusable datasets that are both human and machine readable, combining spreadsheets with schemas including classes, their attributes, type of each attribute, and possible relationships between instances of classes.Consists of format for describing schemas for spreadsheets, numerous data types for science, syntax for indicating class and attribute represented by each table and column in workbook, and software for using schemas to rigorously validate, merge, split, compare, and revision datasets. Used for supplementary materials of journal article, as well as for emerging domains which need to quickly build new formats for new types of data and associated software with minimal effort. Creating reusable dataset, combining spreadsheet with schema, spreadsheet, table, supplementary material, schema, object relational map, validation, bio.tools uses: BpForms
uses: BcForms
is listed by: bio.tools
is listed by: Debian
is related to: BpForms
NIBIB P41 EB023912;
NSF 1649014;
NIGMS R35 GM119771
Free, Freely available biotools:objtables https://bio.tools/objtables SCR_018652 2026-02-16 09:49:33 0
PhyDyn
 
Resource Report
Resource Website
10+ mentions
PhyDyn (RRID:SCR_018544) software application, software resource, simulation software Sofware package for performing Bayesian phylogenetic inference under models that deal with structured populations with complex population dynamics. Enables simultaneous estimation of epidemiological parameters and pathogen phylogenies. Epidemiological modelling in BEAST. Bayesian phylogenetic inference, epidemiological modelling, epidemiological parameter estimation, pathogen phylogeny estimation is related to: BEAST2
is related to: BEAST
NIGMS U01 GM110749;
MRC Centre for Global Infectious Disease Analysis
PMID:30422979 Free, Available for download, Freely available SCR_018544 2026-02-16 09:49:31 10
MyGene.info
 
Resource Report
Resource Website
10+ mentions
MyGene.info (RRID:SCR_018660) service resource, data access protocol, software resource, web service Web service for querying or retrieving gene annotation data. Querying gene, gene, annotation, gene annotation, annotation data, gene annotation data, retrieving gene annotation data, bio.tools is listed by: Debian
is listed by: bio.tools
NHGRI U01 HG008473;
NIGMS GM083924;
NIGMS U54 GM114833;
NHGRI U01 HG006476;
NCI K22 CA188163;
NCATS UL1 TR001114;
Scripps Translational Science Institute
DOI:10.1186/s13059-016-0953-9 Free, Freely available biotools:mygene.info, BioTools:mygene.info https://bio.tools/mygene.info
https://bio.tools/mygene.info
https://bio.tools/mygene.info
SCR_018660 2026-02-16 09:49:30 20

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