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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.ionpath.com/mibiscope/
Imaging platform, enabling phenotypic profiling and spatial analysis of tissue microenvironment. Enables over 40 markers to be visualized simultaneously with single step staining and single step imaging.
Proper citation: Ionpath MIBIscope System (RRID:SCR_023613) Copy
https://www.htximaging.com/htx-m5-sprayer
Sprayer builds on capabilities of HTX TM-Sprayer providing innovative M5 chassis, high velocity stage and heated sample holder drawer. Sample plate holder is mounted on drawer mechanism to allow easy loading of samples, better protection of user and better alignment of various plate types. New High-Velocity XY stage allows nozzle displacement speed of up to 5,600mm/min and expands process range. Super dry spray can be achieved at high flow rates of solvent further improving instrument performance. E/Z trough gutter design improves chemical containement and is easy to remove and clean. Bulkhead connectors are directly mounted on it to also allow easy access to in line filter.
Proper citation: HTX M5 Sprayer (RRID:SCR_023733) Copy
https://www.htximaging.com/tm-sprayer
Allows users to adjust both gas flow rate and nozzle velocity to control drying time, preventing analyte delocalization and formation of large matrix crystals, known to create hot spots on MALDI images. Allows to heat matrix solution as it is being applied to their sample. By increasing temperature of matrix solution, absorption of matrix into sample is increased, resulting in greater MALDI image resolution.
Proper citation: HTX TM-Sprayer (RRID:SCR_023732) Copy
https://andor.oxinst.cn/products/scmos-camera-series/zyla-4-2-scmos
Zyla 4.2 PLUS is the latest sCMOS technology advancement from Andor. At its heart, Zyla 4.2 PLUS benefits from latest generation sCMOS sensor technology, delivering a further 10 % boost in QE, resulting in an unprecedented 82% QEmax.
Proper citation: Andor Zyla 4.2 sCMOS (RRID:SCR_023610) Copy
https://www.htximaging.com/htx-m3-sprayer
Sample preparation platform offering automated advanced MALDI matrix sprayer.
Proper citation: HTX M3+ Sprayer (RRID:SCR_023731) Copy
Mass spectrometer designed for most difficult analytical challenges. Incorporates inventions in ion transmission and control, extended m/z range, and real-time decision making. System suited for proteomics, structural biology, small-molecule, and biopharmaceutical characterization experiments.
Proper citation: Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer (RRID:SCR_023618) Copy
Inverted microscope Axio Observer 3 for transmitted light brightfield LED and differential interference contrast. Used for demanding multimodal imaging.
Proper citation: Zeiss Axio Observer 3 (RRID:SCR_023693) Copy
https://www.ttuhsc.edu/pharmacy/research/documents/Amnis-Imagestream-Manual.pdf
Bench top multispectral imaging flow cytometer designed for the acquisition of up to 12 channels of cellular imagery. It combines per cell information with statistical significance of sample sizes of standard flow cytometry.
Proper citation: Luminex Amnis ImageStreamX Mk II System (RRID:SCR_018589) Copy
https://atagousa.corecommerce.com/PAL-10S-p358.html
Digital hand held pocket refractometer that measures urine specific gravity. It has measurement temperature of 10 to 35 C and sample volume of 0.3ml.
Proper citation: Atago PAL-10S Pocket Refractometer (RRID:SCR_018439) Copy
https://www.sutter.com/manuals/P-2000_OpMan.pdf
Microprocessor controlled, CO2 laser based micropipette puller.Default configuration allows fabrication of micropipettes for intracellular recording, patch clamping, microinjection and microperfusion.Can store up to 100 separate programs, each consisting of up to 8 command lines. The five parameters set in each command line allow exquisite control of the micropipette taper geometry. Allows the use of wide range of glass diameters from 0.125 to 1.2 mm.
Proper citation: Sutter P-2000 Laser Micropipette Puller (RRID:SCR_018640) Copy
http://tools.thermofisher.com/content/sfs/manuals/nd-1000-v3.8-users-manual-8%205x11.pdf
Spectrophotometer for measurement and analysis of 1 ul samples with high accuracy and reproducibility. Full spectrum from 220nm to 750nm spectrophotometer utilizes patented sample retention technology that employs surface tension alone to hold sample in place. No need for cuvettes. Has capability to measure highly concentrated samples without dilution.
Proper citation: Thermo Scientific Nanodrop 1000 Spectrophotometer (RRID:SCR_016517) Copy
Benchtop genetic analyzer. Electrophoresis system for DNA and RNA sample quality control. It can be used for next generation sequencing or Biobank workflow.
Proper citation: Agilent 4200 TapeStation System (RRID:SCR_018435) Copy
http://tools.thermofisher.com/content/sfs/manuals/cms_040970.pdf
Automated PCR instrument for automated amplification of nucleic acids with Polymerase Chain Reaction. It has reaction volumes of up to 50 uL and sample temperature range of 4 to 99.9 C.
Proper citation: Applied Biosystems GeneAmp 9700 PCR Thermocycler System (RRID:SCR_018436) Copy
https://pathology.med.upenn.edu/research/core-resources/tumor-tissue-biospecimen-bank
Centralized biorepository of human biosamples. TTAB is responsible for the collection, processing, and storage of human blood, fluid, and tissue at the University of Pennsylvania Health System. TTAB has a collection bench within Surgical Pathology Suite at Hospital of University of Pennsylvania (HUP).� Our collection bench sits adjacent to frozen section teams managing clinical sample collection and allowing for tight integration of tissue sample collection with clinical pathology teams.
Proper citation: University of Pennsylvania Perelman School of Medicine Tumor Tissue Biospecimen Bank Core Facility (RRID:SCR_022430) Copy
Integrated healthcare biobank that operates under certified conditions and strict SOPs. Enables biomedical and translational researchers to perform their analyses using high quality biospecimens and data to generate reliable and reproducible research data. Core offers modular biobanking portfolio that can cover workflow from blood collection to storage, including all pre-analytical steps and their documentation. Offers spectrum of additional services ranging from DNA/RNA extraction and virtual microscopy to entire management of sample and data flow for national and international research consortia. Provides secure conventional and automated storage of samples at various temperatures as well as secure data management.
Proper citation: Charite University and Berlin Institute for Health Research Central Biobank Core Facility (RRID:SCR_023495) Copy
Center coordinates ideas and investments to advance and democratize access to Stanford cores, instrumentation, scientific and technical staff, allowing users to perform innovative, rigorous experiments.
Proper citation: Stanford University Community of Shared Advanced Research Platforms (RRID:SCR_022986) Copy
https://timothyspringer.org/files/tas/files/biacore3000-instrument.pdf
Biacore 3000 processing unit is an established, label-free system for detailed studies of biomolecular interactions. The system delivers comprehensive characterization of the interaction, answers questions about the rate constants, affinity, specificity, and determines the active concentration of components. The ability to recover and transfer interaction partners directly to MALDI targets for identification and further characterization makes the system highly applicable to fast identification of unknown interactants.
Proper citation: Biacore 3000 Real Time Biomolecular Interaction Analyzer (RRID:SCR_018044) Copy
https://www.agilent.com/cs/library/brochures/5990-5596EN.pdf
Agilent 3100 OFFGEL Fractionator performs isoelectric focusing of proteins or peptides in immobilized pH gradient (IPG) gel strips.
Proper citation: Agilent 3100 OFFGEL Fractionator (RRID:SCR_018433) Copy
https://www.mines.edu/shared-facilities/project_category/nanofabrication/
Facility houses cleanrooms with processing equipment for making and characterizing electronic devices, thin film deposition tools for creation of metallic and ceramic thin film devices, and characterization lab with tools for surface, morphological, and optical characterization of materials.
Proper citation: Colorado School of Mines Shared Instrumentation Facility Surface Characterization and Thin Film Deposition Core Facility (RRID:SCR_022047) Copy
https://medschool.cuanschutz.edu/immunology-immunotherapy/phism
Core provides Human Immune System as preclinical in vivo model to study human immune system in experimental tractable animal model e.g. immune response to human tumors that readily grow in HIS-mice. Offers immune expertise, experimental procedures and data analysis of immune based assays, such as flow cytometry.
Proper citation: University of Colorado Anschutz Medical Campus Cancer Center PreClinical Human Immune System Mice Shared Resource Core Facility (RRID:SCR_021990) Copy
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