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https://www.birmingham.ac.uk/university/colleges/mds/facilities/intravital-microscopy-suite

Imaging facility for intravital microscopy. Facility equipment includes widefield, confocal, and multiphoton microscopes. Additional tools, such as laser ablation systems, allow us to probe vascular events such as thrombosis in fine detail. We also have tools for measurement of vascular perfusion, such as full-field laser speckle and laser doppler.

Proper citation: University of Birmingham Intravital Microscopy Core Facility (RRID:SCR_027189) Copy   

•   Source: SciCrunch Registry

https://www.umass.edu/ials/core-facilities/flow-cytometry

Core facility provides access to technologies in flow cytometry analysis including spectral analysis, high throughput imaging analysis (Amnis) and fluorescence assisted particle sorting (FACS). Instrument training, experiment and panel design, scientific consultation and sample processing are available. Offers training on facility equipment.

Proper citation: University of Massachusetts Flow Cytometry Core Facility (RRID:SCR_027100) Copy   

•   Source: SciCrunch Registry

https://www.birmingham.ac.uk/university/colleges/mds/facilities/protein-expression-facility

Core, within College of Medicine and Health, offers expert support for all aspects of recombinant protein production. Using range of expression systems, produces proteins suitable for diverse downstream applications.

Proper citation: University of Birmingham Protein Expression Core Facility (RRID:SCR_027106) Copy   

•   Source: SciCrunch Registry

https://www.goodmancancer.ca/en/mcgill-integrated-core-for-animal-modeling-micam

Core offers various services related to animal model generation and maintenance.

Proper citation: McGill University Integrated Core for Animal Modeling MICAM Core Facility (RRID:SCR_027118) Copy   

•   Source: SciCrunch Registry

https://mri.fsu.edu/

MRI facility is research-dedicated space that includes 3T Siemens Prisma (whole-body) scanner, an MR-compatible Brain Products system for EEG and psycho-physiological measures, eye tracker, mock scanner, and a MagPro X100 equipped with Localite TMS Navigator for brain stimulation.

Proper citation: Florida State University College of Medicine Magnetic Resonance Imaging Core Facility (RRID:SCR_027280) Copy   

•   Source: SciCrunch Registry

https://depressioncenter.org/research-services/mobile-technologies-core

Core provides University of Michigan investigators with guidance and resources needed to utilize mobile technologies and digital mental health measures in their studies. Our experienced faculty and staff offer hands-on consultative services to U-M investigators, regardless of research focus.

Proper citation: University of Michigan Eisenberg Family Depression Center Mobile Technologies Core Facility (RRID:SCR_027334) Copy   

•   Source: SciCrunch Registry

https://www.umichttml.org/

Core to enable the use of primary human tissue models for discovery, translation and regenerative medicine.

Proper citation: University of Michigan Translational Tissue Modeling Laboratory Core Facility (RRID:SCR_027333) Copy   

•   Source: SciCrunch Registry

https://aidhi.umich.edu/

Core with mission to harness data and expertise to power innovations that improve people’s health through unification and enhancement of interdisciplinary efforts at the intersection of artificial intelligence (AI) and health at the University of Michigan. Provides data services, secure computing resources, support to strategically integrate and study AI models in clinical workflows at Michigan Medicine.

Proper citation: University of Michigan AI and Digital Health Innovation Core Facility (RRID:SCR_027336) Copy   

•   Source: SciCrunch Registry

https://depressioncenter.org/research-services/data-design-core

Core staff provides personalized consultations, knowledge and resources focused on helping investigators leverage secondary data to advance their mental health research. Offers consultations and guide in areas:Identifying secondary data sources for mental health studies,Data preparation (e.g., merging/appending data, preparing variables for analysis), Developing analysis plan, including pre-registration, Statistical analysis.

Proper citation: University of Michigan Eisenberg Family Depression Center Data and Design Core Facility (RRID:SCR_027335) Copy   

•   Source: SciCrunch Registry

https://www.janelia.org/support-team/janelia-experimental-technology

Core team designs, builds and tests instruments, tools, and software that enable novel scientific investigation. Offers expertise in Data acquisition and analysis; Machine vision and image processing; Precision machining; Embedded systems design and programming; Laser, microscopy, and optical imaging systems engineering; Custom circuit design; Novel sensor systems; Lab automation, robotics and motion control; Mechanical design, machined and/or fabricated components and assemblies; Process automation.

Proper citation: Howard Hughes Medical Institute at Janelia Research Campus Janelia Experimental Technology jET Core Facility (RRID:SCR_027301) Copy   

•   Source: SciCrunch Registry

https://www.iqm.unicamp.br/institucional/infraestrutura/cemuiq/liafq/

Laboratory for Physicochemical Analysis of IQ-UNICAMP houses equipment for a range of analytical techniques:Thermal Analysis comprises techniques that measure the physical or chemical properties of a substance, or its reaction products, under controlled temperature variation;Atomic Spectrometry enables multi-element determination in solution samples;Elemental Analysis is used to determine the Carbon, Hydrogen, and Nitrogen content in solid and viscous samples.Nitrogen Physisorption is a technique used to determine the surface area and pore size of solid materials.

Proper citation: State University of Campinas LIAFQ-IQ Laboratory of Physicochemical Analysis Core Facility (RRID:SCR_027389) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/cancer/research/shared-resources/biorepository/

Core provides collection, annotation, and storage solutions. This Biorepository is also home to a state-wide resource, the Biorepository Alliance of Georgia for Oncology (BRAG-Onc), which functions to collect samples from 6 participating sites across the State to represent the diversity of cancer patients within the State and to enhance cancer research in Georgia.Tissue specimens are fast-frozen in vapor phase liquid nitrogen to preserve their integrity and stored in large cryofreezers at -170 to -190°C. Blood is routinely separated into serum or plasma and buffy coats prior to freezing. Blood derivatives are stored at -70 to -80°C. The freezers are monitored constantly and are connected to an alarm system to ensure that the low temperatures are maintained.

Proper citation: Augusta University Georgia Cancer Center Biorepository Core Facility (RRID:SCR_027271) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/research/core/human-physiology.php

Core provides services including body/bone composition, comprehensive assessments of cardiovascular health (conduit vessel, microvascular, and central arterial stiffness), comprehensive assessment of lung health (spirometry, diffusion, lung clearance index, exhaled NO), and metabolic/exercise testing. Expanded core services in humans include oral glucose tolerance testing and continuous glucose monitoring, 24h ambulatory blood pressure monitoring, and assessments of autonomic nervous system, cognitive function, mitochondrial function, intramuscular fat, and electrocardiograms.

Proper citation: Augusta University Human Physiology Core Facility (RRID:SCR_027270) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/cruk-si-research/laboratory-operations/scientific-services.html

Offers processing fixed tissue for paraffin-embedded histology, cryo-microtomy, cell pellet processing, H+E staining and special histology stains or cellular material supplied. Immunohistochemistry, immunofluorescence and in-situ hybridisation service is available along with the capability to provide digital scanning and analysis. Many other techniques such as provision of tissue microarrays and other staining techniques such as TUNEL can be provided or set-up as required.

Proper citation: Cancer Research UK Scotland Institute Histology Core Facility (RRID:SCR_027306) Copy   

•   Source: SciCrunch Registry

https://emfacility.science.oregonstate.edu/

Core offers negative staining of protein, tissue processing including dehydration, fixation, staining and utra-microtomy, image biological samples at 80 keV on Generation 2 Titan with Rio CMOS side mount camera for low magnification too high magnification shots of cellular structures. Can also rapidly screen grids with Helios STEM in SEM capability. Provides Helios with auto slicenview and fully licensed Avizo for rendering 3D images of cells.

Proper citation: Oregon State University Electron Microscopy Core Facility (RRID:SCR_027308) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/advanced-technologies/deep-phenotyping.html

Core offers comprehensive pathologist-led spatial biology service comprising spatial proteomic, transcriptomic, and multiomic experimental design, including platform and panel selection, assay development, image acquisition, and digital image processing. The facility houses 2x Ventana Discovery Ultra autostainers, 2x 10 x Genomics Xenium platforms, a Lunaphore COMET, an Akoya PhenoImager, an Akoya PhenoCycler, an Olympus VS200 slide scanner and a Visiopharm image analysis suite.

Proper citation: CRUK Scotland Institute Deep Phenotyping Advanced Technology Core Facility (RRID:SCR_027366) Copy   

•   Source: SciCrunch Registry

https://www.iqm.unicamp.br/institucional/infraestrutura/cemuiq/lirmn

Institutional laboratory of Nuclear Magnetic Resonance (NMR) of the Institute of Chemistry of UNICAMP.The Institutional Nuclear Magnetic Resonance Laboratory has 6 NMR spectrometers, two for solids and four for solution probes, with the possibility of analyzing different nuclei.

Proper citation: State University of Campinas Institute of Chemistry Nuclear Magnetic Resonance Laboratory LIRMN-IQ Core Facility (RRID:SCR_027247) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/advanced-technologies/molecular-technology.html

Core provides Next Generation Sequencing (NGS) services and Single Cell services predominantly focussing on single cell RNAseq. Processes samples for variety of cancer associated projects, in both mouse and human derived materials. Offers full end-to-end service, from initial study design and planning, through sample QC, full library preparation, sequencing and data return. Offers range of standard molecular tests covering, plasmid purifications, Sanger sequencing and mycoplasma screening.

Proper citation: Cancer Research UK Scotland Institute Molecular Technology Service Core Facility (RRID:SCR_027368) Copy   

•   Source: SciCrunch Registry

https://wertheim.scripps.ufl.edu/cores-and-technologies/genetic-perturbation-screening/

Core provides guidance in planning and helps with executing gene expression modulation experiments. Currently uses technology based on shRNA for gene knock-down and cDNA libraries for overexpression studies. Core is equipped with genome-wide retroviral shRNA libraries for both human and mouse genomes, Mammalian Gene Collection (MGC) cDNA library, as well as smaller focused sets targeting selected gene families.

Proper citation: Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology Genetic Perturbation Screening Core Facility (RRID:SCR_027255) Copy   

•   Source: SciCrunch Registry

https://research.weill.cornell.edu/core-facilities/human-therapeutic-organoid-core

Facility serves as central facility for human organoid technology to accelerate organoid-based scientific discovery. Provides human pluripotent stem cell (hPSC) derived as well as tissue derived cells and organoids.

Proper citation: Weill Cornell Medicine Human Therapeutic Organoid Core Facility (RRID:SCR_027251) Copy   

•   Source: SciCrunch Registry