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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 08, 2013. A consortium of three facilities whose purpose is to establish, characterize, and distribute novel mutant mouse models with neural and/or behavioral phenotypes, and distribute them to the worldwide research community. Interested scientists are able to obtain information about mouse lines at all three sites in a single unified database. GOALS * Increase genomic and genetic tools for functional gene identification * Provide mice with mutations that alter the nervous system or behavior * Build collaborations between geneticists and neuroscientists The consortium is made up of three mutagenesis and phenotypic screening facilities, focused on identifying alterations in nervous system function and behavior, and established by NIH. They are the Neurogenomics Project at Northwestern University, the Neuroscience Mutagenesis Facility at The Jackson Laboratory, and the Neuromutagenesis Project of the Tennessee Mouse Genome Consortium. The NIH Neurogenomics Project at Northwestern University is directed by Dr. Joseph S. Takahashi, who also acts as the Director of the Neuromice.org consortium. Chemical mutagenesis is used to induce mutations throughout the genome and combined with phenotypic screens to detect mice with mutations. In order to maximize the genomic coverage and recover both dominant and recessive mutations, a dominant G1 screen and a recessive G3 screen are utilized. Phenotypic screens focus on five primary domains: learning and memory, behavioral responses to stress, responses to psychostimulants, circadian rhythmicity, and vision. The Neuroscience Mutagenesis Facility at the Jackson Laboratory is directed by Dr. Wayne N. Frankel. The Neuroscience Mutagenesis Facility is using a three-generation backcross breeding scheme to produce homozygous mutants and will thus recover dominant, semidominant, and recessive mutations. In addition, some mutagenesis will be done in ES cells followed by two generations of breeding. Phenotypic screens focus on identifying mutations affecting: motor function, seizure threshold, hearing, vision, and neurodevelopment. The Neuromutagenesis Project of the Tennessee Mouse Genome Consortium (TMGC) involves researchers throughout the state of Tennessee, under the direction of Dr. Daniel Goldowitz, Ph.D., at the University of Tennessee Health Science Center, Memphis. TMGC also includes researchers at Oak Ridge National Laboratory, Vanderbilt University, Meharry Medical College, University of Tennessee-Knoxville, St. Jude Children's Research Hospital, and the University of Memphis. The Project is using regional mutagenesis, covering regions on chromosomes 10, 14, 15, 19, and X, thus including approximately 15 of the genome in the screened region. Phenotypic screens include: motor and sensory function, learning and memory, neurohistology, aging, alcohol response, abused drug response, visual function, and social behavior. Neuromice.org has stopped taking orders online but mutants are orderable please contact the originating center for availability and pricing details. Live targeted mutant Fragile X model mice are now available for distribution.
Proper citation: neuromice (RRID:SCR_002993) Copy
Lifesharing Tissue Services provides the opportunity to improve and extend lives through the procurement, processing, storage and distribution of human tissue for transplantation and research. Originally established in 1984 to support the Burn Center at UCSD Medical Center, Lifesharing Tissue Services is a non-profit organization serving San Diego and Imperial counties in Southern California. The majority of tissues recovered by Lifesharing Tissue Services stay in this region to enable physicians to provide the best possible care for critically ill patients. Tissue grafting not only reduces pain and speeds recovery, but it also improves a patient''s quality of life. Fully accredited by the American Association of Tissue Banks (AATB) and the Food and Drug Administration (FDA), Lifesharing Tissue Services works to ensure the highest quality of tissue and technical service. Lifesharing is a member of the United Network for Organ Sharing (UNOS).
Proper citation: Lifesharing Tissue Services (RRID:SCR_004325) Copy
http://www.alabamaorgancenter.org
The Alabama Organ Center (AOC) is the federally designated organ procurement organization for the state of Alabama. We work with all of the hospitals in the state to coordinate their donation services. Like all organ procurement organizations, the AOC is a non-profit organization. We provide a variety of services: * Hospital education * Public education * Screening of potential donors * Coordination of the donation process * Family support The AOC is committed to providing a better quality of life for those who require an organ or tissue transplant, while respecting the families who share the gift of life.
Proper citation: Alabama Organ Center (RRID:SCR_004721) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented on August 17, 2021.Biospecimens and support services to advance translational research including a wide range of specimen types, including matched sets of normal and diseased tissue, Formalin-Fixed, Paraffin-Embedded (FFPE), blood, and serum, focusing primarily on cancer. They stock a wide range of sample formats to help meet research goals quickly and on budget. Collections are preformed to be ideal for a wide range of studies including genomic, proteomic, molecular and histologic analysis. ILSbio provides tissue and tissue derivatives that are high quality, cost effective and procured in compliance with current and anticipated regulations. The company obtains its clinical specimens under strict IRB approved protocols with informed consent and the utmost attention to issues of patient safety, anonymity and confidentiality. Clinical and pathological data is available for all specimens. Researchers use the tissue products at all levels of scientific study ranging from large pharma and biotech organizations to small labs and university research facilities. They also participate in wholesale distribution to other bio-banking organizations.
Proper citation: ILSbio (RRID:SCR_004682) Copy
The Louisiana Organ Procurement Agency (LOPA) is the federally-designated organ procurement organization for the State of Louisiana. The agency focuses on educating the medical community and the general public about organ and tissue donation issues, working with families through the donation process, recovering donated organs and tissue, and placing the organs and tissue for transplant. Our mission is to save and enhance lives through organ and tissue donation. We envision a world in which no one suffers due to a lack of donor organs or tissues. LOPA has its main office in Metairie, with regional offices in Lafayette, and Shreveport. Additionally, LOPA has representatives in Baton Rouge, Alexandria, Lake Charles, and Monroe.
Proper citation: Louisiana Organ Procurement Agency - LOPA (RRID:SCR_004442) Copy
Founded in 1977, California Cryobank (CCB) is a full-service sperm bank providing a comprehensive resource for frozen donor sperm, private semen cryopreservation, and specialized reproductive services (including egg and embryo storage and artificial insemination guidance). We are extremely proud of our 30 years of reproductive success. The demand for expert services has grown exponentially as discussion of reproductive challenges has continued to become more mainstream. At California Cryobank we understand that regardless of how much information and education you bring to the process, there can still be significant apprehension accompanying such big steps as sperm donation and donor insemination. CCB''s commitment to making our clients as comfortable as possible is what sets us apart and makes us so much more than just another sperm bank. Our services are entirely patient-centric; from the education that we provide����??answering questions and providing step-by-step timetables that let patients know what to expect in the weeks and months to come from donor sperm selection through insemination����??to the guidance that we offer. Our team is comprised of physicians, lab technicians, genetic counselors, Client Service Consultants, and Donor Matching Consultants. Every facet of our services is completely and expertly led by one of our experienced and compassionate team members. And while our sperm donor program is the foundation of our service, California Cryobank provides a full range of services for our clients including cord blood banking and access to our CCB Sibling Registry.
Proper citation: California Cryobank, Inc. (RRID:SCR_004684) Copy
http://toc.lbg.ac.at/en/research-program/project-tumor-bank
As a basis for the experimental cluster projects, and for further future projects a collection of various biological specimens of cancer patients shall be established. All participating Ludwig Boltzmann Institutes (LBIs) are supplying biological specimens from tumor patients and clinical documentation. At the LBI for Gynecology and Gynecologic Oncology a tumor bank for biological specimens from gynecologic cancer patients already exists. All the procedures for sample processing and storage are well established. Existing equipment for storing tissue specimens at -196 degrees C can be used. Materials from the following malignant diseases are collected: Breast cancer Colorectal cancer Neuroendocrine tumors (NET) (Small cell lung cancer (SCLC) and Carcinoid tumors) Types of biological materials: Tissue (fresh frozen) Bone marrow Blood (serum/plasma/cell fractions) Pleural effusions Ascitic fluids Sputum Bronchial lavage Stool The biological specimens are initially processed at the respective LBIs or at their connected lab facilities. Enrichment of blood samples for disseminated tumor cells is done at the LBI for Gynecology and Gynecologic oncology. Long time storage of all materials is done at appropriate temperatures at the same institution. This LBI also coordinates the logistics. All relevant sample-specific and clinical data are surveyed at the respective LBIs and stored centralized in an on-line data bank in anonymized form, respecting all relevant regulations on data protection and security.
Proper citation: Ludwig Boltzman Tumour Bank (RRID:SCR_004322) Copy
Established in 1970, the University of Miami Tissue Bank (UMTB) is the oldest academic institution of its kind in the United States. UMTB came about and evolved in an effort to provide safe and effective bone and soft tissue grafts to patients long before allograft bone transplantation was widely accepted. UMTB has always been focused on safety and the advancement of knowledge in allograft use. More scientific peer-reviewed articles, book chapters and innovations have come from UMTB either directly or indirectly than from any other organization of its kind. UMTB continues to be a leader in transplantation research and has maintained an impeccable safety record. As the only university-run tissue bank, UMTB works closely with surgeons and basic science investigators to advance the field of bone and soft tissue transplantation. Our scientific endeavors include clinical trials to confirm and improve graft efficacy for oral surgery, orthopedic tumor and spine surgery, and sports injuries. When warranted, we engage commercial entities for these studies. As a multidisciplinary organization of surgeons, pathologists, scientists and technicians, we have safely recovered, processed, distributed and implanted aseptically processed bone, cartilage and soft tissue grafts in thousands of patients. We make extraordinary efforts to ensure aseptic recovery and processing to protect the biologic activity, integrity, bio attributes, and safety of the graft. We believe that the American Association of Tissue Banks (AATB) has adopted appropriate guidelines for Tissue Banking in the United States and the University of Miami is a proud member of this organization.
Proper citation: University of Miami Tissue Bank (RRID:SCR_004560) Copy
The Center for Organ Recovery & Education (CORE) is one of 58 federally designated agencies in the United States known as a not-for-profit organ procurement organization (OPO). CORE is dedicated to promoting donation, education and research for the purpose of saving and improving the quality of life through organ, tissue and corneal transplantation. An innovative, responsive OPO, CORE plays a pivotal role between potential donors and patients awaiting transplantation. In addition to talking with families about the opportunity to donate, CORE coordinates the surgical recovery of organs, tissue and corneas, as well as the computerized matching of donated organs and placement of corneas. In 1995, CORE created the first donor card database in Pennsylvania. In 1996, the organization added tissue recovery and eye banking services to its organ recovery component. It enhanced its line of services by opening an internal laboratory in 1997, where CORE performs the necessary tests to help determine if the organs, tissue and corneas are healthy for transplantation. Since its inception more than 30 years ago, CORE has helped to provide more than 300,000 organs, tissue and corneas for transplantation. The chances for renewed health provided through CORE would not be possible without those who have said yes to donation.
Proper citation: Center for Organ Recovery and Education - CORE (RRID:SCR_004317) Copy
Established in 1987, LifeGift is a not-for-profit organ procurement organization that recovers organs and tissue for individuals needing transplants in 109 Texas counties in North, Southeast and West Texas. Our Role * Help grieving families consider the decision to give the gift of life. Inform families of registered donors of their loved ones����?? wishes to donate. * Coordinate the organ and tissue recovery process with surgeons, other transplant professionals and transplant centers. Collect data for use in transplantation research. * Partner with hospitals to continually develop effective, government-regulated donation systems to help increase the number of donated organs available for transplant. * Educate the public about the need for organ and tissue donation. Serve the African-American, Latino and Asian minority communities with specific educational programs. * Continue to support and maintain contact with donor families following the donation process, facilitating communication between recipients and donor families, if both parties desire.
Proper citation: LifeGift Organ Donation Center (RRID:SCR_004555) Copy
http://allograftinnovations.com/
Allograft Innovations was formed in 2006 to facilitate quality biologic grafts for surgery. We are committed to providing quality tissue to enhance patients'' health, mobility and quality of life nationwide and across the globe. Our goal is to provide the safest, most clinically effective allografts available. The health of tissue recipients is top priority to us, and we take every possible step to ensure safety and integrity during all processes. Allograft Innovations partners with federally designated OPO''s (Organ Procurement Organization), as well as Tissue recovery agencies that comply with all 21 CFR 1270 and 1271 FDA Standards, and have achieved AATB accreditation.
Proper citation: Allograft Innovations, LLC (RRID:SCR_004435) Copy
http://ehs.sph.berkeley.edu/holland/biorepository/
Established in 2004, SPH Biorepository was built to create a centralized facility for many research programs, as well as for new ones; more effective use of the available storage space; development of new database management tools; and quality control of sample processing and banking. While maintaining ultimate control of the samples accumulated in their research projects, PIs will have the assurance of competent handling of their biological samples, reliable access, safe storage, and expert advice from the Biorepository personnel. In the long-term, the Biorepository will provide: * Safe and orderly storage of banked samples * Samples diversification in case of a major disaster *Leverage for additional funding for the new projects Over 145,000 thousands of various biological and environmental samples have been stored and archived through the CHAMACOS, Vitamin, FACES, IBD, and other projects. The Biorepository (Holland - Director) has accumulated substantial expertise in the development of customized databases to barcode and monitor sample location, transfer, and use.
Proper citation: SPH Biorepository (RRID:SCR_004551) Copy
http://www.bionet.umn.edu/tpf/home.html
Procure and distribute human tissue and other biological samples in support of basic, translational, and clinical cancer research at the University of Minnesota. The TPF is a centralized resource with standardized patient consent, sample collection, processing, storage, quality control, distribution, and electronic record maintenance. Since the 1996 inception of the TPF, over 61,000 tissue samples including well-preserved samples of malignant and benign tumors, organ-matched normal tissue, and other types of diseased tissues, have been collected from surgical specimens obtained at the University of Minnesota Medical Center-Fairview (UMMC-F) University Campus. Surgical pathologists are intellectually engaged in TPF functions, providing researchers with specimen-oriented medical consultation to facilitate research productivity. Prior to surgery, TPF personnel identify and consent patients for procurement of tissue, blood, urine, saliva, and ascites fluid. Within the integrated working environment of the surgical pathology laboratory, freshly obtained tissues not needed for diagnosis are selected and provided by pathologists to TPF personnel. Tissue samples are then assigned an independent code and processed. TPF staff can also work with researchers to individualize the procurement of tissues to fit specific research needs.
Proper citation: University of Minnesota Tissue Procurement Facility (RRID:SCR_004270) Copy
https://komentissuebank.iu.edu/
The goals of the Susan G. Komen for the Cure Tissue Bank at the IU Simon Cancer Center are to acquire biomolecule and tissue specimens from the entire continuum of breast development: puberty to menopause and to make these specimens or the digital data derived from them available and accessible to researchers across the globe.
Proper citation: Susan G. Komen Tissue Bank (RRID:SCR_004708) Copy
LifeSource is the non-profit organization dedicated to saving lives through organ and tissue donation in the Upper Midwest. We serve more than 6 million people in communities across Minnesota, North Dakota, South Dakota and portions of western Wisconsin. As the federally-designated organization that manages organ and tissue donation in our region, we are dedicated to working with our hospital and community partners to support donor families, facilitate the donation of organs and tissues to transplant recipients and encourage the people in our communities to register as donors.
Proper citation: LifeSource (RRID:SCR_004702) Copy
http://www.communitytissue.org/
Community Tissue Services (CTS), a not-for-profit tissue bank, was founded in Dayton, Ohio in 1986 as a division of the Community Blood Center. The tissue bank was established to help patients in need of life saving or life enhancing tissue grafts. CTS'' goal is to educate the community of the importance of tissue donation so that families can make informed decisions about the options of donation. CTS serves the public through recovery, processing and distribution of human tissue grafts used for transplantation. Since 1994, CTS has expanded its Dayton, Ohio operations into Texas, Oregon, California, Indiana, Pennsylvania and Tennessee, with over 300 employees nationwide. CTS is an accredited member of the American Association of Tissue Banks and CTS-CTIR is ISO 13485 certified. Strongly committed to providing the highest quality of tissues for transplantation, the tissue bank complies with all federal and state regulations. CTS is currently one of the largest US tissue banks, distributing nearly 10% of the tissue grafts in the United States. CTS is the largest nonprofit provider of skin grafts to surgeons for severe burn patients.
Proper citation: Community Tissue Services - CTS (RRID:SCR_004582) Copy
http://tissuebank.stanford.edu/
The Stanford Tissue Bank was established with seed funding from the Bio-X Program and the Department of Pathology, and currently receives support from the Stanford Cancer Institute. The goal of the Tissue Bank is to facilitate biomedical research using tissues at Stanford, by providing services for the procurement, storage, distribution, and study of tissues. Current Tissue Bank activities and services include collecting and banking freshly-frozen tissue specimens from excess surgical material and from autopsy, providing fresh tissue specimens for viable cell studies, processing and banking blood components, maintaining a tissue database with links to clinicopathological data, performing histological staining and pathological review, and coordinating patient consent and assuring regulatory compliance. As a centralized shared resource, the Tissue Bank adds value through experience, efficiency, standardization, accountability, protection of patient confidentially, and timely completion of research. An oversight committee serves to guide policies, prioritize resources, and review service requests to ensure equitable usage.
Proper citation: Stanford Tissue Bank (RRID:SCR_004615) Copy
http://www.albertahealthservices.ca/services.asp?pid=service&rid=2044
The Southern Alberta Organ and Tissue Donation Program is an integrated donation program for organs, occular tissue and non-occular tissue. These services are provided by the Southern Alberta Organ Donation Program, Lions Eye Bank & the Southern Alberta Tissue Program. This service provides: * coordination of donation, allocation, recovery and distribution of organs for transplantation for Southern Alberta; * recovery, processing, storage and distribution of occular and non-occular tissues for transplantation; * public , professional education and awareness; * research and statistics; * bereavement support.
Proper citation: Southern Alberta Organ and Tissue Donation Program (RRID:SCR_004577) Copy
http://www.georgiahealth.edu/cancer/shared/tumor/index.html
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 31, 2016. The MCG Tumor Tissue and Serum Repository or tumor bank, located in the Department of Pathology, Murphey Pathology Building, was established with support from the Georgia Cancer Coalition (GCC). Its mission is to provide researchers access to high quality annotated specimens, an essential requirement for cancer research. The repository collection includes a variety of specimen types, such as tumor tissue and cells, blood and other biofluids as well as normal specimens used as controls. The quality of all specimens is reviewed by a pathologist, and the information is captured in the tumor bank''s database. An imaging system will be used in the future to capture this information. Human-derived specimens are a very precious resource, and therefore the operations of the tumor bank are overseen by an advisory board, representing GHSU and other stakeholders, to ensure that the specimens are properly utilized and the privacy of specimen donors is protected.
Proper citation: Medical College of Georgia Tumor Bank (RRID:SCR_004336) Copy
http://www.bloodandtissue.org/
The Blood and Tissue Center of Central Texas is a 501(c)(3) not-for-profit organization. Its mission is to safeguard the community''s gifts of blood and tissue with uncompromising quality and excellence in customer service. The Center is licensed by the US Food and Drug Administration, accredited by the American Association of Blood Banks and American Association of Tissue Banks, and is a proud member of America''s Blood Centers. The Blood and Tissue Center today is the exclusive provider and guardian of the community blood supply for more than 37 medical facilities in a ten-county service area of Central Texas. In 2010, over 56,000 whole blood donations and 7,700 apheresis platelet donations were collected. These donations are tested extensively to assure suitability for transfusion and processed into life saving components: red blood cells, plasma, and platelets, which go to help Central Texas patients. The Center works with the Marrow Donor Program of Central and South Texas to increase the number of Central Texans on the National Marrow Donor Registry. The Tissue Services division was established in 1985 due to the increasing demand for allograft tissue. Today, The Tissue Center surgically recovers tissue from approximately 300 donors each year and assists with donor family services. The Tissue Center''s main facility is located in Austin with a satellite office in Corpus Christi.
Proper citation: Blood and Tissue Center of Central Texas (RRID:SCR_004578) Copy
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