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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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DGAP Resource Report Resource Website 1+ mentions |
DGAP (RRID:SCR_003036) | DGAP | database, data or information resource, experimental protocol, narrative resource, resource | Produce resources to unravel the interface between insulin action, insulin resistance and the genetics of type 2 diabetes including an annotated public database, standardized protocols for gene expression and proteomic analysis, and ultimately diabetes-specific and insulin action-specific DNA chips for investigators in the field. The project aims to identify the sets of the genes involved in insulin action and the predisposition to type 2 diabetes, as well as the secondary changes in gene expression that occur in response to the metabolic abnormalities present in diabetes. There are five major and one pilot project involving human and rodent tissues that are designed to: * Create a database of the genes expressed in insulin-responsive tissues, as well as accessible tissues, that are regulated by insulin, insulin resistance and diabetes. * Assess levels and patterns of gene expression in each tissue before and after insulin stimulation in normal and genetically-modified rodents; normal, insulin resistant and diabetic humans, and in cultured and freshly isolated cell models. * Correlate the level and patterns of expression at the mRNA and/or protein level with the genetic and metabolic phenotype of the animal or cell. * Generate genomic sequence from a panel of humans with type 2 diabetes focusing on the genes most highly regulated by insulin and diabetes to determine the range of sequence and expression variation in these genes and the proteins they encode, which might affect the risk of diabetes or insulin resistance. The DGAP project will define: * the normal anatomy of gene expression, i.e. basal levels of expression and response to insulin. * the morbid anatomy of gene expression, i.e., the impact of diabetes on expression patterns and the insulin response. * the extent to which genetic variability might contribute to the alterations in expression or to diabetes itself. | gene, insulin action, predisposition, gene expression, metabolic abnormality, diabetes, insulin resistance, genetics, insulin, genetic variation, proteomics, genomics, affymetrix oligonucleotide array, microarray, protein, genomic sequence, data set |
is related to: NIDDK Information Network (dkNET) has parent organization: Harvard Medical School; Massachusetts; USA has parent organization: Broad Institute has parent organization: Dana-Farber Cancer Institute has parent organization: University of Massachusetts Medical School; Massachusetts; USA has parent organization: University of Southern Denmark; Odense; Denmark |
Type 2 diabetes, Normal, Insulin resistance | NIDDK | PMID:19786482 | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-30414 | SCR_003036 | The Diabetes Genome Anatomy Project, Diabetes Genome Anatomy Project | 2026-02-15 09:18:26 | 9 | ||||
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CCHMC Pediatric Brain Templates Resource Report Resource Website 1+ mentions |
CCHMC Pediatric Brain Templates (RRID:SCR_003276) | Pediatric Brain Templates | atlas, data or information resource, reference atlas, image collection | Brain imaging data collected from a large population of normal, healthy children that have been used to construct pediatric brain templates, which can be used within statistical parametric mapping for spatial normalization, tissue segmentation and visualization of imaging study results. The data has been processed and compiled in various ways to accommodate a wide range of possible research approaches. The templates are made available free of charge to all interested parties for research purposes only. When processing imaging data from children, it is important to take into account the fact that the pediatric brain differs significantly from the adult brain. Therefore, optimized processing requires appropriate reference data be used because adult reference data will introduce a systematic bias into the results. We have shown that, in the in the case of spatial normalization, the amount of non-linear deformation is dramatically less when a pediatric template is used (left, see also HBM 2002; 17:48-60). We could also show that tissue composition is substantially different between adults and children, and more so the younger the children are (right, see also MRM 2003; 50:749-757). We thus believe that the use of pediatric reference data might be more appropriate. | brain, child, human, normal, pediatric, spatial normalization, template, tissue segmentation, visualization, young human, neuroimaging | is related to: SPM | Normal, Healthy | Free, Freely available | nif-0000-01274 | https://jiscmail.ac.uk/cgi-bin/wa-jisc.exe?A2=SPM;981fd215.02 | SCR_003276 | 2026-02-15 09:18:29 | 3 | ||||||
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SHEEP - Stockholm Heart Epidemiology Program Resource Report Resource Website 1+ mentions |
SHEEP - Stockholm Heart Epidemiology Program (RRID:SCR_008905) | KI Biobank - SHEEP | material resource, biomaterial supply resource | DNA from a population-based case-control study designed to investigate causes of myocardial infarction. The study population comprised all Swedish citizens living in the county of Stockholm who were 45 to 70 years of age and free of previously clinically diagnosed MI. Sample types: * DNA Number of sample donors: 2831 (sample collection completed) | heart, epidemiology, cardiac disease, middle adult human, late adult human, aging |
is listed by: One Mind Biospecimen Bank Listing has parent organization: Karolisnka Biobank |
Myocardial infarction, Normal, Aging | nlx_151444 | http://ki.se/ki/jsp/polopoly.jsp?d=29346&a=31574&l=en | SCR_008905 | Stockholm Heart Epidemiology Program | 2026-02-15 09:19:59 | 2 | ||||||
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Framingham Heart Study Resource Report Resource Website 100+ mentions |
Framingham Heart Study (RRID:SCR_008963) | FHS | material resource, biomaterial supply resource | A longitudinal, epidemiologic study to identify the common risk factors or characteristics that contribute to cardiovascular disease by following its development over a long period of time in a large group of participants who had not yet developed overt symptoms or suffered a heart attack or stroke. Since that time the FHS has studied three generations of participants resulting in biological specimens and data from nearly 15,000 participants. Since 1994, two groups from minority populations, including related individuals have been added to the FHS. FHS welcomes proposals from outside investigators for data and biospecimens. The researchers recruited 5,209 men and women between the ages of 30 and 62 from the town of Framingham, Massachusetts, and began the first round of extensive physical examinations and lifestyle interviews that they would later analyze for common patterns related to CVD development. Since 1948, the subjects have continued to return to the study every two years for a detailed medical history, physical examination, and laboratory tests, and in 1971, the Study enrolled a second generation - 5,124 of the original participants'''' adult children and their spouses - to participate in similar examinations. In 1994, the need to establish a new study reflecting a more diverse community of Framingham was recognized, and the first Omni cohort of the Framingham Heart Study was enrolled. In April 2002 the Study entered a new phase, the enrollment of a third generation of participants, the grandchildren of the Original Cohort. In 2003, a second group of Omni participants was enrolled. Over the years, careful monitoring of the Framingham Study population has led to the identification of major CVD risk factors, as well as valuable information on the effects of these factors such as blood pressure, blood triglyceride and cholesterol levels, age, gender, and psychosocial issues. Risk factors for other physiological conditions such as dementia have been and continue to be investigated. In addition, the relationships between physical traits and genetic patterns are being studied. FHS clinical and research data is stored in the dbGaP and NHLBI Repository repositories and may be accessed by application. Please check the following repositories before applying for data through FHS. Investigators seeking data that is not available through dbGaP or BioLINCC or seeking biological specimens may submit a proposal through the FHS web-based research application. The FHS data repository may be accessed through this FHS website, under the For Researchers link, then Description of Data, in order to determine if and how the desired data is stored. Proposals may involve the use of existing data, the collection of new data, either directly from participants or from previously collected samples, images, or other materials (e.g., medical records). The FHS Repository also has biological specimens available for genetic and non-genetic research proposals. Specimens include urine, blood and blood products, as well as DNA. | clinical study, longitudinal study, heart, cardiac, adult human, male, female, risk factor, blood pressure, blood triglyceride, cholesterol level, age, gender, psychosocial, dementia, physical trait, genetic trait, minority, clinical, genotype, phenotype, urine, blood, blood product, dna, FASEB list |
is listed by: One Mind Biospecimen Bank Listing is related to: NCBI database of Genotypes and Phenotypes (dbGap) is related to: Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC) has parent organization: Boston University; Massachusetts; USA |
Cardiovascular disease, Normal, Aging | NHLBI Division of Prevention and Population Sciences | Public / Collaboration preferred: FHS welcomes proposals from outside investigators. Collaboration with FHS investigators is encouraged as it helps to maximize the scientific potential of the unique data. | nlx_151991 | SCR_008963 | 2026-02-15 09:19:55 | 155 | ||||||
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Chernobyl Tissue Bank Resource Report Resource Website 1+ mentions |
Chernobyl Tissue Bank (RRID:SCR_010662) | CTB | material resource, biomaterial supply resource | The CTB (Chernobyl Tissue Bank) is an international cooperation that collects, stores and disseminates biological samples from tumors and normal tissues from patients for whom the aetiology of their disease is known - exposure to radioiodine in childhood following the accident at the Chernobyl power plant. The main objective of this project is to provide a research resource for both ongoing and future studies of the health consequences of the Chernobyl accident. It seeks to maximize the amount of information obtained from small pieces of tumor by providing multiple aliquots of RNA and DNA extracted from well documented pathological specimens to a number of researchers world-wide and to conserve this valuable material for future generations of scientists. It exists to promote collaborative, rather than competitive, research on a limited biological resource. Tissue is collected to an approved standard operating procedure (SOP) and is snap frozen; the presence or absence of tumor is verified by frozen section. A representative paraffin block is also obtained for each case. Where appropriate, we also collect fresh and paraffin-embedded tissue from loco-regional metastases. Currently we do not issue tissue but provide extracted nucleic acid, paraffin sections and sections from tissue microarrays from this material. The project is coordinated from Imperial College, London and works with Institutes in the Russian Federation (the Medical Radiological Research Centre in Obninsk) and Ukraine (the Institute of Endocrinology and Metabolism in Kiev) to support local scientists and clinicians to manage and run a tissue bank for those patients who have developed thyroid tumors following exposure to radiation from the Chernobyl accident. Belarus was also initially included in the project, but is currently suspended for political reasons. |
is listed by: One Mind Biospecimen Bank Listing has parent organization: Imperial College London; London; United Kingdom |
Tumor, Normal, Exposure to radioiodine in childhood following the accident at the Chernobyl power plant | European Union ; Sasakawa Memorial Health Foundation ; NCI |
nlx_70828 | SCR_010662 | 2026-02-15 09:20:19 | 9 |
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