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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://bioconductor.org/packages/release/bioc/html/DESeq.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30,2023. Software for differential gene expression analysis based on the negative binomial distribution. It estimates variance-mean dependence in count data from high-throughput sequencing assays and tests for differential expression.
Proper citation: DESeq (RRID:SCR_000154) Copy
https://github.com/davidliwei/RNASeqReadSimulator
A software tool to generate simulated single-end or paired-end RNA-Seq reads. # It allows users to randomly assign expression levels of transcripts and generate simulated single-end or paired-end RNA-Seq reads. # It is able to generate RNA-Seq reads that have a specified positional bias profile. # It is able to simulate random read errors from sequencing platforms. # The simulator consists of a few simple Python scripts. All scripts are command line driven, allowing users to invoke and design more functions.
Proper citation: RNASeqReadSimulator (RRID:SCR_000270) Copy
http://depts.washington.edu/biowww/
A department within the University of Washington which focuses on both undergraduate and postgraduate education in biochemistry.
Proper citation: UW Department of Biochemistry (RRID:SCR_000149) Copy
http://www.scienceexchange.com/facilities/edgebio
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A contract research organization that provides genomics services such as sequencing, bioinformatics, NGS data analysis and whole exome sequencing. EdgeBio is a CLIA-approved service provider.
Proper citation: EdgeBio (RRID:SCR_000183) Copy
http://www.bioconductor.org/packages/release/bioc/html/MIMOSA.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software for modeling count data using Dirichlet-multinomial and beta-binomial mixtures with applications to single-cell assays.
Proper citation: MIMOSA (RRID:SCR_000184) Copy
https://www.schrodinger.com/glide
Software package which approximates a complete search of the conformational, orientational, and positional space of the ligand in a given receptor. Used in drug development for predicting protein ligand binding modes and ranking ligands via high throughput virtual screening.
Proper citation: Glide (RRID:SCR_000187) Copy
http://acgt.cs.tau.ac.il/modent/
A computational tool that reconstructs gene regulatory networks from high throughput experimental data.
Proper citation: MODENT - A Tool For Reconstructing Gene Regulatory Networks (RRID:SCR_000220) Copy
http://www.ccdc.cam.ac.uk/Solutions/GoldSuite/Pages/GOLD.aspx
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A software for virtual screening and identifying the binding mode of active molecules. It is comprehensively validated, widely used, and allows for high database enrichments. The software utilizes a novel methodology which avoids computationally expensive sequential docking of ligands into multiple protein structures.
Proper citation: GOLD (RRID:SCR_000188) Copy
http://www.unavco.org/data/web-services/documentation/unavco-ws-api/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Web services to access UNAVCO data collection. Adding /gps, /met, /pore, /tilt, and /strain gives the sensor JSON description.
Proper citation: UNAVCO Geodetic Web Services (RRID:SCR_000181) Copy
https://omictools.com/context-likelihood-of-relatedness-tool
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A software that infers regulatory interactions between transcription factors and their targets using a compendium of gene expression profiles.
Proper citation: Context Likelihood of Relatedness (RRID:SCR_000216) Copy
A leading scientific and technology research, development and implementation organization in Africa that undertakes directed research and development for socio-economic growth and improving the quality of life of South African citizens.
Proper citation: Council for Scientific and Industrial Research; Gauteng; South Africa (RRID:SCR_000214) Copy
A global, open, multidisciplinary, non-profit organization that has established standards to support the acquisition, exchange, submission and archive of clinical research data and metadata. Its mission is to develop and support global, platform-independent data standards that enable information system interoperability to improve medical research and related areas of healthcare. CDISC standards are vendor-neutral, platform-independent and freely available via the CDISC website.
Proper citation: Clinical Data Interchange Standards Consortium (RRID:SCR_000219) Copy
https://github.com/vahuynh/dynGENIE3
An algorithm for the inference of gene regulatory networks from expression data.
Proper citation: GENIE3 (RRID:SCR_000217) Copy
http://bonneaulab.bio.nyu.edu/networks.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Algorithm for learning parsimonious regulatory networks from systems biology data sets de novo. Software that utilizes inference algorithm to model genetic regulatory networks.Inferelator 2.0 is scalable framework for reconstruction of dynamic regulatory network models., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Inferelator (RRID:SCR_000218) Copy
http://discover.nci.nih.gov/gominer/GoCommandWebInterface.jsp
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A web program that organizes lists of genes of interest (for example, under- and overexpressed genes from a microarray experiment) for biological interpretation in the context of the Gene Ontology and automates the analysis of multiple microarrays then integrates the results across all of them in exportable output files and visualizations. High-Throughput GoMiner is an enhancement of GoMiner and is implemented with both a command line interface and a web interface. The program can also: efficiently perform automated batch processing of an arbitrary number of microarrays; produce a human- or computer-readable report that rank-orders the multiple microarray results according to the number of significant GO categories; integrate the multiple microarray results by providing organized, global clustered image map visualizations of the relationships of significant GO categories; provide a fast form of false discovery rate multiple comparisons calculation; and provide annotations and visualizations for relating transcription factor binding sites to genes and GO categories.
Proper citation: High-Throughput GoMiner (RRID:SCR_000173) Copy
http://cran.r-project.org/web/packages/c3net/index.html
Software package that allows inferring gene regulatory networks with direct physical interactions from microarray expression data using C3NET.
Proper citation: c3net (RRID:SCR_000212) Copy
The Charles F. and Joanne Knight Alzheimer Disease Research Center (Knight ADRC) supports researchers and our surrounding community in their pursuit of answers that will lead to improved diagnosis and care for persons with Alzheimer disease (AD). The Center is committed to the long-term goal of finding a way to effectively treat and prevent AD. The Knight ADRC facilitates advanced research on the clinical, genetic, neuropathological, neuroanatomical, biomedical, psychosocial, and neuropsychological aspects of Alzheimer disease, as well as other related brain disorders.
Proper citation: Washington University School of Medicine Knight Alzheimers Disease Research Center (RRID:SCR_000210) Copy
An online collaborative editor for academics that use citations and/or formulas. The editor focuses on the content rather than the layout, so that with the same text, it can be published in multiple ways: On a website, as a printed book, or as an ebook.
Proper citation: Fiduswriter (RRID:SCR_000204) Copy
http://www.uniklinikum-saarland.de/einrichtungen/fachrichtungen/humangenetik/software/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A software tool for predicting granzyme B and caspase cleavage sites.
Proper citation: GraBCas (RRID:SCR_000205) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A software package for the prediction of calpain cleavage sites.
Proper citation: GPS-Calpain Cleavage Detector (RRID:SCR_000202) Copy
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