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http://eagle-i.itmat.upenn.edu/i/00000138-e7cd-3f54-eb5b-b63c80000000

Core facility that provides the following services: Immunohistochemistry (IHC) staining service, Tissue processing and sectioning service, Staining service. The Histology and Gene Expression Core Facility provides expert professional services for members of the Cardiovascular Institute. Services for non- Institute investigators are available on a fee-for-service basis as time permits. The Histology and Gene Expression Core offers all histology-related services include tissue processing, embedding, sectioning, staining, immunocytochemistry and InSitu Hybridization.

Proper citation: Penn Histology and Gene Expression Core (RRID:SCR_010017) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-ba97-298d-9cd7-d7e280000000

Core facility that provides the following services: ELISA AND ELISpot assays, Multi-color flow cytometry immunophenotyping and proliferation assays, Luminex multiplex and Cytometric Bead immunological assays, Peripheral blood mononuclear cell isolation, Intraepithelial lymphocyte isolation from intestinal biopsy, Cryopreservation, Immunological assay training. The Human Immunology Core will provide expertise and instrumentation for the analysis of immune function in patients during treatment with anticancer drugs and immunotherapy. The Core will serve as a central facility for incorporating the newest technologies and performing validated immunology assays for phase I/II clinical studies, while also offering expert scientific and technical consultations to users interested in conducting this kind of innovative research.

Proper citation: Penn Human Immunology Core (RRID:SCR_010018) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-5064-ad11-4778-6c3080000000

Core facility that provides the following services: Mass spectrometer access. The Mass Spectrometry Facility is part of the Shared Instrument Facilities of the Department of Chemistry. It provides low and high resolution mass spectra to Penn Chemistry and to other research groups throughout the university community for the determination of elemental composition and purity of a wide variety of compounds. Investigators interested in using the facility are encouraged to call and discuss their project. Usage fees will be quoted at this time. Fees depend upon the instrument involved in the analysis, complexity of the project, training, etc.

Proper citation: Penn Mass Spectrometry Facility (RRID:SCR_010021) Copy   

•   Source: SciCrunch Registry

https://www.bioinformatics.upenn.edu/

Core facility that provides the following services: Desktop sequence analysis tools subscription, Database and web applications support, Genomic-scale sequencing analysis, Sequence analysis application support, Transcript profiling consultation service, Transcript profiling application support, Transcript profiling data analysis, Automating large or repetitive tasks, Web space for biological databases, Bioinformatics/genomics resource identification, and Data storage. The bioinformatics staff of the Penn Molecular Profiling Facility is available to provide experimental design and analytical services to users of the Facility and the basic and biomedical research community. Additional services are provided, including grant support, data management and custom computational projects. This facility provides one-on-one training and hosts instructional workshops. Their goal is to ensure that scientists across the University are able to exploit existing and emerging computational technologies, especially related to their genomics scale datasets.

Proper citation: University of Pennsylvania Molecular Profiling Facility Bioinformatics (RRID:SCR_010022) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013c-48fd-355f-f162-a2b280000000

The Histology and Cellular Localization Core provides training and research support in microscopy, anatomy and histology of chemosensory systems. Core personnel work with Monell researchers to develop and optimize in-house procedures and to establish cutting-edge techniques in histology and cell anatomy. The Core provides centralized services such as tissue sectioning and in situ probe preparation. The Core facility is equipped with cryostats, fluorescence microscopes, confocal microscopes, and a two-photon microscope.

Proper citation: Monell Histology and Cellular Localization Core (RRID:SCR_009958) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013c-48fe-e044-f162-a2b280000000

The Chemosensory Receptor Signaling Core will provide training, advice and research support in molecular biological techniques used to analyze gene expression in cell culture and manipulate the genomes of rodent model organisms. The Core will centralize labor-intensive construct generation common to multiple users and provide users with technical expertise in molecular biological manipulations both in vitro and in vivo. The Core facility has all equipment, reagents, and expertise needed to carry out the following manipulations of RNA, DNA, and protein: RNA isolation, cDNA production, antisense RNA amplification, cloning, subcloning, recombineering, gel electrophoresis, transfection and tissue culture.

Proper citation: Monell Chemosensory Receptor Signaling Core (RRID:SCR_009956) Copy   

•   Source: SciCrunch Registry

http://meharry.eagle-i.net/i/00000135-7dbd-9133-9658-54ab80000000

The Molecular Biology Core Facility at Meharry Medical College is a multi-functional facility that provides to faculty, students, and staff of the college the primary service of DNA sequencing but also provides access to shared equipment housed in a centralized location and facilitates convenient and rapid access to frequently used molecular biological reagents.RRRRR RRRRR The Molecular Biology Core houses a number of shared items of research instrumentation. The core also maintains an Invitrogen Supply Center that stocks many routinely used reagents for molecular biological research. RRRRR RRRRR The major service activities of the Molecular Biology Core are to provide training and technical assistance with the use of shared equipment housed in the core and provide convenient access to molecular biological reagents. Training in the proper use of equipment is provided by the Laboratory Coordinator and also as needed by vendor technical personnel. The core maintains in-house freezers and supply cabinets stocked with many commonly used molecular biological reagents from Invitrogen. In-house reagents are ordered online from Invitrogen and picked up from stocks housed in the core. Invitrogen items not stocked in the core can be ordered online without shipping charges.

Proper citation: Meharry Molecular Biology Core Facility (RRID:SCR_009953) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000013d-1e69-de33-6d01-360380000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. The mission of the Investigator Support and Integration Services (ISIS) program is to facilitate clinical and translational research at OHSU and the Portland VA Medical Center. ISIS works with these institutional partners to streamline study start-up and management processes and related administrative and compliance processes and provide pre-award and regulatory services to investigators. ISIS administers the Human Subjects Protection Program of the Clinical and Translational Research Center (CTRC) to maximize the protection of human subjects involved in OCTRI projects. The OHSU Clinical Trials Office, a unit within ISIS, provides study start-up services and negotiation of contracts for OHSU industry-sponsored clinical trials.

Proper citation: OHSU Investigator Support and Integration Services (RRID:SCR_009951) Copy   

•   Source: SciCrunch Registry

http://meharry.eagle-i.net/i/00000134-a542-2d86-9658-54ab80000000

Core facility that provides the following services: Immunohistochemistry service, Routine histology service, Tissue procurement service. The Human Tissue & Pathology Core provides tissue collection and storage services and access to human tissue, histology services, and specialized equipment. The Core collects human tissues prospectively from routine surgical resections and autopsies for use in basic, translational, and clinical research. Only remnant tissue samples not needed for diagnostic purposes are collected. Tissues are available fresh, snap frozen, or in a variety of fixatives, and normal, neoplastic, and other diseased tissues are available. Histology services include paraffin embedding, paraffin sectioning, automated Hematoxylin and Eosin staining, frozen sectioning, special stains, immunohistochemistry and other specialized processing and sectioning services.

Proper citation: Meharry Human Tissue Acquistion and Pathology Core (RRID:SCR_009952) Copy   

•   Source: SciCrunch Registry

http://meharry.eagle-i.net/i/00000135-2fb3-d3f3-9658-54ab80000000

Core facility that provides the following services: Flow cytometry service. The FACS Core provides a state-of-the-art multi parameter flow cytometry and biosafty level 3 facility on the Meharry Medical College campus. The facility performs flow cytometry analysis, provides expertise in implementing and developing technologies for cell analysis, and provides training to investigators in the use of the instrumentation and in the interpretation of data analysis

Proper citation: Meharry Flow Cytometry and BSL3 Core (RRID:SCR_009950) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7c77-053b-fbab-3b8480000000

Core facility that provides the following services: Tissue processing and paraffin embedding, Cell processing and paraffin embedding, Cryosectioning service, Paraffin-embedded sectioning, Hematoxylin and eosin staining, Immuno-staining (IHC) of tissue sections, Histological staining service. The Cancer Histology Core is a non-profit, research-oriented resource core supported by the Abramson Cancer Center. It offers all histology-related services to all members of the Abramson Cancer Center with high quality, low cost, fast turnout, and easy interaction. Service will be open to all life sciences investigators at Penn, but priority will be given to full members of the Abramson Cancer Center.

Proper citation: Penn Cancer Histology Core (RRID:SCR_010001) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7bcc-1f66-fbab-3b8480000000

Core facility that provides the following services: Antibody screening by ELISA, Cell Culture Training, Production and Purification of Antibodies from Hybridoma Lines, Endotoxin Testing, EBV Transformation, Special media production, Liquid N2 storage, Freezing Cells. Cell Center Services Facility is the service component of the Cell Center, provides training and services in various cell culture and associated procedures including Mycoplasma and Endotoxin testing. The cell culture service includes cell culture at various scales, large scale growth of hybridoma and other cell lines followed by antibody purification by protein G column and the generation of lymphoblastoid cell lines by EBV induced transformation of lymphocytes. In addition, the facility prepares specialized cell culture media, drosophila media, and various molecular biological reagents. Recently cell transfection and selection service has been introduced at the facility.

Proper citation: Penn Cell Center Services Facility (RRID:SCR_010002) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-c63d-d3da-b341-4bb480000000

The purpose of the Vanderbilt Clinical Research Center is to provide the resources needed by clinical and translational investigators to carry out their research in an environment optimized for safety, comfort and convenience of the patient or volunteer, with the facilities and expertise to provide the most advantageous milieu in which to address the investigator''s experimental requirements. This includes outpatient space, inpatient beds, laboratories, equipment and supplies for clinical research by the faculty of Vanderbilt University, Meharry Medical College, and their collaborating investigators. The use of the center is justified on the basis of the quality and significance of the research and the special need for the Center''s facilities.

Proper citation: Vanderbilt Clinical Research Center (RRID:SCR_010170) Copy   

•   Source: SciCrunch Registry

http://tuskegee.eagle-i.net/i/00000136-602c-f62d-ee37-018280000000

THIS RESOURCE IS NO LONGER IN SERVICE, documented January 23, 2019. Core Facility enhances multidisciplinary research infrastructure by providing resources, services and technical support. Solely for Tuskegee University. Primary goal is achieved by providing instrumentation and personnel in two Cores. Core One addresses the need for lab instrumentation and Core Two provides resources in the areas of bioinformatics, computational biology and information technology.

Proper citation: Tuskegee Center for Biomedical Research Shared Instrumentation Core (RRID:SCR_010064) Copy   

•   Source: SciCrunch Registry

http://alaska.eagle-i.net/i/0000012a-2507-871c-a68e-378080000000

Core facility that provides the following services: Sample sequencing service, Sequencing service, Fragment analysis service, Real-time PCR training service. A staffed facility intended to keep UAF at the cutting edge of nucleic acid analysis in evolutionary biology, molecular biology, and wildlife and fisheries management. The Core Facility provides nucleic acid sample analysis, and maintenance and support for molecular instruments (some of which may be too expensive for individual labs to own) for both UAF and outside users.

Proper citation: UAF DNA Core Laboratory (RRID:SCR_010067) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012f-4c48-855d-12ab-077c80000000

Laboratory Support supplies support services for laboratory-based programs at the University of Hawai?i Cancer Center. This resource is operated in order to streamline and make more centralized common laboratory needs.

Proper citation: UH Manoa Laboratory Support Shared Resources (RRID:SCR_010101) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-53ef-0c62-d7c8-cf3780000000

The Nanotechnology and Human Health Core is part of the RCMI program at UT San Antonio. It focuses on the synthesis and characterization of nanomaterials for imaging, labels for bioassays, and active targeting for in vivo or in vitro diagnostics. The Core studies the interaction of nanoparticles with living cells for application in the targeted delivery of drugs, genes, and proteins; tissue engineering scaffolds; artificial organs and implants; and bioimaging and cell labeling. Additionally, the Core supports development of new advanced characterization methods to study biological tissue using nanoparticles and advanced electron microscopy techniques to produce three-dimensional structural information for imaging cell membranes, organelles, and other subcellular structures.

Proper citation: UTSA RCMI Nanotechnology and Human Health Core (RRID:SCR_010150) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-f9db-508b-3c2e-1e5380000000

The Image Analysis Core provides state-of-the-art techniques and software for making use of 3-dimensional images acquired via the RCMI Advanced Imaging Center. Our existing facility, like other centers of its kind, offers investigators the capability to acquire large, high resolution, three dimensional data sets, often as time series. The Core assists investigators in establishing methods for reducing these complex data sets to a form suitable for statistical analysis. The Core draws on the computational resources of The Computational Biology Initiative (CBI) at UTSA to implement standard best practices in image analysis and deliver state of the art image storage, visualization, and quantification to users of the image center, or to users obtaining similar images from equipment in their own laboratories.

Proper citation: UTSA SNRP Image Analysis Core (RRID:SCR_010152) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-5a7e-180a-d7c8-cf3780000000

Core facility that provides the following services: Single crystal growth service, Cambridge Structural Database access. The X-ray diffraction facility, under the supervision and care of Dr. Hadi Arman, offers the chemistry department with the means of X-ray diffraction analysis which is the most reliable route for ascertaining the structure of crystalline materials. The facility maintains a state of the art Rigaku diffractometer. This sealed tube system is equipped with a CCD area detector and can analyze samples at various temperatures. Data processing and analysis are executed on PCs running Microsoft Windows. In addition to the diffractometer, the facility also has access to the electronic Cambridge Structural Database.

Proper citation: UTSA X-ray Crystallography Laboratory (RRID:SCR_010154) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-92f5-c506-07bb-023380000000

The Automation and Informatics Core is responsible for integrating automation and instrumentation with downstream data handling and reporting. Duties of the group include: a) maintaining the laboratory computer network and technology infrastructure, including maintaining network security, performing data backups, managing data access, and trouble-shooting b) database management and information processing, including management of the Laboratory Information Management System (LIMS) c) performing systems analysis and programming as needed for instrument interfaces and integration, as well as extracting, reformatting, uploading, aggregating and/or analyzing data gathered in the course of HTS experiments d) maintaining the automation and robotics, including configuration, calibration, implementation, and trouble-shooting, to ensure maximum uptime/availability and utmost precision and accuracy e) assisting laboratory and scientific personnel with all their informatics needs, including overseeing data exchanges with our collaborators.

Proper citation: Vanderbilt Automation and Informatics Core (RRID:SCR_010159) Copy   

•   Source: SciCrunch Registry