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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
JiffyNet
 
Resource Report
Resource Website
1+ mentions
JiffyNet (RRID:SCR_011954) software application, data analysis service, analysis service resource, software resource, simulation software, production service resource, service resource Web based instant protein network modeler for newly sequenced species. Web server designed to instantly construct genome scale protein networks using protein sequence data. Provides network visualization, analysis pages and solution for instant network modeling of newly sequenced species. protein network, protein, network, genome, sequence, pathway annotation, network visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Yonsei University; Seoul; South Korea
National Research Foundation of Korea ;
Next-Generation BioGreen 21 Program
PMID:23685435 Free, Freely available OMICS_01548, biotools:jiffynet https://bio.tools/jiffynet SCR_011954 2026-02-16 09:48:04 1
NGSmethDB
 
Resource Report
Resource Website
1+ mentions
NGSmethDB (RRID:SCR_012847) NGSmethDB data repository, database, storage service resource, service resource, data or information resource A dedicated database for the storage, browsing and data mining of whole-genome, single-base-pair resolution methylomes. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:20965971 OMICS_01844, biotools:ngsmethdb https://bio.tools/ngsmethdb SCR_012847 NGSmethDB - A database for NGS single-cytosine-resolution DNA methylation data 2026-02-16 09:48:22 9
GeneSigDB
 
Resource Report
Resource Website
10+ mentions
GeneSigDB (RRID:SCR_013275) GeneSigDB web service, data analysis service, analysis service resource, data access protocol, data repository, software resource, storage service resource, database, production service resource, service resource, data or information resource Database of traceable, standardized, annotated gene signatures which have been manually curated from publications that are indexed in PubMed. The Advanced Gene Search will perform a One-tailed Fisher Exact Test (which is equivalent to Hypergeometric Distribution) to test if your gene list is over-represented in any gene signature in GeneSigDB. Gene expression studies typically result in a list of genes (gene signature) which reflect the many biological pathways that are concurrently active. We have created a Gene Signature Data Base (GeneSigDB) of published gene expression signatures or gene sets which we have manually extracted from published literature. GeneSigDB was creating following a thorough search of PubMed using defined set of cancer gene signature search terms. We would be delighted to accept or update your gene signature. Please fill out the form as best you can. We will contact you when we get it and will be happy to work with you to ensure we accurately report your signature. GeneSigDB is capable of providing its functionality through a Java RESTful web service. gene, gene signature, curated gene signature, gene expression, gene expression signature, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Dana-Farber Cancer Institute
has parent organization: Computational Biology and Functional Genomics Laboratory at Harvard
Cancer Genome Research Institute ;
Dana-Farber Cancer Institute ;
Women's Cancers Program ;
Claudia Adams Barr Foundation ;
NLM 1R01 LM010129;
NCI 1U19 CA148065;
NHGRI 1P50 HG004233
PMID:22110038 biotools:genesigdb, nlx_149342 https://bio.tools/genesigdb SCR_013275 Gene Signature Data Base, GeneSigDB - Curated Gene Signatures Database 2026-02-16 09:48:19 24
PlantNATsDB - Plant Natural Antisense Transcripts DataBase
 
Resource Report
Resource Website
1+ mentions
PlantNATsDB - Plant Natural Antisense Transcripts DataBase (RRID:SCR_013278) PlantNATsDB data analysis service, analysis service resource, database, production service resource, service resource, data or information resource Natural Antisense Transcripts (NATs), a kind of regulatory RNAs, occur prevalently in plant genomes and play significant roles in physiological and/or pathological processes. PlantNATsDB (Plant Natural Antisense Transcripts DataBase) is a platform for annotating and discovering NATs by integrating various data sources involving approximately 2 million NAT pairs in 69 plant species. PlantNATsDB also provides an integrative, interactive and information-rich web graphical interface to display multidimensional data, and facilitate plant research community and the discovery of functional NATs. GO annotation and high-throughput small RNA sequencing data currently available were integrated to investigate the biological function of NATs. A ''''Gene Set Analysis'''' module based on GO annotation was designed to dig out the statistical significantly overrepresented GO categories from the specific NAT network. PlantNATsDB is currently the most comprehensive resource of NATs in the plant kingdom, which can serve as a reference database to investigate the regulatory function of NATs. natural antisense transcript, annotation, high-throughput, small rna sequencing, function, regulatory function, predict, sequence, small rna, blast, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: Gene Expression Omnibus
has parent organization: Zhejiang University; Zhejiang; China
National Natural Sciences Foundation of China 30971743;
National Natural Sciences Foundation of China 31050110121;
National Natural Sciences Foundation of China 31071659;
Ministry of Science and Technology of China 2009DFA32030;
Program for New Century Excellent Talents in University of China NCET-07-0740;
Huazhong Agricultural University Scientific and Technological Self-innovation Foundation 2010SC07
PMID:22058132 Free nlx_151492, biotools:plantnatsdb https://bio.tools/plantnatsdb SCR_013278 Plant Natural Antisense Transcripts DataBase 2026-02-16 09:48:26 9
TopHat
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
TopHat (RRID:SCR_013035) software application, data processing software, sequence analysis software, data analysis software, image analysis software, software resource, alignment software Software tool for fast and high throughput alignment of shotgun cDNA sequencing reads generated by transcriptomics technologies. Fast splice junction mapper for RNA-Seq reads. Aligns RNA-Seq reads to mammalian-sized genomes using ultra high-throughput short read aligner Bowtie, and then analyzes mapping results to identify splice junctions between exons.TopHat2 is accurate alignment of transcriptomes in presence of insertions, deletions and gene fusions. align, RNA-Seq, read, cDNA, sequencing, transcriptomics, fast, splice, junction, mapper, exon, analysis, bio.tools uses: Bowtie
is used by: CIRCexplorer
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: HISAT2
has parent organization: University of Maryland; Maryland; USA
has parent organization: University of California at Berkeley; Berkeley; USA
has parent organization: Johns Hopkins University; Maryland; USA
has parent organization: University of Washington; Seattle; USA
works with: GeneScissors
NHGRI R01 HG006102;
NHGRI R01 HG006677
PMID:23618408
PMID:19289445
DOI:10.1093/bioinformatics/btp120
Free, Available for download, Freely available biotools:tophat, OMICS_01257 https://github.com/infphilo/tophat
https://bio.tools/tophat
https://sources.debian.org/src/tophat/
http://tophat.cbcb.umd.edu/ SCR_013035 tophat, TopHat1, Tophat2 2026-02-16 09:48:24 9575
MitoBreak
 
Resource Report
Resource Website
10+ mentions
MitoBreak (RRID:SCR_012949) MitoBreak data repository, database, storage service resource, service resource, data or information resource Database with curated datasets of mitochondrial DNA (mtDNA) rearrangements. Users may submit new mtDNA rearrangements. mitochondrial dna rearrangement, mitochondrial dna, deletion, duplication, linear, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24170808 Free, The community can contribute to this resource biotools:mitobreak, OMICS_01640 https://bio.tools/mitobreak SCR_012949 2026-02-16 09:48:19 10
minfi
 
Resource Report
Resource Website
100+ mentions
minfi (RRID:SCR_012830) minfi software application, data processing software, data visualization software, data analysis software, software resource Software tools for analyzing and visualizing Illumina''s 450k array data. Illumina, array data, Analyze Illumina Infinium DNA methylation arrays, DNA methylation array, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: SWAN
has parent organization: Bioconductor
PMID:28035024 Free, Available for download, Freely available biotools:minfi, OMICS_00799, BioTools:minfi https://bio.tools/minfi
https://bio.tools/minfi
https://bio.tools/minfi
SCR_012830 2026-02-16 09:48:18 390
IMGT - the international ImMunoGeneTics information system
 
Resource Report
Resource Website
500+ mentions
IMGT - the international ImMunoGeneTics information system (RRID:SCR_012780) IMGT data analysis service, analysis service resource, database, topical portal, portal, production service resource, service resource, data or information resource A high-quality integrated knowledge resource specialized in the immunoglobulins (IG) or antibodies, T cell receptors (TR), major histocompatibility complex (MHC) of human and other vertebrate species, and in the immunoglobulin superfamily (IgSF), MHC superfamily (MhcSF) and related proteins of the immune system (RPI) of vertebrates and invertebrates, serving as the global reference in immunogenetics and immunoinformatics. IMGT provides a common access to sequence, genome and structure Immunogenetics data, based on the concepts of IMGT-ONTOLOGY and on the IMGT Scientific chart rules. IMGT works in close collaboration with EBI (Europe), DDBJ (Japan) and NCBI (USA). IMGT consists of sequence databases, genome database, structure database, and monoclonal antibodies database, Web resources and interactive tools. immunogenetics, immunoinformatics, immunoglobulin, antibody, t cell receptor, major histocompatibility complex, immunoglobulin superfamily, major histocompatibility complex superfamily, protein, immune system, sequence, genome, structure, monoclonal antibody, gold standard, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: IMGT Repertoire
has parent organization: Montpellier 2 University; Montpellier; France
is parent organization of: IMGT/LIGM-DB
is parent organization of: IMGT/GENE-DB
is parent organization of: IMGT-ONTOLOGY
is parent organization of: IMGT/V-QUEST
is parent organization of: IMGT/HLA
CNRS ;
MESR ;
Reseau National des Genopoles ;
Region Languedoc-Roussillon ;
European Union BIOMED1 BIOCT930038;
European Union Biotechnology BIOTECH2 BIO4CT960037;
European Union 5th PCRDT Quality of Life and Management of Living Resources QLG2-2000-01287;
Agence Nationale de la recherche ANR BIOSYS06_135457;
EU ImmunoGrid IST-028069
PMID:18978023 nif-0000-03011, biotools:imgt https://bio.tools/imgt http://imgt.cines.fr SCR_012780 ImMunoGeneTics Information System, IMGT/LIGM, ImMunoGeneTics 2026-02-16 09:48:29 746
Dali Server
 
Resource Report
Resource Website
500+ mentions
Dali Server (RRID:SCR_013433) data analysis service, analysis service resource, software resource, production service resource, service resource Network service for comparing protein structures in 3D. You submit the coordinates of a query protein structure and Dali compares them against those in the Protein Data Bank (PDB). You receive an email notification when the search has finished. In favourable cases, comparing 3D structures may reveal biologically interesting similarities that are not detectable by comparing sequences. Requests can also be submitted by e-mail to dali-server at helsinki dot fi. The body of the e-mail message must contain atomic coordinates in PDB format. If you want to know the structural neighbours of a protein already in the Protein Data Bank (PDB), you can find them in the Dali Database. If you want to superimpose two particular structures, you can do it in the pairwise DaliLite server. Academic users may download the DaliLite program for local use. Protein structure comparison server, protein structure, comparison server, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: University of Helsinki; Helsinki; Finland
PMID:20457744 Free, Freely available biotools:dali https://bio.tools/dali SCR_013433 Dali 2026-02-16 09:48:27 509
clustergrammer
 
Resource Report
Resource Website
10+ mentions
clustergrammer (RRID:SCR_015681) data visualization tool, software tool Clustergrammer is a web-based tool for visualizing and analyzing high-dimensional data as interactive and shareable hierarchically clustered heatmaps. Clustergrammer enables intuitive exploration of high-dimensional data and has several optional biology-specific features. bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1038/sdata.2017.151 biotools:clustergrammer https://bio.tools/clustergrammer SCR_015681 2026-02-16 09:48:51 41
GenePattern Notebook
 
Resource Report
Resource Website
1+ mentions
GenePattern Notebook (RRID:SCR_015699) software application, software resource, systems interoperability software, electronic laboratory notebook, web application Interactive analysis notebook environment that streamlines genomics research by interleaving text, multimedia, and executable code into unified, sharable, reproducible “research narratives.” It integrates the dynamic capabilities of notebook systems with an investigator-focused, simple interface that provides access to hundreds of genomic tools without the need to write code. gene, genomics research, research narrative, notebook system, analysis notebook, bio.tools is listed by: bio.tools
is listed by: Debian
is affiliated with: GenePattern
NIGMS R01-GM074024;
NCI U24-CA194107
PMID:28822753 Open Source, Free, Available for download, Account required biotools:GenePattern_notebook https://bio.tools/GenePattern_notebook SCR_015699 GenePattern Notebook environment 2026-02-16 09:48:56 3
HISAT2
 
Resource Report
Resource Website
10000+ mentions
HISAT2 (RRID:SCR_015530) software application, data processing software, sequence analysis software, data analysis software, source code, software resource Graph-based alignment of next generation sequencing reads to a population of genomes. alignment program, mapping reads, population genomics, human genome, bio.tools is used by: Fcirc
is listed by: Debian
is listed by: bio.tools
is related to: TopHat
has parent organization: Johns Hopkins University; Maryland; USA
is required by: SL-quant
is hosted by: GitHub
NLM R01-LM06845;
NIGMS R01-GM083873;
NSF CCF-0347992
PMID:25751142
DOI:10.1038/s41587-019-0201-4
Available for download OMICS_07225, biotools:hisat2 https://github.com/infphilo/hisat2
https://bio.tools/hisat2
https://sources.debian.org/src/hisat2/
SCR_015530 HISAT 2026-02-16 09:48:55 17595
Hybrid-denovo
 
Resource Report
Resource Website
1+ mentions
Hybrid-denovo (RRID:SCR_015866) software application, data processing software, sequence analysis software, data analysis software, software resource Software for a de novo OTU-picking pipeline integrating single- and paired-end 16S sequence tags. It is designed to take Illumina paired-end sequencing reads as input and output the OTU BIOM table, together with their representative sequences and a phylogenetic tree of OTUs. hybrid-denovo, 16S rRNA, microbiota pipeline, single-end, paired-end, illumina read, de novo, otu-picking pipeline, phylogenetic tree, python, bio.tools is listed by: bio.tools
is listed by: Debian
biotools:hybrid-denovo https://bio.tools/hybrid-denovo SCR_015866 2026-02-16 09:48:53 3
NiftyPET
 
Resource Report
Resource Website
1+ mentions
NiftyPET (RRID:SCR_015873) software application, data processing software, software toolkit, data visualization software, image analysis software, software resource, source code Python software package that offers quantitative PET image reconstruction and analysis with high accuracy and precision. It is written in CUDA C and embedded in Python C extensions. python, cuda c, python c, pet, image reconstruction, image analysis, bio.tools uses: CMake
is listed by: Debian
is listed by: bio.tools
DOI:10.1007/s12021-017-9352-y Free, Available for download, Runs on Windows, Runs on Linux biotools:niftypet https://bio.tools/niftypet SCR_015873 2026-02-16 09:48:57 6
oligo
 
Resource Report
Resource Website
1000+ mentions
oligo (RRID:SCR_015729) software application, data processing software, data analysis software, source code, software resource Software package to analyze oligonucleotide arrays (expression/SNP/tiling/exon) at probe-level. It currently supports Affymetrix (CEL files) and NimbleGen arrays (XYS files). oligonucleotide, microarray gene expression, r, oligonucleotide array, snp, gene expression, probe-level, affymetrix array, cel file, and nimblegen array, xys file, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
CAPES (Coordenação de Aprimoramento Pessoal de Nível Superior) ;
NCRR R01RR021967;
NHGRI P41HG004059
PMID:20688976 Free, Available for download, Runs on Mac OS, Runs on Windows biotools:oligo https://bio.tools/oligo SCR_015729 oligo package 2026-02-16 09:48:56 1749
BSVF
 
Resource Report
Resource Website
1+ mentions
BSVF (RRID:SCR_015727) BSVF software application, data processing software, sequence analysis software, data analysis software, source code, software resource Software code for bisulfite sequencing virus integration. This finder is for directional libraries only and does not support PBAT and indirectional libraries. virus integration, sequencing analysis, virus assembly, integration, bisulfite, bio.tools is listed by: bio.tools
is listed by: Debian
Open source biotools:bs-virus-finder https://bio.tools/bs-virus-finder SCR_015727 BSVF: Bisulfite Sequencing Virus integration Finder, Bisulfite Sequencing Virus integration Finder 2026-02-16 09:48:52 1
andi
 
Resource Report
Resource Website
10+ mentions
andi (RRID:SCR_015971) software application, data processing software, algorithm resource, image analysis software, software resource, alignment software Software tool for rapidly computing and estimating evolutionary distance between closely related genomes. Because andi does not compute full alignments it scales even up to thousands of bacterial genomes. algorithm, computing, estimate, analysis, genome, alignment, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Deutsche Forschungsgemeinschaft Pf672/3-1 PMID:25504847 Free, Freely available, Available for download OMICS_09287, biotools:andi https://bio.tools/andi
https://sources.debian.org/src/andi/
SCR_015971 2026-02-16 09:48:55 41
larvalign
 
Resource Report
Resource Website
1+ mentions
larvalign (RRID:SCR_015815) software application, data processing software, software toolkit, sequence analysis software, data analysis software, data set, software resource, data or information resource Software package including computational methods for aligning gene expression patterns from the larval brain of Drosophila melanogaster. Its method includes evaluation of the registration framework involved in template generation and mapping. drosophila melanogaster, computational method, gene expression, alignment, larval brain, larvae, template generation, mapping, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download biotools:larvalign https://bio.tools/larvalign SCR_015815 2026-02-16 09:48:53 1
TreeDyn
 
Resource Report
Resource Website
100+ mentions
TreeDyn (RRID:SCR_015946) software application, data processing software, data visualization software, software resource Visualization software that links unique leaf labels to lists of variables/values pairs of annotations (meta-information), independently of the tree topologies, remaining fully compatible with the basic newick format. These relationships are used by dynamic graphics operators, information visualization methods like Projection, Localization, Labelization, Reflection allowing an interaction from annotations to trees, from trees to annotations and from trees to trees through annotations., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. tree, variable, annotation, metainfo, newick, topology, graphic, operator, projection, localization, reflection, leaf, label, bio.tools is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE biotools:treedyn https://bio.tools/treedyn SCR_015946 2026-02-16 09:48:55 355
SC3
 
Resource Report
Resource Website
10+ mentions
SC3 (RRID:SCR_015953) software application, data processing software, sequence analysis software, data analysis software, software resource Software tool for the unsupervised clustering of cells from single cell RNA-Seq experiments. SC3 is capable of identifying subclones from the transcriptomes of neoplastic cells collected from patients. scRNA-seq, interactive, cluster, clustering, cell, single, rna, rnaseq, bio.tools is listed by: Debian
is listed by: bio.tools
Wellcome Trust 104710/Z/14/Z;
Belgian Network DYSCO ;
FRS-FNRS ;
Belgian State Science Policy Office ;
ARC (Action de Recherche Concerte) ;
Wallonia-Brussels Federation ;
EPSRC EP/N014529/1;
Sanger Institute ;
University of Edinburgh ;
Bloodwise 13003;
MRC ;
Kay Kendall Leukaemia Fund ;
Cambridge NIHR Biomedical Research Center ;
Cambridge Experimental Cancer Medicine Centre ;
Leukemia and Lymphoma Society of America 07037
PMID:28346451 Free, Available for download biotools:sc3 https://bio.tools/sc3 SCR_015953 SC3 package, Single-Cell Consensus Clustering 2026-02-16 09:48:58 20

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