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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Penn Small Animal Imaging Facility: Ultrasound Sub-Core
 
Resource Report
Resource Website
Penn Small Animal Imaging Facility: Ultrasound Sub-Core (RRID:SCR_010034) service resource, access service resource, core facility Core facility that provides the following services: Contrast enhanced sonography, Quantitative analysis of images, Small animal ultrasound imaging, Blood flow velocity measurement, Tissue motion measurement. The Ultrasound Sub-Core of the SAIF offers an array of research services for pre-clinical research including quantitative image analysis and consultation. Our state-of-the-art ultrasound scanners are available as a resource for conducting your research studies. This rich resource for ultrasound imaging is available at nominal hourly fees for various categories of study. Ultrasound Research Services provides services to a host of groups working on diverse projects such as the measurement of angiogenesis, vascularity, tissue elasticity, the effects of various pharmaceuticals on these measures and more. Such research encompasses a variety of clinical areas including radiology, oncology, cardiology, gynecology, and hematology, among others. ultrasonography, image analysis, doppler velocity measurements is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156505 SCR_010034 2026-02-17 10:01:22 0
OHSU Massively Parallel Sequencing Shared Resource Core Facility
 
Resource Report
Resource Website
1+ mentions
OHSU Massively Parallel Sequencing Shared Resource Core Facility (RRID:SCR_009984) MPSSR service resource, access service resource, core facility As of January 1, 2024, the Integrated Genomics Laboratory is one shared resource comprising the former Massively Parallel Sequencing Shared Resource, the Gene Profiling Shared Resource, and the DNA Services Core. Please be aware that the reorganization is an ongoing process, particularly regarding our iLab integration.Provides RNA-sequencing for gene expression analysis, DNA resequencing for single nucleotide polymorphism discovery, DNA resequencing for copy number variation discovery, ChiP-sequencing for promoter analysis, DNA methylation analysis, De novo sequencing for unique genomes, Sequence capture service. Offers sequencing including genome resequencing, transcriptome analysis, miRNA analysis, and prometer analysis via ChIP-seq. RNA-sequencing for gene expression analysis, DNA resequencing for single nucleotide polymorphism discovery, DNA resequencing for copy number variation discovery, ChiP-sequencing for promoter analysis, DNA methylation analysis, De novo sequencing for unique genomes, USEDit is listed by: Eagle I
is related to: USEDit
is related to: Oregon Health and Science University Integrated Genomics Laboratory Core Facility
has parent organization: Oregon Health and Science University; Oregon; USA
nlx_156453, SCR_018868 http://ohsu.eagle-i.net/i/0000012b-5a48-0b10-62b8-f47280000000 SCR_009984 OHSU Massively Parallel Sequencing Shared Resource 2026-02-17 10:01:40 8
OHSU Methamphetamine Abuse Research Center Animal Core Component
 
Resource Report
Resource Website
OHSU Methamphetamine Abuse Research Center Animal Core Component (RRID:SCR_009985) service resource, access service resource, core facility THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6,2022. Core facility that provides the following services: Mouse breeding service, Behavioral testing procedures service, Mouse breeding. Three of the MARC''s research components (5, 6, and 8) include experiments with lines of mice bred to have special genetic traits. The animal core supports these components by purchasing, testing, breeding, maintaining, and distributing these animals within the center. The core will breed special mouse lines F1 and F2 that are descendents of C57BL/6J (B6) and DBA/2J (D2) inbred strains. For Components 5 and 6, the animal core will also produce independent sets of replicated mouse lines selected for high and low tendencies toward methamphetamine drinking and for high and low methamphetamine-induced sensitization. In addition, the core is developing new behavioral-testing procedures and maintaining a database that will track individual animals and post their trait data for all MARC investigators to utilize. mouse breeding, behavioral assay is listed by: Eagle I
has parent organization: Oregon Health and Science University; Oregon; USA
THIS RESOURCE IS NO LONGER IN SERVICE nlx_156454 SCR_009985 2026-02-17 10:01:21 0
OHSU In Vivo Optical Imaging Center
 
Resource Report
Resource Website
OHSU In Vivo Optical Imaging Center (RRID:SCR_009982) service resource, access service resource, core facility THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility that provides the following services: Use of IOIC facility, In vivo optical imaging training service. The IOIC is located in Cardiac Imaging Laboratory on the first floor of the Biomedical Research Building (BRB). The laboratory was established through a Shared Instrument Grant (PI: Michael Deininger) but is maintained through user fees. The core facility includes the IVIS Spectrum optical imaging camera housed in a light-tight housing, rat and mouse imaging platforms for multi-subject simultaneous acquisition, an integrated inhaled anesthesia system, and advanced analysis software. A key component of the IOIC is the ability to operate either independently or under the guidance and supervision of core personnel. Independent use of the system requires that investigators undergo training that is offered every 2 months or on an ad hoc basis. All analysis will be charged on an hourly basis and is graduated according to the level of service (independent or supervised). digital imaging is listed by: Eagle I
has parent organization: Oregon Health and Science University; Oregon; USA
THIS RESOURCE IS NO LONGER IN SERVICE nlx_156449 SCR_009982 2026-02-17 10:01:33 0
Penn Diabetes Research Center Transgenic and Chimeric Mouse Core Facility
 
Resource Report
Resource Website
Penn Diabetes Research Center Transgenic and Chimeric Mouse Core Facility (RRID:SCR_010036) service resource, access service resource, core facility Mouse core which generates transgenic and gene-targeted mouse lines for diabetes research. transgenic mice, transgenic mouse, diabetes mouse is listed by: Eagle I
is listed by: NIDDK Information Network (dkNET)
has parent organization: University of Pennsylvania; Philadelphia; USA
has parent organization: Penn Diabetes Research Center
is organization facet of: Penn Diabetes Research Center
Diabetes Available to the research community, Fee for service nlx_156507 SCR_010036 Penn Diabetes Research Center Transgenic and Chimeric Mouse Core 2026-02-17 10:01:35 0
UH Manoa RCMI Magnetic Resonance Image Processing Core
 
Resource Report
Resource Website
UH Manoa RCMI Magnetic Resonance Image Processing Core (RRID:SCR_010037) service resource, access service resource, core facility Core facility that provides the following services: Brain MRI service. Researchers in the Neuroscience and Magnetic Resonance Research Program are using a research dedicated 3-Tesla scanner to study the human brain and brain diseases. Facilities: The Magnetic Resonance (MR) Processing Core serves the needs of researchers in the MR Research Facility at Queen''s Hospital. Specifically, the MR Image Processing Core provides image processing support, infrastructure development, methodological development and training; expertise is available. magnetic resonance imaging is listed by: Eagle I
has parent organization: University of Hawaii at Manoa
nlx_156581 SCR_010037 2026-02-17 10:01:42 0
OHSU Immunology Support Core Cellular Immunology Unit
 
Resource Report
Resource Website
OHSU Immunology Support Core Cellular Immunology Unit (RRID:SCR_009980) service resource, access service resource, core facility THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6,2022. Core facility that provides the following services: Immunological study design and implementation, Flow cytometry assays service, High-throughput analysis service, Economies-of-scale reagent purchasing, Flow cytometry sorting service. The CIU offers all the study organization and technical expertise developed at the (Louis) Picker Lab to researchers whose questions require obtaining and processing monkey immunological samples, and/or utilizing cytometry to assay phenotype of CFC/ICS information. The CIU was originally developed as part of the Bill & Melinda Gates foundation CAVD (Collaboration for AIDS Vaccine Discovery) consortium. flow cytometry assay, cell proliferation assay, multiplex bead assay, cell phenotyping, fluorescence activated cell sorting (facs), antibody production is listed by: Eagle I
has parent organization: Oregon Health and Science University; Oregon; USA
THIS RESOURCE IS NO LONGER IN SERVICE nlx_156447 SCR_009980 2026-02-17 10:01:21 0
Penn/CHOP CTRC Research Nurse Core
 
Resource Report
Resource Website
Penn/CHOP CTRC Research Nurse Core (RRID:SCR_010040) service resource, access service resource, core facility Core facility that provides the following services: Outpatient study facility access, iDXA scan service, Research specimen processing, Research specimen storage, NIH/Industry clinical trial support, Pharmacy laboratory access, Adipose biopsy, Patient assessment and monitoring, Metabolic testing service, Phlebotomy, Support for bone marrow biopsies. The Clinical and Translational Research Center (CTRC) has two main locations as well as satellite locations. The protocols cover a wide variety of research areas including: HIV, sleep disorders, cholesterol, obesity, diabetes, various cancers, arthritis, hypertension, renal disease, short bowel syndrome, and neonatal and surgical studies as well as new treatments for various diseases. The CTRCs service over 1200 inpatients and over 6000 outpatients a year. Research subjects range from premature infants to the elderly, with the majority of adults being seen at HUP. HUP Unit - Dulles Building: * 8 bed inpatient * 8 chair and 2 bed outpatient unit * metabolic kitchen * Scatterbed nursing services throughout hospital units including the ICUs, ED and operating rooms UPPMC Unit ? 1st Fl Mutch Building: * 18 outpatient treatment beds * metabolic kitchen CHOP Units: * 4 bed inpatient unit - 5 West Main * outpatient unit with 2 treatment rooms, 4 treatment chairs and a consultation room - Main 7 * Scatterbed nursing services in Newborn Nursery - Ravdin Building The nurse manager should be contacted prior to submitting a new protocol submission to the CTRC and discussions should continue throughout the start-up process. clinical assay, dual energy x-ray absorptiometry, blood serum isolation, blood plasma isolation, biological sample processing, clinical trial technique, fat biopsy, clinical monitoring, subcutaneous injection, intravenous injection, glucose tolerance test, blood sampling, biopsy is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156512 SCR_010040 2026-02-17 10:01:35 0
UH Manoa RCMI Microarray Core Facility
 
Resource Report
Resource Website
UH Manoa RCMI Microarray Core Facility (RRID:SCR_010042) service resource, access service resource, core facility Core facility that provides the following services: Gene expression analysis service, SNP analysis service, Genotyping service. We conduct microarray-related experiments, including developing chips for pathogen discovery, evaluating RNA quality and test chips, processing RNA specimens, hybridizing microarray chips, scanning microarray chips and providing raw data for analysis. gene expression analysis assay, single-nucleotide polymorphism analysis, genotyping assay is listed by: Eagle I
has parent organization: University of Hawaii at Manoa
nlx_156582 SCR_010042 2026-02-17 10:01:22 0
Penn/CHOP CTRC Study Design and Biostatistics Core
 
Resource Report
Resource Website
Penn/CHOP CTRC Study Design and Biostatistics Core (RRID:SCR_010043) service resource, access service resource, core facility Core facility that provides the following services: Data management assistance, Biostatistical analysis assistance. The Study Design and Biostatistics (SDAB) Core works closely with existing resources to provide targeted study design and biostatistics support to ITMAT/CTSA investigators. The Core serves as a direct provider of services, including protocol review, study design, proposal development, and performance of simple to potentially substantial complex analyses. SDAB integrates the support available with the HUP and CHOP Clinical and Translational Research Centers (CTRCs), the expertise and resources of faculty in the Center for Clinical Epidemiology and Biostatistics / Department of Biostatistics and Epidemiology (CCEB/DBE), the Biostatistics Analysis Center (BAC), and the Biostatistics and Data Management Core (BDMC) at CHOP. computer privacy management, database development, data management, data analysis, computational modeling technique is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156514 SCR_010043 2026-02-17 10:01:39 0
Penn/CHOP CTRC Translational Core Laboratories
 
Resource Report
Resource Website
Penn/CHOP CTRC Translational Core Laboratories (RRID:SCR_010044) service resource, access service resource, core facility Core facility that provides the following services: Cell culture and tissue services, DNA isolation service, Cell culture and tissue services, Epstein Barr Virus (EBV) lymphocyte transformation service, Cell culture and tissue services, Fibroblast culture and cryopreservation service, Cell culture and tissue services, Specialized cell isolation service, Molecular biology services, microsatellite haplotyping service, Molecular biology services, mutation analysis service, Molecular biology services, Restriction fragment analysis service, Molecular biology services, RNA services, Molecular biology services, SNP genotyping service, Specimen Collection, Processing, and Point-of-Care services, Bedside tests by Bayer Rapid Point 400, Specimen Collection, Processing, and Point-of-Care services; Collection, processing and storage of specimens, Specimen Collection, Processing, and Point-of-Care services, Packaging and shipping of samples. The Translational Core Laboratory consists of the Specimen Collection, Processing and Point of Care, Biochemistry, Cell Culture/DNA Isolation, and Molecular Biology core laboratories. Laboratory testing is integrated across Penn and CHOP, and TCL services are provided at multiple physical locations at both Penn and CHOP. Penn location: first floor Smilow Center for Translational Research CHOP location: 804 Abramson Research Center (ARC) dna extraction, genetic transformation, ebv transformation, cryopreservation, maintaining cell culture, biological sample processing, microsatellite analysis, heteroduplex mutation detection, dna sequencing, dna cleavage, restriction analysis, transcription profiling assay, reverse transcribed polymerase chain reaction, real-time pcr, snp interrogation genotyping, clinical assay, blood sampling, material storage, material sampling process is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156515 SCR_010044 2026-02-17 10:01:35 0
Penn/CHOP Office of Human Subject Recruitment and Protection
 
Resource Report
Resource Website
Penn/CHOP Office of Human Subject Recruitment and Protection (RRID:SCR_010046) service resource, access service resource, core facility Core facility that provides the following services: Clinical study support services. The Office of Human Subject Recruitment and Protection (OHSRP) provides consultation and guidance to the Penn research community on all issues related to adult and pediatric human subjects being seen through the CTRC facilities, including recruitment and protection. The role of the OHSRP is to champion the mission of the feasible, safe and ethical conduct of human subject research within the CTRC. The original Research Subject Advocate (RSA) was a position mandated by the National Center for Research Resources under the NIH and was defined in order to ensure that research was being conducted in ways that did not increase the risk associated with conducting studies. In April 2008, the CTSA Consortium Steering Committee approved and endorsed best practices, which serve to define the mission, scope, and model for research advocacy within the CTSA consortium. The OHSRP has advanced the role of the Research Subject Advocate (RSA) by adopting the 2008 best practices defined by the CTSA Consortium. The OHSRP operations are complementary to and integrative with existing entities at the institution to promote and facilitate safe and ethical conduct of human research. The OHSRA complements the University of Pennsylvania Office of Human Research (OHR) and Institutional Review Board (IRB) in support of ensuring the safety of individuals participating in health research. The OHSRP serves as a resource to the research community and to participants; has a voice in policy regarding research ethics, participants? rights, and research safety; and plays a role in the protection of human subjects and responsible conduct of research educational programs of the institution. The OHSRP has direct access to, an authority that can temporarily suspend a research activity based on ethical and safety concerns so that problems can be explored or resolved through proper procedures. This capacity enables preliminary intervention into problems that might not necessarily invoke an institutional review board (IRB) suspension. The OHSRP has a reporting pathway to institutional officials of appropriate authority and is free of conflict of interest. human subject recruitment and protection, clinical trial technique is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156516 SCR_010046 2026-02-17 10:01:22 0
Penn Cell Center Stockroom
 
Resource Report
Resource Website
Penn Cell Center Stockroom (RRID:SCR_010003) service resource, access service resource, core facility The Cell Center Stockroom is a division of the Genetics Core Facilities (GCF). The GCF is a University service center, established in 1973 to provide consultation, training, and services in the areas of cell culture and hybridomas. Also, the GCF to provides a full range of cell culture media and molecular biology reagents needed by investigators to perform cell culture techniques in their own laboratories. The DNA Sequencing Facility, Genetic Diagnostic Laboratory and Transgenic/Chimeric Animal Facility are the remaining three divisions of the GCF. The Stockroom serves University of Pennsylvania investigators and affiliate institutions (Cancer Center, Chidren''s Hospital of Philadelphia, Hospital of the Unviersity of Pennsylvania, The Wistar Institute, Monell Chemical Senses Center, and Presbyterian Hospital) by coordinating relations with various suppliers of molecular biological research materials. This involves not only bulk purchasing of these products, but the negotiation of discounts and convenient delivery arrangements. There are over 1,400 products on-site for immediate delivery in the Stockroom. Special ordering of non-regularly stocked products is available from 24 bioreagent vendors with discounted pricing and overnight delivery. List of Stockroom Vendors: * Accutek Laboratories * Amaxa Biosystems * Ambion, Inc. * Applied Biosystems * Atlanta Biologicals * Bio-Rad Laboratories * Biowhittaker * Cell Center Services * Cell Signaling Technologies * Clontech Laboratories * Collaborative * Denville Scientific * Difco Laboratories * EMD Chemicals * Fermentas * Fisher (Thermo) Scientific * Fuji Film * GE/Amersham Bioscience * Gemini Bio-Products�� * Hyclone Laboratories * Integrated DNA Technologies * Invitrogen * ISC Bioexpress * Kodak * KPL, Inc. * Life Technologies * Lonz A* MediaTech * Millipore * New England Biolabs * Open Biosystems * Perkin Elmer Life Sciences * Promeg A* Qiagen * Rainin Instruments * Roche�� * Sigma-Aldrich * Stratagene/Agilent Technologies * TruMark Scientific * USB Corporation/Affymetrix * VWR International * Zen-Bio, Inc. is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156469 SCR_010003 2026-02-17 10:01:38 0
Penn Clinical Cell and Vaccine Production Facility
 
Resource Report
Resource Website
Penn Clinical Cell and Vaccine Production Facility (RRID:SCR_010007) service resource, access service resource, core facility Core facility that provides the following services: Cryopreservation, Clinical Cell and Vaccine Production Facility quality control and quality assurance services, Clinical Cell and Vaccine Production Facility quality control training, Conjugation of proteins or antibodies to magnetic beads and quality control, Clinical Cell and Vaccine Production Facility vaccine preparation service, Enrichment of lymphocytes or monocytes from apheresis collection, WBC, lymphocyte and monocyte count, Conversion of patient/donor plasma to serum, Depletion of cell subpopulation from apheresis or lymphocytes, Clinical Cell and Vaccine Production Facility quality control testing. The Clinical Cell and Vaccine Production Facility (CVPF) is a GMP facility accredited by the Foundation for the Accreditation of Cellular Therapy (FACT) and a Department of Pathology/Lab Medicine and NCI approved Abramson Cancer Center Shared Resource. The CVPF provides focused scientific, technical and regulatory support for investigator initiated investigational new drug applications (INDs) in cell and gene therapy. Under compliance of FDA 21 CFR Parts 210 and 211, the CVPF performs cell processing on a range of different cell types, to include bone marrow derived CD4+ and CD8+ T lymphocytes, dendritic cells, and marrow stromal cells (aka mesenchymal stem cells). In each of these cases, cells are expanded ex vivo with or without genetic modification to the cells before being reintroduced back into the patient, either alone or in combination with other therapies such as vaccines. The overall mission of the Clinical Cell and Vaccine Production Facility is to help translate insights into novel cellular therapies. cryopreservation, quality control, protein conjugation, antibody conjugation, vaccine preparation, cell separation, cell counting, material component separation is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156473 SCR_010007 2026-02-17 10:01:38 0
Penn Community Engagement and Research Core
 
Resource Report
Resource Website
Penn Community Engagement and Research Core (RRID:SCR_010008) service resource, access service resource, core facility Core facility that provides the following services: Community engagement and research consultation services. Mission: The purpose of the Community Engagement and Research Core in the Penn CTSA is to facilitate community-based research and community engagement, especially community-based participatory research, and enhance the translation of research and technological developments to key public health and community stakeholders. Goals: 1. Foster community-based participatory research projects through developing training programs and integrating lectures into existing academic programs 2. Determine community health needs and priorities 3. Promote community-based research within the area of health disparities through seminar series 4. Continue the involvement in community outreach and education events to engage the community 5. Fund the conduct of CEAR Core pilot studies 6. Facilitate the use of academic-community partnerships to aid in the recruitment of subjects community-based participatory research is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156475 SCR_010008 2026-02-17 10:01:34 0
Penn/CHOP CTRC Bionutrition Research Core Dietary Assessment
 
Resource Report
Resource Website
Penn/CHOP CTRC Bionutrition Research Core Dietary Assessment (RRID:SCR_010009) service resource, access service resource, core facility Core facility that provides the following services: Body composition measurements, Resting energy expenditure analysis. Nutrition plays a vital role in health at all ages. The Clinical and Translational Research Center offers a Bionutrition Research Unit (BRU) to facilitate and implement clinical and translational research services. Research dietitians assist investigators with research design, implementation, data collection and analysis in study protocols. The Dietary Assessment Unit of the Nutrition Core provides a broad range of nutrition-related research services to investigators at the Children''s Hospital of Philadelphia, the Hospital of the University of Pennsylvania (HUP) and Penn Presbyterian Medical Center (PMC). anthropometric analysis, indirect calorimetry is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156510 SCR_010009 2026-02-17 10:01:41 0
Penn Electron Microscopy Resource Laboratory
 
Resource Report
Resource Website
Penn Electron Microscopy Resource Laboratory (RRID:SCR_010010) service resource, access service resource, core facility Core facility that provides the following services: Biological specimen sample preparation for transmission electron microscopy, Phenotypic characterization and ultrastructural analysis of biological specimens, Consultation for transmission electron microscopy experiments, usage, and data presentation, Transmission electron microscopy image construction tomography service, Training in transmission electron microscope operation, Scanning electron microscopy service, Transmission electron microscope access. Structural organization is underlies nearly all cellular, molecular and biochemical processes in biological systems. The Electron Microscopy Resource Laboratory (EMRL) at Penn is dedicated to analysis of biological samples by electron microscopy (EM). The primary goal of the EMRL is to promote biomedical research by offering high quality EM imaging services at a low cost. With a team of experienced professional staff and state-of-the-art imaging equipment, the EMRL offers users a full spectrum of both transmission EM and scanning EM services. These services include: specimen preparation (including fixation, embedding, and sectioning of cells and tissues or preparation of non-cellular materials), operation of equipment, data acquisition, data interpretation, and free instruction on all aspects of EM analysis. We also offer free assistance on the preparation of manuscript and grant applications that incorporate various forms of EM analysis. For most users, the Core will perform a complete analysis from sample preparation through collection of data, most often with the user present during data collection. More experienced users can perform the work themselves, with the Core providing guidance and assistance as needed. The Core staff and affiliated Scientific Advisory Committee members are always available for consulting on the morphological aspects of a project, and the Core staff is willing to custom-design services to fit any investigator''s needs. cryosectioning, immunogold labeling, fixation, transmission electron microscopy, tissue embedding, tissue sectioning, staining, polymerization, cell fixation, single particle analysis, electron tomography, tissue fixation, sample preparation for assay, biospecimen preparation, data analysis, data visualization, collecting specimen from organism, image visualization and analysis, scanning electron microscopy is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156477 SCR_010010 2026-02-17 10:01:21 0
Penn Gene Targeting Service
 
Resource Report
Resource Website
Penn Gene Targeting Service (RRID:SCR_010013) service resource, access service resource, core facility The Penn Gene Targeting Service (PGT) is run by the Penn Gene Targeting Core and Laboratory in collaboration with two other Penn Cores (DNA Sequencing Facility and the Transgenic and Chimeric Mouse Facility) and has the capability to generate from scratch almost any type of genetically modified mouse. This includes complete knockout of any gene, tissue-specific and/or drug-inducible knockout of any gene, targeted mutagenesis of any region of any gene (knockin), tissue-specific activation of an endogenous gene using loxP flanked stop cassettes, and tissue-specific and/or drug-inducible transgene expression from defined loci. For details regarding services and prices please consult the PGT home page of the Department of Genetics and/or directly contact Dr. Tobias Raabe. The Client lab does not need to be involved in any experimental step and only needs to breed the resulting mice. However, if desired, participation of the client lab in almost any experimental step is possible. PGT has an outstanding record of germ line transmission and so far over 32 targeted mice - more than 12 in the desirable C57BL6 background - have been made, starting either with molecular design and construction of the targeting vector or with electroporation of an existing targeting vector into ES cells. is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
nlx_156479 SCR_010013 2026-02-17 10:01:41 0
University of Pennsylvania Molecular Profiling Facility
 
Resource Report
Resource Website
University of Pennsylvania Molecular Profiling Facility (RRID:SCR_010014) Upenn Molecular Profiling Facility, Upenn Molecular Profiling service resource, access service resource, core facility Core provides full service whole genome and targeted molecular profiling of DNA and RNA on multiple platforms. The Facility offers a range of cost and performance options suitable for a variety of experimental projects. While the Facility staff performs most of the assays, investigator-performed studies are actively encouraged through the sharing of Facility procedures, individualized training of investigators or their technical staff, and use of core equipment. DNA Profiling, RNA Profiling, genome analysis is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
Available to external user nlx_156491 http://eagle-i.itmat.upenn.edu/i/00000138-baa3-fbbc-9cd7-d7e280000000 https://pathbio.med.upenn.edu/pbr/portal/mpf/ SCR_010014 University of Pennsylvania, Upenn, Molecular Profiling, Genetics, Facility 2026-02-17 10:01:21 0
University of Pennsylvania High-performance Computing
 
Resource Report
Resource Website
University of Pennsylvania High-performance Computing (RRID:SCR_010016) UPenn HPC, Penn HPC, PMACS HPC, HPC, High-performance Computing service resource, access service resource, core facility The High-Performance Computing (HPC) Facility provides the hardware and staff to support bioinformatics and biocomputational research. The central component of this facility is a large cluster of 64 high-speed compute nodes, along with approximately 900 terabyte of shared disk storage and nearly 1.8 petabytes of archival storage. High-Performance Computing, Computing, biocomputational, bioinformatic is listed by: Eagle I
has parent organization: University of Pennsylvania; Philadelphia; USA
Available to external user nlx_156481 https://www.med.upenn.edu/hpc/ http://www.pennhpc.org/ SCR_010016 Upenn, High-performance Computing, HPC 2026-02-17 10:01:34 0

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