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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SOURCE
 
Resource Report
Resource Website
50+ mentions
SOURCE (RRID:SCR_005799) SOURCE data analysis service, database, service resource, production service resource, data or information resource, analysis service resource SOURCE compiles information from several publicly accessible databases, including UniGene, dbEST, UniProt Knowledgebase, GeneMap99, RHdb, GeneCards and LocusLink. GO terms associated with LocusLink entries appear in SOURCE. The mission of SOURCE is to provide a unique scientific resource that pools publicly available data commonly sought after for any clone, GenBank accession number, or gene. SOURCE is specifically designed to facilitate the analysis of large sets of data that biologists can now produce using genome-scale experimental approaches Platform: Online tool genomic, functional annotation, ontology, gene expression, gene, genome, statistical analysis, bio.tools, FASEB list is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: SMD
NIGMS ;
NCI CA85129-04;
NIGMS GM07365
PMID:12519986 Restricted biotools:source, nlx_149287 https://login.stanford.edu/idp/profile/SAML2/Redirect/SSO?execution=e1s1
https://bio.tools/source
SCR_005799 2026-02-15 09:19:04 69
SEECER
 
Resource Report
Resource Website
10+ mentions
SEECER (RRID:SCR_005274) SEECER software application, sequence analysis software, data processing software, algorithm resource, software resource, data analysis software Algorithm for sequencing error correction of RNA-seq data sets. SEECER removes mismatch and indel errors from the raw reads and improves downstream analysis of the data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Carnegie Mellon University; Pennsylvania; USA
PMID:23558750 Free, Available for download OMICS_01236, biotools:seecer https://bio.tools/seecer SCR_005274 SEECER - SEquencing Error CorrEction for Rna reads 2026-02-15 09:18:56 12
Bioinformatic Harvester IV (beta) at Karlsruhe Institute of Technology
 
Resource Report
Resource Website
1000+ mentions
Bioinformatic Harvester IV (beta) at Karlsruhe Institute of Technology (RRID:SCR_008017) software application, data processing software, database, software resource, data acquisition software, data or information resource Harvester is a Web-based tool that bulk-collects bioinformatic data on human proteins from various databases and prediction servers. It is a meta search engine for gene and protein information. It searches 16 major databases and prediction servers and combines the results on pregenerated HTML pages. In this way Harvester can provide comprehensive gene-protein information from different servers in a convenient and fast manner. As full text meta search engine, similar to Google trade mark, Harvester allows screening of the whole genome proteome for current protein functions and predictions in a few seconds. With Harvester it is now possible to compare and check the quality of different database entries and prediction algorithms on a single page. Sponsors: This work has been supported by the BMBF with grants 01GR0101 and 01KW0013. function, gene, bioinformatics, data, database, human, meta search engine, prediction, protein, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: Karlsruhe Institute of Technology; Karlsruhe; Germany
biotools:harvester, nif-0000-10169 https://bio.tools/harvester SCR_008017 Harvester IV 2026-02-15 09:19:41 1480
IDEAL - Intrinsically Disordered proteins with Extensive Annotations and Literature
 
Resource Report
Resource Website
10+ mentions
IDEAL - Intrinsically Disordered proteins with Extensive Annotations and Literature (RRID:SCR_006027) IDEAL data analysis service, database, service resource, production service resource, data or information resource, analysis service resource IDEAL, Intrinsically Disordered proteins with Extensive Annotations and Literature, is a collection of knowledge on experimentally verified intrinsically disordered proteins (IDPs) or intrinsically disordered regions (IDRs). IDEAL contains manually curated annotations on IDPs in locations, structures, and functional sites such as protein binding regions and posttranslational modification sites together with references and structural domain assignments. Protean segment One of the unique phenomena seen in IDPs is so-called the coupled folding and binding, where a short flexible segment can bind to its binding partner with forming a specific structure to act as a molecular recognition element. IDEAL explicitly annotates these regions as protean segment (ProS) when unstructured and structured information are both available in the region. Access to the data All the entries are tabulated in the list and individual entries can be retrieved by using the search tool at the upper-right corner in this page. IDEAL also provides the BLAST search, which can find homologs in IDEAL. All the information in IDEAL can be downloaded in the XML file. intrinsically disordered protein, protein, intrinsically disordered region, region, location, structure, functional site, protein binding region, binding region, posttranslational modification site, reference, structural domain assignment, blast, homolog, simian virus 40, epstein-barr virus, human herpesvirus 1, residue, protean segment, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Nagoya University; Nagoya; Japan
Japanese Ministry of Education Culture Sports Science and Technology MEXT PMID:22067451 biotools:ideal, nlx_151427 https://bio.tools/ideal SCR_006027 IDEAL - Intrinsically Disordered proteins with Extensive Annotations Literature, Intrinsically Disordered proteins with Extensive Annotations and Literature 2026-02-15 09:19:17 10
Pathbase
 
Resource Report
Resource Website
10+ mentions
Pathbase (RRID:SCR_006141) Pathbase ontology, database, software resource, data access protocol, web service, service resource, storage service resource, data repository, data or information resource, image collection, controlled vocabulary, image repository Database of histopathology photomicrographs and macroscopic images derived from mutant or genetically manipulated mice. The database currently holds more than 1000 images of lesions from mutant mice and their inbred backgrounds and further images are being added continuously. Images can be retrieved by searching for specific lesions or class of lesion, by genetic locus, or by a wide set of parameters shown on the Advanced Search Interface. Its two key aims are: * To provide a searchable database of histopathology images derived from experimental manipulation of the mouse genome or experiments conducted on genetically manipulated mice. * A reference / didactic resource covering all aspects of mouse pathology Lesions are described according to the Pathbase pathology ontology developed by the Pathbase European Consortium, and are available at the site or on the Gene Ontology Consortium site - OBO. As this is a community resource, they encourage everyone to upload their own images, contribute comments to images and send them their feedback. Please feel free to use any of the SOAP/WSDL web services. (under development) histopathology, photomicrograph, macroscopic, mutant, genetically manipulated, pathology, transgenic, rodent, mpath ontology, mouse pathology ontology, skinbase, genotype, skin, gene, tissue, hair, mutant mouse strain, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
has parent organization: University of Cambridge; Cambridge; United Kingdom
is parent organization of: Mouse Pathology Ontology
Lesion, Mutant mouse strain, Inbred mouse strain North American Hair Research Society ;
Ellison Medical Foundation ;
European Union QLRI-1999-00320;
European Union LSHG-CT-2006-037188;
NCI CA089713;
NCRR RR17436;
NIH AR49288
PMID:20587689
PMID:15623888
PMID:14681470
Except where otherwise noted, Creative Commons Attribution-NonCommercial-ShareAlike License, v3 Unported, Images on the database remain the property of the persons generously allowing their images to be used and are acknowledged within each record. Images should not be modified, Reproduced or disseminated without the express permission of the submitter. biotools:pathbase, nlx_151637 https://bio.tools/pathbase SCR_006141 Pathbase - European mutant mouse pathology database 2026-02-15 09:19:09 11
DARC - Database for Aligned Ribosomal Complexes
 
Resource Report
Resource Website
10+ mentions
DARC - Database for Aligned Ribosomal Complexes (RRID:SCR_006932) DARC data analysis service, database, model, service resource, production service resource, data or information resource, analysis service resource A database for aligned ribosomal complexes that provides a resource for directly comparing the structures. A collection of files deposited in the RCSB protein data bank and the Electron Microscopy Data Bank have been aligned so as to make direct comparison of the structures possible. An easy-to-use, searchable interface allows users to access and download >130 cryo-EM maps and >300 atomic models in the format of brix and pdb files, respectively. The aligned coordinate system substantially simplifies direct visualization of conformational changes in the ribosome, such as subunit rotation and head-swiveling, as well as direct comparison of bound ligands, such as antibiotics or translation factors. ribosomal complex, cryo-electron microscopy, ribosomal particle, atomic model, ribosome, x-ray crystallography, structure, bio.tools uses: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
uses: Electron Microscopy Data Bank at PDBe (MSD-EBI)
is listed by: Debian
is listed by: bio.tools
has parent organization: Ludwig-Maximilians-University; Munich; Germany
DFG SFB594;
DFG SFB646;
DFG WI3285/1-1
PMID:22009674 biotools:darc_site, nlx_149452 https://bio.tools/darc_site SCR_006932 The DARC site, Database for Aligned Ribosomal Complexes, Database for Aligned Ribosomal Complexes (DARC), DARC site 2026-02-15 09:19:24 27
PLEXdb - Plant Expression Database
 
Resource Report
Resource Website
10+ mentions
PLEXdb - Plant Expression Database (RRID:SCR_006963) PLEXdb portal, data analysis service, database, service resource, storage service resource, production service resource, data repository, data or information resource, topical portal, analysis service resource PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens. PLEXdb is a genotype to phenotype, hypothesis building information warehouse, leveraging highly parallel expression data with seamless portals to related genetic, physical, and pathway data. The integrated tools of PLEXdb allow investigators to use commonalities in plant biology for a comparative approach to functional genomics through use of large-scale expression profiling data sets. gene expression, plant, plant pathogen, genotype, phenotype, genetic, physical, pathway, plant biology, compare, functional genomics, expression profiling, expression atlas, pathogen, genome, anova, cluster, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: FuncExpression
has parent organization: Iowa State University; Iowa; USA
UniNSF DBI-0543441;
NSF IOS-0922746;
USDA 3625-21000-049-00D
PMID:22084198 biotools:plexdb, r3d100011516, nlx_149236 https://bio.tools/plexdb
https://doi.org/10.17616/R39D13
SCR_006963 PLEXdb - Gene expression resources for plants and plant pathogens, Plant Expression Database 2026-02-15 09:19:24 21
HTSeq
 
Resource Report
Resource Website
5000+ mentions
HTSeq (RRID:SCR_005514) HTSeq software application, data processing software, software resource, standalone software, authoring tool THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software Python package that provides infrastructure to process data from high-throughput sequencing assays. While the main purpose of HTSeq is to allow you to write your own analysis scripts, customized to your needs, there are also a couple of stand-alone scripts for common tasks that can be used without any Python knowledge. python, high-throughput sequencing assay, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: European Molecular Biology Laboratory
DOI:10.1093/bioinformatics/btu638 THIS RESOURCE IS NO LONGER IN SERVICE biotools:htseq, OMICS_01053 https://bio.tools/htseq http://www-huber.embl.de/users/anders/HTSeq/, https://sources.debian.org/src/python3-htseq/ SCR_005514 HTSeq: Analysing high-throughput sequencing data with Python 2026-02-15 09:18:58 8587
GeneTalk
 
Resource Report
Resource Website
10+ mentions
GeneTalk (RRID:SCR_005231) GeneTalk portal, database, service resource, storage service resource, blog, data repository, community building portal, data or information resource, narrative resource A web-based tool, knowledgebase and community for analysis and interpretation of human variant files. VCFs (Variant Call Formats) are preprocessed and annotated, you can filter them, access all databases and provide your expertise to the community by creating annotations. sequence variant, annotation, exome sequencing, genetic variant, gene, data sharing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:22826540 The community can contribute to this resource, Free, (during beta period) OMICS_00270, biotools:genetalk https://bio.tools/genetalk SCR_005231 GeneTalk - The Professional Network and Online Tool for Geneticists 2026-02-15 09:18:55 29
MUSCLE
 
Resource Report
Resource Website
10000+ mentions
MUSCLE (RRID:SCR_011812) MUSCLE software application, data analysis service, data processing software, software resource, service resource, alignment software, production service resource, image analysis software, analysis service resource, data analysis software Multiple sequence alignment method with reduced time and space complexity.Multiple sequence alignment with high accuracy and high throughput. Data analysis service for multiple sequence comparison by log- expectation. bio.tools is used by: TranslatorX
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: PREFAB
has parent organization: European Bioinformatics Institute
PMID:15034147
PMID:15318951
DOI:10.1093/nar/gkh340
biotools:muscle, OMICS_00982 https://bio.tools/muscle
http://www.drive5.com/muscle/
https://www.drive5.com/muscle/manual/
https://www.drive5
http://bioconductor.org/packages/release/bioc/html/muscle.html.com/muscle/manual/install.html
https://sources.debian.org/src/muscle/
SCR_011812 MUltiple Sequence Comparison by Log- Expectation 2026-02-15 09:20:24 16137
neXtProt
 
Resource Report
Resource Website
100+ mentions
neXtProt (RRID:SCR_008911) topical portal, data or information resource, database, portal THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2025. Human protein knowledge platform. Knowledge platform for human proteins selects and filters high throughput data pertinent to human proteins from UniProtKB. Extends UniProtKB/Swiss-Prot annotations for human proteins to include several new data types. Protein, proteomics, sirna, 3d, pathway, variant, protein-protein interaction, protein-drug interaction, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: UniProtKB
has parent organization: SIB Swiss Institute of Bioinformatics
Swiss Commission for Technology and Innovation ;
SIB
PMID:22139911 THIS RESOURCE IS NO LONGER IN SERVICE biotools:nextprot, nlx_151482 https://bio.tools/nextprot SCR_008911 2026-02-15 09:19:59 166
PLINK/SEQ
 
Resource Report
Resource Website
50+ mentions
PLINK/SEQ (RRID:SCR_013193) software application, software library, software toolkit, software resource An open-source C/C++ library for working with human genetic variation data. The specific focus is to provide a platform for analytic tool development for variation data from large-scale resequencing projects, particularly whole-exome and whole-genome studies. However, the library could in principle be applied to other types of genetic studies, including whole-genome association studies of common SNPs. (entry from Genetic Analysis Software) gene, genetic, genomic, c/c++, r, macos, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is related to: PLINK
has parent organization: Harvard University; Cambridge; United States
Open unspecified license nlx_154213, biotools:plink-seq https://bio.tools/plink-seq SCR_013193 2026-02-15 09:20:25 77
PASA
 
Resource Report
Resource Website
500+ mentions
PASA (RRID:SCR_014656) software application, sequence analysis software, data processing software, software resource, data analysis software Gene structure annotation and analysis tool that uses spliced alignments of expressed transcript sequences to automatically model gene structures. It also incorporates gene structures based on transcript alignments into existing gene structure annotations. It is one component of a larger eukayotic annotation pipeline implemented at the Broad Institute. gene structure, annotation, gene structure analysis tool, spliced alignment, transcript sequence, bio.tools is used by: BRO_annotation
is listed by: Debian
is listed by: bio.tools
DOI:10.1093/nar/gkg770 Available for download biotools:PASA https://bio.tools/PASA SCR_014656 Program to Assemble Spliced Alignments (PASA), Program to Assemble Spliced Alignments 2026-02-15 09:20:45 999
Molecular Dynamics Workflow (BioKepler)
 
Resource Report
Resource Website
1+ mentions
Molecular Dynamics Workflow (BioKepler) (RRID:SCR_014389) workflow software, software application, data processing software, software resource A workflow for running molecular dynamics simulations. It can be used for all-atom molecular dynamic simulations, which involve five steps of minimization, one step of heating, three steps of equilibration, and one or more instances of production. The input is a set of directories that include the MD simulation input scripts, system topology and coordinate files. Output files are list of plots, simulation trajectories, intermediate files, restart files, and the like. workflow, MD, molecular dynamics, simulation, software, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: bioKepler
has parent organization: University of California at San Diego; California; USA
NIGMS P41GM103426 Requires Linux biotools:ambergpumdsimulation http://nbcr.ucsd.edu/data/downloads/workflows/
https://bio.tools/ambergpumdsimulation
SCR_014389 Molecular Dynamics Workflow, AmberGPUMDSimulation, Molecular Dynamics Workflow Software, Amber GPUMD Simulation 2026-02-15 09:20:56 1
tximport
 
Resource Report
Resource Website
50+ mentions
tximport (RRID:SCR_016752) software application, data processing software, data analysis software, software resource Software R package for importing pseudoaligned reads into R for use with downstream differential expression analysis. Used for import and summarize transcript level estimates for transcript and gene level analysis. pseudoaligned, reads, R, differential, expression, analysis, gene, transcript, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
works with: edgeR
works with: DESeq2
SNSF 143883;
European Commission ;
NCI T32 CA009337
DOI:10.12688/f1000research.7563.1 Free, Available for download, Freely available biotools:tximport https://bioconductor.org/packages/tximport/
https://bioconductor.org/packages/devel/bioc/vignettes/tximport/inst/doc/tximport.html
https://github.com/F1000Research/tximport
https://bio.tools/tximport
https://zenodo.org/record/35123#.W_w3behKiM8 SCR_016752 tximport v1.4.0 2026-02-15 09:21:55 91
Nephele
 
Resource Report
Resource Website
10+ mentions
Nephele (RRID:SCR_016595) data analysis service, software resource, web application, service resource, production service resource, analysis service resource Cloud based platform for simplified, standardized and reproducible microbiome data analysis. Allows users to process microbiome datasets through pipelines of existing software tools. microbiome, datasets, process, analyze, metagenome, sequencing, data, bio.tools uses: mothur
uses: QIIME
uses: biobakery
uses: A5-miseq
is listed by: NIAID
is listed by: bio.tools
is listed by: Debian
has parent organization: OCICB
NIH Department of Health and Human Services GS35F0373X PMID:29028892 Free, Available for download, Freely available biotools:nephele https://github.com/niaid/Nephele
https://bio.tools/nephele
SCR_016595 2026-02-15 09:21:44 27
ngsRelate
 
Resource Report
Resource Website
1+ mentions
ngsRelate (RRID:SCR_016588) software application, data processing software, data analysis software, software resource Software tool for estimating pairwise relatedness from next-generation sequencing data. estimating, pairwise, relatedness, next, generation, sequencing, data, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
Danish National Research Foundation ;
Danish Council for Independent Research
PMID:26323718 Free, Available for download, Freely available biotools:ngsRelateV2, biotools:ngsrelate https://bio.tools/ngsRelateV2
https://bio.tools/ngsrelate
http://www.popgen.dk/software/index.php?title=NgsRelate&oldid=694 SCR_016588 ngsRelateV2 2026-02-15 09:21:08 6
HAPLOCLUSTERS
 
Resource Report
Resource Website
HAPLOCLUSTERS (RRID:SCR_007439) HAPLOCLUSTERS software application, software resource Software program designed to detect excess haplotypes sharing in datasets consisting of case and control haplotypes. Excess haplotype sharing can be seen around disease loci in case samples since LD persists longer here than in the controls where LD is persisting only according to the relatedness of the individuals in the population, i.e. the age of the population. (entry from Genetic Analysis Software) gene, genetic, genomic, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
Aging nlx_154014, biotools:haploclusters https://bio.tools/haploclusters SCR_007439 2026-02-15 09:19:35 0
LINKAGE
 
Resource Report
Resource Website
LINKAGE (RRID:SCR_007033) software application, software resource Standard software package for genetic linkage called LINKAGE. Genetic linkage analysis is statistical technique used to map genes and find approximate location of disease genes. Genetic linkage analysis, map genes, find location, disease, genes is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is related to: FASTLINK
nlx_154346, biotools:linkage https://bio.tools/linkage
https://gaow.github.io/genetic-analysis-software/l/lcp/
https://gaow.github.io/genetic-analysis-software/l/linkage-general-pedigrees/
http://www.jurgott.org/linkage/LinkagePC SCR_007033 , Linkage Control Program 2026-02-15 09:19:21 0
MULTIMAP
 
Resource Report
Resource Website
10+ mentions
MULTIMAP (RRID:SCR_007168) MULTIMAP software application, software resource Software program for automated construction of genetic maps (entry from Genetic Analysis Software) gene, genetic, genomic, lisp, unix, (sun/compaq-alpha/hp..), bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154013, biotools:multimap https://bio.tools/multimap http://compgen.rutgers.edu/Multimap/ SCR_007168 2026-02-15 09:19:29 27

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