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https://research.pasteur.fr/en/team/human-disease-models-core-facility/

Core Facility produces mice harboring human immune system and provides expertise for possible applications of this model. HIS mice engrafted with human Hematopoietic stem cells are advantageous in vivo models for long term studies in field of human immune cells biology, immune oncology and infectious disease. They constitute small animal model in which to analyze potency and safety of small animal model modulating immune system.

Proper citation: Pasteur Institute Human Disease Models Core Facility (RRID:SCR_023881) Copy   

•   Source: SciCrunch Registry

https://crhmr.ciusss-estmtl.gouv.qc.ca/en/research/technical-platforms/flow-cytometry

Offers sorting and flow cytometry services. Equipment includes Cytek Aurora, BD ARIA III, SONY cell sorters and Cytek Aurora, 2 BD LSRFortessa X-20, BD FACSCelesta,BD LSR II, CANTO A analyzers. Individual mandatory training is necessary to access this facility. ARIA III cell sorter as well as SONY SH800 are equipped with negative pressure hood allowing sorting of potentially infectious samples including human cells from healthy donors.

Proper citation: University of Montreal CR-HMR Flow Cytometry Core Facility (RRID:SCR_023638) Copy   

•   Source: SciCrunch Registry

https://imaging.au.dk

Core Facility offers equipment for wide range of light microscopy applications as well as access to advanced bioimaging software. Specialized staff offers personal training and assistance.

Proper citation: Aarhus University Bioimaging Core Facility (RRID:SCR_023876) Copy   

•   Source: SciCrunch Registry

https://www.beatson.gla.ac.uk/advanced-technologies/bair.html

Core to uncover and interrogate important molecular pathways in cancer. Offers training scientists in all stages of modern microscopical research from advice on experimental design and sample preparation, basic and advanced microscope operation and data acquisition through to quantitative image analysis and interpretation.

Proper citation: Beatson Institute for Cancer Research United Kingdom Beatson Advanced Imaging Resource Core Facility (RRID:SCR_023875) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/ids/

Provides research pharmacy services to Emory patients, investigators and sponsors, and ensures that research drugs are handled safely, accurately and effectively. IDS strives to provide quality and efficiency in research drug management, enhance patient care in research and ensure audit readiness at all times.

Proper citation: Emory University Emory Investigational Drug Service Core Facility (RRID:SCR_023532) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/hplc/

Core offers services to identify and quantify monoamine neurotransmitters, amino acids, purine bases, and nucleotides from variety of biological samples. Provides expertise to develop and validate HPLC methods to measure other small molecule compounds, peptides, and proteins.

Proper citation: Emory University Emory HPLC Bioanalytical Core Facility (RRID:SCR_023531) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/eipc/

Core is full service proteomics facility offering Emory researchers ability to use the latest technologies in their research.

Proper citation: Emory University Emory Integrated Proteomics Core Facility (RRID:SCR_023530) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/biorepository-resource-center

Serves to accession, process, store, and manage distribution of research biospecimens for biobanking efforts. Core offers specimen processing, and RNA and DNA extraction services.

Proper citation: Children's Hospital of Philadelphia Research Institute CHOP Biorepository Resource Center Core Facility (RRID:SCR_023768) Copy   

•   Source: SciCrunch Registry

https://biologics.utexas.edu/research/advanced-protein-therapeutics-core

Core catalyzes translation of scientific discoveries into novel protein cancer therapies. Offers therapeutic antibody and enzyme discovery, engineering, and optimization services.

Proper citation: University of Texas at Austin Advanced Protein Therapeutics Core Facility (RRID:SCR_023740) Copy   

•   Source: SciCrunch Registry

https://health.ucdavis.edu/cancer/research/sharedresources/biostatistics.html

Provides expertise in design, analysis and reporting of cancer related studies, including basic, translational, clinical and population based research. BSR affiliated faculty and staff work with investigators from the earliest stages of study planning. The shared resource is especially committed to mentoring early career cancer researchers.

Proper citation: University of California Davis Health Biostatistics Shared Resource Core Facility (RRID:SCR_023585) Copy   

•   Source: SciCrunch Registry

https://health.ucdavis.edu/cancer/research/sharedresources/combichem.html

Provides high throughput screening platform to discover unique chemical probes against biological targets using various one bead one compound and one bead two compound combinatorial libraries.Interacts closely with resource users on optimization of the lead compounds via focused libraries and standard medicinal chemistry techniques. Provides custom synthesis of telodendrimer based micellar nanoparticle platform for efficient drug delivery.

Proper citation: University of California Davis Health Combinatorial Chemistry and Chemical Biology Shared Resource Core Facility (RRID:SCR_023584) Copy   

•   Source: SciCrunch Registry

https://www.dartmouth-hitchcock.org/pathology/research#ibr

Institutional resource collaboratively run by Office of Research Operations and Department of Pathology and Laboratory Medicine that provides services in support of Dartmouth Research Communities and in alignment with Institutional Review Board approved protocols including Clinical Trials. Provides collection, processing, storage, and distribution of annotated human bio-specimens to clinicians and other investigators in support of clinical trials, industry sponsored projects, and scientific investigations.

Proper citation: Dartmouth Health Hitchcock Medical Center Biorepository Core Facility (RRID:SCR_023735) Copy   

•   Source: SciCrunch Registry

https://bic.nd.edu/

Offers instrumentation dedicated to characterizing biomolecular conformations and interactions, as well as equipment for isolation and purification of macromolecules for subsequent detailed biophysical analysis.

Proper citation: University of Notre Dame ND Biophysics Instrumentation Core Facility (RRID:SCR_023867) Copy   

•   Source: SciCrunch Registry

https://health.ucdavis.edu/cancer/research/sharedresources/cmp.html

Provides services to support the development and implementation of clinical trials at UC Davis Comprehensive Cancer Center. Oversees high quality collection, processing, and analysis of clinical specimens,typically but not exclusively blood specimens, for pharmacokinetic and pharmacodynamics studies. Conducts preclinical modeling of novel anti cancer agents to test hypotheses and develop scientific rationale required for translation of laboratory concepts into clinical trials, including assessment of DM/PK/PD properties.

Proper citation: University of California Davis Health Molecular Pharmacology Shared Resource Core Facility (RRID:SCR_023588) Copy   

•   Source: SciCrunch Registry

https://www.research.colostate.edu/epf/

Core provides pathologic services ranging from animal model troubleshooting, and tissue fixation to stain slide prep and immunohistochemistry. Offers expertise in slide interpretations and quantitative histopathology in anatomic and clinical pathology. Offers molecular pathology services via Nanostring nCounter equipment.

Proper citation: Colorado State University Experimental Pathology Core Facility (RRID:SCR_023562) Copy   

•   Source: SciCrunch Registry

https://www.feinberg.northwestern.edu/sites/transplant/research/research-cores/immune-core.html

Core of Comprehensive Transplant Center provides translational mechanistic studies in human solid organ and cellular transplantations. Provides assistance with human immune monitoring needs for translational and clinical transplantation research projects.Offers immune monitoring services for translational mechanistic studies.

Proper citation: Northwestern University Immune Monitoring Core Facility (RRID:SCR_023561) Copy   

•   Source: SciCrunch Registry

https://ibt.tamu.edu/centers/translational-cancer-research/stephan-lab/mlots/index.html

Supports lead optimization programs and has established roster of medium throughput microphysiologic screening platforms including tissue- and tumor-on-a-chip platforms, organoid, and spheroid culture systems that will be used to evaluate efficacy and toxicity of new lead compounds and drug combinations.Provides resources to identify toxic liabilities in lead series molecules before entering pre-clinical or clinical testing. MLOTS can evaluate NME for cardiovascular, neuro, or liver toxicity relative to reference standards using in vitro screening platforms. Facility will potentially enhance the effectiveness of CPRITs drug discovery programs.

Proper citation: Texas A and M University Health Institute of Biosciences and Technology Microphysiological Lead Optimization and Toxicity Screening Core Facility (RRID:SCR_023717) Copy   

•   Source: SciCrunch Registry

https://med.stanford.edu/cancer/research/shared-resources/biostatistics_research_informatics.html

Core provides statistical support to SCI members by engages them on their data related needs. Specifically, BSR members assist researchers at each stage of study’s lifecycle, including project design, mid study evaluation and interpretation and reporting of results. In addition, BSR members mentor SCI investigators in research methods. BSR assists with development and review of proposed studies and planning of research related data management systems.

Proper citation: Stanford University School of Medicine Cancer Institute Biostatistics Shared Resource Core Facility (RRID:SCR_023696) Copy   

•   Source: SciCrunch Registry

https://med.stanford.edu/spectrum/ctsa-cores-and-programs/research-methods-core/berd.html

Core provides CTR investigators with support for study design development, data curation and management, and analytic strategies. Provides infrastructure through Data Studio; Clinical Office Hours; Data Science Navigation.

Proper citation: Stanford Spectrum Biostatistics Epidemiology and Research Design Core Facility (RRID:SCR_023695) Copy   

•   Source: SciCrunch Registry

http://researchservices.pitt.edu/facilities/machine-shop

Core specializes in mechanical design, fabrication, and repair of research equipment and instrumentation.

Proper citation: University of Pittsburgh Dietrich School Machine Shop Core Facility (RRID:SCR_023720) Copy   

•   Source: SciCrunch Registry