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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://syntheticbiology.northwestern.edu/research/biofoundry/
Core facility for synthetic biology experimentation including pilot-scale fermentation, high throughput automation, biological sample analysis, and cell-free protein synthesis.
Proper citation: Northwestern University SynBio Foundry Core Facility (RRID:SCR_026869) Copy
Core provides access to analytical flow cytometry instrumentation and cell sorting services, as well as training and experimental consultation.
Proper citation: Michigan State University Flow Cytometry Core Facility (RRID:SCR_026903) Copy
https://medresearch.umich.edu/office-research/about-office-research/our-units/central-biorepository
Core provides annotated biospecimens for basic, clinical, and translational research. Helps researchers access, collect, manage, and protect biospecimens using automated processes and quality control. Offers safe and monitored management of biospecimens including temperature-controlled storage, preparation of derivatives from these specimens, aliquoting, distribution, and production of specimen collection kits.
Proper citation: University of Michigan Medical School Central Biorepository Core Facility (RRID:SCR_026845) Copy
https://www.benaroyaresearch.org/our-research/biorepositories
BRI is home to rigorously maintained biorepositories containing blood and tissue samples donated by people with immune-mediated diseases and healthy controls.Provides the collection of samples from research participants, sample processing, storage, and sharing.
Proper citation: Benaroya Research Institute BRI Biorepository Core Facility (RRID:SCR_026967) Copy
https://www.lerner.ccf.org/cores/biorobotics/
Core provides biomechanical testing of biological structures and biomaterials. Allows investigators to conduct research of mechanical properties of existing biological structures and constructs, as well as to quantify potential for new technologies and clinical advancements. Robotic simulators are built around the simVITRO software platform and are designed for in vitro simulation of major joints including knee, spine, foot, ankle, hip, shoulder, elbow, wrist and more. Provides testing capabilities for range of biomechanical modalities and will offer expert advice and support for development of new test protocols, innovative techniques for instrumentation and data collection. Modalities include tissues, joints, and multi-articular units, such as foot or spine segments.
Proper citation: Cleveland Clinic Lerner Research Institute BioRobotics and Mechanical Testing Core Facility (RRID:SCR_026849) Copy
https://www.unmc.edu/eppley/cmtdd/cores/scst.html
Core offers spatial omics processing on many different tissue types. Facility provides instrumnets including Bruker's GeoMx DSP ready for launch with anticipated launch of 10x Visium. Offers expert collaboration from project design to data handoff. Core has established workflows with additional shared resources on UNMC campus to allow for expertise throughout entire project.
Proper citation: University of Nebraska Medical Center Single Cell and Spatial Transcriptomics Core Facility (RRID:SCR_026860) Copy
https://www.ifom.eu/en/cancer-research/technological-units/electron-microscopy.php
Core performs routine transmission and scanning Electron Microscopy and all kinds of immune Electron Microscopy, correlative light electron microscopy, three-dimensional EM (3DEM), quantitative stereological evaluation of data and more.
Proper citation: Cancer Research Institute IFOM EMCT Electron Microscopy Cells & Tissues Core Facility (RRID:SCR_026863) Copy
https://www.ifom.eu/en/cancer-research/technological-units/mechanomedicine.php
Core focuses on development of innovative biomedical technologies and devices for cancer research as well as biomedical applications using microfabrication and 3D printing.
Proper citation: Cancer Research Institute IFOM CERD Cancer Engineering R&D Core Facility (RRID:SCR_026862) Copy
https://www.ifom.eu/en/cancer-research/technological-units/preclinical-models.php
Specialized laboratory designed for growth, maintenance, and experimentation of living cells under controlled conditions. This facility is used in various fields such as biomedical research, drug development, and supports the culture of primary cells, immortalized cell lines, human-induced pluripotent stem cells (hiPSCs), and organoids, among others.
Proper citation: Cancer Research Institute IFOM CPM Cellular And Preclinical Models Core Facility (RRID:SCR_026864) Copy
https://www.uoflsequencing.com/services-2-1
Provides genomic sequencing services including next-generation sequencing (NGS), single-cell analysis, and spatial transcriptomics. Offers advanced short-read and long-read sequencing technologie including our status as a PacBio Certified Service Provider.
Proper citation: University of Louisville Sequencing Technology Center Genomics Services Core Facility (RRID:SCR_027013) Copy
Core is veterinary diagnostic laboratory and research pathology core. Provides laboratory animal diagnostics, clinical and health surveillance screening necessary for the care and use of animals in research, and expert pathology support for basic and translational research.
Proper citation: University of California Davis Comparative Pathology Laboratory Core Facility (RRID:SCR_027014) Copy
https://imb.uq.edu.au/microscopy
Microscopy Facility supports cancer research, cell and developmental biology, and cross-disciplinary studies spanning molecular mechanisms to translational applications. Houses imaging platforms including widefield, confocal, multi-photon, super-resolution, spinning disk, and light sheet systems. Enables advanced modalities such as TIRF, FRET, STED, SHG/THG, and FLIM for detailed exploration of cell behaviour and microenvironments. Facility staff offer training, expert consultation, image analysis support, and troubleshooting.
Proper citation: University of Queensland Institute for Molecular Bioscience Advanced Microscopy Core Facility (RRID:SCR_026841) Copy
https://bibraincancer.umich.edu/core/high-plex-immunocytochemistry-core/
Core utilizes Akoya PhenoCycler-Fusion to enable high-plex spatial phenotyping of whole tissue slides at single-cell resolution.
Proper citation: University of Michigan Bioinnovation in Brain Cancer High-Plex Immunocytochemistry Core Facility (RRID:SCR_026843) Copy
Provides expertise through experimental design consultations,cell isolation,single cell analytics (RNA, DNA, protein),biomarker validation,novel statistical and bioinformatics analyses. Services include Single cell targeted gene expression, Single cell RNA Seq, Single cell DNA Seq, Tissue sectioning, Tissue spatial analysis, Spatial transcriptomics and proteomics.
Proper citation: University of Michigan Rogel Cancer Center Single Cell Spatial Analysis Shared Resource Core Facility (RRID:SCR_026842) Copy
Core supports basic and clinical research by providing histological and molecular expertise, technical support and consultation to research investigators. Provides histological, molecular and consultation services. Services are performed by American Society of Clinical Pathology certified histologists with expertise in routine histology, whole slide scanning, image and digital analysis, pathology services, immunohistochemistry, tissue microarray, bone histomorphometry, Visium preparations and RNAscope single and co-detection assays.
Proper citation: University of Texas MD Anderson Research Histology Core Facility (RRID:SCR_026932) Copy
https://www.cogentech.it/genomic_unit.php
Cogentech's Genomic Core Facility (GU) provides professional support for workflow of research projects, from counseling on experimental design to functional interpretation of results. Support includes identification of the most suitable methodology to achieve the experimental aim, quality control of nucleic acid, generation of indexed fragment library, sequencing according to experimental needs and bioinformatic support for selected applications. Customized protocols can be set-up as well. Sequencing data are delivered using a password protected user-friendly web interface. The laboratory is ISO9001 certified.
Proper citation: IFOM ETS Cogentech GU Genomics Core Facility (RRID:SCR_026935) Copy
https://www.cogentech.it/histology.php
Cogentech's Histopathology (HP) Core Facility provides services including consultation, tissue trimming and embedding, cutting, staining, photographic documentation for the evaluation and characterization of normal and pathological tissues. Provides Optimization of protocols for new stains or biological specimen.The laboratory is ISO9001 certified.
Proper citation: IFOM ETS Cogentech HP Histopathology Core Facility (RRID:SCR_026934) Copy
https://www.cogentech.it/integrated-genomics.php
Cogentech's Integrated Genomics Core Facility (IGU) consists of units: Molecular Biology and Sequencing, Histopathology and Bioinformatics. Molecular Biology group provides expertise in various fields of application: nucleic acid extraction from different matrices, ddPCR and various types of sequencing (customised gene panels, Lowpass WGS, WES, WGS, total RNA-Seq, mRNA Seq, TCR-Seq, 16S Metagenomic Seq, ATAC-Seq, genome-wide methylation profiling). Bioinformatics unit provides pipelines for analysis of data produced by all sequencing workflows. In addition, it provides its expertise for implementation and development of customised pipelines. Histopathology unit offers services for slide preparation and staining, image digitisation and laser-capture microdissection. The laboratory is ISO9001 certified.
Proper citation: IFOM ETS Cogentech IGU Integrative Genomics Core Facility (RRID:SCR_026938) Copy
Advanced high-field NMR facility combines many capabilities spanning solution and solid state NMR, high sensitivity cryoprobes, ultrafast spinning MAS probes, as well as Dynamic Nuclear Polarization.
Proper citation: Ohio State University Campus Chemical Instrument Center NMR Core Facility (RRID:SCR_027162) Copy
https://research.vcu.edu/cores/structural-biology/cryo-em/
Facility offers sample preparation, visualization and analysis for high resolution 3D reconstruction of frozen-hydrated proteins and macromolecular complexes. Facility is endowed with Thermofisher Scientific Tundra cryo-electron microscope, Vitrobot Mark IV cryo-plunger, Pelco easyGlow glow discharge unit, Denton DV 502B evaporator, and linux server dedicated to image processing.
Proper citation: Virginia Commonwealth University Cryo-Electron Microscopy Core Facility (RRID:SCR_027178) Copy
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