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https://resnick.caltech.edu/research/resource-centers/water-and-environment-lab-wel
Provides access to chromatography and mass spectrometry techniques including GC and GC-MS, IC and IC-MS, ICP-MS, LC and LC-MS, and other environmentally relevent techniques such as isotope ratio measurements of water, TIC/TOC, and laser diffraction particle size analysis.
Proper citation: California Institute of Technology Water and Environment Laboratory Core Facility (RRID:SCR_022714) Copy
https://www.cardiff.ac.uk/biosciences/research/technology-research-hubs/bioimaging-unit
Provides advanced light microscopy imaging modalities and histological services. Offers training and application support in experimental design, sample preparation, data generation and analysis through to scientific publication and grant assistance.
Proper citation: Cardiff University Bioimaging Hub Core Facility (RRID:SCR_022556) Copy
https://uncch.ilab.agilent.com/sc/5341/mammalian-genotyping-core/?tab=about
Core is component of Integrated Genomics Core/High Throughput Sequencing Facility. Supports population, basic, clinical and translational research by providing centralized cost efficient, high quality genotyping and methylation services using Illumina BeadArray and Infinium microarray assay technologies for Single Nucleotide Polymorphism Genotyping, Copy Number Variant, Loss of Heterozygosity, Insertions Deletion (indel), Structural Variant, and DNA Methylation Analysis. Can assist with selecting appropriate arrays to meet your needs.
Proper citation: University of North Carolina at Chapel Hill Mammalian Genotyping Core Facility (RRID:SCR_022716) Copy
https://www.ohsu.edu/integrated-genomics-laboratory
Lab houses three cores providing support and services from nucleic acid isolation through data generation on multiple genomic and molecular analysis platforms. Nucleic acid extraction, qPCR, and Nanostring profiling services are available through the Gene Profiling Shared Resource for gene expression profiling, microRNA profiling, DNA genotyping and copy number analysis, and DNA methylation analyses. Currently running QuantStudio real-time PCR system. Comprehensive RNA and DNA extraction and quality assessment services available. Massively parallel sequencing (NGS) services, including library preparation, are available through Massively Parallel Sequencing Shared Resource on Illumina NovaSeq 6000 and NextSeq platforms. 10x Genomics single-cell and single-nuclei analysis services available. Cell line authentication, DNA plating, and custom oligo services are available through DNA Services Core.
Proper citation: Oregon Health and Science University Integrated Genomics Laboratory Core Facility (RRID:SCR_022651) Copy
https://www.cincinnatichildrens.org/research/cores/mmac
Provides solutions in areas of study design, bioinformatic processing of amplicon and shotgun metagenomic sequencing data, integration of metagenomic and clinical data structures, and statistical analyses of microbial community samples. MMAC works closely with Microbial Genomics and Metagenomics Laboratory to streamline workflows for metagenomic sequencing, bioinformatic processing, and statistical analysis of microbiome projects.
Proper citation: Cincinnati Children's Hospital Microbial Metagenomics Analysis Center Microbial Genomics and Metagenomics Core Facility (RRID:SCR_022649) Copy
https://research.med.psu.edu/core-facilities/light-microscopy/
Provides consultation and training in ultra high resolution imaging of cells and tissues in fixed or live states. Provides expertise in quantitative image analysis and consultations on microscopy related research projects.
Proper citation: Penn State Hershey College of Medicine Light Microscopy Imaging Core Facility (RRID:SCR_022526) Copy
https://www.vet.upenn.edu/research/core-resources-facilities/imaging-core
Core provides access to light microscope systems to perform widefield, confocal, 2-photon/multiphoton, second harmonic generation, total internal reflection (TIRF), and high content imaging.
Proper citation: University of Pennsylvania Penn Vet Imaging Core Facility (RRID:SCR_022764) Copy
Facilitates scientific research of nervous system function to enhance development and testing of novel therapeutic strategies for treatment of nervous system disorders. Provides resource capacity typically unavailable or impractical in individual laboratory. Major areas of specialization include surgical approaches to model production and assessment, behavior testing of sensorimotor functions, in vivo electrophysiological recording (EEG, EMG, ERP). Procedures are intended for mice and rats. Procedures can be developed based on client interests.
Proper citation: University of Texas Southwestern Medical Center Neuro Models Core Facility (RRID:SCR_022529) Copy
https://bauercore.fas.harvard.edu/
Helps to advance research efforts in life sciences that cannot readily be accomplished in the traditional academic laboratory because of need for expensive instrumentation or automation, scientific or organizational infrastructure, or multidisciplinary expertise. Provides expertise and hands-on training and use of instrumentation for nominal fee. Researchers can sign up to use instrumentation through on-line scheduling system and conduct their experiments independently.
Proper citation: Harvard University Bauer Core Facility (RRID:SCR_022656) Copy
https://www.cincinnatichildrens.org/research/cores/dna-sequencing-genotyping
Supports production and analysis of DNA and RNA related data. Provides DNA and RNA sequencing, Next Generation sequencing, DNA extraction and high and low throughput SNP genotyping.
Proper citation: Cincinnati Children's Hospital DNA Sequencing and Genotyping Core Facility (RRID:SCR_022630) Copy
Supports development, scale -up and processing of innovative cell based therapies for clinical studies.
Proper citation: Cincinnati Children's Hospital Cell Manipulation Laboratory Core Facility (RRID:SCR_022627) Copy
https://www.cincinnatichildrens.org/research/cores/dmac
Centralized resource for clinical research data management, programming for clinical research databases, and statistical analysis.
Proper citation: Cincinnati Children's Hospital Data Management and Analysis Center Core Facility (RRID:SCR_022625) Copy
https://www.cincinnatichildrens.org/research/cores/mouse-core
Offers services for researchers exploring cancer systems through animal models. Provides animals from specific inbred mouse strains primarily used in cancer and hematopoietic research, offers cell transplant, harvest and irradiation services and can handle animal cancer model systems involving xenotransplant procedures.
Proper citation: Cincinnati Children's Hospital Comprehensive Mouse and Cancer Core Facility (RRID:SCR_022624) Copy
Supplies mononuclear cells, stem cells or other enriched cell populations. Provides stem cells and other tissue samples from normal donor or patient populations such as disease specific repositories or specific research studies requiring sample processing. Samples are provided fresh or cryopreserved according to availability, unprocessed or with further lab processing.Common processing techniques include PBMC isolation,Serum and plasma isolation,Separation of marker specific populations,Flow cytometric characterization of samples,Interferon gamma EliSpot.Additional services may be available upon request
Proper citation: Cincinnati Children's Hospital Cell Processing Core Facility (RRID:SCR_022623) Copy
Provides microscopes and imaging stations. Expert staff offers guide to non-expert users. Facility offers imaging expertise in Electron Microscopy, Optical Microscopy, In Vivo Imaging, and Histology.
Proper citation: University of Notre Dame Integrated Imaging Core Facility (RRID:SCR_022743) Copy
https://www.cincinnatichildrens.org/research/cores/animal
Offers behavioral phenotyping of rodent models as well as characterizing nervous system function in mouse and rat models through behavioral assays.
Proper citation: Cincinnati Children's Hospital Animal Behavior Core Facility (RRID:SCR_022621) Copy
http://www.ohsu.edu/xd/research/research-cores/small-animal-research-imaging-core/
Provides in vivo imaging technology to evaluate anatomy, tissue function, cellular and molecular phenotype, blood/fluid flow, metabolism and to assess pharmacokinetics and stem cell function in small animal models.Offers spatial resolution, temporal resolution, tissue differentiation, sensitivity for contrast agent, and performance of contrast agents. Services include MicroPET/SPECT/CT imaging,Ultra-high frequency small animal ultrasound imaging,Biophotonics imaging.
Proper citation: Oregon Health and Science University Small Animal Research Imaging Core Facility (RRID:SCR_022742) Copy
Provides Cincinnati Children s Hospital Medical Center; Cincinnati; Ohio resources in confocal, wide-field, and spatial technique applications.
Proper citation: Cincinnati Children's Hospital Confocal Imaging Core Facility (RRID:SCR_022628) Copy
https://www.cincinnatichildrens.org/research/cores/pathology-core
Provides technical support for routine morphology based techniques. Pathologists are on hand to help guide projects, interpret results and collaborate on publications. Core personnel provide technical support for routine morphology based techniques including tissue processing and embedding, routine and special histochemical staining, immunohistochemistry, in situ hybridization, and electron microscopy.
Proper citation: Cincinnati Children's Hospital Pathology Research Core Facility (RRID:SCR_022637) Copy
https://www.cincinnatichildrens.org/research/cores/metabolomics
Provides all NMR related metabolomics services on human and animal cells, biopsies and body fluids.
Proper citation: Cincinnati Children's Hospital NMR based Metabolomics Core Facility (RRID:SCR_022636) Copy
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