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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
BLASTP
 
Resource Report
Resource Website
100+ mentions
BLASTP (RRID:SCR_001010) service resource, analysis service resource, data analysis service, production service resource Data analysis service whose programs search protein databases using a protein query. The algorithms used include blastp, psi-blast, phi-blast, and delta-blast. blast, basic local alignment search tool, protein alignment, protein blast, data analysis service, protein is used by: Open Reading Frame Finder
is listed by: OMICtools
is listed by: SoftCite
has parent organization: NCBI
Freely available, Acknowledgement requested OMICS_00991 SCR_001010 blastp suite, Standard Protein BLAST 2026-02-15 09:18:01 286
WegoLoc
 
Resource Report
Resource Website
1+ mentions
WegoLoc (RRID:SCR_001402) WegoLoc service resource, analysis service resource, data analysis service, production service resource Data analysis service that predicts protein subcellular localizations of animal, fungal, plant, and human proteins based on sequence similarity and gene ontology information. subcellular localization, protein is listed by: OMICtools
is related to: Gene Ontology
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01636 SCR_001402 weighted gene ontology term based subcellular locallization prediction 2026-02-15 09:18:06 4
WoLF PSORT
 
Resource Report
Resource Website
100+ mentions
WoLF PSORT (RRID:SCR_002472) WoLF PSORT service resource, analysis service resource, data analysis service, production service resource Data analysis service for protein subcellular localization prediction. subcellular localization, protein is listed by: OMICtools Restricted OMICS_01637 SCR_002472 WoLF PSORT - Protein Subcellular Localization prediction 2026-02-15 09:18:18 129
Biomine
 
Resource Report
Resource Website
1+ mentions
Biomine (RRID:SCR_003552) Biomine data or information resource, database, service resource Service that integrates cross-references from several biological databases into a graph model with multiple types of edges, such as protein interactions, gene-disease associations and gene ontology annotations. Edges are weighted based on their type, reliability, and informativeness. In particular, it formulates protein interaction prediction and disease gene prioritization tasks as instances of link prediction. The predictions are based on a proximity measure computed on the integrated graph. gene, protein, genetics, visualization, connection, biological entity, protein interaction, disease gene, link prediction is related to: Entrez Gene
is related to: Gene Ontology
is related to: HomoloGene
is related to: InterPro
is related to: OMIM
is related to: STRING
is related to: UniProtKB
is related to: UniProt
is related to: GoMapMan
has parent organization: University of Helsinki; Helsinki; Finland
PMID:22672646 nlx_157687 SCR_003552 2026-02-15 09:18:35 4
Proteome Analyst Specialized Subcellular Localization Server
 
Resource Report
Resource Website
1+ mentions
Proteome Analyst Specialized Subcellular Localization Server (RRID:SCR_003143) PA-SUB service resource, analysis service resource, data analysis service, production service resource Web server specialized to predict the subcellular localization of proteins using established machine learning techniques. subcellular localization, protein, machine learning, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Alberta; Alberta; Canada
PMID:14990451 Free, Available for download, Freely available biotools:pa-sub, OMICS_01631 https://psort.org/#:~:text=Proteome%20Analyst's%20Subcellular%20Localization%20Server
proteins%20to%20many%20localization%20sites.
SCR_003143 2026-02-15 09:18:29 1
Retina Project
 
Resource Report
Resource Website
1+ mentions
Retina Project (RRID:SCR_002884) Retina Project atlas, data or information resource, spatially referenced dataset Collection of images from cell type-specific protein expression in retina using BAC transgenic mice. Images from cell type-specific protein expression in retina using BAC transgenic mice from GENSAT project. electrophysiology, protein expression, fluorescent, gene, amacrine cell, astrocyte, bipolar cell, blood vessel, brain, cell, ganglion cell layer, central nervous system, circuit, horizontal cell, hybridization, microglia, adult mouse, muller cell, neocortex, neuronal, photoreceptor, protein, recombinase, retina, spinal cord, mutant mouse strain, bac, retinal cell, cell type, night vision, direction, neuronal circuitry, connectivity, image collection is used by: NIF Data Federation
has parent organization: GENSAT at NCBI - Gene Expression Nervous System Atlas
Department Of Health And Human Services ;
NINDS N01 NS02331
PMID:19648912 Free, Freely available nif-0000-25587 SCR_002884 GENSAT Retina Project, Retina Project from GENSAT, The Retina Project, The Retina Project from GENSAT, GENSAT - Retina Project 2026-02-15 09:18:25 2
AmphoraNet
 
Resource Report
Resource Website
10+ mentions
AmphoraNet (RRID:SCR_005009) AmphoraNet service resource, analysis service resource, data analysis service, production service resource Webserver implementation of the AMPHORA2 workflow for phylogenetic analysis of metagenomic shotgun sequencing data. It is capable of assigning a probability-weighted taxonomic group for each phylogenetic marker gene found in the input metagenomic sample. dna sequence, amino acid sequence, dna, sequence, amino acid, phylogenetic, reliability score, nucleotide, protein, nucleotide sequence, protein sequence, phylogenetic analysis, metagenomic, metagenomics, phylotyping, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Eotvos Lorand University; Budapest; Hungary
PMID:24144838 Acknowledgement requested, Free, Public biotools:amphoranet, OMICS_01450 https://bio.tools/amphoranet SCR_005009 2026-02-15 09:18:53 16
MutationAssessor
 
Resource Report
Resource Website
500+ mentions
MutationAssessor (RRID:SCR_005762) mutationassessor.org service resource, analysis service resource, data analysis service, production service resource A web server that predicts the functional impact of amino-acid substitutions in proteins, such as mutations discovered in cancer or nonsynonymous polymorphisms. The functional impact is assessed based on evolutionary conservation of the affected amino acid in protein homologs. The method has been validated on a large set (51k) of disease associated (OMIM) and polymorphic variants., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. cancer, protein, mutation, function, amino-acid, substitution is listed by: OMICtools
is listed by: SoftCite
PMID:21727090 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00134, nlx_149228 SCR_005762 MutationAssessor - functional impact of protein mutations, MutationAssessor - functional impact of mutations, mutationassessor.org - functional impact of protein mutations 2026-02-15 09:19:03 669
Computational Biology at ORNL
 
Resource Report
Resource Website
Computational Biology at ORNL (RRID:SCR_005710) Computational Biology at ORNL service resource, analysis service resource, data analysis service, production service resource We are the Computational Biology and Bioinformatics Group of the Biosciences Division of Oak Ridge National Laboratory. We conduct genetics research and system development in genomic sequencing, computational genome analysis, and computational protein structure analysis. We provide bioinformatics and analytic services and resources to collaborators, predict prospective gene and protein models for analysis, provide user services for the general community, including computer-annotated genomes in Genome Channel. Our collaborators include the Joint Genome Institute, ORNL''s Computer Science and Mathematics Division, the Tennessee Mouse Genome Consortium, the Joint Institute for Biological Sciences, and ORNL''s Genome Science and Technology Graduate Program. genetics, research, system development, genomic sequencing, computation, genome analysis, protein structure, analysis, gene, protein, gene annotation, annotation, genome has parent organization: Oak Ridge National Laboratory nlx_149161 SCR_005710 Computational Biology at Oak Ridge National Laboratory, Computational Biology and Bioinformatics Group at ORNL, Computational Biology Bioinformatics Group at ORNL 2026-02-15 09:19:01 0
GOtcha
 
Resource Report
Resource Website
1+ mentions
GOtcha (RRID:SCR_005790) GOtcha service resource, analysis service resource, data analysis service, production service resource GOtcha provides a prediction of a set of GO terms that can be associated with a given query sequence. Each term is scored independently and the scores calibrated against reference searches to give an accurate percentage likelihood of correctness. These results can be displayed graphically. Why is GOtcha different to what is already out there and why should you be using it? * GOtcha uses a method where it combines information from many search hits, up to and including E-values that are normally discarded. This gives much better sensitivity than other methods. * GOtcha provides a score for each individual term, not just the leaf term or branch. This allows the discrimination between confident assignments that one would find at a more general level and the more specific terms that one would have lower confidence in. * The scores GOtcha provides are calibrated to give a real estimate of correctness. This is expressed as a percentage, giving a result that non-experts are comfortable in interpreting. * GOtcha provides graphical output that gives an overview of the confidence in, or potential alternatives for, particular GO term assignments. The tool is currently web-based; contact David Martin for details of the standalone version. Platform: Online tool function, protein, prediction, genome, annotation, gene, statistical analysis is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of Dundee; Scotland; United Kingdom
Wellcome Trust 060269;
European Union fifth framework QLRI-CT-2000-00127
PMID:15550167 Free for academic use nlx_149269 http://www.compbio.dundee.ac.uk/Software/GOtcha/gotcha.html SCR_005790 2026-02-15 09:19:03 1
GoAnnotator
 
Resource Report
Resource Website
1+ mentions
GoAnnotator (RRID:SCR_005792) GOAnnotator service resource, analysis service resource, data analysis service, production service resource A tool for assisting the GO annotation of UniProt entries by linking the GO terms present in the uncurated annotations with evidence text automatically extracted from the documents linked to UniProt entries. Platform: Online tool text mining, protein, gene ontology, annotation is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: UniProt
has parent organization: University of Lisbon; Lisbon; Portugal
European Union contract QLRI-1999-50595 PMID:17181854 Free for academic use nlx_149303 SCR_005792 2026-02-15 09:19:12 1
PolySearch
 
Resource Report
Resource Website
10+ mentions
PolySearch (RRID:SCR_005291) PolySearch service resource, analysis service resource, data analysis service, production service resource A web-based tool that supports more than 50 different classes of queries against nearly a dozen different types of text, scientific abstract or bioinformatic databases. The typical query supported by PolySearch is Given X, find all Y''s where X or Y can be diseases, tissues, cell compartments, gene/protein names, SNPs, mutations, drugs and metabolites. PolySearch also exploits a variety of techniques in text mining and information retrieval to identify, highlight and rank informative abstracts, paragraphs or sentences. text mining, disease, gene, protein, drug, metabolite, snp, gene sequence, pathway, tissue, gene family, subcellular localization, organ is listed by: OMICtools
has parent organization: University of Alberta; Alberta; Canada
OMICS_01194 SCR_005291 2026-02-15 09:19:03 20
GOanna
 
Resource Report
Resource Website
10+ mentions
GOanna (RRID:SCR_005684) GOanna service resource, analysis service resource, data analysis service, production service resource GOanna is used to find annotations for proteins using a similarity search. The input can be a list of IDs or it can be a list of sequences in FASTA format. GOanna will retrieve the sequences if necessary and conduct the specified BLAST search against a user-specified database of GO annotated proteins. The resulting file contains GO annotations of the top BLAST hits. The sequence alignments are also provided so the user can use these to access the quality of the match. Platform: Online tool agriculture, annotation, protein, ontology or annotation search engine, ontology or annotation editor is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: AgBase
USDA ;
Mississippi State University; Mississippi; USA ;
MSU Office of Research ;
MSU Bagley College of Engineering ;
MSU College of College of Veterinary Medicine ;
MSU Life Science and Biotechnology Institute
PMID:17135208
PMID:16961921
Free for academic use nlx_149139 SCR_005684 AgBase GOanna 2026-02-15 09:19:09 17
FuSSiMeG: Functional Semantic Similarity Measure between Gene-Products
 
Resource Report
Resource Website
FuSSiMeG: Functional Semantic Similarity Measure between Gene-Products (RRID:SCR_005738) FuSSiMeG service resource, analysis service resource, data analysis service, production service resource FuSSiMeG is being discontinued, may not be working properly. Please use our new tool ProteinOn. Functional Semantic Similarity Measure between Gene Products (FuSSiMeG) provides a functional similarity measure between two proteins using the semantic similarity between the GO terms annotated with the proteins. Platform: Online tool protein, similarity, gene ontology, gene, ontology, statistical analysis, term enrichment, semantic similarity, analysis, other analysis is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: ProteInOn
has parent organization: University of Lisbon; Lisbon; Portugal
Free for academic use nlx_149198 SCR_005738 Functional Semantic Similarity Measure between Gene-Products, Functional Semantic Similarity Measure between Gene Products (FuSSiMeG) 2026-02-15 09:19:03 0
I2D
 
Resource Report
Resource Website
10+ mentions
I2D (RRID:SCR_002957) I2D data analysis service, database, service resource, production service resource, data or information resource, analysis service resource Database of known and predicted mammalian and eukaryotic protein-protein interactions, it is designed to be both a resource for the laboratory scientist to explore known and predicted protein-protein interactions, and to facilitate bioinformatics initiatives exploring protein interaction networks. It has been built by mapping high-throughput (HTP) data between species. Thus, until experimentally verified, these interactions should be considered predictions. It remains one of the most comprehensive sources of known and predicted eukaryotic PPI. It contains 490,600 Source Interactions, 370,002 Predicted Interactions, for a total of 846,116 interactions, and continues to expand as new protein-protein interaction data becomes available. interaction, prediction, protein-protein interaction, high-throughput, model organism, mammal, eukaryote, visualization, interolog, protein is related to: Interaction Reference Index
is related to: IMEx - The International Molecular Exchange Consortium
is related to: PSICQUIC Registry
is related to: IntAct
has parent organization: University of Toronto; Ontario; Canada
National Science and Engineering Research Council RGPIN 203833-02;
NIGMS P50-GM62413
PMID:17535438
PMID:15657099
Free, Available for download, Freely available nif-0000-03005, r3d100010675 https://doi.org/10.17616/R3BG8R SCR_002957 Interologous Interaction Database, OPHID, I2D - Interologous Interaction Database 2026-02-15 09:18:25 23
Human Proteinpedia
 
Resource Report
Resource Website
10+ mentions
Human Proteinpedia (RRID:SCR_002948) Human Proteinpedia database, service resource, storage service resource, data repository, data or information resource A community portal for sharing and integration of human protein data that allows research laboratories to contribute and maintain protein annotations. The Human Protein Reference Database (HPRD) integrates data that is deposited along with the existing literature curated information in the context of an individual protein. Data pertaining to post-translational modifications, protein-protein interactions, tissue expression, expression in cell lines, subcellular localization and enzyme substrate relationships can be submitted. enzyme, protein expression, post-translational modification, protein-protein interaction, subcellular localization, enzyme substrate, tissue expression, protein, protein binding, peptide, mass spectrometry, mass spectrometry spectra, immunohistochemistry, western blotting, microarray, co-immunoprecipitation, fluorescence, annotation, cell line expression, disease tissue expression, FASEB list is listed by: re3data.org
is related to: HPRD - Human Protein Reference Database
has parent organization: Johns Hopkins University; Maryland; USA
has parent organization: Institute of Bioinformatics; Bangalore; India
PMID:18259167 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02999, r3d100010985 https://doi.org/10.17616/R3V62C SCR_002948 2026-02-15 09:18:25 32
FunSimMat
 
Resource Report
Resource Website
1+ mentions
FunSimMat (RRID:SCR_002729) FunSimMat data analysis service, database, software resource, data access protocol, web service, service resource, production service resource, data or information resource, analysis service resource FunSimMat is a comprehensive resource of semantic and functional similarity values. It allows ranking disease candidate proteins for OMIM diseases and searching for functional similarity values for proteins (extracted from UniProt), and protein families (Pfam, SMART). FunSimMat provides several different semantic and functional similarity measures for each protein pair using the Gene Ontology annotation from UniProtKB and the Gene Ontology Annotation project at EBI (GOA). There are several search options available: Disease candidate prioritization: * Rank candidate proteins using any OMIM disease entry * Compare a list of proteins to any OMIM disease entry * Compare all human proteins to any OMIM disease entry Functional similarity: * Compare one protein / protein family to a list of proteins / protein families * Compare a list of GO terms to a list of proteins / protein families Semantic similarity: * For a list of GO terms, FunSimMat performs an all-against-all comparison and displays the semantic similarity values. FunSimMat provides an XML-RPC interface for performing automatic queries and processing of the results as well as a RestLike Interface. Platform: Online tool functional similarity value, protein family, protein similarity, semantic similarity value, similarity value, functional similarity, disease gene candidate prioritization, disease, protein, protein family, disease candidate prioritization, semantic similarity, gene ontology, visualization, annotation, database or data warehouse is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Max-Planck-Institute for Informatics; Saarbrucken; Germany
German National Genome Research Network 01GR0453;
Klinische Forschergruppe KFO 129/1-1;
Klinische Forschergruppe KFO 129/1-2;
European Union LSHG-CT-2003-503265
PMID:19923227
PMID:17932054
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02860 SCR_002729 FunSimMat - Functional Similarity Matrix 2026-02-15 09:18:22 1
Computational Biology Center
 
Resource Report
Resource Website
50+ mentions
Computational Biology Center (RRID:SCR_002877) portal, training resource, data or information resource, topical portal, disease-related portal Computational biology research at Memorial Sloan-Kettering Cancer Center (MSKCC) pursues computational biology research projects and the development of bioinformatics resources in the areas of: sequence-structure analysis; gene regulation; molecular pathways and networks, and diagnostic and prognostic indicators. The mission of cBio is to move the theoretical methods and genome-scale data resources of computational biology into everyday laboratory practice and use, and is reflected in the organization of cBio into research and service components ~ the intention being that new computational methods created through the process of scientific inquiry should be generalized and supported as open-source and shared community resources. Faculty from cBio participate in graduate training provided through the following graduate programs: * Gerstner Sloan-Kettering Graduate School of Biomedical Sciences * Graduate Training Program in Computational Biology and Medicine Integral to much of the research and service work performed by cBio is the creation and use of software tools and data resources. The tools that we have created and utilize provide evidence of our involvement in the following areas: * Cancer Genomics * Data Repositories * iPhone & iPod Touch * microRNAs * Pathways * Protein Function * Text Analysis * Transcription Profiling drug, evolution, experiment, gene, algorithm, bioinformatics, biology, cancer, clinical, computational, diagnostic, genome, human, initiation, kinetics, laboratory, leukemia, ligand, metastasis, microrna, mirna, model, molecular, network, pathway, phenotype, prognostic, progression, protein, regulation, research, resistance, rna, sequence, stem cell, structure, t cell, therapy, treatment, tumor is parent organization of: TMBETA-GENOME- Annotation of Beta-Barrel Membrane Proteins in Genomic Sequences Free, Freely available nif-0000-25560 SCR_002877 cBio 2026-02-15 09:18:25 70
Tuschl Laboratory: RNA Molecular Biology
 
Resource Report
Resource Website
1+ mentions
Tuschl Laboratory: RNA Molecular Biology (RRID:SCR_002866) organization portal, data or information resource, laboratory portal, portal RNA is not only a carrier of genetic information, but also a catalyst and a guide for sequence-specific recognition and processing of other RNA molecules. This lab investigates the regulatory mechanisms of RNA interference, RNA-mediated translational control, and nuclear pre-mRNA splicing. Classical and combinatorial biochemical techniques are used to analyze the function of the RNA- and protein-components involved in those processes. genetics, biochemical, biology, catalyst, mechanism, mirna, molecule, process., protein, regulation, rna, sequence, sirna, technique has parent organization: Rockefeller University; New York; USA Free, Freely available nif-0000-25546 http://www.rockefeller.edu/labheads/tuschl/sirna.html SCR_002866 Tuschl Lbaoratory 2026-02-15 09:18:24 5
PredictNLS
 
Resource Report
Resource Website
10+ mentions
PredictNLS (RRID:SCR_003133) PredictNLS data analysis service, software resource, service resource, production service resource, analysis service resource Software automated tool for analysis and determination of Nuclear Localization Signals (NLS). Predicts that your protein is nuclear or finds out whether your potential NLS is found in our database. The program also compiles statistics on the number of nuclear/non-nuclear proteins in which your potential NLS is found. Finally, proteins with similar NLS motifs are reported, and the experimental paper describing the particular NLS are given. bio.tools, nuclear localization signal, protein, protein sequence is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: ROSTLAB
has parent organization: Columbia University; New York; USA
DOI:10.1093/embo-reports/kvd092 Free, Available for download, Freely available nif-0000-31416, OMICS_01633, SCR_008553, biotools:predictnls https://www.rdocumentation.org/packages/propagate/versions/1.0-4/topics/predictNLS SCR_003133 Prediction and Analysis of Nuclear Localization Signals 2026-02-15 09:18:27 30

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