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https://edspace.american.edu/openbehavior/project/open-ephys/

Organization mission is to advance understanding of brain by promoting community ownership of neuroscience tools.Collaborative effort to develop, document, and distribute open source tools for systems neuroscience.Project aims to distribute reliable open source software as well as tools for extracellular recording and stimulation.

Proper citation: Open Ephys (RRID:SCR_021624) Copy   

•   Source: SciCrunch Registry

https://github.com/DepartmentofNeurophysiology/Matlab-Whisker-Tracker

Shared database of videos featuring juvenile and adult male rats and adult male mice exploring stationary objects.This dataset includes wide variety of experimental conditions including genetic, pharmacological, and sensory deprivation interventions to explore how active sensing behavior is modulated by different factors. Database of high speed videos of whisking behavior in freely moving rodents.Open source high speed infrared videography database to study principles of active sensing in freely navigating rodents.

Proper citation: Open Source Whisking Video Database (RRID:SCR_021407) Copy   

•   Source: SciCrunch Registry

https://www.eneuro.org/content/12/2/ENEURO.0444-24.2025

Low-cost implant for reliable diaphragm EMG recordings in awake, behaving rats.Diaphragm EMG implant.

Proper citation: Implant for Reliable Diaphragm EMG Recordings in Awake, Behaving Rats (RRID:SCR_026968) Copy   

•   Source: SciCrunch Registry

https://edspace.american.edu/openbehavior/project/ort/

Open-source apparatus to enable continuous individual monitoring, training, and testing of rats without removing them from their social environment. This system utilizes RFID technology to track individual animals, minimizing human intervention and providing precise behavioral data.

Proper citation: One-rat Turnstile (RRID:SCR_025570) Copy   

•   Source: SciCrunch Registry

https://github.com/BadenLab/LED-Zappelin

Open source LED controller for arbitrary spectrum visual stimulation and optogenetics during 2 photon imaging. Device that rapidly time interleaves stimulation and detection epochs during two photon imaging.

Proper citation: LED Zappelin’ (RRID:SCR_022560) Copy   

•   Source: SciCrunch Registry

https://github.com/ntorquet/lmt_toolkit_analysis

Open source web application created to analyze Live Mouse Tracker data easily and intuitively. Used to check reliability and to make some analysis of data from Live Mouse Tracker experiments. LMT stores data in SQLite files that requires some computer skills, but LMT-toolkit makes it easy to compute and extract behavioral profiles for each animal tested following step-by-step process.

Proper citation: Live Mouse Tracker Toolkit Analysis (RRID:SCR_024592) Copy   

•   Source: SciCrunch Registry

https://www.dropbox.com/s/wx7aicjh4is81om/HomeCageForelimbTask.py?dl=0

Software Python tool running on Raspberry Pi computer. Used for trial timing and data logging. Part of Autonomous Training of Forelimb Motor Task system.

Proper citation: Autonomous Training of a Forelimb Motor Task (RRID:SCR_021603) Copy   

•   Source: SciCrunch Registry

https://github.com/mauriciowr/OBAT

Software tool as part of Operant Box for Auditory Tasks system.

Proper citation: Operant Box for Auditory Tasks (RRID:SCR_021604) Copy   

•   Source: SciCrunch Registry

https://github.com/MaSoMoTr/MaSoMoTr

Markerless video-based tool to simultaneously track two interacting mice of the same appearance in controlled settings for quantifying behaviors such as different types of sniffing, touching, and locomotion to improve tracking accuracy under these settings without increased human effort. It incorporates conventional handcrafted tracking and deep-learning-based techniques. The tool is trained on small number of manually annotated images from basic experimental setup and outputs body masks and coordinates of the snout and tail-base for each mouse.

Proper citation: Markerless Mouse Tracking for Social Experiments (RRID:SCR_025368) Copy   

•   Source: SciCrunch Registry

https://github.com/PTMonteiro/GoFish_Ajuwon_etal_2022

Bonsai code for running GOFish platform for behavioural experiments in fish.

Proper citation: GoFish Ajuwon etal 2022 (RRID:SCR_022511) Copy   

•   Source: SciCrunch Registry

https://github.com/mmgxw3/pipetteFindingCNN

Software application for convolutional neural network that assesses pipette positioning before patch clamp is begun to minimize patch clamping errors in electrophysiology experiments. Used for detecting pipette positioning and making patch clamping procedures.

Proper citation: Pipette Finding CNN (RRID:SCR_024992) Copy   

•   Source: SciCrunch Registry

https://github.com/ZuAh/Custom-fitting-of-implants

Tutorial to custom-design and -fit implants to continuous and discontinuous skull surfaces. Universal Guide for Skull Extraction and Custom-Fitting of Implants to Continuous and Discontinuous Skulls.

Proper citation: Custom-fitting-of-implants (RRID:SCR_025270) Copy   

•   Source: SciCrunch Registry

https://github.com/NeLy-EPFL/LiftPose3D

Software tool for transforming 2D poses to 3D coordinates on labaratory animals. Used for kinematic studies of laboratory animals. Tracking movements in three dimensions from behaving flies, mice, rats, and non-human primates.

Proper citation: LiftPose3D (RRID:SCR_023049) Copy   

•   Source: SciCrunch Registry

https://m3platform.weebly.com/

Software neuroscience laboratory environment for simultaneous neuronal imaging and behavioral monitoring. McGill-Mouse-Miniscope Touchscreen Behavior Platform. Standardized approach for high throughput imaging of neuronal dynamics during behavior.

Proper citation: M3 Platform (RRID:SCR_023425) Copy   

•   Source: SciCrunch Registry

https://github.com/WinterLab-Berlin/LabNet

Open source software for parallel control over multiple behavioral systems.C++ optimized control layer software to give access to Raspberry Pi connected hardware. Suitable for time critical operations, and to be simple to expand. Used for general automation in experimental laboratories with its control PC located at some distance.

Proper citation: LabNet (RRID:SCR_023712) Copy   

•   Source: SciCrunch Registry

https://github.com/oculomatic/oculomatic-release

Software tool for high speed eye tracking for Point Gray USB3.0 cameras.Oculomatic software tracks eye position within acquired image frame at frame rate dictated by image sensor.

Proper citation: Oculomatic (RRID:SCR_021525) Copy   

•   Source: SciCrunch Registry

https://github.com/AdaptiveMotorControlLab/Camera_Control

Open source software package that allows video to be recorded in sync with behavior. Python GUI and scripts allows investigators to record from multiple imaging source camera feeds with associated timestamps for each frame. Python API to record video system timestamps from Imaging Source USB cameras. Package requires Windows 10, Anaconda, and Git, and is compatible with Imaging Source USB3 cameras. Part of Camera Control project.

Proper citation: Camera Control (RRID:SCR_021614) Copy   

•   Source: SciCrunch Registry

https://github.com/jellen44/AutomaticSleepScoringTool

Software pipeline for sleep researchers to perform automatic sleep scoring for rodents. Artificial neural network for automated behavioral state classification in rats.

Proper citation: AutomaticSleepScoringTool (RRID:SCR_022300) Copy   

•   Source: SciCrunch Registry

https://github.com/haiderlab/DP-Lick-Detector

Distribution package for Dual Port Lick Detector.Package includes files relevant to building lick detector.

Proper citation: Dual Port Lick Detector (RRID:SCR_021521) Copy   

•   Source: SciCrunch Registry

https://github.com/wildrootlab/SHARCQ

Software tools to register histological section images and cell count locations to mouse brain atlas. Semi automated workflow and GUI for automated brain slice histology alignment, registration, and cell quantification. Used to explore Allen Mouse Brain Atlas, register asymmetric slice images to atlas using manual input, and analyze region of interest data by registering locations of fluorescently labeled cells to standardized regions of Atlas.

Proper citation: SHARCQ (RRID:SCR_022498) Copy   

•   Source: SciCrunch Registry