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Memorial Sloan Kettering Cancer Center Mouse Genetics Core Facility (RRID:SCR_027803)Copy Citation Copied
URL: https://www.mskcc.org/research/ski/core-facilities/mouse-genetics
Proper Citation: Memorial Sloan Kettering Cancer Center Mouse Genetics Core Facility (RRID:SCR_027803)
Description: Core facilitates the use of mouse molecular genetics at MSK for in vivo studies of gene functions germane to cancer. Provides expertise in generation and effective use of genetically engineered mouse (GEM) models—namely, molecular and cell biology, embryo micromanipulation, and reproductive biology. Molecular and cellular biology services cover design and assembly of genome engineering reagents, such as donor transgenes and CRISPR/Cas9; performing all aspects of gene targeting in mouse embryonic stem (ES) cells; identification and verification of alleles carried by a generated GEM model; and establishment of new ES cells from a variety of GEM lines. Provides consultation and training for the design and production of GEM models, ES cell culture and manipulation, and mouse reproduction and genetic crosses.
Resource Type: service resource, access service resource, core facility
Keywords: ABRF, Molecular and cellular biology services, mouse molecular genetics, genetically engineered mouse models,
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