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Icahn School of Medicine at Mount Sinai Stem Cell Engineering Core Facility (RRID:SCR_027503)Copy Citation Copied
URL: https://icahn.mssm.edu/research/resources/deans-cores/stem-cell-engineering
Proper Citation: Icahn School of Medicine at Mount Sinai Stem Cell Engineering Core Facility (RRID:SCR_027503)
Description: Core provides services for generation and characterization of induced pluripotent stem cells (iPSCs) from somatic sources such as blood and fibroblasts, along with long-term cryobanking. Offers access to collection of well-characterized iPSC lines derived from both healthy donors and patients with various diseases, representing a range of ethnic backgrounds and sexes.Major focus of core is gene editing in pluripotent stem cells, with expertise in CRISPR-based applications from precise point mutation knock-in (correction or introduction) to the generation of reporter lines (e.g., GFP and other fluorescent reporters) and inducible systems such as Cre-lox, dTAG, and beyond.Core provides guidance and support for the differentiation of iPSCs into multiple cell types, using both monolayer and 3D organoid formats, enabling downstream disease modeling and functional studies.
Synonyms: , Stem Cell Engineering Core, Icahn School of Medicine at Mount Sinai Stem Cell Engineering Core
Resource Type: service resource, access service resource, core facility
Keywords: ABRF, generation and characterization of induced pluripotent stem cells, blood, fibroblasts, cryobanking
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