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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Simpleaffy
 
Resource Report
Resource Website
50+ mentions
Simpleaffy (RRID:SCR_001302) Simpleaffy data analysis software, software resource, data processing software, software application Software package that provides high level functions for reading Affy .CEL files, phenotypic data, and then computing simple things with it, such as t-tests, fold changes and the like. It makes heavy use of the affy library. It also has some basic scatter plot functions and mechanisms for generating high resolution journal figures. affymetrix, annotation, data import, differential expression, microarray, one channel, preprocessing, quality control, report writing, transcription, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:16076888 GNU General Public License, v2 or newer OMICS_02034 SCR_001302 Simpleaffy - Very simple high level analysis of Affymetrix data 2026-02-13 10:54:49 85
rMAT
 
Resource Report
Resource Website
10+ mentions
rMAT (RRID:SCR_001583) data processing software, data analysis software, source code, software application, software resource Software package for normalizing and analyzing tiling arrays and ChIP-chip data. It is the R-version of a MAT program. chip-seq, normalize data, tiling array, mat, r is listed by: OMICtools
has parent organization: Bioconductor
PMID:20089513 Free, Available for download, Freely available OMICS_00810 http://www.rglab.org SCR_001583 2026-02-13 10:54:53 16
CGHcall
 
Resource Report
Resource Website
10+ mentions
CGHcall (RRID:SCR_001578) data analysis software, software resource, data processing software, software application Software that calls aberrations for array CGH data using a six state mixture model and several biological concepts. It is written in R. cgh data analysis, objective classification, data aberration is listed by: OMICtools
is hosted by: Bioconductor
Free, Available for download, Freely available OMICS_00709 SCR_001578 2026-02-13 10:54:52 30
SPADE
 
Resource Report
Resource Website
100+ mentions
SPADE (RRID:SCR_001810) data visualization software, data processing software, data analysis software, software application, software resource An analysis and visualization software tool for high dimensional flow cytometry data that organizes cells into hierarchies of related phenotypes. software package, mac os x, unix/linux, windows, r, clustering, flow cytometry, gui, graph, network, visualization is listed by: OMICtools
has parent organization: Bioconductor
is a plug in for: FlowJo
PMID:21964415 Free, Available for download, Freely available OMICS_05639 http://cytospade.org/ http://www.bioconductor.org/packages/release/bioc/html/spade.html SCR_001810 Spanning tree Progression of Density normalized Events, SPADE - An analysis and visualization tool for Flow Cytometry 2026-02-13 10:54:55 275
SeqGSEA
 
Resource Report
Resource Website
10+ mentions
SeqGSEA (RRID:SCR_005724) SeqGSEA data analysis software, software resource, data processing software, software application Software package that provides methods for gene set enrichment analysis of high-throughput RNA-Seq data by integrating differential expression and splicing. It uses negative binomial distribution to model read count data, which accounts for sequencing biases and biological variation. Based on permutation tests, statistical significance can also be achieved regarding each gene''s differential expression and splicing, respectively. differential expression, gene expression, gene set enrichment, rna-seq, sequencing, splicing is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v3 or newer OMICS_02251 SCR_005724 SeqGSEA - Gene Set Enrichment Analysis (GSEA) of RNA-Seq Data: integrating differential expression and splicing 2026-02-13 10:55:41 34
DESeq
 
Resource Report
Resource Website
100+ mentions
DESeq (RRID:SCR_000154) DESeq data analysis software, software resource, data processing software, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30,2023. Software for differential gene expression analysis based on the negative binomial distribution. It estimates variance-mean dependence in count data from high-throughput sequencing assays and tests for differential expression. gene expression, binomial, differential, negative binomial distribution, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is hosted by: Bioconductor
PMID:20979621
DOI:10.1186/s13059-014-0550-8
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01306, biotools:deseq https://bio.tools/deseq
https://sources.debian.org/src/r-bioc-deseq2/
SCR_000154 2026-02-13 10:54:37 473
Qvalue
 
Resource Report
Resource Website
10+ mentions
Qvalue (RRID:SCR_001073) data analysis software, software resource, data processing software, software application R package that takes a list of p-values resulting from the simultaneous testing of hypotheses and estimates their q-values. It is designed to measure the proportion of false positives when a test is significant. The software is capable of generating plots for visualization. It can be applied to problems in genomics, brain imaging, astrophysics, and data mining. p value, false positive, null hypothesis, genomics, brain imaging, astrophysics, data mining, r, visualization is listed by: OMICtools
is hosted by: Bioconductor
Free, Available for download, Freely available OMICS_00624 https://github.com/jdstorey/qvalue SCR_001073 2026-02-13 10:54:47 31
MetaCyto
 
Resource Report
Resource Website
1+ mentions
MetaCyto (RRID:SCR_016415) data processing software, data analysis software, software toolkit, software application, software resource Software tool for automated meta-analysis of mass and flow cytometry data. Provides functions for preprocessing, automated gating and meta-analysis of cytometry data and collection of cytometry data from the ImmPort database. automated, analysis, meta, flow, cytometry, data, bio.tools is listed by: Bioconductor
is listed by: NIDDK Information Network (dkNET)
is listed by: bio.tools
is listed by: Debian
is related to: The Immunology Database and Analysis Portal (ImmPort)
the National Institute of Allergy and Infectious Diseases HHSN272201200028C Free, Available for download, Freely available biotools:metacyto https://bio.tools/metacyto SCR_016415 2026-02-13 10:57:48 5
clusterProfiler
 
Resource Report
Resource Website
10000+ mentions
clusterProfiler (RRID:SCR_016884) data visualization software, data processing software, data analysis software, software application, software resource Software R package for statistical analysis and visualization of functional profiles for genes and gene clusters. data, statistical, analysis, visualization, gene, cluster, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
National 973 Projects of China ;
2007 Chang-Jiang Scholars Program ;
National Natural Science Foundation of China ;
Guangdong Natural Science Research Grant ;
Fundamental Research Funds for the Central Universities
PMID:22455463 Free, Available for download, Freely available biotools:clusterprofiler https://github.com/GuangchuangYu/clusterProfiler
https://guangchuangyu.github.io/software/clusterProfiler/
https://bio.tools/clusterprofiler
SCR_016884 Cluster Profiler 2026-02-13 10:57:53 10762
RnaSeqGeneEdgeRQL
 
Resource Report
Resource Website
RnaSeqGeneEdgeRQL (RRID:SCR_016699) data processing software, data analysis software, software toolkit, software application, software resource Software to study analysis of an RNA-Seq experiment using the Rsubread and edgeR packages. The workflow starts from read alignment and continues on to data exploration, to differential expression and, finally, to pathway analysis. The analysis includes plots, GO and KEGG analyses, and the analysis of a expression signature as generated by a prior experiment. study, analysis, RNA, sequencing, read, alignment, data is affiliated with: Bioconductor Free, Available for download, Freely available SCR_016699 2026-02-13 10:57:51 0
GAGE
 
Resource Report
Resource Website
50+ mentions
GAGE (RRID:SCR_017067) data analysis software, software resource, data processing software, software application Software R package for gene set enrichment or pathway analysis. Applicable independent of microarray or RNAseq data attributes including sample sizes, experimental designs, assay platforms, and other types of heterogeneity. Pipeline routines of multiple GAGE analyses in batch, comparison between parallel analyses, and combined analysis of heterogeneous data from different sources and studies. gene, set, enrichment, pathway, batch, comparison, parallel, analysis, heterogeneous, data is listed by: Bioconductor
is related to: R Project for Statistical Computing
Free, Available for download, Freely available SCR_017067 Generally Applicable Gene-set Enrichment for pathway analysis, gage, Generally Applicable Gene-set Enrichment, GSEA 2026-02-13 10:57:50 50
affydata
 
Resource Report
Resource Website
affydata (RRID:SCR_016976) AffyData data processing software, data or information resource, data analysis software, software application, software resource Software R package for analysis of Affymetrix Data. Contains samples data files of a large size. analysis, Affymetrix, data, large, dataset, oligonucleotide, array is listed by: Bioconductor
is related to: affy
is related to: R Project for Statistical Computing
Free, Available for download, Freely available SCR_016976 affydata, Affymetrix Data, Affymetrix Data for Demonstration Purpose 2026-02-13 10:57:54 0
Bioconductor mailing list
 
Resource Report
Resource Website
1+ mentions
Bioconductor mailing list (RRID:SCR_012915) Bioconductor mailing list data or information resource, narrative resource, listserv, feed This mailing list is for announcements about Bioconductor and the availability of new code and questions and answers about problems and solutions using Bioconductor. is listed by: OMICtools
has parent organization: Bioconductor
OMICS_01705 SCR_012915 2026-02-13 10:57:02 2
minfi
 
Resource Report
Resource Website
100+ mentions
minfi (RRID:SCR_012830) minfi data visualization software, data processing software, data analysis software, software application, software resource Software tools for analyzing and visualizing Illumina''s 450k array data. Illumina, array data, Analyze Illumina Infinium DNA methylation arrays, DNA methylation array, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: SWAN
has parent organization: Bioconductor
PMID:28035024 Free, Available for download, Freely available biotools:minfi, OMICS_00799, BioTools:minfi https://bio.tools/minfi
https://bio.tools/minfi
https://bio.tools/minfi
SCR_012830 2026-02-13 10:57:02 390
affy
 
Resource Report
Resource Website
1000+ mentions
affy (RRID:SCR_012835) Affy data analysis software, software resource, data processing software, software application Software R package of functions and classes for the analysis of oligonucleotide arrays manufactured by Affymetrix. Used to process probe level data and for exploratory oligonucleotide array analysis. analysis, oligonucleotide, array, Affymetrix, process, probe, data, function, bio.tools is listed by: OMICtools
is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: affydata
is related to: R Project for Statistical Computing
is related to: OMICtools
Danish Biotechnology Instrument Center PMID:14960456 Free, Available for download, Freely available BioTools:affy, OMICS_00740, biotools:affy https://bio.tools/affy
https://sources.debian.org/src/r-bioc-affy/
SCR_012835 Affymetrix, analysis of Affymetrix GeneChip data at the probe level, analysis of Affymetrix GeneChip data 2026-02-13 10:57:01 2996
edgeR
 
Resource Report
Resource Website
10000+ mentions
edgeR (RRID:SCR_012802) edgeR data analysis software, software resource, data processing software, software application Bioconductor software package for Empirical analysis of Digital Gene Expression data in R. Used for differential expression analysis of RNA-seq and digital gene expression data with biological replication. empirical, analysis, digital, gene, expression, data, R, RNA-seq data, bio.tools is used by: Glimma
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: SARTools
is related to: Bioconductor
works with: tximport
NHMRC 406657;
Independent Research Institutes Infrastructure Support Scheme 361646;
Victorian State Government OIS grant ;
Melbourne International Research Scholarship ;
Harris and IBS Honours scholarships
PMID:19910308
DOI:10.1093/bioinformatics/btp616
Free, Available for download, Freely available OMICS_01308, biotools:edger https://bio.tools/edger
https://sources.debian.org/src/r-bioc-edger/
SCR_012802 edgeR, empirical analysis of digital gene expression data in R, Empirical analysis of Digital Gene Expression data in R 2026-02-13 10:57:01 21899
MSstats
 
Resource Report
Resource Website
100+ mentions
MSstats (RRID:SCR_014353) data analysis software, software resource, data processing software, software application A package for statistical relative quantification of proteins and peptides in global, targeted, and data-independent proteomics. It handles shotgun, label-free, and label-based Selected Reaction Monitoring, as well as SWATH/DIA (Data Independent Acquisition) experiments. MSStats provide functionality for data processing and visualization, model-based statistical analysis, and model-based sample size calculations. data independent acquisition, statistical relative quantification, protein, peptide, data analysis software, data processing, data visualization, proteomics uses: R Project for Statistical Computing
is used by: Skyline
is listed by: Bioconductor
National Science Foundation CAREER award 1054826 DOI:10.1186/1471-2105-13-S16-S6 Acknowledgement requested, Available for download http://www.bioconductor.org/packages/release/bioc/html/MSstats.html SCR_014353 MSStats 2026-02-13 10:57:17 214
LIMMA
 
Resource Report
Resource Website
10000+ mentions
LIMMA (RRID:SCR_010943) LIMMA data analysis software, software resource, data processing software, software application Software package for the analysis of gene expression microarray data, especially the use of linear models for analyzing designed experiments and the assessment of differential expression. analysis, gene, expression, microarray, data, linear, model, bio.tools is used by: Glimma
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: GEO2R
is related to: Bioconductor
Free, Available for download, Freely available biotools:limma, OMICS_00769 https://omictools.com/limma-tool
https://bio.tools/limma
https://sources.debian.org/src/r-bioc-limma/
SCR_010943 Linear Models for Microarray Data 2026-02-13 10:56:42 24583
scTHI
 
Resource Report
Resource Website
1+ mentions
scTHI (RRID:SCR_018918) scTHI data analysis software, software resource, data processing software, software application Software R package to identify active pairs of ligand receptors from single cells in order to study,among others, tumor host interactions. Contains set of signatures to classify cells from tumor microenvironment. Ligand receptor, active pair, active pair ligand receptor, single cell, tumor interaction, tumor microenvironment, cells clasification is listed by: Bioconductor Free, Available for download, Freely available SCR_018918 2026-02-13 10:58:19 1
variancePartition
 
Resource Report
Resource Website
50+ mentions
variancePartition (RRID:SCR_019204) data processing software, data analysis software, data analytics software, software application, software resource Software R package to quantify and interpret divers of variation in multilevel gene expression experiments.Provides statistical and visualization framework for studying drivers of variation in RNA-seq datasets in many types of high throughput genomic assays including RNA-seq gene-, exon- and isoform-level quantification, splicing efficiency, protein quantification, metabolite quantification, metagenomic assays, methylation arrays and epigenomic sequencing assays. Repeated measures, variation in gene expression, RNA-seq datasets, high throughput genomic assays, splicing efficiency, protein quantification, metabolite quantification, metagenomic assays, methylation arrays, epigenomic sequencing assays, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is related to: CRAN
NHLBI U01 HL107388;
Icahn School of Medicine at Mount Sinai
PMID:27884101 Free, Available for download, Freely available biotools:variancepartition https://bio.tools/variancepartition SCR_019204 2026-02-13 10:58:25 52

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