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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MicrobesOnline
 
Resource Report
Resource Website
100+ mentions
MicrobesOnline (RRID:SCR_005507) MicrobesOnline data analysis service, analysis service resource, data or information resource, production service resource, source code, service resource, software resource, database MicrobesOnline is designed specifically to facilitate comparative studies on prokaryotic genomes. It is an entry point for operon, regulons, cis-regulatory and network predictions based on comparative analysis of genomes. The portal includes over 1000 complete genomes of bacteria, archaea and fungi and thousands of expression microarrays from diverse organisms ranging from model organisms such as Escherichia coli and Saccharomyces cerevisiae to environmental microbes such as Desulfovibrio vulgaris and Shewanella oneidensis. To assist in annotating genes and in reconstructing their evolutionary history, MicrobesOnline includes a comparative genome browser based on phylogenetic trees for every gene family as well as a species tree. To identify co-regulated genes, MicrobesOnline can search for genes based on their expression profile, and provides tools for identifying regulatory motifs and seeing if they are conserved. MicrobesOnline also includes fast phylogenetic profile searches, comparative views of metabolic pathways, operon predictions, a workbench for sequence analysis and integration with RegTransBase and other microbial genome resources. The next update of MicrobesOnline will contain significant new functionality, including comparative analysis of metagenomic sequence data. Programmatic access to the database, along with source code and documentation, is available at http://microbesonline.org/programmers.html. microbe, genome, bacteria, archaea, fungi, prokaryote, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: Lawrence Berkeley National Laboratory
DOE DE-AC02-05CH11231 PMID:19906701 nlx_144607, biotools:microbesonline https://bio.tools/microbesonline SCR_005507 Microbial Genomics Database, Microbes Online 2026-02-14 02:00:55 156
DiProGB
 
Resource Report
Resource Website
1+ mentions
DiProGB (RRID:SCR_005651) DiProGB software resource Genome browser that encodes the genome sequence by physico-chemical dinucleotide properties such as stacking energy, melting temperature or twist angle. Analyses can be performed for the + and ?, as well as for the double strand. genome, browser, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Dinucleotide Property Database
PMID:19605418 Free, Freely available biotools:diprogb, OMICS_00880 https://bio.tools/diprogb SCR_005651 DiProGB - The Dinucleotide Properties Genome Browser, Dinucleotide Properties Genome Browser 2026-02-14 02:00:58 4
Bambino
 
Resource Report
Resource Website
1+ mentions
Bambino (RRID:SCR_005649) Bambino data analysis service, analysis service resource, production service resource, service resource, software resource A variant detector and graphical alignment viewer for next-generation sequencing data in the SAM/BAM format, which is capable of pooling data from multiple source files. Bambino may be launched online via Java Web Start or downloaded and run locally. java, next-generation sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: National Cancer Institute
PMID:21278191 Https://cgwb.nci.nih.gov/goldenPath/bamview/documentation/Bambino_Click-thru-agreement-for-executable_final.txt OMICS_00876, biotools:bambino https://bio.tools/bambino SCR_005649 Bambino: a variant detector and alignment viewer for next-generation sequencing data in the SAM/BAM format 2026-02-14 02:00:56 5
BS Seeker
 
Resource Report
Resource Website
1+ mentions
BS Seeker (RRID:SCR_005641) sequence analysis software, data processing software, data analysis software, software application, software resource Software which performs accurate and fast mapping of bisulfite-treated short reads. Supplementary information and examples are provided on the site. bisulfite sequencing, sequence analysis software, short read, sequence mapping, bio.tools uses: Bowtie
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Bs-Seeker2
has parent organization: University of California at Los Angeles; California; USA
PMID:20416082 Free, Available for download, Freely available OMICS_00578, biotools:bs_seeker https://bio.tools/bs_seeker SCR_005641 Bisulfite Sequence Seeker 2026-02-14 02:00:58 3
DMRforPairs
 
Resource Report
Resource Website
1+ mentions
DMRforPairs (RRID:SCR_005702) software resource Software for identifying differentially methylated regions between unique samples using array based methylation profiles. It allows researchers to compare n greater than or equal to 2 unique samples with regard to their methylation profile. The (pairwise) comparison of n unique single samples distinguishesit from other existing pipelines as these often compare groups of samples in either single CpG locus or region based analysis. DMRforPairs defines regions of interest as genomic ranges with sufficient probes located in close proximity to each other. Probes in one region are optionally annotated to the same functional class(es). Differential methylation is evaluated by comparing the methylation values within each region between individual samples and (if the difference is sufficiently large), testing this difference formally for statistical significance. standalone software, mac os x, unix/linux, windows, r, annotation, dna methylation, differential methylation, microarray, report writing, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24884391 GNU General Public License, v2 or greater biotools:dmrforpairs, OMICS_04059 https://bio.tools/dmrforpairs SCR_005702 DMR2+, DMRforPairs: identifying Differentially Methylated Regions between unique samples using array based methylation profiles 2026-02-14 02:01:09 4
Bismark
 
Resource Report
Resource Website
1000+ mentions
Bismark (RRID:SCR_005604) Bismark software resource Software tool to map bisulfite converted sequence reads and determine cytosine methylation states. Flexible aligner and methylation caller for Bisulfite-Seq applications. Used to map bisulfite treated sequencing reads to genome of interest and perform methylation calls in single step. Map bisulfite treated sequence reads, determine cytosine methylation states, genome, sequence reads, perform methylation calls, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Babraham Institute
PMID:21493656
DOI:10.1093/bioinformatics/btr167
Free, Available for download, Freely available biotools:bismark, OMICS_00575 https://github.com/FelixKrueger/Bismark
https://bio.tools/bismark
https://sources.debian.org/src/bismark/ SCR_005604 2026-02-14 02:01:09 1123
TMAJ
 
Resource Report
Resource Website
10+ mentions
TMAJ (RRID:SCR_005601) TMAJ software resource Open-source software to support information and images related to tissue micro-arrays. It contains support for multiple organ systems, multiple users, image analysis, and is designed to be compliant with HIPPA regulations. Patients, specimens, blocks, slides, cores, images, and scores can all be stored and viewed. Features include advanced security, custom dynamic fields, and an image analysis program. tissue microarray, java, java swing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Johns Hopkins University; Maryland; USA
has parent organization: SourceForge
GNU General Public License, v3 biotools:tmaj, OMICS_00823 https://bio.tools/tmaj SCR_005601 TMAJ Software Project 2026-02-14 02:00:56 10
GoFish
 
Resource Report
Resource Website
1+ mentions
GoFish (RRID:SCR_005682) GoFish data analysis service, analysis service resource, production service resource, source code, service resource, software resource Software program, available as a Java applet online or to download, allows the user to select a subset of Gene Ontology (GO) attributes, and ranks genes according to the probability of having all those attributes., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, ontology or annotation browser, java, windows, mac os x, linux, unix, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: University of Toronto; Ontario; Canada
has parent organization: Harvard Medical School; Massachusetts; USA
Aventis Pharmaceuticals ;
Howard Hughes Medical Institute ;
NHGRI
PMID:12691998 THIS RESOURCE IS NO LONGER IN SERVICE biotools:gofish, nlx_149126, OMICS_02272 http://llama.mshri.on.ca/Software.html
https://bio.tools/gofish
SCR_005682 2026-02-14 02:01:08 1
Maqview
 
Resource Report
Resource Website
Maqview (RRID:SCR_005632) MaqView data visualization software, software resource, data processing software, software application A graphical read alignment viewer specifically designed for the Maq alignment file and allows you to see the mismatches, base qualities and mapping qualities. It is highly efficient in speed, memory and disk usage. Maqview is based on OpenGL and is known to work on both Mac OS X and Linux. Porting to Windows is in principle easy. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
DOI:10.1101/gr.078212.108 GNU General Public License OMICS_00889, biotools:maqview https://bio.tools/maqview
https://sources.debian.org/src/maqview/
SCR_005632 Mapping and Assembly with Qualities Viewer, M.A.Q Viewer 2026-02-14 02:00:56 0
Staden Package
 
Resource Report
Resource Website
50+ mentions
Staden Package (RRID:SCR_005629) software resource A fully developed set of DNA sequence assembly (Gap4 and Gap5), editing and analysis tools (Spin) for Unix, Linux, MacOSX and MS Windows. c, unix/linux, sequence assembly, dna/protein analysis, spin, sequence alignment, genome, genome viewer, c++, fortran, tcl, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:20513662
DOI:10.1093/bioinformatics/btq268
BSD License OMICS_00894, biotools:staden https://bio.tools/staden
https://sources.debian.org/src/staden/
SCR_005629 Staden Package 2026-02-14 02:01:09 79
metagen
 
Resource Report
Resource Website
10+ mentions
metagen (RRID:SCR_003443) metagen software resource Software program providing a method for meta-analysis of case-control genetic association studies using random-effects logistic regression. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:17605724 Free, Available for download, Freely available OMICS_00238, biotools:metagen https://www.rdocumentation.org/packages/meta/versions/4.9-6/topics/metagen SCR_003443 2026-02-14 02:00:27 18
eTRIKS
 
Resource Report
Resource Website
10+ mentions
eTRIKS (RRID:SCR_003765) eTRIKS portal, consortium, data or information resource, organization portal, service resource Research informatics and analytics platform for the IMI OncoTrack consortium. data sharing, drug discovery, translational research, informatics, knowledge management, metadata standard, platform, analytics, tool development, bio.tools uses: tranSMART
is used by: U-BIOPRED
is used by: Predict-TB
is used by: OncoTrack
is used by: ABIRISK
is used by: RA MAP
is listed by: Consortia-pedia
is listed by: Debian
is listed by: bio.tools
is related to: Roche
is related to: Janssen Research and Development
is related to: Merck
is related to: Pfizer Animal Genetics
is related to: Imperial College London; London; United Kingdom
is related to: French National Center for Scientific Research
is related to: Clinical Data Interchange Standards Consortium
is related to: University of Luxembourg; Luxembourg; Luxembourg
is related to: IDBS
is related to: BioSci Consulting
is related to: TraIT
is related to: EMIF
is related to: Open PHACTS
has parent organization: Imperial College London; London; United Kingdom
Innovative Medicines Initiative ;
EFPIA
PMID:29482119 biotools:eTRIKS, nlx_158034 https://bio.tools/eTRIKS SCR_003765 European Translational Information and Knowledge Management Services, European Translational Information & Knowledge Management Services 2026-02-14 02:00:31 10
RAREMETAL
 
Resource Report
Resource Website
10+ mentions
RAREMETAL (RRID:SCR_003573) RAREMETAL software resource A software program that facilitates the meta-analysis of rare variants from genotype arrays or sequencing. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Michigan; Ann Arbor; USA
PMID:24894501 biotools:raremetal, OMICS_00243 https://bio.tools/raremetal SCR_003573 2026-02-14 02:00:52 22
Enrichr
 
Resource Report
Resource Website
1000+ mentions
Enrichr (RRID:SCR_001575) Enrichr data analysis service, analysis service resource, production service resource, service resource, software application, software resource A web-based gene list enrichment analysis tool that provides various types of visualization summaries of collective functions of gene lists. It includes new gene-set libraries, an alternative approach to rank enriched terms, and various interactive visualization approaches to display enrichment results using the JavaScript library, Data Driven Documents (D3). The software can also be embedded into any tool that performs gene list analysis. System-wide profiling of genes and proteins in mammalian cells produce lists of differentially expressed genes / proteins that need to be further analyzed for their collective functions in order to extract new knowledge. Once unbiased lists of genes or proteins are generated from such experiments, these lists are used as input for computing enrichment with existing lists created from prior knowledge organized into gene-set libraries. bed, gene, software as a service, rna-seq, analyze, protein, function, gene list, visualization, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
PMID:23586463 Free, Freely available biotools:enrichr, SciRes_000171 https://bio.tools/enrichr SCR_001575 2026-02-14 02:00:06 4351
CisGenome
 
Resource Report
Resource Website
50+ mentions
CisGenome (RRID:SCR_001558) data analysis tool Integrated software tool for tiling array, ChIP-seq, genome and cis-regulatory element analysis. sequencing software, chip seq, downstream analysis, chip analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
works with: TileMap
PMID:18978777 Free, Available for download, Freely available OMICS_00423, biotools:cisgenome https://bio.tools/cisgenome http://biogibbs.stanford.edu/~jihk/CisGenome/index.htm SCR_001558 CisGenome v2.0 2026-02-14 02:00:06 82
vsn
 
Resource Report
Resource Website
1+ mentions
vsn (RRID:SCR_001459) vsn software resource Software package that implements a method for normalizing microarray intensities, both between colours within array, and between arrays. The method uses a robust variant of the maximum-likelihood estimator for the stochastic model of microarray data described in the references. The model incorporates data calibration (a.k.a. normalization), a model for the dependence of the variance on the mean intensity, and a variance stabilizing data transformation. Differences between transformed intensities are analogous to normalized log-ratios. However, in contrast to the latter, their variance is independent of the mean, and they are usually more sensitive and specific in detecting differential transcription. microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
Free, Available for download, Freely available OMICS_01977, biotools:vsn https://bio.tools/vsn SCR_001459 vsn - Variance stabilization and calibration for microarray data 2026-02-14 02:00:09 5
InterMine
 
Resource Report
Resource Website
10+ mentions
InterMine (RRID:SCR_001772) software resource An open source data warehouse system built for the integration and analysis of complex biological data that enables the creation of biological databases accessed by sophisticated web query tools. Parsers are provided for integrating data from many common biological data sources and formats, and there is a framework for adding data. InterMine includes a user-friendly web interface that works "out of the box" and can be easily customized for specific needs, as well as a powerful, scriptable web-service API to allow programmatic access to data. mac os x, unix/linux, windows, java, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Cambridge; Cambridge; United Kingdom
Wellcome Trust PMID:24753429 Free, Freely available OMICS_03840, biotools:intermine https://github.com/intermine/intermine
https://bio.tools/intermine
http://intermine.github.io/intermine.org/ SCR_001772 2026-02-14 02:00:07 22
An Integrated Multiple Structure Visualization and Multiple Sequence Alignment Application
 
Resource Report
Resource Website
An Integrated Multiple Structure Visualization and Multiple Sequence Alignment Application (RRID:SCR_001646) data visualization software, data processing software, data analysis software, software application, software resource, rendering software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Friend is a bioinformatics application designed for simultaneous analysis and visualization of multiple structures and sequences of proteins and/or DNA/RNA. The application provides basic functionalities such as: structure visualization with different rendering and coloring, sequence alignment, and simple phylogeny analysis, along with a number of extended features to perform more complex analyses of sequence structure relationships, including: structural alignment of proteins, investigation of specific interaction motifs, studies of protein-protein and protein-DNA interactions, and protein super-families. Friend is also useful for the functional annotation of proteins, protein modeling, and protein folding studies. Friend provides three levels of usage; 1) an extensive GUI for a scientist with no programming experience, 2) a command line interface for scripting for a scientist with some programming experience, and 3) the ability to extend Friend with user written libraries for an experienced programmer. The application is linked and communicates with local and remote sequence and structure databases. alignment, analysis, bioinformatics, database, dna, interaction, motif, phylogeny, protein, rna, scientist, sequence, structure, super-family, visualization, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Northeastern University; Massachusetts; USA
PMID:16076889 THIS RESOURCE IS NO LONGER IN SERVICE biotools:friend, nif-0000-10149 https://bio.tools/friend SCR_001646 FRIEND 2026-02-14 02:00:07 0
Prediction of Amyloid Structure Aggregation
 
Resource Report
Resource Website
100+ mentions
Prediction of Amyloid Structure Aggregation (RRID:SCR_001768) PASTA web application, data analysis service, analysis service resource, production service resource, service resource, software resource Online interface that utilizes an algorithm to predict the most aggregation-prone portions and the corresponding beta-strand inter-molecular pairing for a given input sequence. Users can paste the sequence into the interface and output the appropriate sequence. protein aggregation, sequence, dna, rna, amyloid structure, protein analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Padua; Padua; Italy
Padova University Progetto di Ateneo CPDA121890;
Italian Ministry for University and Research FIRB Futuro in Ricerca RBFR08ZSXY;
PMID:24848016 Free, Freely available biotools:pasta, OMICS_03861 https://bio.tools/pasta SCR_001768 PASTA 2.0, Prediction of amyloid structure aggregation 2026-02-14 02:00:07 177
unifiedWMWqPCR
 
Resource Report
Resource Website
unifiedWMWqPCR (RRID:SCR_001706) software resource Software package that implements the unified Wilcoxon-Mann-Whitney Test for qPCR data. This modified test allows for testing differential expression in qPCR data. standalone software, mac os x, unix/linux, windows, r, gene expression, microtitre plate assay, qpcr, differential expression, multiple comparison, quality control, visualization, qpcr, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24794933 Free, Available for download, Freely available OMICS_03937, biotools:unifiedwmwqpcr https://bio.tools/unifiedwmwqpcr SCR_001706 unifiedWMWqPCR - Unified Wilcoxon-Mann Whitney Test for testing differential expression in qPCR data 2026-02-14 02:00:16 0

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