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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GOnet
 
Resource Report
Resource Website
1+ mentions
GOnet (RRID:SCR_018977) software resource, data access protocol, web service, service resource, production service resource, analysis service resource Web tool for interactive Gene Ontology analysis of any biological data sources resulting in gene or protein lists. Gene Ontology, interactive analysis, data, gene, protein, gene list, protein list, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
works with: Gene Ontology
NIH Common Fund ;
NIGMS ;
NHGRI R24 HG010032;
NIAID U19 AI118610;
NIAID U19 AI118626
PMID:30526489 biotools:GOnet https://github.com/mikpom/gonet
https://bio.tools/GOnet
SCR_018977 2026-02-15 09:22:25 3
CAIRN
 
Resource Report
Resource Website
CAIRN (RRID:SCR_019101) software application, data visualization software, data processing software, software resource, data access protocol, web service Web tool to graph all copy number alterations present in segment file. Custom data is permitted. Allows to display copy number alterations which overlap user specified region, to quantify number of amplified CNAs and deleted CNAs. Visualization tool to explore copy number alterations discovered in published cancer datasets. Intended to help oncology community observe of relative rates of amplification, deletion, and mutation of interesting genes and regions. Deleted CNAs quantification, Copy Number Alterations, segment file, data visualization, published cancer datasets CNAs, amplified CNA quantification Nine Girls Ask Foundation ;
NCI CA207729;
NIGMS GM132055;
NCI CA107263;
NCI CA177519;
NCI CA102310;
NIA AG033082;
NCI P30 CA138313
PMID:31923184 Free, Available for download, Freely available https://github.com/jrdelaney/CAIRN SCR_019101 Copy Alterations Intuitive Rendering Navigator 2026-02-15 09:22:26 0
trRosetta
 
Resource Report
Resource Website
50+ mentions
trRosetta (RRID:SCR_021181) software application, simulation software, service resource, software resource Software tool for fast and accurate protein structure prediction. Builds protein structure based on direct energy minimizations with restrained Rosetta. Restraints include inter-residue distance and orientation distributions, predicted by deep residual neural network. Homologous templates are included in network prediction to improve accuracy for easy targets. protein structure, restraint-guided structure generation, protein structure prediction uses: Rosetta National Natural Science Foundation of China ;
Fok Ying-Tong Education Foundation ;
Key Laboratory for Medical Data Analysis and Statistical Research of Tianjin ;
Thousand Youth Talents Plan of China ;
China Scholarship Council ;
NIGMS R01 GM092802;
NIH Office of the Director DP5 OD026389
PMID:31896580 Free, Freely available https://github.com/gjoni/trRosetta SCR_021181 transformed restrained Rosetta 2026-02-15 09:21:58 67
HISAT2
 
Resource Report
Resource Website
10000+ mentions
HISAT2 (RRID:SCR_015530) software application, sequence analysis software, source code, data processing software, software resource, data analysis software Graph-based alignment of next generation sequencing reads to a population of genomes. alignment program, mapping reads, population genomics, human genome, bio.tools is used by: Fcirc
is listed by: Debian
is listed by: bio.tools
is related to: TopHat
has parent organization: Johns Hopkins University; Maryland; USA
is required by: SL-quant
is hosted by: GitHub
NLM R01-LM06845;
NIGMS R01-GM083873;
NSF CCF-0347992
PMID:25751142
DOI:10.1038/s41587-019-0201-4
Available for download OMICS_07225, biotools:hisat2 https://github.com/infphilo/hisat2
https://bio.tools/hisat2
https://sources.debian.org/src/hisat2/
SCR_015530 HISAT 2026-02-15 09:21:18 17595
GenePattern Notebook
 
Resource Report
Resource Website
1+ mentions
GenePattern Notebook (RRID:SCR_015699) systems interoperability software, software application, software resource, web application, electronic laboratory notebook Interactive analysis notebook environment that streamlines genomics research by interleaving text, multimedia, and executable code into unified, sharable, reproducible “research narratives.” It integrates the dynamic capabilities of notebook systems with an investigator-focused, simple interface that provides access to hundreds of genomic tools without the need to write code. gene, genomics research, research narrative, notebook system, analysis notebook, bio.tools is listed by: bio.tools
is listed by: Debian
is affiliated with: GenePattern
NIGMS R01-GM074024;
NCI U24-CA194107
PMID:28822753 Open Source, Free, Available for download, Account required biotools:GenePattern_notebook https://bio.tools/GenePattern_notebook SCR_015699 GenePattern Notebook environment 2026-02-15 09:21:36 3
UCSF ChimeraX
 
Resource Report
Resource Website
1000+ mentions
UCSF ChimeraX (RRID:SCR_015872) software application, data visualization software, data processing software, software resource, 3d visualization software, 4d visualization software Software for 3D/4D image reconstruction. UCSF ChimeraX is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. 3d, 4d, image reconstruction, molecular visualization, biocomputing, informatics, rbvi, ucsf, chimera is related to: UCSF Chimera
is related to: UCSF Chimera
has parent organization: University of California at San Francisco; California; USA
has plug in: ISOLDE
NIGMS P41 GM103311 SCR_015872 ChimeraX 2026-02-15 09:21:40 1825
exRNA Atlas
 
Resource Report
Resource Website
10+ mentions
exRNA Atlas (RRID:SCR_017221) organization portal, portal, expression atlas, data analysis service, software resource, database, ontology, data access protocol, atlas, service resource, storage service resource, consortium, production service resource, data repository, data or information resource, controlled vocabulary, analysis service resource, application programming interface Software tool as data and metadata repository of Extracellular RNA Communication Consortium. Atlas includes small RNA sequencing and qPCR derived exRNA profiles from human and mouse biofluids. All RNAseq datasets are processed using version 4 of exceRpt small RNAseq pipeline. Atlas accepts submissions for RNAseq or qPCR data. Differential, expression, RNA, sequencing, qPCR, data, visualization, extracellular, exRNA, atlas, repository, dataset is recommended by: National Library of Medicine
has parent organization: Baylor College of Medicine; Houston; Texas
has parent organization: exRNA
gastric cancer, colon carcinoma, colorectal cancer, prostate carcinoma, pancreatic carcinoma, multiple sclerosis, glioblastoma multiforme, ulcerative colitis, Alzheimer's disease, ischemic stroke, intraparenchymal hemorrhage of brain, asthma, cardiovascular disorder, myocardial infarction, lupus, nephrotic syndrome, transplanted kidney present, liver disease, transplanted liver present, pre-eclampsia, Parkinson disease, intraventricular brain hemorrhage, subarachnoid hemorrhage NIDA U54 DA036134;
NCI R01 CA163849;
NIGMS R25 GM056929;
NCATS UH3 TR000906;
NCI U19 CA179512;
NIDDK P30 DK63720;
NHLBI K23 HL127099;
NHLBI R01 HL136685;
NIA R01 AG059729;
NCATS UH3 TR000943;
NCI R35 CA209904;
NCI CA217685;
NHLBI R01 HL122547;
American Cancer Society ResearchProfessor Award ;
Frank McGraw Memorial Chair in CancerResearch
PMID:30951672 Restricted SCR_017221 2026-02-15 09:21:59 24
RNAstructure
 
Resource Report
Resource Website
10+ mentions
RNAstructure (RRID:SCR_017216) software application, software resource, data access protocol, web service, service resource, production service resource, simulation software, analysis service resource Web server for RNA and DNA secondary structure prediction and analysis. Software package as RNA folding prediction program. RNA, DNA, secondary, structure, prediction, analysis is listed by: SoftCite
has parent organization: University of Rochester; New York; USA
NIGMS R01 GM076485 PMID:23620284 Free, Freely available SCR_017216 2026-02-15 09:21:59 42
SerialEM
 
Resource Report
Resource Website
100+ mentions
SerialEM (RRID:SCR_017293) software application, data processing software, data acquisition software, software resource Software tool for automated EM data acquisition. Used for efficient tilt series acquisition and interface for image capture, display, and storage and for control of some aspects of microscope function. automated, data, acquisition, tilt, image, capture, display, storage, microscope NCRR RR00592;
NIGMS P01 GM61306
PMID:16182563 Restricted SCR_017293 2026-02-15 09:21:18 213
Protomo
 
Resource Report
Resource Website
1+ mentions
Protomo (RRID:SCR_017296) software application, image processing software, data processing software, software resource Software tool for electron tomography and 3D image processing. Software package used in electron tomography for marker free alignment and 3D reconstruction of tilt series. Tomography software package distributed for linux operating system and developed by Hanspeter Winkler. electron, tomography, 3D, image, processing NIGMS GM30598;
NIGMS GM64346
PMID:16973379 Restricted SCR_017296 2026-02-15 09:22:00 4
RaptorX
 
Resource Report
Resource Website
100+ mentions
RaptorX (RRID:SCR_018118) software application, software resource, data access protocol, web service, simulation software Software package and web server for protein structure and function prediction. Used for predicting 3D structures for protein sequences without close homologs in Protein Data Bank. Given input sequence, predicts its secondary and tertiary structures, contacts, solvent accessibility, disordered regions and binding sites. Assigns some confidence scores to indicate quality of predicted 3D model. Protein structure predictor, 3D structure, protein sequence, secondary and tertiary structure, binding site, solvent accessibility, disordered region, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Chicago; Illinois; USA
NIGMS R01 GM089753;
NSF DBI 0960390
PMID:21987485 Restricted biotools:raptorx https://bio.tools/raptorx SCR_018118 2026-02-15 09:22:10 149
UltraScan
 
Resource Report
Resource Website
10+ mentions
UltraScan (RRID:SCR_018126) software application, data processing software, data analysis software, software resource Software package for hydrodynamic data from analytical ultracentrifugation experiments. Features integrated data editing and analysis environment with portable graphical user interface. Provides resolution for sedimentation velocity experiments using high-performance computing modules for 2-dimensional spectrum analysis, genetic algorithm, and for Monte Carlo analysis. Hydrodynamic data, analytical ultracentrifugation experiment, data editing, analysis, sedimentation velocity experiment, spectrum analysis, genetic algorithm, Monte Carlo analysis NSF DBI 9724273;
NSF DBI 9974819;
NSF ANI 228927;
NSF TG-MCB 060019T;
NSF TG-MCB 070038;
NSF TG-MCB 070039;
NSF TG-MCB 070040;
NSF OCI 1032742;
NSF ACI 1339649;
NCRR RR022200;
NCRR RR 022200 03S1;
NIGMS GM120600;
San Antonio Life Science Institute ;
Howard Hughes Medical Institute ;
Robert J. Kleberg Jr. and Helen C. Kleberg Foundation
Free, Available for download, Freely available SCR_018126 2026-02-15 09:21:32 20
Track-A-Worm
 
Resource Report
Resource Website
1+ mentions
Track-A-Worm (RRID:SCR_018299) software application, data processing software, data analysis software, software resource Open source system for quantitative assessment of C. Elegans locomotory and bending behavior. Used for quantitative behavioral analyses to understand circuit and gene bases of behavior. Constantly records and analyzes position and body shape of freely moving worm at high magnification. Quantitative assessment, C.Elegans locomotory, bending behavior, behavioral analysis, gene, moving worm position, body shape, automated recording is related to: University of Connecticut; Connecticut; USA NIGMS R01 GM083049;
NIMH R01 MH085927
PMID:23922769 Free, Available for download, Freely available SCR_018299 Tracker-A-Worm version 1.0, Tracker-A-Worm version 2.0 2026-02-15 09:22:12 3
Motif Mutation Analysis for Regulatory Genomic Elements
 
Resource Report
Resource Website
500+ mentions
Motif Mutation Analysis for Regulatory Genomic Elements (RRID:SCR_021902) MMARGE software application, data processing software, software resource, software toolkit, data analysis software Software package that integrates genome wide genetic variation with epigenetic data to identify collaborative transcription factor pairs. Optimized to work with chromatin accessibility assays such as ATAC-seq or DNase I hypersensitivity, as well as transcription factor binding data collected by ChIP-seq. Used to identify combinations of cell type specific transcription factors while simultaneously interpreting functional effects of non-coding genetic variation. genome wide genetic variation, epigenetic data, identify collaborative transcription factor pairs, interpreting functional effects, non-coding genetic variation NCI CA173903;
NIGMS GM085764;
NIDDK DK091183;
NHLBI R00 123485
PMID:29893919 Free, Available for download, Freely available SCR_021902 2026-02-15 09:22:44 608
3DRefine
 
Resource Report
Resource Website
10+ mentions
3DRefine (RRID:SCR_021883) web service, data access protocol, software resource Interactive web server for efficient protein structure refinement with capability to perform web based statistical and visual analysis. efficient protein structure refinement, statistical and visual analysis NIGMS R01 GM093123 DOI:10.1093/nar/gkw336 Free, Freely available SCR_021883 2026-02-15 09:22:42 20
OpenSim
 
Resource Report
Resource Website
500+ mentions
OpenSim (RRID:SCR_002683) software application, simulation software, software resource OpenSim is an open-source software system that lets users develop models of musculoskeletal structures and create dynamic simulations of movement. The software provides a platform on which the biomechanics community can build a library of simulations that can be exchanged, tested, analyzed, and improved through multi-institutional collaboration. The underlying software is written in ANSI C++, and the graphical user interface (GUI) is written in Java. OpenSim technology makes it possible to develop customized controllers, analyses, contact models, and muscle models among other things. These plugins can be shared without the need to alter or compile source code. Users can analyze existing models and simulations and develop new models and simulations from within the GUI. muscle-driven simulation, musculoskeletal biomechanics, neuromuscular simulation, modeling software, simulation software is related to: Simtk.org
is related to: Neuromuscular Models Library
has parent organization: Stanford University; Stanford; California
Simbios ;
NIGMS U54 GM072970;
DARPA
Public, Free, Acknowledgement requested nif-0000-23308 https://simtk.org/home/opensim
http://opensim.stanford.edu/support/index.html
SCR_002683 2026-02-15 09:18:21 546
Seg3D
 
Resource Report
Resource Website
100+ mentions
Seg3D (RRID:SCR_002552) Seg3D software application, data visualization software, image processing software, data processing software, software resource, segmentation software, rendering software, image analysis software A free volume processing segmenting tool that combines a flexible manual interface with powerful image processing and segmentation algorithms. Users can explore and label image volumes using slice windows and 3D volume rendering. analyze, c++, dicom, image display, linux, macos, microsoft, magnetic resonance, nrrd, posix/unix-like, rendering, segmentation, three dimensional display, visualization, volume rendering, win32 (ms windows), windows is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Utah; Utah; USA
NIGMS 8 P41 GM103545-15 PMID:29083867 Free, Available for download, Freely available nlx_155959 http://www.nitrc.org/projects/seg3d SCR_002552 2026-02-15 09:18:20 101
SOURCE
 
Resource Report
Resource Website
50+ mentions
SOURCE (RRID:SCR_005799) SOURCE data analysis service, database, service resource, production service resource, data or information resource, analysis service resource SOURCE compiles information from several publicly accessible databases, including UniGene, dbEST, UniProt Knowledgebase, GeneMap99, RHdb, GeneCards and LocusLink. GO terms associated with LocusLink entries appear in SOURCE. The mission of SOURCE is to provide a unique scientific resource that pools publicly available data commonly sought after for any clone, GenBank accession number, or gene. SOURCE is specifically designed to facilitate the analysis of large sets of data that biologists can now produce using genome-scale experimental approaches Platform: Online tool genomic, functional annotation, ontology, gene expression, gene, genome, statistical analysis, bio.tools, FASEB list is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: SMD
NIGMS ;
NCI CA85129-04;
NIGMS GM07365
PMID:12519986 Restricted biotools:source, nlx_149287 https://login.stanford.edu/idp/profile/SAML2/Redirect/SSO?execution=e1s1
https://bio.tools/source
SCR_005799 2026-02-15 09:19:04 69
SBO
 
Resource Report
Resource Website
1+ mentions
SBO (RRID:SCR_006753) SBO database, data or information resource, ontology, controlled vocabulary A set of controlled, relational vocabularies of terms commonly used in Systems Biology, and in particular in computational modeling. The ontology consists of seven orthogonal vocabularies defining: the roles of reaction participants (eg. substrate), quantitative parameters (eg. Michaelis constant), a precise classification of mathematical expressions that describe the system (eg. mass action rate law), the modeling framework used (eg. logical framework), and a branch each to describe entity (eg. macromolecule) and interaction (eg. process) types, and a branch to define the different types of metadata that may be present within a model. SBO terms can be used to introduce a layer of semantic information into the standard description of a model, or to annotate the results of biochemical experiments in order to facilitate their efficient reuse. SBO is an Open Biomedical Ontologies (OBO) candidate ontology, and is free for use. A programmatic access to the content of the Systems Biology Ontology is provided by Web Services. systems biology, computational modeling, web service, obo, gold standard is listed by: BioPortal
is related to: BioModels.net
is related to: OBO
has parent organization: European Bioinformatics Institute
NIGMS PMID:17118155 Free, The community can contribute to this resource nlx_66206 SCR_006753 Systems Biology Ontology 2026-02-15 09:19:19 4
iBioSeminars
 
Resource Report
Resource Website
iBioSeminars (RRID:SCR_005848) iBioSeminars training material, data or information resource, narrative resource, video resource iBioSeminars offers: * Free, on-demand lectures: Many universities/colleges have limited access to high profile leaders in biological research. Our goal is to add 15-20 seminars per year, of similar quality to outstanding lectures that are currently in this library. Access, through web streaming or download, is completely free-of-charge. * Targeting a broad audience: iBioSeminars start with an extended introduction, making them accessible to non-specialists and students, and then progress to cover current research. Senior scientists and students can view and enjoy these lectures. * Education: iBioSeminars are being used by undergraduate and graduate teachers to augment their classroom material. We have now added an education component to this web site (including lecture notes, questions/answers and short video clips for teaching). * International communication: iBioSeminars have viewers in 115 countries and they are being internally promoted in several countries as an educational tool and scientific resource. * Goodwill: Lecturers generously donate their time to prepare these lectures. The project, largely funded by HHMI, is a grass roots efforts with time invested by several individuals at UCSF, HHMI and ASCB. biological research, biology, lecture, seminar, education, undergraduate, graduate has parent organization: University of California at San Francisco; California; USA
has parent organization: American Society for Cell Biology
has parent organization: Howard Hughes Medical Institute
NSF ;
NIGMS ;
Howard Hughes Medical Institute
Licensed under a Creative Commons Attribution-NonCommercial-NoDerivs v3 Unported License. nlx_149380 SCR_005848 iBioSeminars - Bringing the World''s Best Biology to You, iBioSeminars - Bringing the Worlds Best Biology to You, iBioSeminars.org 2026-02-15 09:19:05 0

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