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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MMPC-Vanderbilt University School of Medicine Cardiovascular Pathophysiology Core
 
Resource Report
Resource Website
MMPC-Vanderbilt University School of Medicine Cardiovascular Pathophysiology Core (RRID:SCR_015353) access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 6th,2023. Core whose objective is to provide investigators at Vanderbilt and outside institutions a means to accurately assess cardiovascular phenotypes in mouse models of diabetes and metabolic disease. The CPC uses validated approaches and state-of-the-art instrumentation that allow for sensitive screening of phenotypic variations. cardiovascular phenotype, cardiovascular mouse model, diabetes mouse model, metabolic mouse model is listed by: NIDDK Information Network (dkNET)
has parent organization: National Mouse Metabolic Phenotyping Centers
has parent organization: MMPC-Vanderbilt University School of Medicine
is organization facet of: MMPC-Vanderbilt University School of Medicine
Diabetes, metabolic disease NIDDK U24 DK059637 THIS RESOURCE IS NO LONGER IN SERVICE SCR_015353 2026-02-15 09:20:52 0
MMPC-University of California Davis Energy Balance Exercise and Behavior Core
 
Resource Report
Resource Website
1+ mentions
MMPC-University of California Davis Energy Balance Exercise and Behavior Core (RRID:SCR_015364) access service resource, core facility, service resource, resource Core that provides investigators with services to accurately measure the major components of energy balance in their mouse models and tests that allow investigators to examine physiological factors that may influence food intake or energy expenditure. energy balance, exercise and behavior, obesity is listed by: NIDDK Information Network (dkNET)
has parent organization: University of California at Davis; California; USA
has parent organization: National Mouse Metabolic Phenotyping Centers
has parent organization: MMPC-University of California Davis
is organization facet of: MMPC-University of California Davis
Obesity, Diabetes, metabolic disease NIDDK DK092993 Available to the research community SCR_015364 2026-02-15 09:21:14 6
Rhesus Monkey Breeding and Research
 
Resource Report
Resource Website
Rhesus Monkey Breeding and Research (RRID:SCR_008357) RMBRR material resource, tissue bank, biomaterial supply resource This colony provides a national resource of rhesus monkeys and their tissues to carry out research benefiting the scientific community. The RMBRR maintains a colony of monkeys that have been derived to be specific pathogen free for members of both the herpes and retrovirus families. Over its history, the RMBRR has developed specialized management techniques, housing facilities and highly trained staff to avail these purposefully bred laboratory models, which are 93% genetically identical to humans, to researchers worldwide. Historically, this animal model has been instrumental in research involving blood classification, polio vaccine development, and drug safety and efficacy while currently they are the preferred model for studying the mechanisms of immunodeficiency diseases. Their susceptibility to Simian Immunodeficiency Virus and their homology to the human major histocompatibility complex (MHC) Class I, II and TCR genes make them valuable in HIV research. They are currently the models of choice for HIV/AIDS vaccine development and study. Other areas of research include atherosclerosis, myocarditis, alcoholism, diabetes, cancer and aging. The overall objectives of this resource are to improve the resources available at the RMBRR and to conduct resource-relevant research that improves both the health of the rhesus colony and its usefulness for studies of human disease. The Resource and Management Core is responsible for providing animal resources, tissues/biological fluids, cell lines, expert advice and research support to NIH extramural and intramural programs, other federal agencies and to private sponsors. The Resource-Related Research Core conducts research to improve the health of the animals maintained with special emphasis on studies that will enhance the usefulness of the rhesus as a model for studies of human disease. animal model, tissue, live animal, cell line, bodily fluid, vaccine development, vaccine is listed by: One Mind Biospecimen Bank Listing
has parent organization: University of Texas MD Anderson Cancer Center
Immunodeficiency disease, Human immunodeficiency virus, AIDS, Atherosclerosis, Myocarditis, Alcoholism, Diabetes, Cancer, Aging Public: available to researchers worldwide nif-0000-25893 SCR_008357 KCCMR Rhesus Monkey Breeding and Research, KCCMR RMBRR, Keeling Center for Comparative Medicine and Research Rhesus Monkey Breeding and Research 2026-02-15 09:19:48 0
Pancreatlas
 
Resource Report
Resource Website
10+ mentions
Pancreatlas (RRID:SCR_018567) atlas, data or information resource Collection of human pancreas data and images. Platform to share data from human pancreas samples. Houses reference datasets from human pancreas samples, achieved through generosity of organ donors and their families. Human pancreas data, pancreas image, reference dataset, human pancreas sample, organ donor pancreas data lists: Exeter Archival Diabetes Biobank (EADB)
is related to: Vanderbilt University; Tennessee; USA
is related to: Human Islet Research Network (HIRN)
works with: Exeter Archival Diabetes Biobank (EADB)
Type 1 diabetes, Diabetes, Type 2 diabetes, Cystic Fibrosis-Related Diabetes Leona M. and Harry B. Helmsley Charitable Trust ;
NIDDK DK104211;
NIDDK DK108120;
NIDDK DK112232;
NIDDK DK106755;
NIDDK DK20593;
NCI CA68485;
NIDDK DK58404;
NIDDK DK59637;
NEI EY08126
Free, Freely available SCR_018567 2026-02-15 09:22:16 10
Tabula Sapiens
 
Resource Report
Resource Website
10+ mentions
Tabula Sapiens (RRID:SCR_022314) atlas, data or information resource Single cell transcriptomic atlas of multiple organs from individual human donors. Multiple organ, single cell transcriptomic atlas of humans. Molecular reference atlas for cell types of human body. Provides molecular definition of these cell types and reveals many other aspects of human biology, including how same gene can be spliced differently in different cell types, how shared cell types in different tissues can have subtle differences in their identities, and how clones of immune system can be shared across tissues. Single cell transcriptomic atlas, multiple organs, human donors, molecular reference atlas diabetes, cancer, hypertension, coronary artery disease, hyperlipidemia, bipolar, depression, deep vein thrombosis, flu, mitral regurgitation, osteopenia, venous thromboembolic disease, lupus, pulmonary hypertension, schizophrehnia, seizure, asthma, atrial fibrillation, asplenia, ezcema, hypercholesterolemia, chronic lung disease Chan Zuckerberg Initiative DOI:10.1101/2021.07.19.452956 Free, Freely available SCR_022314 2026-02-15 09:22:48 32
Genetics of Kidneys in Diabetes
 
Resource Report
Resource Website
Genetics of Kidneys in Diabetes (RRID:SCR_000133) GoKinD, Go KinD material resource, biomaterial supply resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Collect, store, and distribute genetic samples from cases and controls of type 1 diabetes and diabetic nephropathy for investigator-driven research into the genetic basis of diabetic nephropathy. As the risk of kidney complications in type 1 diabetes appears to have a considerable genetic component, this study assembled a large data resource for researchers attempting to identify causative genetic variants. The types of data collected allowed traditional case-control testing, a rapid and often powerful approach, and family-based analysis, a robust approach that is not influenced by population substructure. clinical, genetics, genetic variant, gene, data set is listed by: One Mind Biospecimen Bank Listing
is listed by: NIDDK Information Network (dkNET)
has parent organization: George Washington University; Washington D.C.; USA
Type 1 diabetes, Diabetes, Diabetic nephropathy, Kidney disease JDRF ;
NIH
PMID:16775037 THIS RESOURCE IS NO LONGER IN SERVICE nlx_152764 http://www.gokind.org/access SCR_000133 Genetics of Kidneys in Diabetes (GoKinD) Study, Genetics of Kidneys in Diabetes Study 2026-02-15 09:17:52 0
Living Biobank
 
Resource Report
Resource Website
Living Biobank (RRID:SCR_001510) Living Biobank material resource, biomaterial supply resource Provides investigators with the opportunity to obtain on-demand biological samples from selected individuals that TrialNet has developed through the longitudinal monitoring of individuals at risk for the development of type 1 diabetes within the Natural History study. Exploratory research is encouraged under this initiative. Studies must use TrialNet screened subjects, and cannot interfere with ongoing clinical trials or studies. Investigators can select the clinical characteristics needed for their study as well as the sample type and collection frequency. Although many Living Biobank studies may be implemented through cost-sharing with the TrialNet network, special sample collections and visits outside of the normal visit schedules will incur additional costs which should be covered by the approved applicant. In addition, some studies may require effort from the TrialNet coordinating center, with costs covered by the approved ancillary study. Living biobank studies will be evaluated with careful consideration for their potential impact on the objectives and performance of the TrialNet Natural History study. To protect the interests of TrialNet, each living biobank study must be reviewed and approved by the Ancillary Studies Committee before its initiation. All approved living biobank studies will be reviewed yearly to evaluate their progress, and impact on TrialNet as a whole. TrialNet welcomes the submission of living biobank studies as an adjunct to ongoing protocols. whole blood, serum, plasma, dna, rna, peripheral blood mononuclear cell, blood is listed by: One Mind Biospecimen Bank Listing
has parent organization: Type 1 Diabetes TrialNet
Type 1 diaberes, Diabetes Free, Freely available nlx_152813 SCR_001510 TrialNet Living Biobank 2026-02-15 09:18:07 0
Boston Area Diabetes Endocrinology Research Center Metabolic Physiology and Energy Balance Core Facility
 
Resource Report
Resource Website
Boston Area Diabetes Endocrinology Research Center Metabolic Physiology and Energy Balance Core Facility (RRID:SCR_008293) access service resource, core facility, service resource Core in BADERC that provides services in consultation and teaching, use of DEXA scanner for determination of body fat and/or bone density, and use of Coulter Counter to measure cell number and cell size distribution. animal physiology, metabolic physiology is listed by: Eagle I
is listed by: NIDDK Information Network (dkNET)
has parent organization: Harvard University; Cambridge; United States
is organization facet of: Boston Area Diabetes Endocrinology Research Center
Diabetes NIDDK P30 DK057521 Available to the research community, Fee for service nlx_156297 http://www.baderc.org/cores/metabolicCore.html http://www.baderc.org/cores/metabolicCore.html SCR_008293 Boston Area Diabetes Endocrinology Research Center Metabolic Physiology 2026-02-15 09:19:46 0
HMS Human Sample Procurement Core Facility
 
Resource Report
Resource Website
HMS Human Sample Procurement Core Facility (RRID:SCR_009797) access service resource, core facility, service resource Core facility that provides the following services: Autoantibody determination, HLA typing and Genotyping for the best recognized susceptibility loci (INS, PTPN22, CTLA4).

The Human Sample Procurement Core will support translational research endeavors within the JDRF Center by providing the Center''s laboratories access to well-characterized blood samples from patients with diabetes at different stages of the disease. This availability will greatly facilitate the translational exploration of concepts and targets emerging from the basic research projects. Individuals with T1D (recent onset, long-standing Type-1 diabetes) and matched controls (healthy or T2D) will be recruited from the patient population at the Joslin Diabetes Center and neighboring institutions. The Core will perform and record a basic characterization of patients and their samples. This analysis will include a thorough evaluation of clinical characteristics from a diabetes and autoimmune standpoint, and an immunogenetic workup (outsourced to Joslin or other cores): autoantibody determination, HLA typing and genotyping for the best recognized susceptibility loci (INS, PTPN22, CTLA4). A relational database will be adapted to record all patient information, copies of which will be provided in a de-identified manner to the investigators.
immunoassay, genotyping assay is listed by: Eagle I
has parent organization: Harvard Medical School; Massachusetts; USA
Type 1 diabetes, Type 2 diabetes, Diabetes nlx_156265 http://citdh.org/mock_new2_content.html SCR_009797 2026-02-15 09:20:15 0
HMS Genetically Modified NOD Mouse Core Facility
 
Resource Report
Resource Website
1+ mentions
HMS Genetically Modified NOD Mouse Core Facility (RRID:SCR_009796) access service resource, core facility, service resource Core facility that provides the following services: Maintainence and dissemination of transgenic and mutant mice.

The Genetically Modified NOD Mouse Core provides Center investigators, as well as researchers elsewhere, with access to transgenic and mutant lines derived from the NOD mouse model: some will be generated within the Core; others are established lines of proven experimental value that are maintained in the Core. The Core will construct transgenic mice in strains that have a high susceptibility to diabetes (in particular in the NOD line). This includes trangenesis by conventional pronuclear injection or by delivery of RNAi cassettes on lentiviral vectors. The Core will also provide a panel of existing transgenic and mutant lines. These lines are chosen because of their established interest in allowing the dissection of immunological tolerance in Type 1 Diabetes, and in response to Center investigator needs.
laboratory animal care is listed by: Eagle I
has parent organization: Harvard Medical School; Massachusetts; USA
Type 1 Diabetes, Diabetes nlx_156264 http://cbdm.hms.harvard.edu/Transgenics/mice_available.html
http://immdiv.hms.harvard.edu
SCR_009796 2026-02-15 09:19:49 1
Joslin Diabetes Center Flow Cytometry Core Facility
 
Resource Report
Resource Website
500+ mentions
Joslin Diabetes Center Flow Cytometry Core Facility (RRID:SCR_009878) access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides cell sorting and flow cytometry services. Specific services include cell analysis, large object sorting,magnetic cell enrichment, and automatic cell counting. flow cytometry, flow cytometry service, cell sorting, cell analysis is listed by: Eagle I
is listed by: NIDDK Information Network (dkNET)
has parent organization: Joslin Diabetes Center
is organization facet of: Joslin Diabetes Center
Diabetes NIDDK P30DK036836 THIS RESOURCE IS NO LONGER IN SERVICE nlx_156348 SCR_009878 2026-02-15 09:20:16 590
Joslin Diabetes Center Animal Physiology Core Facility
 
Resource Report
Resource Website
500+ mentions
Joslin Diabetes Center Animal Physiology Core Facility (RRID:SCR_009876) access service resource, core facility, service resource, resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides technically advanced physiological evaluation of metabolism in diabetes, obesity, and their associated complications in rodents for DRC investigators and outside users. It also provides training of investigators and trainees in several physiological procedures. physiological evaluation, diabetes metabolism, obesity metabolism, rodent research, diabetes rodent research, physiological procedure training is listed by: Eagle I
is listed by: NIDDK Information Network (dkNET)
has parent organization: Joslin Diabetes Center
is organization facet of: Joslin Diabetes Center
Diabetes NIDDK P30DK036836 THIS RESOURCE IS NO LONGER IN SERVICE nlx_156346 SCR_009876 2026-02-15 09:20:09 590
Joslin Diabetes Center Advanced Microscopy Core Facility
 
Resource Report
Resource Website
500+ mentions
Joslin Diabetes Center Advanced Microscopy Core Facility (RRID:SCR_009875) access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides services for performing specific morphological procedures, providing training and access to equipment, maintaining the specialized microscopes, and giving advice and interpretation. morphology service, training service, microscope maintanence, is listed by: Eagle I
is listed by: NIDDK Information Network (dkNET)
has parent organization: Joslin Diabetes Center
is organization facet of: Joslin Diabetes Center
Diabetes NIDDK P30DK036836 THIS RESOURCE IS NO LONGER IN SERVICE nlx_156345 SCR_009875 2026-02-15 09:20:13 590
Joslin Diabetes Center Advanced Genomics and Genetics Core Facility
 
Resource Report
Resource Website
500+ mentions
Joslin Diabetes Center Advanced Genomics and Genetics Core Facility (RRID:SCR_009873) access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27,2023. Core that provides services for genetic and genomic analysis, including DNA extraction from blood, access to DNA collections from the Core?s repository, SNP genotyping, and support for gene expression studies based on both high-density oligonucleotide arrays and real-time quantitative PCR. gene analysis, genome analysis, dna extraction, gene expression service is listed by: Eagle I
is listed by: NIDDK Information Network (dkNET)
has parent organization: Joslin Diabetes Center
is organization facet of: Joslin Diabetes Center
Diabetes NIDDK P30DK036836 THIS RESOURCE IS NO LONGER IN SERVICE nlx_156350 SCR_009873 2026-02-15 09:20:16 590
Jackson Heart Study
 
Resource Report
Resource Website
50+ mentions
Jackson Heart Study (RRID:SCR_009902) access service resource, core facility, service resource The JHS is the largest single-site longitudinal, population-based, cohort study of 5,302 persons initiated in the fall of 2000 to prospectively investigate the determinants of CVD among African Americans in the Jackson, MS metropolitan statistical area. The JHS investigates the various genotype and phenotype factors that affect high blood pressure, heart disease, strokes, diabetes and other important diseases in African Americans. The primary objective of the Jackson Heart Study is to investigate the causes of cardiovascular disease (CVD) in African Americans to learn how to best prevent this group of diseases in the future. More specific objectives include: 1. Identification of factors, which influence the development, and worsening of CVD in African Americans, with an emphasis on manifestations related to high blood pressure (such as remodeling of the left ventricle of the heart, coronary artery disease, heart failure, stroke and disorders affecting the blood vessels of the kidney). 2. Building research capabilities in minority institutions at the undergraduate and graduate level by developing partnerships between minority and majority institutions and enhancing participation of minority investigators in large-scale epidemiologic studies. 3. Attracting minority students to and preparing them for careers in health sciences. is listed by: Eagle I
is related to: A Whole Genome Admixture Scan for Type 2 Diabetes in African Americans
has parent organization: Jackson State University; Mississippi; USA
Diabetes, Cardiovascular disease, Kidney disease, Respiratory disease nlx_156367 SCR_009902 2026-02-15 09:20:13 71
Penn Diabetes Research Center Radioimmunoassay and Biomarkers Core Facility
 
Resource Report
Resource Website
Penn Diabetes Research Center Radioimmunoassay and Biomarkers Core Facility (RRID:SCR_010028) access service resource, core facility, service resource Core which offers high quality immunoassay services to basic, translational, and clinical investigators performing diabetes and related metabolic disease research. The core also provides consultation and training and education services. assay service, diabetes research, immunoassay consultation is listed by: Eagle I
is listed by: NIDDK Information Network (dkNET)
has parent organization: University of Pennsylvania; Philadelphia; USA
has parent organization: Penn Diabetes Research Center
is organization facet of: Penn Diabetes Research Center
Diabetes NIDDK P30DK19525 Restricted nlx_156498 SCR_010028 Penn Diabetes Research Center Radioimmunoassay and Biomarkers Core 2026-02-15 09:19:54 0
Vanderbilt Diabetes Research and Training Center Hormone Assay and Analytical Services Core Facility
 
Resource Report
Resource Website
Vanderbilt Diabetes Research and Training Center Hormone Assay and Analytical Services Core Facility (RRID:SCR_010181) access service resource, core facility, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility that supports diabetes, endocrine, and metabolic research across a range of species. Its objective is to provide sensitive, reproducible, and inexpensive analyses of hormones, amino acids, and other relevant chemicals. diabetes, endocrine, hormone, metabolic, chemical analysis is listed by: Eagle I
is listed by: NIDDK Information Network (dkNET)
has parent organization: Vanderbilt University; Tennessee; USA
has parent organization: Vanderbilt Diabetes Research and Training Center
is organization facet of: Vanderbilt Diabetes Research and Training Center
Diabetes NIDDK DK059637;
NIDDK DK020593
THIS RESOURCE IS NO LONGER IN SERVICE nlx_156660 SCR_010181 , Vanderbilt Hormone Assay & Analytical Services Core, Vanderbilt Diabetes Research and Training Center Hormone Assay and Analytical Services Core 2026-02-15 09:20:20 0
Vanderbilt Diabetes Research and Training Center Cell Imaging Shared Resource Core Facility
 
Resource Report
Resource Website
Vanderbilt Diabetes Research and Training Center Cell Imaging Shared Resource Core Facility (RRID:SCR_010165) access service resource, core facility, service resource, resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility that provides any Vanderbilt researcher with access to imaging equipment and expert technical support for microscopy and analysis of tissue and cellular physiology. diabetes, imaging equipment, microscopy, tissue analysis, cellular physiology is listed by: Eagle I
is listed by: NIDDK Information Network (dkNET)
has parent organization: Vanderbilt University; Tennessee; USA
has parent organization: Vanderbilt Diabetes Research and Training Center
is organization facet of: Vanderbilt Diabetes Research and Training Center
Diabetes NIDDK DK020593 THIS RESOURCE IS NO LONGER IN SERVICE nlx_156644 SCR_010165 Vanderbilt Diabetes Research and Training Center Cell Imaging Shared Resource 2026-02-15 09:19:57 0
Islet Cell Resource Centers
 
Resource Report
Resource Website
100+ mentions
Islet Cell Resource Centers (RRID:SCR_002806) ICR material resource, cell repository, biomaterial supply resource Group of 10 academic laboratories provide pancreatic islets of cGMP-quality to eligible investigators for use in FDA approved, IRB-approved transplantation protocols in which isolated human islets are transplanted into qualified patients afflicted with type 1 diabetes mellitus; optimize the harvest, purification, function, storage, and shipment of islets while developing tests that characterize the quality and predict the effectiveness of islets transplanted into patients with diabetes mellitus; and provide pancreatic islets for basic science studies. The centers are electronically linked through an Administrative and Bioinformatics Coordinating Center (ABCC). The ABCC manages a system with objectively defined criteria that establishes the order of priority for islet distribution. It also provides database and other informatics to track the utilization of pancreata and all distributed clinical grade islets for transplant and basic research, and supports the Islet Cell Resource Centers Consortium so that the research community has a single entry point to the program. Qualified researchers from domestic institutions may request islets by submitting a written application to the director of the ABCC. The ICRs will distribute Islets as appropriate for either clinical or basic science protocol use to eligible investigators who have received a favorable review and subsequent approval by the ICR Steering Committee (SC). The Administrative and Bioinformatics Coordinating Center (ABCC) manages the distribution according to a priority list. The ABCC will give preference to investigators who have peer-reviewed, NIH-funded research support. pancreatic islet, clinical is listed by: One Mind Biospecimen Bank Listing
is related to: One Mind Biospecimen Bank Listing
is related to: NIDDK Information Network (dkNET)
Type 1 diabetes, Diabetes NIDDK ;
Juvenile Diabetes Research Foundation International ;
NCRR 1 U42 RR17673
Free, Freely available, Available for download nif-0000-25418 SCR_002806 2026-02-15 09:18:24 123
Beta Cell Biology Consortium
 
Resource Report
Resource Website
50+ mentions
Beta Cell Biology Consortium (RRID:SCR_005136) BCBC material resource, cell repository, biomaterial supply resource THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented on August 1, 2015. Consortium that aims to facilitate interdisciplinary collaborations to advance the understanding of pancreatic islet development and function, with the goal of developing innovative therapies to correct the loss of beta cell mass in diabetes, including cell reprogramming, regeneration and replacement. They are responsible for collaboratively generating the necessary reagents, mouse strains, antibodies, assays, protocols, technologies and validation assays that are beyond the scope of any single research effort. The scientific goals for the BCBC are to: * Use cues from pancreatic development to directly differentiate pancreatic beta cells and islets from stem / progenitor cells for use in cell-replacement therapies for diabetes, * Determine how to stimulate beta cell regeneration in the adult pancreas as a basis for improving beta cell mass in diabetic patients, * Determine how to reprogram progenitor / adult cells into pancreatic beta-cells both in-vitro and in-vivo as a mean for developing cell-replacement therapies for diabetes, and * Investigate the progression of human type-1 diabetes using patient-derived cells and tissues transplanted in humanized mouse models. Many of the BCBC investigator-initiated projects involve reagent-generating activities that will benefit the larger scientific community. The combination of programs and activities should accelerate the pace of major new discoveries and progress within the field of beta cell biology. RIN, Resource Information Network, pancreatic islet, mouse, beta cell, pancreas, pancreatic development, embryonic stem cell, cell line, genomics, antibody, adenovirus, functional genomics, mouse embryonic stem cell line, mouse strain, protocol, embryonic stem cell line, data sharing, data set, gene expression, gene, pancreatic islet development, pancreatic islet function, basic science, basic research, cell reprogramming, cell regeneration, cell replacement, RRID Community Authority is used by: NIF Data Federation
is used by: Integrated Animals
is used by: NIDDK Information Network (dkNET)
is listed by: One Mind Biospecimen Bank Listing
is listed by: re3data.org
is listed by: Consortia-pedia
is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
is listed by: Resource Information Network
is related to: dkCOIN
is related to: Karolinska Institute; Stockholm; Sweden
is related to: University of California at Los Angeles; California; USA
is related to: Stanford University; Stanford; California
is related to: University of Massachusetts Medical School; Massachusetts; USA
is related to: Hebrew University Hadassah Medical School; Jerusalem; Israel
is related to: Philipps-University Marburg; Marburg; Germany
is related to: Imperial College London; London; United Kingdom
is related to: Childrens Hospital of Philadelphia - Research Institute; Pennsylvania; USA
is related to: Icahn School of Medicine at Mount Sinai; New York; USA
is related to: University of California at San Francisco; California; USA
is related to: Massachusetts Institute of Technology; Massachusetts; USA;
is related to: Hadassah Medical Center; Jerusalem; Israel
is related to: DanStem
is related to: Oregon Health and Science University; Oregon; USA
is related to: Vanderbilt University; Tennessee; USA
is related to: University of Chicago; Illinois; USA
is related to: University of Massachusetts; Massachusetts; USA
is related to: University of Colorado Boulder; Colorado; USA
is related to: Vrije Universiteit Brussel; Brussels; Belgium
is related to: University of Geneva; Geneva; Switzerland
is related to: University of Pennsylvania Perelman School of Medicine; Pennsylvania; USA
is related to: McEwen Centre for Regenerative Medicine
is related to: Seattle Childrens Research Institute; Washington; USA
is related to: Columbia University; New York; USA
is related to: University of Texas Southwestern Medical Center; Texas; USA
is related to: Hagedorn Research Institute; Gentofte; Denmark
is related to: Howard Hughes Medical Institute
is related to: Northwestern University; Illinois; USA
is related to: CAMRD
is related to: French National Center for Scientific Research
is related to: University of California at San Diego; California; USA
is related to: University of Pittsburgh; Pennsylvania; USA
is related to: University of Copenhagen; Copenhagen; Denmark
is related to: Jackson Laboratory
is related to: Max Planck Institute for Heart and Lung Research; Bad Nauheim; Germany
is related to: Indiana University; Indiana; USA
is related to: University of Toronto; Ontario; Canada
is related to: Harvard University; Cambridge; United States
is related to: Harvard Medical School; Massachusetts; USA
is related to: Integrated Manually Extracted Annotation
has parent organization: Vanderbilt University; Tennessee; USA
is parent organization of: Beta Cell Genomics Ontology
Type 1 diabetes, Diabetes NIDDK DK-01-014;
NIDDK DK-01-17;
NIDDK DK-01-18;
NIDDK DK-09-011
THIS RESOURCE IS NO LONGER IN SERVICE nlx_144143 SCR_005136 2026-02-15 09:18:55 59

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