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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SPICE
 
Resource Report
Resource Website
50+ mentions
SPICE (RRID:SCR_016603) SPICE data visualization software, data processing software, data analysis software, software application, software resource Software application for data mining and visualization. Used for analyzes of large FLOWJO data sets from polychromatic flow cytometry and organizing the normalized data graphically. data, mining, visualization, analysis, polychromatic, flow, cytometry, dataset, normalized, graphically, bio.tools is listed by: NIAID
is listed by: Debian
is listed by: bio.tools
NIAID ;
NIH
PMID:21265010 Free, Available for download, Freely available biotools:spice https://bio.tools/spice SCR_016603 Simplified Presentation of Incredibly Complex Evaluations 2026-02-14 02:03:15 66
Discovar assembler
 
Resource Report
Resource Website
10+ mentions
Discovar assembler (RRID:SCR_016755) Discovar sequence analysis software, data processing software, data analysis software, software application, software resource Software tool for variant calling with reference and de novo assembly of genomes. The heart of DISCOVAR is a de novo genome assembler which can generate de novo assemblies for both large and small genomes. variant, calling, reference, de novo, assembly, genome, genetic, human, sequence, analysis is listed by: OMICtools
has parent organization: Broad Institute
NHGRI R01 HG003474;
NHGRI U54 HG003067;
NIAID HHSN272200900018C
PMID:25326702 Free, Available for download, Freely available SCR_016755 Discovar de novo, Discovar 2026-02-14 02:03:05 20
SALSA
 
Resource Report
Resource Website
10+ mentions
SALSA (RRID:SCR_022013) data analysis software, software resource, data processing software, software application Software tool for scaffold long read assemblies with Hi-C data. scaffolding, Hi-C data, scaffold long read assemblies NHGRI R44 HG009584;
NIAID R01 AI100947;
Ministry of Health and Welfare ;
Republic of Korea
DOI:10.1371/journal.pcbi.1007273
DOI:10.1186/s12864-017-3879-z
Free, Available for download, Freely available SCR_022013 SALSA2 2026-02-14 02:04:24 40
MCScanX
 
Resource Report
Resource Website
100+ mentions
MCScanX (RRID:SCR_022067) data processing software, data analysis software, software toolkit, software application, software resource Software toolkit for detection and evolutionary analysis of gene synteny and collinearity. gene synteny and collinearity, detection and evolutionary analysis, NSF DBI 0849896;
NSF MCB 0821096;
NSF MCB 1021718;
NIAID R01 AI068908
PMID:22217600 Free, Available for download, Freely available SCR_022067 Multiple Collinearity Scan toolkit X version 2026-02-14 02:04:25 257
Stitchr
 
Resource Report
Resource Website
1+ mentions
Stitchr (RRID:SCR_022139) sequence analysis software, data processing software, data analysis software, software application, software resource Software Python tool for stitching coding T cell receptors nucleotide sequences from V,J,CDR3 information. Produces complete coding sequences representing fully spliced TCR cDNA given minimal V,J,CDR3 information. Stitch together coding TCR nucleotide sequences, Python, T cell receptors nucleotide, V and J gene symbols, hypervariable CDR3 amino acid sequence, fully spliced TCR cDNA NCI R01 CA164273;
NIAID R43 AI120313;
NCI R43 CA232942;
Emily Venanzi Fund
PMID:35325179 Free, Available for download, Freely available SCR_022139 2026-02-14 02:04:43 3
Harmony
 
Resource Report
Resource Website
100+ mentions
Harmony (RRID:SCR_022206) data analysis software, software resource, data processing software, software application Software R package to project cells into shared embedding in which cells group by cell type rather than dataset specific conditions. Harmony simultaneously accounts for multiple experimental and biological factors. Used for integration of single cell data. cells grouping, cell type, experimental factors, biological factors, single cell data integration is used by: harmonypy NIAID U19 AI111224;
NIH R01 AR063759;
NIH UH2 AR067677;
NIH T32 AR007530
PMID:31740819 Free, Available for download, Freely available SCR_022206 Harmony for immunogenomics 2026-02-14 02:04:27 171
ApiDots
 
Resource Report
Resource Website
1+ mentions
ApiDots (RRID:SCR_001778) data or information resource, database Note: ApiDots is currently unavailable. For data on apicomplexan EST assemblies, please see EuPathDB ApiDots is a database integrating mRNA/EST sequences from numerous Apicomplexan parasites. ESTs and mRNAs were clustered and further assembled to generate consensus sequences. These consensus sequences were then subjected to database searches against protein sequences and protein domain sequences. The underlying relational structure of this database allows researchers to analyze these data and pose biologically interesting questions. est, apicomplexan parasite, mrna, protein domain sequence, protein sequence is related to: Eukaryotic Pathogen Database Resources
has parent organization: University of Pennsylvania; Philadelphia; USA
USDA ;
Amerman Family Foundation ;
Merck Research Laboratories ;
Burroughs Wellcome Fund ;
NRI 99-35204-8615;
NIAID AI45806;
NIAID AI45806A1;
NIAID AI48121
PMID:12618375 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-02556 SCR_001778 2026-02-14 02:05:36 2
HIV Molecular Immunology Database
 
Resource Report
Resource Website
1+ mentions
HIV Molecular Immunology Database (RRID:SCR_002893) HIV Molecular Immunology Database data or information resource, database An annotated, searchable collection of HIV-1 cytotoxic and helper T-cell epitopes and antibody binding sites, plus related tools and information. The goal of this database is to provide a comprehensive listing of defined HIV epitopes. These data are also printed in the HIV Molecular Immunology compendium, which is updated yearly and provided free of charge to scientific researchers, both by online download and as a printed copy. The data included in this database are extracted from the HIV immunology literature. HIV-specific B-cell and T-cell responses are summarized and annotated. Immunological responses are divided into three sections, CTL (CD8+), T helper (CD4+), and antibody. Within these sections, defined epitopes are organized by protein and binding sites within each protein, moving from left to right through the coding regions spanning the HIV genome. We include human responses to natural HIV infections, as well as vaccine studies in a range of animal models and human trials. Responses that are not specifically defined, such as responses to whole proteins or monoclonal antibody responses to discontinuous epitopes, are summarized at the end of each protein sub-section. Studies describing general HIV responses to the virus, but not to any specific protein, are included at the end of each section. The annotation includes information such as cross-reactivity, escape mutations, antibody sequence, TCR usage, functional domains that overlap with an epitope, immune response associations with rates of progression and therapy, and how specific epitopes were experimentally defined. Basic information such as HLA specificities for T-cell epitopes, isotypes of monoclonal antibodies, and epitope sequences are included whenever possible. All studies that we can find that incorporate the use of a specific monoclonal antibody are included in the entry for that antibody. A single T-cell epitope can have multiple entries, generally one entry per study. Finally, tables and maps of all defined linear epitopes relative to the HXB2 reference proteins are provided. Alignments of CTL, helper T-cell, and antibody epitopes are available through the search interfaces. Only responses to HIV-1 and HIV-2 are included in the database. cytotoxic t cell, cytotoxic t lymphocyte, helper t-cell, antibody, binding site, epitope, t cell epitope, human immunodeficiency virus, immunology, molecule, genome, protein, alignment, b-cell, t-cell, annotation, ctl, t helper, coding region, cross-reactivity, escape mutation, antibody sequence, tcr usage, functional domain, immune response, progression, therapy has parent organization: HIV Databases Human immunodeficiency virus NIAID nif-0000-02965 http://hiv-web.lanl.gov/immunology/ SCR_002893 Human Immunodeficiency Virus Molecular Immunology Database 2026-02-14 02:05:41 2
Nonhuman Primate HIV/SIV Vaccine Trials Database
 
Resource Report
Resource Website
Nonhuman Primate HIV/SIV Vaccine Trials Database (RRID:SCR_002274) data or information resource, database An overview of HIV and SIV vaccine trials and their outcomes. It was developed as a tool for compilation, search and comparison of published studies on SIV, HIV and SHIV vaccine trials in nonhuman primates. We used a set of criteria to scan Pubmed for relevant studies to enter into the database. In selecting studies for entry, priority was given to recently published studies in journals generally regarded as the primary source of information pertaining to HIV and SIV vaccine research in nonhuman primates. In most cases, we give priority to challenge studies, where the animals received a live virus to measure the "efficacy" of the immunogen(s) inoculated during the course of the investigation. The HIV Sequence Database focuses on five primary goals: *Collecting HIV and SIV sequence data (all sequences since 1987) *Curating and annotating this data, and making it available to the scientific community *Computer analysis of HIV and related sequences *Production of software for the analysis of (sequence) data *Publication of the data and analyses on this site and in a yearly printed publication, the HIV sequence Compendium, which is available free of charge drug, trial, vaccine, human immunodeficiency virus, simian immunodeficiency virus has parent organization: HIV Databases Human immunodeficiency virus, Simian immunodeficiency virus NIAID THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-20999 http://hiv-web.lanl.gov/cgi-bin/vaccine/public/index.cgi SCR_002274 HIV/SIV Trials Vaccine DB, HIV/SIV Trials Vaccine Database 2026-02-14 02:05:47 0
Sparse Inverse Covariance Estimation for Ecological Association Inference
 
Resource Report
Resource Website
10+ mentions
Sparse Inverse Covariance Estimation for Ecological Association Inference (RRID:SCR_022646) SPIEC-EASI software resource, software toolkit Software R package estimates inverse covariance matrix from sequencing data.Statistical method for inference of microbial ecological networks from amplicon sequencing datasets. inverse covariance matrix estimation, sequencing data, microbial ecological networks inference, amplicon sequencing datasets microbial ecological networks, NIAID T32AI007180;
NIDDK R01 DK103358;
NIGMS RO1 GM63270;
Simons Foundation
PMID:25950956 Free, Available for download, Freely available SCR_022646 SParse InversE Covariance Estimation for Ecological Association Inference 2026-02-14 02:07:36 12
SingleR
 
Resource Report
Resource Website
100+ mentions
SingleR (RRID:SCR_023120) software resource, software toolkit Software R package for unbiased cell type recognition of scRNA-seq data. Performs unbiased cell type recognition from single-cell RNA sequencing data, by leveraging reference transcriptomic datasets of pure cell types to infer cell of origin of each single cell independently. unbiased cell type recognition, scRNA-seq data, reference transcriptomic datasets, pure cell types, infer cell of origin UCSF Marcus Award ;
NHLBI HL131560;
UCSF Nina Ireland Program award ;
NHLBI HL139897;
NIAID
PMID:30643263 Free, Available for download, Freely available https://github.com/dviraran/SingleR
https://github.com/LTLA/SingleR
SCR_023120 Single-cell RNA-seq cell types Recognition 2026-02-14 02:07:22 321
DADA2
 
Resource Report
Resource Website
500+ mentions
DADA2 (RRID:SCR_023519) software resource, software toolkit Open source software R package for modeling and correcting Illumina sequenced amplicon errors. Fast and accurate sample inference from amplicon data with single nucleotide resolution. modeling and correcting amplicon errors, Illumina sequenced amplicon errors, amplicon errors, sample inference, amplicon data, single nucleotide resolution is used by: ImmuMicrobiome
is related to: dadasnake
has parent organization: Stanford University; Stanford; California
NSF ;
NIAID R01AI112401;
Samarth Foundation
PMID:27214047 Free, Available for download, Freely available https://bioconductor.org/packages/dada2/ SCR_023519 2026-02-14 02:07:40 960
ATHLATES
 
Resource Report
Resource Website
1+ mentions
ATHLATES (RRID:SCR_023689) software resource, software toolkit Software package for determining HLA genotypes for individuals from Illumina exome sequencing data. Program applies assembly, allele identification and allelic pair inference to short read sequences, and applies it to data from Illumina platforms. Illumina, HLA genotypes determination, Illumina exome sequencing data, allele identification, allelic pair inference, short read sequence, Washington University School of Medicine ;
NIAID ;
National Institutes of Health ;
Department of Health and Human Services
PMID:23748956 Free, Available for download, Freely available SCR_023689 2026-02-14 02:07:37 3
ImmGen
 
Resource Report
Resource Website
100+ mentions
ImmGen (RRID:SCR_021792) data or information resource, database Project combines immunology and computational biology laboratories in effort to establish complete road map of gene-expression and regulatory networks in all immune cells. Project will generate, with rigorously standardized conditions, complete compendium of genome-wide data sets showing expression of protein-coding genes for all defined cell populations of mouse immune system. gene expression, regulatory networks, all immune cells, protein coding genes, mouse immune system NIAID R24 AI072073 PMID:18800157
PMID:32978299
Free, Freely available SCR_021792 Immunological Genome Project 2026-02-14 02:06:56 258
DICOMConvert
 
Resource Report
Resource Website
DICOMConvert (RRID:SCR_014100) software resource, standalone software, software application A DICOM image converter based on the ITK IO mechanism for reading and writing images. The formats currently supported by the converter are DICOM to: Analyze (*.hdr); MetaImage (*.mhd); Nrrd (*.nhdr, *.nrrd). standalone software, dicom, image converter is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: National Institutes of Health
Center for Infectious Disease Imaging ;
NIAID ;
NIBIB
Available for download SCR_014100 Dicom Converter 2026-02-14 02:07:19 0
CIBERSORT
 
Resource Report
Resource Website
1000+ mentions
CIBERSORT (RRID:SCR_016955) data analytics software, software resource, software application Software tool to provide an estimation of the abundances of member cell types in a mixed cell population, using gene expression data. Used for characterizing cell composition of complex tissues from their gene expression profiles, large scale analysis of RNA mixtures for cellular biomarkers and therapeutic targets. estimation, abundance, cell, type, mixed, population, gene, expression, data, tissue, complex, analysis, RNA, biomarker, therapeutic, target, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Stanford University; Stanford; California
Doris Duke Charitable Foundation ;
Damon Runyon Cancer Research Foundation ;
B&J Cardan Oncology Research Fund ;
Ludwig Institute for Cancer Research ;
NCI U01 CA154969;
NIAID U19 AI090019;
NCI T32 CA09302;
US Department of Defense ;
Siebel Stem Cell Institute ;
Thomas and Stacey Siebel Foundation
PMID:25822800 Not freely available for download or distribution, Available for non commercial users, Registration required biotools:CIbERSORt https://bio.tools/CIBERSORT SCR_016955 2026-02-14 02:07:28 1239
Tree-Based Pipeline Optimization Tool
 
Resource Report
Resource Website
1+ mentions
Tree-Based Pipeline Optimization Tool (RRID:SCR_017531) TPOT software resource, software toolkit Software Python package to automate building of ML pipelines by combining flexible expression tree representation of pipelines with stochastic search algorithms such as genetic programming. Automated, machine, learning, optimize, pipeline, genetic, programming NIAID R01 AI117694 Free, Available for download, Freely available SCR_017532 https://epistasislab.github.io/tpot/
https://github.com/EpistasisLab/tpot
SCR_017531 Tree based Pipeline Optimization Tool 2026-02-14 02:07:01 1
ApiDB CryptoDB
 
Resource Report
Resource Website
10+ mentions
ApiDB CryptoDB (RRID:SCR_013455) ApiDB CryptoDB data or information resource, database An integrated genomic and functional genomic database for the parasite Cryptosporidium. CryptoDB integrates whole genome sequence and annotation along with experimental data and environmental isolate sequences provided by community researchers. The database includes supplemental bioinformatics analyses and a web interface for data-mining. Organisms included in CryptoDB are Cryptosporidium parvum, Cryptosporidium hominis, Cryptosporidium muris and environmental isolate sequences from numerous species. CryptoDB is allied with the databases PlasmoDB and ToxoDB via ApiDB, an NIH/NIAID-funded Bioinformatics Resource Center. Tools include: * BLAST: Identify Sequence Similarities * Sequence Retrieval: Retrieve Specific Sequences using IDs and coordinates * PubMed and Entrez: View the Latest Cryptosporidium Pubmed and Entrez Results * Genome Browser: View Sequences and Features in the genome browser * CryptoCyc: Explore Automatically Defined Metabolic Pathways * Searches via Web Services: Web service access to our data cryptosporidium parvum, cryptosporidium, cryptosporidium genome, cryptosporidium orf, cryptosporidium sage tag alignments, cryptosporidium snp, genomic sequence, dna motif, snp, est, orf, data set, bio.tools uses: SynView
is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
has parent organization: Eukaryotic Pathogen Database Resources
NIAID contract HHSN266200400037C PMID:16381902 nif-0000-02698, biotools:cryptodb https://bio.tools/cryptodb http://cryptodb.org/ SCR_013455 CryptoDB, Cryptosporidium Genomics Resource 2026-02-14 02:06:43 25
Cytokine Registry
 
Resource Report
Resource Website
1+ mentions
Cytokine Registry (RRID:SCR_014368) data or information resource, database A registry of cytokines, chemokines, and receptors generated for the purpose of collecting, integrating, and mapping between entity names and synonyms from several resources. These resources include MeSH, the Protein Ontology, EntrezGene, HGNC, MGI, UniProt and others. cytokine, registry, innate immune system, chemokine, receptor uses: UniProt
uses: MeSH
uses: Plant Ontology
uses: Mouse Genome Informatics (MGI)
uses: HGNC
uses: Entrez Gene
is affiliated with: The Immunology Database and Analysis Portal (ImmPort)
has parent organization: University of California at San Francisco; California; USA
NIAID ;
NIH ;
Department of Health and Human Services
Acknowledgement required, Registry file is available for download SCR_014368 ImmPort Cytokine Registry 2026-02-14 02:06:27 1
EPIMHC
 
Resource Report
Resource Website
1+ mentions
EPIMHC (RRID:SCR_016279) data or information resource, database Database of naturally processed MHC-restricted peptide ligands and epitopes for customized computational vaccinology. mhc, peptide, ligand, eiptope, vaccine, vaccinology, virology, t cell, immunogenic, molecule, virus NIAID AI50900;
NIAID AI43649;
Molecular Immunology Foundation
PMID:15657103 Freely available, The research community can contribute to this resource SCR_016279 EPIMHC Database 2026-02-14 02:06:30 4

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