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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
CNVpytor
 
Resource Report
Resource Website
10+ mentions
CNVpytor (RRID:SCR_021627) software application, data processing software, sequence analysis software, data analysis software, software resource Software Python package and command line tool for CNV/CNA analysis from depth of coverage by mapped reads. Software tool for CNV/CNA detection and analysis from read depth and allele imbalance in whole genome sequencing. Copy number variations, copy number alternations, whole genome sequencing, Python has parent organization: Mayo Clinic NCI U24 CA220242 DOI:10.1101/2021.01.27.428472 Free, Available for download, Freely available SCR_021627 2026-02-16 09:50:05 19
Motif Mutation Analysis for Regulatory Genomic Elements
 
Resource Report
Resource Website
500+ mentions
Motif Mutation Analysis for Regulatory Genomic Elements (RRID:SCR_021902) MMARGE software application, data processing software, software toolkit, data analysis software, software resource Software package that integrates genome wide genetic variation with epigenetic data to identify collaborative transcription factor pairs. Optimized to work with chromatin accessibility assays such as ATAC-seq or DNase I hypersensitivity, as well as transcription factor binding data collected by ChIP-seq. Used to identify combinations of cell type specific transcription factors while simultaneously interpreting functional effects of non-coding genetic variation. genome wide genetic variation, epigenetic data, identify collaborative transcription factor pairs, interpreting functional effects, non-coding genetic variation NCI CA173903;
NIGMS GM085764;
NIDDK DK091183;
NHLBI R00 123485
PMID:29893919 Free, Available for download, Freely available SCR_021902 2026-02-16 09:50:11 608
VAMPIRE
 
Resource Report
Resource Website
1+ mentions
VAMPIRE (RRID:SCR_021721) software application, data processing software, data analysis software, image analysis software, software resource Software tool for analysis of cell and nuclear morphology from fluorescence or bright field images. Enables profiling and classification of cells into shape modes based on equidistant points along cell and nuclear contours. Robust method to quantify cell morphological heterogeneity. cell morphology analysis, nuclear morphology analysis, fluorescence images, bright field images NCI U54 CA143868;
NCI R01 CA174388;
NIA P30 AG021334;
NIA U01 AG060903
DOI:10.1038/s41596-020-00432-x Free, Available for download, Freely available SCR_021721 Visually Aided Morpho-Phenotyping Image Recognition 2026-02-16 09:50:08 2
Trans-Institute Angiogenesis Research Program
 
Resource Report
Resource Website
Trans-Institute Angiogenesis Research Program (RRID:SCR_000384) TARP data or information resource, topical portal, resource, portal Trans-NIH program encouraging and facilitating the study of the underlying mechanisms controlling blood vessel growth and development. Other aims include: to identify specific targets and to develop therapeutics against pathologic angiogenesis in order to reduce the morbidity due to abnormal blood vessel proliferation in a variety of disease states; to better understand the process of angiogenesis and vascularization to improve states of decreased vascularization; to encourage and facilitate the study of the processes of lymphangiogenesis; and to achieve these goals through a multidisciplinary approach, bringing together investigators with varied backgrounds and varied interests. blood vessel, growth, development, target, therapeutic, vascularization, angiogenesis, lymphangiogenesis is listed by: NIDDK Information Network (dkNET)
has parent organization: National Institutes of Health
Angiogenesis, Lymphangiogenesis JDRF ;
NEI ;
NHLBI ;
NCI ;
NICHD ;
NIDDK ;
NINDS
THIS RESOURCE IS NO LONGER IN SERVICE nlx_152866 SCR_000384 Trans-Institute Angiogenesis Research Program (TARP) 2026-02-16 09:45:15 0
3D Slicer
 
Resource Report
Resource Website
1000+ mentions
3D Slicer (RRID:SCR_005619) Slicer software application, data processing software, data visualization software, image analysis software, software resource A free, open source software package for visualization and image analysis including registration, segmentation, and quantification of medical image data. Slicer provides a graphical user interface to a powerful set of tools so they can be used by end-user clinicians and researchers alike. 3D Slicer is natively designed to be available on multiple platforms, including Windows, Linux and Mac Os X. Slicer is based on VTK (http://public.kitware.com/vtk) and has a modular architecture for easy addition of new functionality. It uses an XML-based file format called MRML - Medical Reality Markup Language which can be used as an interchange format among medical imaging applications. Slicer is primarily written in C++ and Tcl. birn, diffusion, functional, na-mic (ncbc), nifti-1 support, registration, segmentation, visualization, volume, warping uses: 3DSlicerLupusLesionModule
uses: ShapePopulationViewer
uses: Joint Anisotropic LMMSE Filter for Stationary Rician noise removal in DWI
uses: Joint Anisotropic LMMSE Filter for Stationary Rician noise removal in DWI
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Biositemaps
is related to: Slicer3 Example Modules
is related to: Stereoscopic Atlas of Intrinsic Brain Networks
is related to: VMTK in 3D Slicer
is related to: Diffusion Tractography with Kalman Filter
is related to: Fast Nonlocal Means for MRI denoising
is related to: SpineSegmentation module for 3DSlicer
is related to: BioImage Suite
is related to: NA-MIC Kit
is related to: Hammer And WML Modules for 3D Slicer
is related to: ABC (Atlas Based Classification)
is related to: ARCTIC
is related to: Finsler tractography module for Slicer
is related to: GAMBIT
is related to: GPU based affine registration
is related to: GTRACT
is related to: LEAD-DBS
has parent organization: Harvard University; Cambridge; United States
is parent organization of: Level-set Segmentation for Slicer3
is parent organization of: Slicer3 Module Rician noise filter
has plug in: MultiXplore
works with: UManitoba - JHU Functionally Defined Human White Matter Atlas
works with: SlicerMorph
NIH ;
NCRR ;
NIBIB ;
NCI ;
US Army ;
Telemedicine and Advanced Technology Research Center
3D Slicer License nif-0000-00256 http://www.nitrc.org/projects/slicer SCR_005619 Slicer, 3D Slicer: A multi-platform free and open source software package for visualization and medical image computing, 3D Slicer, 3DSlicer 2026-02-16 09:46:30 2238
GWASdb
 
Resource Report
Resource Website
10+ mentions
GWASdb (RRID:SCR_006015) GWASdb web service, data access protocol, database, software resource, data or information resource Combines collections of genetic variants (GVs) from GWAS and their comprehensive functional annotations, as well as disease classifications. Used to maximize utilility of GWAS data to gain biological insights through integrative, multi-dimensional functional annotation portal. In addition to all GVs annotated in NHGRI GWAS Catalog, we manually curate GVs that are marginally significant (P value < 10-3) by looking into supplementary materials of each original publication and provide extensive functional annotations for these GVs. GVs are manually classified by diseases according to Disease Ontology Lite and HPO (Human Phenotype Ontology) for easy access. Database can also conduct gene based pathway enrichment and PPI network association analysis for those diseases with sufficient variants. SOAP services are available. You may Download GWASdb SNP. (This file contains all of the significant SNP in GWASdb. In the pvalue column, 0 means this P-value is not reported in the study but it is significant SNP. In the source column, GWAS:A represents the original data in GWAS catalog, while GWAS:B is our curation data which P-value < 10-3) genetic variant, genome-wide association study, functional annotation, disease classification, snp, gene, chromosome region, annotation, pathway, protein-protein interaction, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: GWASrap
is related to: Human Phenotype Ontology
is related to: IKMB GWAS Association Testing Pipeline
is related to: GWAS Quality Control Pipeline
is related to: Human Disease Ontology
University of Hong Kong Small Project Fund 201007176262;
Research Grants Council of Hong Kong 781511M;
Research Grants Council of Hong Kong 778609M;
Research Grants Council of Hong Kong N_HKU752/10;
Food and Health Bureau of Hong Kong 10091262;
NCI
PMID:22139925 biotools:gwasdb, nlx_151404 https://bio.tools/gwasdb SCR_006015 2026-02-16 09:46:42 43
Proteome Commons
 
Resource Report
Resource Website
10+ mentions
Proteome Commons (RRID:SCR_006234) Proteome Commons community building portal, data repository, database, storage service resource, software resource, portal, service resource, data or information resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. A public resource for sharing general proteomics information including data (Tranche repository), tools, and news. Joining or creating a group/project provides tools and standards for collaboration, project management, data annotation, permissions, permanent storage, and publication. proteomics, protein, peptide, data sharing, data, tool, news, annotation, proteome, genome is listed by: re3data.org
has parent organization: University of Michigan; Ann Arbor; USA
is parent organization of: Proteome Commons Tranche repository
NCI ;
Clinical Proteomics Technologies for Cancer ;
NCRR P41-RR018627
PMID:20356086 THIS RESOURCE IS NO LONGER IN SERVICE nlx_151800 SCR_006234 ProteomeCommons.org, ProteomeCommons 2026-02-16 09:46:44 12
Natural Products Atlas
 
Resource Report
Resource Website
10+ mentions
Natural Products Atlas (RRID:SCR_025107) NP Atlas knowledge base, data or information resource, atlas Open access knowledge base for microbial natural products discovery. Database of microbially derived natural product structures. Provides coverage of bacterial and fungal natural products to visualize chemical diversity. Includes compounds and contains referenced data for structure, compound names, source organisms, isolation references, total syntheses, and instances of structural reassignment. Interactive web portal permits searching by structure, substructure, and physical properties. Provides mechanisms for visualizing natural products chemical space and dashboards for displaying author and discovery timeline data. Atlas has been developed under FAIR principles. FAIR principles, microbial natural products discovery, natural product structures, bacterial and fungal natural products, visualize chemical diversity, has parent organization: Simon Fraser University; British Columbia; Canada NSERC Discovery ;
NCCIH U41 AT008718;
NIGMS R01 GM125943;
NCCIH F31 AT010098;
NCI F31 CA236237;
NCCIH T32 AT007533;
NIH D43 TW010530;
NSF ;
BBSRC ;
Carnegie Trust for the Universities of Scotland ;
Netherlands eScience Center ;
Sao Paulo Research Foundation ;
NCCIH AT008718;
NIGMS GM124461;
Natural Sciences and Engineering Research Council of Canada ;
Ministry of Science ;
Technology and Telecommunications of Costa Rica
PMID:31807684
DOI:10.1093/nar/gkab941
Free, Freely available, SCR_025107 , The Natural Products Atlas, The Natural Products Atlas 2.0 2026-02-16 09:50:57 19
Sanford Burnham Prebys Medical Discovery Institute Cancer Metabolism Core Facility
 
Resource Report
Resource Website
Sanford Burnham Prebys Medical Discovery Institute Cancer Metabolism Core Facility (RRID:SCR_014873) service resource, core facility, access service resource Facility that aims to investigate role of metabolism in cancer on cellular and organismal level, combining in vitro and in vivo analysis. Comprehensive metabolic facility, including stable isotope tracing and flux analysis. Provides analysis of metabolism using specialist instruments and methodologies, together with advice on planning experiments and analyzing data. All instruments and approaches are available on fee-for-service basis to Cancer Center scientists, but alsoto outside users. Samples for most services can be shipped, but Seahorse analyzer users need to be local so they can bring live cells for analysis. Cancer metabolism, cellular metabolism, metabolism analysis, ABRF is listed by: ABRF CoreMarketplace
is related to: USEDit
has parent organization: Sanford Burnham Prebys Medical Discovery Institute
NCI P30CA030199 Open ABRF_565 https://coremarketplace.org/?FacilityID=565 http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_CancerMetabolism.aspx SCR_014873 SBP Cancer Metabolism Core, Sanford Burnham Prebys Medical Discovery Institute Cancer Metabolism Core, SBP Medical Discovery Institute Cancer Metabolism Core 2026-02-16 09:48:39 0
Salk Institute Razavi Newman Integrative Genomics and Bioinformatics Core Facility (IGC)
 
Resource Report
Resource Website
500+ mentions
Salk Institute Razavi Newman Integrative Genomics and Bioinformatics Core Facility (IGC) (RRID:SCR_014842) SALK IGC, IGC service resource, core facility, access service resource Core facility established to assist the Salk community with integrating genomics data into their research. The primary focus of the core is to provide analysis support for next-generation sequencing applications. core facility, gene, genomic, genomic data, analysis, consultation, applications NCI CA014195;
Helmsley Trust ;
Salk Institute Razavi Newman Integrative Genomics and Bioinformatics Core Facility
Open SCR_014842 , Integrative Genomics, Salk, Core Facility, Institute, Razavi Newman, UCSD, Bioinformatics 2026-02-16 09:48:38 940
scVital
 
Resource Report
Resource Website
scVital (RRID:SCR_026215) software application, software resource, source code Software tool to embed scRNA-seq data into species-agnostic latent space to overcome batch effect and identify cell states shared between species. Deep learning algorithm for cross-species integration of scRNA-seq data. embed scRNA-seq data, species-agnostic latent space, overcome batch effect, identify cell states shared between species, cross-species integration, scRNA-seq data, NIA R01 AG054720;
NCI K08 CA267072;
NCI R01 CA290400;
NCI P30 CA08748
DOI:10.1101/2024.12.20.629285 Free, Available for download, Freely available SCR_026215 2026-02-16 09:51:06 0
DSigDB
 
Resource Report
Resource Website
50+ mentions
DSigDB (RRID:SCR_026202) database, data or information resource Online database provides collection of gene sets based on quantitative inhibition and/or drug-induced gene expression changes data of drugs and compounds. Allows users to search, view and download drugs/compounds and gene sets. gene sets, quantitative inhibition, drug induced, gene expression changes, data, drugs, compounds, NCI P30CA046934;
NCI P50CA058187
PMID:25990557 Free, Freely available, SCR_026202 , Drug Signatures Database, drug SIGnatures DataBase 2026-02-16 09:51:06 82
TRUST4
 
Resource Report
Resource Website
1+ mentions
TRUST4 (RRID:SCR_026162) software application, data processing software, sequence analysis software, data analysis software, source code, software resource Software tool to analyze TCR and BCR sequences using unselected RNA sequencing data, profiled from fluid and solid tissues, including tumors. Performs de novo assembly on V, J, C genes including the hypervariable complementarity-determining region 3 and reports consensus contigs of BCR/TCR sequences. TRUST4 then realigns the contigs to IMGT reference gene sequences to identify the corresponding gene and CDR3 details. TRUST4 supports both single-end and paired-end bulk or single-cell sequencing data with any read length. analyze TCR and BCR sequences, de novo assembly, unselected RNA sequencing data, fluid and solid tissues, tumors, NCI U01CA226196;
NCI U24CA224316
PMID:33986545 Free, Available for download, Freely available SCR_026162 2026-02-16 09:51:06 4
FACETS
 
Resource Report
Resource Website
10+ mentions
FACETS (RRID:SCR_026264) software application, data processing software, data analysis software, source code, software resource Software tool for estimating genome copy numbers from high throughput DNA sequencing data. Allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing. Used to implement Fraction and Copy number Estimate from Tumor/normal Sequencing. Allele-specific copy number, clonal heterogeneity analysis, estimating genome copy numbers, high throughput DNA sequencing data, Fraction and Copy number Estimate from Tumor/normal Sequencing, NCI CA124514;
NCI CA163251;
NCI CA195365;
NCI P01 CA129243;
Susan G. Komen for the Cure ;
NCI P30 CA008748
PMID:27270079 Free, Available for download, Freely available, SCR_026264 2026-02-16 09:51:07 12
Eastern Cooperative Oncology Group Performance Status Scale
 
Resource Report
Resource Website
1+ mentions
Eastern Cooperative Oncology Group Performance Status Scale (RRID:SCR_026432) organization portal, narrative resource, portal, data or information resource, standard specification ECOG Performance Scale describes patient’s level of functioning in terms of their ability to care for themself, daily activity, and physical ability (walking, working, etc.). Standard criteria for measuring how the disease impacts patient’s daily living abilities. Used to assess the functional status of patient. ECOG-ACRIN Cancer Research Group, patient’s performance status, assess patient functional status, conduct clinical trials, NCI Free, Freely available SCR_026432 ECOG Performance Status Scale 2026-02-16 09:51:10 3
MeTPeak
 
Resource Report
Resource Website
10+ mentions
MeTPeak (RRID:SCR_026533) software toolkit, source code, software resource Software package for finding the location of m6A sites in MeRIP-seq data. finding location of m6A sites, MeRIP-seq data NCI P30CA54174;
NCI U54 CA113001;
NIGMS R01 GM113245;
Natural Science Foundation of China ;
NSF
PMID:27307641 Free, Available for download, Freely available SCR_026533 2026-02-16 09:51:11 10
AMICI
 
Resource Report
Resource Website
AMICI (RRID:SCR_026913) software toolkit, source code, software resource Software toolbox implemented in C++/Python/MATLAB that provides efficient simulation and sensitivity analysis routines tailored for scalable, gradient-based parameter estimation and uncertainty quantification. Used for high-performance sensitivity analysis for large ordinary differential equation models. high-performance sensitivity analysis, large ordinary differential equation models, European Unions Horizon 2020 ;
Federal Ministry of Education and Research of Germany ;
German Research Foundation ;
NCI U54 CA225088
PMID:33821950 Free, Available for download, Freely available SCR_026913 Advanced Multilanguage Interface to CVODES and IDAS 2026-02-16 09:51:16 0
OpenTOPAS
 
Resource Report
Resource Website
1+ mentions
OpenTOPAS (RRID:SCR_026927) software application, software resource, source code Software Monte Carlo tool for particle simulation. Used for simulation of medical applications of ionizing radiation with the Monte Carlo method. Allows to assemble and control library of simulation objects (geometry components, particle sources, scorers, etc.) with no need to write C++ code and without knowledge of underlying Geant4 Simulation Toolkit. Monte Carlo method, particle simulation, simulation of medical applications, ionizing radiation, NCI R01 CA140735;
NCI U24 CA215123
PMID:23127075
PMID:32247964
Free, Available for download, Freely available https://opentopas.github.io/ SCR_026927 , TOPAS, TOol for PArticle Simulation 2026-02-16 09:51:17 2
Palantir
 
Resource Report
Resource Website
1+ mentions
Palantir (RRID:SCR_027194) algorithm resource, software resource, source code Algorithm to align cells along differentiation trajectories. Models trajectories of differentiating cells by treating cell fate as probabilistic process and leverages entropy to measure cell plasticity along the trajectory. Generates high-resolution pseudo-time ordering of cells and, for each cell state, assigns probability of differentiating into each terminal state. Trajectory, align cells along differentiation trajectories, NICHD DP1-HD084071;
NCI R01CA164729;
NCI P30 CA008748
PMID:30899105 Free, Available for download, Freely available SCR_027194 2026-02-16 09:51:20 3
RPPA Core Facility
 
Resource Report
Resource Website
10+ mentions
RPPA Core Facility (RRID:SCR_016649) RPPA service resource, core facility, access service resource Core provides technology for functional proteomics studies and centralized, standardized and quality controlled services locally and globally. technology, functional, proteomics, studies, centralized, standardized, quality, controlled, service has parent organization: University of Texas MD Anderson Cancer Center NCI CA16672 Commercially available, Registration required SCR_016649 MD Anderson RPPA Core, RPPA, Reverse Phase Protein Array Core, Reverse Phase Protein Array (RPPA) Core 2026-02-16 09:49:04 34

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