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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
NetCoffee
 
Resource Report
Resource Website
1+ mentions
NetCoffee (RRID:SCR_012095) software resource A fast and accurate algorithm which allows to find a global alignment of multiple protein-protein interaction networks. standalone software, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:24336806 GNU General Public License biotools:netcoffee, OMICS_05172 https://bio.tools/netcoffee SCR_012095 2026-02-14 02:02:35 3
Cell motility
 
Resource Report
Resource Website
Cell motility (RRID:SCR_012120) software resource An open source Java application that provides a clear and concise analysis workbench for large amounts of cell motion data. applet, java, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:16762054 Apache License, v2 biotools:cell-motility, OMICS_05660 https://bio.tools/cell-motility SCR_012120 Cell_motility 2026-02-14 02:02:35 0
ISDTool
 
Resource Report
Resource Website
ISDTool (RRID:SCR_012125) software resource Software that implements a computational model for predicting immunosuppressive domains (ISDs). The software could be used to identify typical ISDs in retroviruses including HERV, HTLV, HIV, STLV, SIV and MLV. standalone software, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:25008418 OMICS_05696, biotools:isdtool https://bio.tools/isdtool SCR_012125 2026-02-14 02:02:18 0
A5-miseq
 
Resource Report
Resource Website
100+ mentions
A5-miseq (RRID:SCR_012148) software resource Software that produces high quality microbial genome assemblies on a laptop computer without any parameter tuning. A5-miseq does this by automating the process of adapter trimming, quality filtering, error correction, contig and scaffold generation, and detection of misassemblies. Unlike the original A5 pipeline, A5-miseq can use long reads from the Illumina MiSeq, use read pairing information during contig generation, and includes several improvements to read trimming. standalone software, illumina, unix/linux, mac os x, bio.tools is used by: Nephele
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:25338718 GNU General Public License OMICS_06339, biotools:a5-miseq https://bio.tools/a5-miseq SCR_012148 2026-02-14 02:02:37 189
PLEK
 
Resource Report
Resource Website
100+ mentions
PLEK (RRID:SCR_012132) software resource An alignment-free software tool which uses a computational pipeline based on an improved k-mer scheme and a support vector machine (SVM) algorithm to distinguish lncRNAs from messenger RNAs (mRNAs), in the absence of genomic sequences or annotations. It is especially suitable for PacBio or 454 sequencing data and large-scale transcriptome data. standalone software, roche, pacific biosciences, unix/linux, c, python, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:25239089 GNU General Public License biotools:plek, OMICS_05839 https://bio.tools/plek SCR_012132 PLEK: predictor of long non-coding RNAs and messenger RNAs based on an improved k-mer scheme 2026-02-14 02:02:10 122
REDItools
 
Resource Report
Resource Website
100+ mentions
REDItools (RRID:SCR_012133) software resource A suite of python scripts to perform high-throughput investigation of RNA editing using next-generation sequencing data. standalone software, illumina, roche, pacific biosciences, life technologies, python, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Google Code
PMID:23742983 MIT License biotools:reditools, OMICS_05860 https://bio.tools/reditools SCR_012133 2026-02-14 02:02:36 141
iceLogo
 
Resource Report
Resource Website
100+ mentions
iceLogo (RRID:SCR_012137) software resource Software that builds on probability theory to visualize significant conserved sequence patterns in multiple peptide sequence alignments against background (reference) sequence sets that can be tailored to the studied system and the used protocol. standalone software, web app, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:19876014 Apache License biotools:icelogo, OMICS_05885 https://bio.tools/icelogo SCR_012137 2026-02-14 02:02:36 176
AMS
 
Resource Report
Resource Website
AMS (RRID:SCR_012140) software resource Software that predicts the wide selection of 88 different types of the single amino acid post-translational modifications (PTM) in protein sequences. The source code and precompiled binaries of brainstorming tool are available under Apache licensing. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:22555647 Apache License OMICS_05934, biotools:ams https://bio.tools/ams SCR_012140 AutoMotif Service 2026-02-14 02:02:11 0
PhosphoSiteAnalyzer
 
Resource Report
Resource Website
PhosphoSiteAnalyzer (RRID:SCR_012142) software resource A bioinformatical software tool for analyzing (quantitative) phosphoproteome datasets. The program retrieves kinase-substrate predictions from NetworKIN and contains various statistical modules for futher analysis. standalone software, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:22471441 Free, Public biotools:phosphositeanalyzer, OMICS_05951 https://bio.tools/phosphositeanalyzer SCR_012142 2026-02-14 02:02:19 0
IsaCGH
 
Resource Report
Resource Website
IsaCGH (RRID:SCR_008375) IsaCGH software resource Software to analyze CNV that will now normalize arrays CGH and it will visually integrate different genome annotations. microarray, array cgh, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
OMICS_00727, biotools:isacgh https://bio.tools/isacgh SCR_008375 2026-02-14 02:01:41 0
G protein receptor interaction feature finding instrument
 
Resource Report
Resource Website
10+ mentions
G protein receptor interaction feature finding instrument (RRID:SCR_008343) production service resource, service resource, analysis service resource, resource Griffin (G-protein-receptor interacting feature finding instrument) is a high-throughput system to predict GPCR - G-protein coupling selectively with the input of GPCR sequence and ligand molecular weight. This system consists of two parts: 1) HMM section using family specific multiple alignment of GPCRs, 2) SVM section using physico-chemical feature vectors in GPCR sequence. G-protein coupled receptors (GPCR), which is composed of seven transmembrane helices, play a role as interface of signal transduction. The external stimulation for GPCR, induce the coupling with G-protein (Gi/o, Gq/11, Gs, G12/13) followed by different kinds of signal transduction to inner cell. About half of distributed drugs are intending to control this GPCR - G-protein binding system, and therefore this system is important research target for the development of effective drug. For this purpose, it is necessary to monitor, effectively and comprehensively, of the activation of G-protein by identifying ligand combined with GPCR. Since, at present, it is difficult to construct such biochemical experiment system, if the answers for experimental results can be prepared beforehand by using bioinformatics techniques, large progress is brought to G-protein related drug design. Previous works for predicting GPCR-G protein coupling selectivity are using sequence pattern search, statistical models, and HMM representations showed high sensitivity of predictions. However, there are still no works that can predict with both high sensitivity and specificity. In this work we extracted comprehensively the physico-chemical parameters of each part of ligand, GPCR and G-protein, and choose the parameters which have strong correlation with the coupling selectivity of G-protein. These parameters were put as a feature vector, used for GPCR classification based on SVM. drug, alignment, biochemical, bioinformatic, coupling, gpcr, g-protein, helix, instrument, interface, ligand, molecular, pattern, physico-chemical, receptor interacting, sequence, signal transduction, stimulation, svm, system, technique, transmembrane, weight, instrument, equipment, hardware, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Computational Biology Research Center Core Facility
National Institute of Advanced Industrial Science and Technology nif-0000-25210, biotools:griffin https://bio.tools/griffin SCR_008343 Griffin 2026-02-14 02:01:37 19
CAT
 
Resource Report
Resource Website
10+ mentions
CAT (RRID:SCR_008421) CAT software resource A repository of tools for analysis and annotation of CAZYmes (Carbohydrate Active enZYmes)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01676, biotools:CAt https://bio.tools/CAT SCR_008421 2026-02-14 02:01:38 13
Generic GO Term Finder
 
Resource Report
Resource Website
100+ mentions
Generic GO Term Finder (RRID:SCR_008870) GOTermFinder, GO-TermFinder, GO Term Finder, GO::TermFinder data processing software, data analysis service, analysis service resource, production service resource, source code, service resource, software application, software resource The Generic GO Term Finder finds the significant GO terms shared among a list of genes from an organism, displaying the results in a table and as a graph (showing the terms and their ancestry). The user may optionally provide background information or a custom gene association file or filter evidence codes. This tool is capable of batch processing multiple queries at once. GO::TermFinder comprises a set of object-oriented Perl modules GO::TermFinder can be used on any system on which Perl can be run, either as a command line application, in single or batch mode, or as a web-based CGI script. This implementation, developed at the Lewis-Sigler Institute at Princeton, depends on the GO-TermFinder software written by Gavin Sherlock and Shuai Weng at Stanford University and the GO:View module written by Shuai Weng. It is made publicly available through the GMOD project. The full source code and documentation for GO:TermFinder are freely available from http://search.cpan.org/dist/GO-TermFinder/. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene ontology, gene, graph, visualization, genomics, gene association, ontology or annotation visualization, term enrichment, ontology, process, function, component, enrichment, bio.tools is listed by: 3DVC
is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Generic Model Organism Database Project
has parent organization: Princeton University; New Jersey; USA
has parent organization: Comprehensive Perl Archive Network
NHGRI 1R01HG002732 PMID:15297299 Free for academic use nlx_149293, biotools_go_term_finder https://bio.tools/go_term_finder SCR_008870 Generic Gene Ontology (GO) Term Finder, Generic Gene Ontology Term Finder 2026-02-14 02:01:39 108
LegumeIP
 
Resource Report
Resource Website
10+ mentions
LegumeIP (RRID:SCR_008906) LegumeIP data analysis service, analysis service resource, data or information resource, production service resource, service resource, database LegumeIP is an integrative database and bioinformatics platform for comparative genomics and transcriptomics to facilitate the study of gene function and genome evolution in legumes, and ultimately to generate molecular based breeding tools to improve quality of crop legumes. LegumeIP currently hosts large-scale genomics and transcriptomics data, including: * Genomic sequences of three model legumes, i.e. Medicago truncatula, Glycine max (soybean) and Lotus japonicus, including two reference plant species, Arabidopsis thaliana and Poplar trichocarpa, with the annotation based on UniProt TrEMBL, InterProScan, Gene Ontology and KEGG databases. LegumeIP covers a total 222,217 protein-coding gene sequences. * Large-scale gene expression data compiled from 104 array hybridizations from L. japonicas, 156 array hybridizations from M. truncatula gene atlas database, and 14 RNA-Seq-based gene expression profiles from G. max on different tissues including four common tissues: Nodule, Flower, Root and Leaf. * Systematic synteny analysis among M. truncatula, G. max, L. japonicus and A. thaliana. * Reconstruction of gene family and gene family-wide phylogenetic analysis across the five hosted species. LegumeIP features comprehensive search and visualization tools to enable the flexible query on gene annotation, gene family, synteny, relative abundance of gene expression. gene function, genome evolution, legume, gene, genome, plant, genomics, transcriptomic, gene annotation, gene family, synteny, gene expression, blast, genomic sequence, microarray, rna-seq, comparative genomics, bio.tools is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is related to: UniProt
is related to: InterProScan
is related to: Gene Ontology
is related to: KEGG
has parent organization: Samuel Roberts Noble Foundation
Samuel Roberts Noble Foundation ;
NSF ABI-0960897
PMID:22110036 biotools:legumeip, nlx_151455 https://bio.tools/legumeip SCR_008906 LegumeIP: an integrative database for comparative genomics and transcriptomics of model legumes, LegumeIP - An Integrative Platform to Study Gene Function and Genome Evolution in Legumes 2026-02-14 02:01:49 19
GMA
 
Resource Report
Resource Website
GMA (RRID:SCR_009212) GMA data processing software, data analysis software, time-series analysis software, software application, software resource Software package to perform Granger mediation analysis for time series. Includes single level GMA model and two-level GMA model, for time series with hierarchically nested structure. Granger, meditation, analysis, time, series, level, GMA, model, BRAIN Initiative, bio.tools is recommended by: BRAIN Initiative
is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: bio.tools
NIBIB EB022911 PMID:31070732 Free, Available for download, Freely available nlx_154361, biotools:GMA https://github.com/chaoning/GMA
https://bio.tools/GMA
http://www.montana.edu/kalinowski/GMA/GMA_Home.htm SCR_009212 Granger Mediation Analysis 2026-02-14 02:01:50 0
TopFIND
 
Resource Report
Resource Website
10+ mentions
TopFIND (RRID:SCR_008918) TopFIND data repository, storage service resource, data or information resource, service resource, database An integrated knowledgebase focused on protein termini, their formation by proteases and functional implications. It contains information about the processing and the processing state of proteins and functional implications thereof derived from research literature, contributions by the scientific community and biological databases. It lists more than 120,000 N- and C-termini and almost 10,000 cleavages. TopFIND is a resource for comprehensive coverage of protein N- and C-termini discovered by all available in silico, in vitro as well as in vivo methodologies. It makes use of existing knowledge by seamless integration of data from UniProt and MEROPS and provides access to new data from community submission and manual literature curating. It renders modifications of protein termini, such as acetylation and citrulination, easily accessible and searchable and provides the means to identify and analyse extend and distribution of terminal modifications across a protein. The data is presented to the user with a strong emphasis on the relation to curated background information and underlying evidence that led to the observation of a terminus, its modification or proteolytic cleavage. In brief the protein information, its domain structure, protein termini, terminus modifications and proteolytic processing of and by other proteins is listed. All information is accompanied by metadata like its original source, method of identification, confidence measurement or related publication. A positional cross correlation evaluation matches termini and cleavage sites with protein features (such as amino acid variants) and domains to highlight potential effects and dependencies in a unique way. Also, a network view of all proteins showing their functional dependency as protease, substrate or protease inhibitor tied in with protein interactions is provided for the easy evaluation of network wide effects. A powerful yet user friendly filtering mechanism allows the presented data to be filtered based on parameters like methodology used, in vivo relevance, confidence or data source (e.g. limited to a single laboratory or publication). This provides means to assess physiological relevant data and to deduce functional information and hypotheses relevant to the bench scientist. TopFIND PROVIDES: * Integration of protein termini with proteolytic processing and protein features * Displays proteases and substrates within their protease web including detailed evidence information * Fully supports the Human Proteome Project through search by chromosome location CONTRIBUTE * Submit your N- or C-termini datasets * Contribute information on protein cleavages * Provide detailed experimental description, sample information and raw data protein, n-termini, c-termini, protease, protein cleavage, proteomics, cleavage site, terminus, modification, proteolytic processing, protein function, domain structure, protein termini, terminus modification, protease, substrate, protease inhibitor, protein interaction, protein-protein interaction, interaction, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: UniProtKB
is related to: PSICQUIC Registry
is related to: MEROPS
has parent organization: University of British Columbia; British Columbia; Canada
Canadian Institutes of Health Research ;
Cancer Research Society ;
British Columbia Proteomics Network ;
Metalloproteinase Proteomics and Systems Biology ;
Michael Smith Foundation for Health Research ;
Breast Cancer Society of Canada ;
Alexander von Humboldt-Stiftung ;
BMBF ;
German Academic Exchange Service
PMID:22102574
PMID:21822272
Public, Acknowledgement requested biotools:topfind, r3d100012721, nlx_151607 https://bio.tools/topfind
https://doi.org/10.17616/R3KB8J
https://doi.org/10.17616/R3KB8J
SCR_008918 Termini oriented protein Function Inferred Database 2026-02-14 02:01:48 29
FGDP
 
Resource Report
Resource Website
FGDP (RRID:SCR_008910) FGDP software resource A Java-based, Microarray or Genechip data analysis system. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Fox Chase Cancer Center
PMID:14734324 GNU General Public License OMICS_00756, biotools:fgdp https://bio.tools/fgdp SCR_008910 Functional Genomics Data Pipeline (FGDP), Functional Genomics Data Pipeline 2026-02-14 02:01:47 0
BeeBase
 
Resource Report
Resource Website
50+ mentions
BeeBase (RRID:SCR_008966) BeeBase data analysis service, analysis service resource, data set, data or information resource, production service resource, service resource, database Gene sequences and genomes of Bombus terrestris, Bombus impatiens, Apis mellifera and three of its pathogens, that are discoverable and analyzed via genome browsers, blast search, and apollo annotation tool. The genomes of two additional species, Apis dorsata and A. florea are currently under analysis and will soon be incorporated.BeeBase is an archive and will not be updated. The most up-to-date bee genome data is now available through the navigation bar on the HGD Home page. genome, gene set, sequence, bee, genomics, entomology, blast, annotation, pest, pathogen, honey, beehive, insect, bee pollen, bee product, bee culture, pollination, pollinator, bio.tools, FASEB list is listed by: re3data.org
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Missouri; Missouri; USA
Texas Agricultural Experiment Station ;
Golden Heritage Foods and Sioux Honey Association ;
NHGRI 5-P41-HG000739-13;
USDA 2008-35302-18804
PMID:21071397 Open unspecified license, Acknowledgement requested, Data Usage Policy nlx_152034, biotools:hgd, r3d100010925 https://bio.tools/hgd
https://doi.org/10.17616/R3Z629
SCR_008966 Hymenoptera Genome Database 2026-02-14 02:01:48 56
R/QTLBIM
 
Resource Report
Resource Website
1+ mentions
R/QTLBIM (RRID:SCR_009375) software resource, software library, software toolkit, software application Software library for QTL Bayesian Interval Mapping that provides a Bayesian model selection approach to map multiple interacting QTL. It works on experimentally inbred lines and performs a genome-wide search to locate multiple potential QTL. The package can handle continuous, binary and ordinal traits. (entry from Genetic Analysis Software) gene, genetic, genomic, r, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
nlx_154597, biotools:qtlbim http://www.ssg.uab.edu/qtlbim/index.jsp
https://cran.r-project.org/src/contrib/Archive/qtlbim/
https://bio.tools/qtlbim
http://www.qtlbim.org/ SCR_009375 2026-02-14 02:01:49 2
Knime4Bio
 
Resource Report
Resource Website
1+ mentions
Knime4Bio (RRID:SCR_005376) Knime4Bio software resource A set of custom nodes for the KNIME (The Konstanz Information Miner) graphical workbench, for analysing next-generation sequencing (NGS) data without the requirement of programming skills. node, next-generation sequencing, knime, bioinformatics, workflow, sequencing, flow, data, bam, wig, bed, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:21984761 GNU General Public License, v3 biotools:knime4bio, OMICS_01143 https://bio.tools/knime4bio SCR_005376 Knime4Bio: custom nodes for the interpretation of Next Generation Sequencing data with KNIME 2026-02-14 02:00:53 2

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