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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
leeHom
 
Resource Report
Resource Website
50+ mentions
leeHom (RRID:SCR_002710) software resource Software program for the Bayesian reconstruction of ancient DNA fragments. The algorithm removes the adaptors and reconstructs the original DNA sequences using a Bayesian maximum a posteriori probability approach. standalone software, illumina, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:25100869 Free, Available for download, Freely available biotools:leehom, OMICS_05254 https://bio.tools/leehom SCR_002710 2026-02-14 02:00:26 53
ANDES
 
Resource Report
Resource Website
10+ mentions
ANDES (RRID:SCR_002791) data processing software, data analysis software, software toolkit, software application, software resource Software library and a suite of applications, written in Perl and R, for deep sequencing statistical analyses. deep sequencing, biomarker detection, statistical analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:20633290 Free, Freely available, Available for download biotools:andes, OMICS_01119 https://bio.tools/andes SCR_002791 Statistical tools for the Analyses of Deep Sequencing (ANDES), Statistical tools for the Analyses of Deep Sequencing, Statistical tools for the ANalyses of Deep Sequencing 2026-02-14 02:00:32 25
NCBI database of Genotypes and Phenotypes (dbGap)
 
Resource Report
Resource Website
500+ mentions
NCBI database of Genotypes and Phenotypes (dbGap) (RRID:SCR_002709) dbGaP data repository, storage service resource, data or information resource, service resource, database Database developed to archive and distribute clinical data and results from studies that have investigated interaction of genotype and phenotype in humans. Database to archive and distribute results of studies including genome-wide association studies, medical sequencing, molecular diagnostic assays, and association between genotype and non-clinical traits. clinical, trial, genotype, interaction, homology, cell, morphology, interaction, phenotype, molecular diagnosis, genetic recombination, gold standard, bio.tools is used by: International Genomics of Alzheimers Project
is used by: NIDDK Inflammatory Bowel Disease Genetics Consortium
is used by: NIH Heal Project
is used by: Genomic Data Commons Data Portal (GDC Data Portal)
is recommended by: National Library of Medicine
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: OMICtools
is listed by: re3data.org
is listed by: NIDDK Information Network (dkNET)
is listed by: bio.tools
is listed by: Debian
is related to: NIDDK Central Repository
is related to: eMERGE Network: electronic Medical Records and Genomics
is related to: Framingham Heart Study
is related to: PhenoExplorer
is related to: Chronic Renal Insufficiency Cohort Study
is related to: DbGaP Cleaner
is related to: Psychiatric Genomics Consortium
is related to: ISCA Consortium
is related to: Allen Institute for Brain Science
has parent organization: NCBI
is parent organization of: Resource for Genetic Epidemiology Research on Adult Health and Aging
NLM PMID:24297256
PMID:17898773
Restricted nif-0000-23342, OMICS_00263, biotools:dbgap, r3d100010788 http://www.ncbi.nlm.nih.gov/sites/entrez?db=gap
https://bio.tools/dbgap
https://doi.org/10.17616/R3GS4K
SCR_002709 database of Genotypes and Phenotypes (dbGaP), dbGaP, NCBI, Database of Genotypes and Phenotypes 2026-02-14 02:00:30 683
Pathview
 
Resource Report
Resource Website
500+ mentions
Pathview (RRID:SCR_002732) software resource A tool set for pathway-based data integration and visualization. It maps and renders a wide variety of biological data on relevant pathway graphs. All users need is to supply their data and specify the target pathway. Pathview automatically downloads the pathway graph data, parses the data file, maps user data to the pathway, and render pathway graph with the mapped data. In addition, Pathview also seamlessly integrates with pathway and gene set (enrichment) analysis tools for large-scale and fully automated analysis. software package, r, differential expression, gene expression, gene set enrichment, genetics, graph, network, metabolomics, microarray, pathway, proteomics, rna-seq, sequencing, systems biology, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23740750 Free, Freely available, Available for download biotools:pathview, OMICS_05212 http://pathview.r-forge.r-project.org/
https://bio.tools/pathview
SCR_002732 path view 2026-02-14 02:00:30 520
SuperPred: Drug classification and target prediction
 
Resource Report
Resource Website
SuperPred: Drug classification and target prediction (RRID:SCR_002691) SuperPred web service, data or information resource, data access protocol, software resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 24,2025. Publicly available web-server to predict medical indication areas based on properties and similarity of chemical compounds. The web-server translates a user-defined molecule into a structural fingerprint that is compared to about 6300 drugs, which are enriched by 7300 links to molecular targets of the drugs, derived through text mining followed by manual curation. Links to the affected pathways are provided. The similarity to the medical compounds is expressed by the Tanimoto coefficient that gives the structural similarity of two compounds. A similarity score higher than 0.85 results in correct ATC prediction for 81% of all cases. As the biological effect is well predictable, if the structural similarity is sufficient, the web-server allows prognoses about the medical indication area of novel compounds and to find new leads for known targets. The combination of physicochemical property and similarity searching provides the possibility to detect new biologically active compounds and novel targets for drug-like compounds. SuperPred can be applied for drug repositioning purposes, too. A further intention of SuperPred is to find side effects elicited by drugs caused through off-target hits. drug, drug class, drug target, addiction, anatomical therapeutic chemical, application area, biological activity, chemical, chemical classification, chemical property, classification, compound, molecular target, molecule, nervous system, pathway, pharmacological property, physicochemical property, prediction, activity spectra, substance, structural similarity, structure, tanimoto coefficient, tanimoto score, target prediction, target-prediction server, therapeutic approach, therapeutic property, drug classification, target prediction, similarity score, target, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Charite - Universitatsmedizin Berlin; Berlin; Germany
SFB 449 ;
IRTG Berlin-Boston-Kyoto and Deutsche Krebshilfe. ;
DFG
PMID:18499712
PMID:24878925
THIS RESOURCE IS NO LONGER IN SERVICE biotools:superpred, nif-0000-00415 https://bio.tools/superpred SCR_002691 2026-02-14 02:00:29 0
Rainbow
 
Resource Report
Resource Website
10+ mentions
Rainbow (RRID:SCR_002724) sequence analysis software, data processing software, data analysis software, software application, software resource Software developed to provide an ultra-fast and memory-efficient solution to clustering and assembling short reads produced by RAD-seq. software, tool, clustering, assembling, short, read, restriction, site, DNA, sequence, analysis, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:22942077
DOI:10.1093/bioinformatics/bts482
Free, Freely available, Available for download SCR_015992, OMICS_03722, biotools:rainbow https://bio.tools/rainbow
https://sources.debian.org/src/bio-rainbow/
SCR_002724 RAD-seq: Restriction-site Associated DNA sequencing, Bio-rainbow, RAD-seq 2026-02-14 02:00:30 41
Coding Potential Calculator
 
Resource Report
Resource Website
100+ mentions
Coding Potential Calculator (RRID:SCR_002764) CPC data analysis service, analysis service resource, production service resource, service resource, software resource A Support Vector Machine-based classifier to assesses the protein-coding potential of a transcript based on six biologically meaningful sequence features. CPC can discriminate coding from noncoding transcripts with high accuracy and speed. In addition to predicting the coding potential of the input transcripts, the CPC web server also graphically displays detailed sequence features and additional annotations of the transcript that may facilitate users' further investigation. The coding potential calculator tool reads FASTA data format as input. fasta, transcript, protein coding, coding potential, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Peking University; Beijing; China
PMID:17631615 Free, Freely available biotools:cpc, rid_000106 https://bio.tools/cpc SCR_002764 2026-02-14 02:00:31 198
rBiopaxParser
 
Resource Report
Resource Website
1+ mentions
rBiopaxParser (RRID:SCR_002744) software resource A software package that provides a comprehensive set of functions for parsing, viewing and modifying BioPAX pathway data within R. At the moment BioPAX level 2 and level 3 are supported. software package, mac os x, unix/linux, windows, data representation, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:23274212 Free, Freely available, Available for download biotools:rbiopaxparser, OMICS_05211 https://github.com/frankkramer/rBiopaxParser
https://bio.tools/rbiopaxparser
SCR_002744 rBiopaxParser - Parses BioPax files and represents them in R 2026-02-14 02:00:19 4
Percolator: Semi-supervised learning for peptide identification from shotgun proteomics datasets
 
Resource Report
Resource Website
1000+ mentions
Percolator: Semi-supervised learning for peptide identification from shotgun proteomics datasets (RRID:SCR_005040) data or information resource, software resource, database Percolator post-processes the results of a shotgun proteomics database search program, re-ranking peptide-spectrum matches so that the top of the list is enriched for correct matches. Shotgun proteomics uses liquid chromatography-tandem mass spectrometry to identify proteins in complex biological samples. We describe an algorithm, called Percolator, for improving the rate of peptide identifications from a collection of tandem mass spectra. Percolator uses semi-supervised machine learning to discriminate between correct and decoy spectrum identifications, correctly assigning peptides to 17% more spectra from a tryptic dataset and up to 77% more spectra from non-tryptic digests, relative to a fully supervised approach. The yeast-01 data is available in tab delimetered format. The SEQUEST parameter file and target database for the yeast and worm data are also available. worm, yeast, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Washington; Seattle; USA
PMID:17952086 biotools:percolator, nlx_98814 https://bio.tools/percolator SCR_005040 Percolator 2026-02-14 02:00:48 2482
MBCluster.Seq
 
Resource Report
Resource Website
1+ mentions
MBCluster.Seq (RRID:SCR_005079) MBCluster.Seq software resource Software to cluster genes based on Poisson or Negative-Binomial model for RNA-Seq or other digital gene expression (DGE) data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24191069 GNU General Public License, >/=v3 OMICS_01417, biotools:mbcluster.seq https://bio.tools/mbcluster.seq SCR_005079 MBCluster.Seq: Model-Based Clustering for RNA-seq Data 2026-02-14 02:00:50 1
GRASS
 
Resource Report
Resource Website
50+ mentions
GRASS (RRID:SCR_005071) GRASS software resource A generic algorithm for scaffolding next-generation sequencing assemblies. next-generation sequencing, scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22492642 GNU General Public License, v3 biotools:GRASS, OMICS_00043 https://bio.tools/GRASS SCR_005071 GRASS: a generic algorithm for scaffolding next-generation sequencing assemblies, GeneRic ASembly Scaffolder 2026-02-14 02:00:48 89
SINA
 
Resource Report
Resource Website
100+ mentions
SINA (RRID:SCR_005067) SINA data analysis service, analysis service resource, production service resource, service resource, software resource Service to align and optionally taxonomically classify your rRNA gene sequences. The results can be combined with any other sequences aligned by SINA or taken from the SILVA databases by concatenation of FASTA files or using the ARB MERGE tool. Note: Submission is currently limited to at most 1000 sequences of at most 6000 bases each. If your requirements exceed this limitation, get Opens internal link in current windowSINA for local installation. alignment, taxonomic classification, rrna, gene sequence, fasta, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: SILVA
is related to: ARB project
has parent organization: Max Planck Institute for Marine Microbiology; Bremen; Germany
PMID:22556368 Free, Available for download, Freely available OMICS_01438, biotools:sina https://bio.tools/sina
https://sources.debian.org/src/sina/
https://github.com/epruesse/SINA
SCR_005067 SINA Alignment Service, SILVA Incremental Aligner 2026-02-14 02:01:02 369
G-BLASTN
 
Resource Report
Resource Website
G-BLASTN (RRID:SCR_005062) G-BLASTN software resource A GPU-accelerated nucleotide alignment tool based on the widely used NCBI-BLAST. It can produce exactly the same results as NCBI-BLAST, and it also has very similar user commands. It also supports a pipeline mode, which can fully utilize the GPU and CPU resources when handling a batch of medium to large sized queries. parallel computation 4, blast, alignment, nucleotide, gpu, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI BLAST
has parent organization: Hong Kong Baptist University; Hong Kong; China
has parent organization: SourceForge
Hong Kong Baptist University; Hong Kong; China FRG2/11-12/158;
NVIDIA
PMID:24463183 Free OMICS_02263, biotools:g-blastn http://sourceforge.net/projects/gblastn/
https://bio.tools/g-blastn
SCR_005062 2026-02-14 02:01:02 0
VFS
 
Resource Report
Resource Website
1+ mentions
VFS (RRID:SCR_005138) VFS software resource A versatile high-throughput sequencing (HTS) tool for discovering viral integration events and reconstruct fusion transcripts at single-base resolution. It combines soft-clipping information, read-pair analysis, and targeted de novo assembly to discover and annotate viral-human fusion events. A simple yet effective empirical statistical model is used to evaluate the quality of fusion breakpoints. Minimal user defined parameters are required. ubuntu, debian, high-throughput sequencing, virus, reconstruct, fusion transcript, transcript, integration, fusion, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Chinese University of Hong Kong; Hong Kong; China
PMID:23314323 GNU General Public License, v3 OMICS_00224, biotools:viralfusionseq https://bio.tools/viralfusionseq SCR_005138 ViralFusionSeq, ViralFusionSeq (VFS) 2026-02-14 02:01:03 1
MMAPPR
 
Resource Report
Resource Website
1+ mentions
MMAPPR (RRID:SCR_005092) MMAPPR software resource A software analysis pipeline for mapping mutations using RNA-seq that works without parental strain information, without the requirement of a pre-existing snp map of the organism, and without erroneous assumptions that recombination occurs at the same frequency across the genome. In addition, it compensates for the considerable amount of noise in RNA-seq datasets and simultaneously identifies the region where the mutation lies and generates a list of putative coding region mutations in the linked genomic segment. MMAPPR can utilize RNA-seq datasets from isolated tissues or whole organisms that are often generated for phenotypic analysis and gene network analysis in novel mutants. mutation, rna-seq, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Utah; Utah; USA
PMID:23299975 Acknowledgement requested OMICS_01361, biotools:mmappr https://bio.tools/mmappr SCR_005092 Mutation Mapping Analysis Pipeline for Pooled RNA-seq 2026-02-14 02:01:02 7
FusionMap
 
Resource Report
Resource Website
50+ mentions
FusionMap (RRID:SCR_005242) FusionMap software resource An efficient fusion aligner which aligns reads spanning fusion junctions directly to the genome without prior knowledge of potential fusion regions. It detects and characterizes fusion junctions at base-pair resolution. FusionMap can be applied to detect fusion junctions in both single- and paired-end dataset from either gDNA-Seq or RNA-Seq studies. FusionMap runs under both Windows and Linux (requiring MONO) environments. Although it can run on 32 bit machine, it is recommended to run on 64-bit machine with 8GB RAM or more. If you have an ArrayStudio License, you can run the fusion detection easily through its GUI. windows, linux, c#, fusion gene, next-generation sequencing, gene, reference indexing, read filtering, fusion alignment, reporting, alignment, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21593131 Free, Non-commercial biotools:fusionmap, OMICS_00316 https://bio.tools/fusionmap SCR_005242 2026-02-14 02:01:05 88
rQuant
 
Resource Report
Resource Website
1+ mentions
rQuant (RRID:SCR_005150) rQuant software resource Software for quantitative detection of alternative transcripts with RNA-Seq data. The method, based on quadratic programming, estimates biases introduced by experimental settings and is thus a powerful tool to reveal and quantify novel (alternative) transcripts. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
PMID:20551130 biotools:rquant.web, OMICS_01286 https://bio.tools/rquant.web SCR_005150 rQuant: quantitative detection of alternative transcripts with RNA-Seq data 2026-02-14 02:01:03 1
ShoRAH
 
Resource Report
Resource Website
10+ mentions
ShoRAH (RRID:SCR_005211) ShoRAH software resource A software package that allows for inference about the structure of a population from a set of short sequence reads as obtained from ultra-deep sequencing of a mixed sample. The package contains programs that support mapping of reads to a reference genome, correcting sequencing errors by locally clustering reads in small windows of the alignment, reconstructing a minimal set of global haplotypes that explain the reads, and estimating the frequencies of the inferred haplotypes. linux, mac os x, windows, next-generation sequencing, c++, python, perl, structure, population, short sequence read, haplotype, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: ETH Zurich; Zurich; Switzerland
PMID:21521499 GNU General Public License, v3 biotools:shorah, OMICS_00231 https://bio.tools/shorah SCR_005211 Short Reads Assembly into Haplotypes, ShoRAH - Short Reads Assembly into Haplotypes 2026-02-14 02:00:50 35
V-Phaser 2
 
Resource Report
Resource Website
1+ mentions
V-Phaser 2 (RRID:SCR_005212) V-Phaser 2 software resource A software tool to call variants in genetically heterogeneous populations from ultra-deep sequence data. It combines information regarding the covariation (i.e. phasing) between observed variants to increase sensitivity and an expectation maximization algorithm that iteratively recalibrates base quality scores to increase specificity. V-Phaser can reliably detect rare variants in diverse populations that occur at frequencies of <1%. V-Phaser 2 is a complete rewrite of the original V-Phaser. It contains a new model for length polymorphisms (indels) and incorporates paired end read information in its phasing model. The data access and probability computation sections of the code have also been highly optimized, resulting in substantial improvements in running time and memory usage. variant, polymorphism, indel, virus, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Broad Institute
NIAID PMID:24088188 Free for academic use, Non-commercial, Http://www.broadinstitute.org/scientific-community/science/projects/viral-genomics/viral-genomics-software-license-v-phaser-2 biotools:v-phaser, OMICS_00232 https://bio.tools/v-phaser SCR_005212 2026-02-14 02:01:03 2
RNA-eXpress
 
Resource Report
Resource Website
1+ mentions
RNA-eXpress (RRID:SCR_005167) RNA-eXpress software resource Software designed as a user friendly solution to extract and annotate biologically important transcripts from next generation RNA sequencing data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Monash University; Melbourne; Australia
PMID:23396121 Acknowledgement requested, Non-Profit biotools:rna-express, OMICS_01285 https://bio.tools/rna-express SCR_005167 2026-02-14 02:01:04 5

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