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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
edgeR
 
Resource Report
Resource Website
10000+ mentions
edgeR (RRID:SCR_012802) edgeR data analysis software, software resource, data processing software, software application Bioconductor software package for Empirical analysis of Digital Gene Expression data in R. Used for differential expression analysis of RNA-seq and digital gene expression data with biological replication. empirical, analysis, digital, gene, expression, data, R, RNA-seq data, bio.tools is used by: Glimma
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: SARTools
is related to: Bioconductor
works with: tximport
NHMRC 406657;
Independent Research Institutes Infrastructure Support Scheme 361646;
Victorian State Government OIS grant ;
Melbourne International Research Scholarship ;
Harris and IBS Honours scholarships
PMID:19910308
DOI:10.1093/bioinformatics/btp616
Free, Available for download, Freely available OMICS_01308, biotools:edger https://bio.tools/edger
https://sources.debian.org/src/r-bioc-edger/
SCR_012802 edgeR, empirical analysis of digital gene expression data in R, Empirical analysis of Digital Gene Expression data in R 2026-02-13 10:57:01 21899
PlasmoDB
 
Resource Report
Resource Website
1000+ mentions
PlasmoDB (RRID:SCR_013331) data repository, storage service resource, web service, data analysis service, analysis service resource, data or information resource, production service resource, service resource, data access protocol, software resource, database Functional genomic database for malaria parasites. Database for Plasmodium spp. Provides resource for data analysis and visualization in gene-by-gene or genome-wide scale. PlasmoDB 5.5 contains annotated genomes, evidence of transcription, proteomics evidence, protein function evidence, population biology and evolution data. Data can be queried by selecting from query grid or drop down menus. Results can be combined with each other on query history page. Search results can be downloaded with associated functional data and registered users can store their query history for future retrieval or analysis.Key community database for malaria researchers, intersecting many types of laboratory and computational data, aggregated by gene. Functional, genomic, database, malaria, parasite, data, analysis, visualization, gene, genome, annotation, transcription, proteomics, protein, evolution, FASEB list uses: SynView
is related to: GeneDB Pfalciparum
has parent organization: Eukaryotic Pathogen Database Resources
has parent organization: Pennsylvania State University
has parent organization: University of Georgia; Georgia; USA
malaria NIAID PMID:18957442 nif-0000-03314, SCR_017665 SCR_013331 PlasmoDB, Plasmodium Genomics Resource, PlasmoDB 5.5, Plasmodium genome-resource 2026-02-13 10:57:06 1239
Neuroimaging in Python
 
Resource Report
Resource Website
10+ mentions
Neuroimaging in Python (RRID:SCR_013141) NIPY, community building portal, portal, software development tool, software development environment, data or information resource, software application, software resource Community site to make brain imaging research easier that aims to build software that is clearly written, clearly explained, a good fit for the underlying ideas, and a natural home for collaboration. brain, imaging, neuroimaging, analysis, python, fmri, fmri analysis, magnetic resonance is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: Python Programming Language
has parent organization: SourceForge
has parent organization: University of California at Berkeley; Berkeley; USA
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
is parent organization of: Dipy
is parent organization of: NiLearn
is parent organization of: NIPY
is parent organization of: NiBabel
is parent organization of: Nipype
is parent organization of: Nitime
NIMH 5R01MH081909-02;
NIBIB 1R03EB008673-01
PMID:21897815 Revised BSD license nlx_149365 http://www.nitrc.org/projects/nipy-community http://www.nitrc.org/projects/nipype SCR_013141 NIPY Community 2026-02-13 10:57:04 24
Computational Biology at ORNL
 
Resource Report
Resource Website
Computational Biology at ORNL (RRID:SCR_005710) Computational Biology at ORNL data analysis service, production service resource, service resource, analysis service resource We are the Computational Biology and Bioinformatics Group of the Biosciences Division of Oak Ridge National Laboratory. We conduct genetics research and system development in genomic sequencing, computational genome analysis, and computational protein structure analysis. We provide bioinformatics and analytic services and resources to collaborators, predict prospective gene and protein models for analysis, provide user services for the general community, including computer-annotated genomes in Genome Channel. Our collaborators include the Joint Genome Institute, ORNL''s Computer Science and Mathematics Division, the Tennessee Mouse Genome Consortium, the Joint Institute for Biological Sciences, and ORNL''s Genome Science and Technology Graduate Program. genetics, research, system development, genomic sequencing, computation, genome analysis, protein structure, analysis, gene, protein, gene annotation, annotation, genome has parent organization: Oak Ridge National Laboratory nlx_149161 SCR_005710 Computational Biology at Oak Ridge National Laboratory, Computational Biology and Bioinformatics Group at ORNL, Computational Biology Bioinformatics Group at ORNL 2026-02-13 10:55:40 0
Expression Profiler
 
Resource Report
Resource Website
1+ mentions
Expression Profiler (RRID:SCR_005821) Expression Profiler data analysis service, production service resource, service resource, analysis service resource THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. The EP:GO browser is built into EBI's Expression Profiler, a set of tools for clustering, analysis and visualization of gene expression and other genomic data. With it, you can search for GO terms and identify gene associations for a node, with or without associated subnodes, for the organism of your choice. other analysis, cluster, analysis, visualization, gene expression, genomic, gene ontology, gene association, microarray, protein-protein interaction, gene, bio.tools is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: European Bioinformatics Institute
European Union ;
Wellcome Trust ;
Estonian Science Foundation 5724;
Estonian Science Foundation 5722
PMID:15215431 THIS RESOURCE IS NO LONGER IN SERVICE biotools:expression_profiler, nlx_149323 https://bio.tools/expression_profiler SCR_005821 Expression Profiler at the EBI 2026-02-13 10:55:42 6
The Guardian: Science
 
Resource Report
Resource Website
The Guardian: Science (RRID:SCR_005166) Guardian: Science data or information resource, narrative resource, blog Latest science news, comment, analysis and features from guardian.co.uk, the world''s leading liberal voice. science, news, comment, analysis, space, medicine, genetics, medical research is used by: NIF Data Federation
is used by: Integrated Blogs
nlx_144198 SCR_005166 2026-02-13 10:55:35 0
Scientific American Observations
 
Resource Report
Resource Website
Scientific American Observations (RRID:SCR_005195) SA Observations data or information resource, narrative resource, blog From the editors and reporters of Scientific American, this blog delivers commentary, opinion and analysis on the latest developments in science and technology and their influence on society and policy. From reasoned arguments and cultural critiques to personal and skeptical takes on interesting science news, you''ll find a wide range of scientifically relevant insights here. commentary, opinion, analysis, science, technology, society, policy is used by: NIF Data Federation
is used by: Integrated Blogs
has parent organization: Scientific American
nlx_144201 SCR_005195 Scientific American - Observations 2026-02-13 10:55:35 0
FuSSiMeG: Functional Semantic Similarity Measure between Gene-Products
 
Resource Report
Resource Website
FuSSiMeG: Functional Semantic Similarity Measure between Gene-Products (RRID:SCR_005738) FuSSiMeG data analysis service, production service resource, service resource, analysis service resource FuSSiMeG is being discontinued, may not be working properly. Please use our new tool ProteinOn. Functional Semantic Similarity Measure between Gene Products (FuSSiMeG) provides a functional similarity measure between two proteins using the semantic similarity between the GO terms annotated with the proteins. Platform: Online tool protein, similarity, gene ontology, gene, ontology, statistical analysis, term enrichment, semantic similarity, analysis, other analysis is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: ProteInOn
has parent organization: University of Lisbon; Lisbon; Portugal
Free for academic use nlx_149198 SCR_005738 Functional Semantic Similarity Measure between Gene-Products, Functional Semantic Similarity Measure between Gene Products (FuSSiMeG) 2026-02-13 10:55:41 0
GOrilla: Gene Ontology Enrichment Analysis and Visualization Tool
 
Resource Report
Resource Website
100+ mentions
GOrilla: Gene Ontology Enrichment Analysis and Visualization Tool (RRID:SCR_006848) GOrilla data analysis service, production service resource, service resource, analysis service resource A tool for identifying and visualizing enriched GO terms in ranked lists of genes. It can be run in one of two modes: * Searching for enriched GO terms that appear densely at the top of a ranked list of genes or * Searching for enriched GO terms in a target list of genes compared to a background list of genes. gene, genetic, ontology, ontology or annotation visualization, statistical analysis, term enrichment, visualization, analysis, protein is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
European Union FP6 ;
Yeshaya Horowitz Association
PMID:19192299 Acknowledgement requested, Free, Public nlx_80425, OMICS_02282 SCR_006848 Gene Ontology enRIchment anaLysis and visuaLizAtion tool, GOrilla: Gene Ontology Enrichment Analysis Visualization Tool 2026-02-13 10:55:56 492
Lists2Networks
 
Resource Report
Resource Website
1+ mentions
Lists2Networks (RRID:SCR_006323) L2N data analysis service, production service resource, service resource, analysis service resource A web-based software system that allows users to upload lists of mammalian genes/proteins onto a server-based program for integrated analysis. The system includes web-based tools to manipulate lists with different set operations, to expand lists using existing mammalian networks of protein-protein interactions, co-expression correlation, or background knowledge co-annotation correlation, as well as to apply gene-list enrichment analyses against many gene-list libraries of prior biological knowledge such as pathways, gene ontology terms, kinase-substrate, microRNA-mRAN, and protein-protein interactions, metabolites, and protein domains. Such analyses can be applied to several lists at once against many prior knowledge libraries of gene-lists associated with specific annotations. The system also contains features that allow users to export networks and share lists with other users of the system. high-throughput sequencing, analysis, gene, protein is listed by: OMICtools
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
PMID:20152038 Free, Public, Account required OMICS_02231 http://www.lists2networks.org SCR_006323 Lists2Networks: Integrated analysis of gene/protein lists 2026-02-13 10:55:48 3
SPIKE
 
Resource Report
Resource Website
100+ mentions
SPIKE (RRID:SCR_010466) SPIKE data or information resource, service resource, database Database of curated human signaling pathways with an associated interactive software tool for analysis and dynamic visualization of pathways. Individual pathway maps can be viewed and downloaded; the entire database may be browsed, or launched via a map viewer tool that allows dynamic visualization of the database and save networks in XGMML format that can be viewed in all generic XGMML viewers. Map Topics * Cell cycle progress and check points * DNA damage response * Programmed cell death related processes * Stress-activated transcription factors * Mitogen-activated protein kinase pathways * Immune response signaling * HEarSpike: hearing related pathways visualization, analysis, cellular, signaling pathway, regulatory network, function, genomic, proteomic, cell cycle, dna damage, cell death, stress, transcription factor, mitogen, protein kinase, pathway, immune response, signaling, hearing, dna damage response, programmed cell death, development, ear, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
is related to: ConsensusPathDB
has parent organization: Tel Aviv University; Ramat Aviv; Israel
Cancer A-T Children's Project ;
Wolfson Foundation ;
European Union FP7 ;
Israel Science Foundation
PMID:21097778
PMID:18289391
biotools:spike, nlx_157705 https://bio.tools/spike SCR_010466 Signaling Pathway Integrated Knowledge Engine 2026-02-13 10:56:42 128
Phenotypes and Mutant Alleles
 
Resource Report
Resource Website
10+ mentions
Phenotypes and Mutant Alleles (RRID:SCR_017523) data or information resource, service resource, database Enables comparative phenotype analysis, searches for human disease models, and hypothesis generation by providing access to spontaneous, induced, and genetically engineered mutations and their strain-specific phenotypes. MGI, phenotype, human, disease, analysis, model, genetically, engineered, mutation, strain, specific, phenotype, data has parent organization: Mouse Genome Informatics (MGI) Free, Freely available SCR_017523 Phenotypes, Alleles & Disease Models 2026-02-13 10:58:04 11
University of Arkansas at Little Rock MidSouth Bioinformatics Center Core Facility
 
Resource Report
Resource Website
University of Arkansas at Little Rock MidSouth Bioinformatics Center Core Facility (RRID:SCR_017168) MidSouth Bioinformatics Center, MBC core facility, software resource, access service resource, service resource Core provides bioinformatics consulting, training, technical assistance, and access to computational infrastructure for faculty, students, and researchers in region with their bioscience computational needs. Offers private sessions, workshops and training on specialty topics. Computing resources including software, computing cluster, technical advice. bioinformatics, assistance, consulting, training, analysis, omic, data has parent organization: University of Arkansas; Arkansas; USA Open SCR_017168 Bioinformatics Center, , University of Arkansas, UA, Core Facility, MBC, UALR, MidSouth, Little Rock 2026-02-13 10:57:52 0
ROIs selection with a non-graphical user interface
 
Resource Report
Resource Website
1+ mentions
ROIs selection with a non-graphical user interface (RRID:SCR_016352) data access protocol, software resource, application programming interface It is non-graphical user interface in MATLAB which relies on keyboard callback functions. Used for analyzing big data sets. non graphical, user, interface, keyboard, callback, function, analysis, big, data, set is related to: MATLAB Free, Available for download, Freely available https://ptrrupprecht.wordpress.com/2015/06/24/a-simple-non-graphical-user-interface-in-matlab-keyboard-callback-functions/ SCR_016352 2026-02-13 10:57:48 2
PlantGSEA
 
Resource Report
Resource Website
10+ mentions
PlantGSEA (RRID:SCR_016866) PlantGSEA data analysis service, production service resource, service resource, analysis service resource Websever for gene set enrichment analysis of plants. Used for interpreting biological meaning of a list of genes by computing the overlaps with various previously defined gene sets. gene, set, enrichement, analysis, plant Ministry of Science and Technology of China ;
Ministry of Education of China
DOI:10.1093/nar/gkt281 SCR_016866 The Plant GeneSet Enrichment Analysis Toolkit, Plant GeneSet Enrichment Analysis, Gene Set Enrichment Analysis (GSEA) 2026-02-13 10:57:47 17
CLC Main Workbench
 
Resource Report
Resource Website
10+ mentions
CLC Main Workbench (RRID:SCR_000354) CLC Main Workbench software resource, software toolkit A suite of software for DNA, RNA and protein sequence data analysis. The software allows for the analysis and visualization of Sanger sequencing data as well as gene expression analysis, molecular cloning, primer design, phylogenetic analyses, and sequence data management. sequencing, analysis, cloning, data, management, molecular, gene, genome, dna, rna is listed by: OMICtools
is listed by: SoftCite
Restricted OMICS_01813 SCR_000354 2026-02-13 10:54:39 31
Acquisition and Analysis for Electron Tomography
 
Resource Report
Resource Website
Acquisition and Analysis for Electron Tomography (RRID:SCR_000192) TOM Toolbox software resource, software toolkit THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. A software platform for low dose electron tomography (ET) for all processing steps: acquisition, alignment, reconstruction, and analysis. Requires: Matlab R2008a and Image Processing Toolbox (V6.1) electron microscope, electron tomography, acquisition, alignment, analysis, processing, reconstruction, software, alignment, reconstruction, processing has parent organization: Max Planck Institute of Biochemistry; Martinsried; Germany PMID:15721576 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10145 http://www.biochem.mpg.de/en/rd/baumeister/tom_e/ SCR_000192 TOM software toolbox 2026-02-13 10:54:38 0
TARGETgene
 
Resource Report
Resource Website
1+ mentions
TARGETgene (RRID:SCR_001392) TARGETgene software resource, software application MATLAB tool to effectively identify potential therapeutic targets and drugs in cancer using genetic network-based approaches. It can rapidly extract genetic interactions from a precompiled database stored as a MATLAB MAT-file without the need to interrogate remote SQL databases. Millions of interactions involving thousands of candidate genes can be mapped to the genetic network within minutes. While TARGETgene is currently based on the gene network reported in (Wu et al.,Bioinformatics 26:807-813, 2010), it can be easily extended to allow the optional use of other developed gene networks. The simple graphical user interface also enables rapid, intuitive mapping and analysis of therapeutic targets at the systems level. By mapping predictions to drug-target information, TARGETgene may be used as an initial drug screening tool that identifies compounds for further evaluation. In addition, TARGETgene is expected to be applicable to identify potential therapeutic targets for any type or subtype of cancers, even those rare cancers that are not genetically recognized. Identification of Potential Therapeutic Targets * Prioritize potential therapeutic targets from thousands of candidate genes generated from high-throughput experiments using network-based metrics * Validate predictions (prioritization) using user-defined benchmark genes and curated cancer genes * Explore biologic information of selected targets through external databases (e.g., NCBI Entrez Gene) and gene function enrichment analysis Initial Drug Screening * Identify for further evaluation existing drugs and compounds that may act on the potential therapeutic targets identified by TARGETgene * Explore general information on identified drugs of interest through several external links Operating System: Windows XP / Vista / 7 disease target, drug discovery, drug, matlab, gene network, genetic interaction, gene, drug screening, mutation driver, therapeutic target, drug candidate, compound, mapping, analysis has parent organization: Biomedical Simulations Resource Cancer NIBIB P41-EB001978 PMID:22952662 Free, Under the terms of a Release Agreement., Please cite nlx_152573 http://bmsr.usc.edu/Software/TARGET/TARGET.html SCR_001392 2026-02-13 10:54:50 7
DPARSF
 
Resource Report
Resource Website
500+ mentions
DPARSF (RRID:SCR_002372) DPARSF data processing software, software resource, software toolkit, software application A MATLAB toolbox forpipeline data analysis of resting-state fMRI that is based on Statistical Parametric Mapping (SPM) and a plug-in software within DPABI. After the user arranges the Digital Imaging and Communications in Medicine (DICOM) files and click a few buttons to set parameters, DPARSF will then give all the preprocessed (slice timing, realign, normalize, smooth) data and results for functional connectivity, regional homogeneity, amplitude of low-frequency fluctuation (ALFF), fractional ALFF, degree centrality, voxel-mirrored homotopic connectivity (VMHC) results. DPARSF can also create a report for excluding subjects with excessive head motion and generate a set of pictures for easily checking the effect of normalization. In addition, users can also use DPARSF to extract time courses from regions of interest. DPARSF basic edition is very easy to use while DPARSF advanced edition (alias: DPARSFA) is much more flexible and powerful. DPARSFA can parallel the computation for each subject, and can be used to reorient images interactively or define regions of interest interactively. Users can skip or combine the processing steps in DPARSF advanced edition freely. magnetic resonance, fmri, resting-state fmri, matlab, analysis, brain is used by: DPABI
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Beijing Normal University; Beijing; China
has parent organization: RFMRI.ORG
PMID:20577591 GNU General Public License nlx_155735 http://www.nitrc.org/projects/dparsf SCR_002372 Data Processing Assistant for Resting-State fMRI 2026-02-13 10:55:01 564
Fusion ICA Toolbox
 
Resource Report
Resource Website
10+ mentions
Fusion ICA Toolbox (RRID:SCR_003494) FIT data processing software, software resource, software toolkit, software application A MATLAB toolbox which implements the joint Independent Component Analysis (ICA), parallel ICA and CCA with joint ICA methods. It is used to to extract the shared information across modalities like fMRI, EEG, sMRI and SNP data. * Environment: Win32 (MS Windows), Gnome, KDE * Operating System: MacOS, Windows, Linux * Programming Language: MATLAB * Supported Data Format: ANALYZE, NIfTI-1 analysis, functional magnetic resonance imaging, cca, image, eeg, neuroimaging, matlab, smri, snp, mri, algorithm, reusable library, independent component analysis, principal component analysis is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Biositemaps
has parent organization: University of New Mexico; New Mexico; USA
NIBIB 1RO1EB005846;
NSF 0612076
GNU General Public License nif-0000-36743 http://www.nitrc.org/projects/fit SCR_003494 Fusion ICA Toolbox (FIT) 2026-02-13 10:55:15 13

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