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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.igb.illinois.edu/corefacilities
Core for biological microscopy and image analysis. Offers high-end equipment,user training,ongoing support, including experiment design and data interpretation,twenty-four hour access Services,3D Printing, Transfer Files, Image Analysis,Histology,Instrument Training.
Proper citation: University of Illinois at Urbana-Champaign Core Facilities at IGB (RRID:SCR_017938) Copy
http://www.scripps.edu/florida/technologies/nmr/index.html
Core provides NMR spectroscopy to researchers in Scripps Research, as well as spectral service to local biotech communities.Facility houses six NMR spectrometers:Bruker AVIII HD 600 NMR spectrometer equipped with 5 mm CPQCI (H-C-N-P) CryoProbe This spectrometer also has 1.7 mm CPTCI (H-C-N) CryoProbe which can be installed upon requested for experiments on micro-gram scale compounds;Bruker AVIII HD 600 NMR spectrometer equipped with 5 mm CPDCH (C-H) CryoProbe. This CryoProbe provides high sensitivity for C-13 NMR experiments;Bruker AV NEO 500 NMR spectrometer with 5 mm BBFO Smart Probe;Bruker AVIII 400 NMR spectrometer equipped with 5 MM BBFO probe ;Bruker AV NEO 399 spectrometer equipped with 5 mm BBFO Smart Probe. All BBFO probes have capabilities to perform NMR experiments on nuclei with resonance frequencies between Ag-109 and P-31, as well as H-1, and F-19.Bruker DPX-400 NMR spectrometer equipped withQ NP (H-F-P-C) probe and B-ACS 120 sample changer.
Proper citation: Scripps Research Institute - Florida Nuclear Magnetic Resonance Core Facility (RRID:SCR_017834) Copy
https://www.microscopyu.com/museum/eclipse-e600
Microscope equipped with CFI60 infinity optical system, providing images in all applications. Incorporates specifications adopted for CFI60 series objectives, including 60 millimeter parfocal distance, 25 millimeter thread size, and standard 22 millimeter field of view. Main components of CFI60 infinity optical system include objective, tube lens to converge light beam, and eyepiece lens to enlarge intermediate image. Fluorescence microscope that has detachable substage, 12 volt 100 watt tungsten halide lamp, filter magazine, and choice of sextuple nosepiece or sextuple DIC nosepiece.Has objectives for brightfield, darkfield, Nomarski DIC, epi fluorescence, or phase contrast techniques.
Proper citation: Nikon Eclipse E600 Fluorescence Microscope (RRID:SCR_018606) Copy
http://www.biotech.ufl.edu/cores/monoclonal-antibody/
Core develops new mouse monoclonal antibodies for investigators to use in basic and applied research.Provided services include immunization of mice, cell fusion, cell cloning, screening by ELISA and Western blot, monoclonal antibody production, purification and labeling, monoclonal antibody analyses such as antibody/antigen affinity measurements, epitope binning and identification of matched antibody pairs. Customer training on select self-service instruments is also offered.
Proper citation: University of Florida ICBR Monoclonal Antibody Core Facility (RRID:SCR_019147) Copy
http://www.biotech.ufl.edu/cores/electron-microscopy/
ICBR Electron Microscopy supports researchers in visualizing microscopic structures through imaging projects and user training. Provided serives include room temperature and cryo transmission and scanning electron microscopy, confocal laser scanning microscopy, sample preparation and user training.
Proper citation: University of Florida ICBR Electron Microscopy Core Facility (RRID:SCR_019146) Copy
https://case.edu/medicine/genomics/
Core provides centralized resource working to take difficulty out of Next Generation Sequencing projects for both novice and experienced users alike. Provides assistance in all facets of experimentation from design to data analysis including grant and manuscript preparations.Offers NGS, Sanger, Informatics and Genotyping services based off of Illumina platform.
Proper citation: Case Western Reserve University Genomics Core Facility (RRID:SCR_019021) Copy
https://www.colorado.edu/center/ciest/
Provides centrally managed experimental testing facility offering geotechnical centrifuge, structural dynamics and materials testing. Facility boasts unique large-scale, fast loading rate, gravitational and environmental control capabilities.
Proper citation: Colorado University at Boulder Center for Infrastructure, Energy, and Space Testing Core Facility (RRID:SCR_018987) Copy
Core provides number of specialized measuring tools for optical and surface characterization, as well as expertise in fiber optics.Fabrication facility is clean room for fabrication at micron and nanometer scale. Training and consultation is provided.
Proper citation: Colorado University at Boulder JILA Keck Lab and Fabrication Core Facility (RRID:SCR_018984) Copy
https://med.virginia.edu/molecular-electron-microscopy-core/
Facility dedicated to high resolution electron cryomicroscopy and electron cryotomography. It houses three electron microscopes,120kV Spirit, 200kV F20, and 300kV Titan Krios. These microscopes are available to researchers either for direct use, or aided by MEMC personnel, to collect data aimed at high resolution structural biology projects.
Proper citation: University of Virginia School of Medicine Molecular Electron Microscopy Core Facility (RRID:SCR_019031) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/nanoimaging/index.html
Provides service and expert advice to researches in their projects related to nanoimaging studies of molecular systems at single molecule and single cell levels utilizing Atomic Force Microscope, combination of Atomic Force Microscope with Fluorescence Optical Microscope, combination of Atomic Force Microscope with Raman Spectroscopy.
Proper citation: University of Nebraska Medical Center Nanoimaging Core Facility (RRID:SCR_018828) Copy
http://www.med.nyu.edu/ocs/cytometry-and-cell-sorting-core
Facility provides cytometry and cell sorting services. Services include immunophenotyping, cell cycle analysis, and intracellular fluorophore detection. Services can be tailored to research needs, certified cytometrists are available to help plan experiments. Offers online and hands-on training in use of cell analyzers and analysis software.
Proper citation: New York University School of Medicine Langone Cytometry and Cell Sorting Core Facility (RRID:SCR_018827) Copy
https://labnodes.vanderbilt.edu/vger
Provides services, consultation, and collaborations to enable generation, storage and regeneration of genetically altered mice.Services include CRISPR-Cas9 Mouse Editing, Pronuclear Microinjection of DNAs,Sperm or Embryo Cryopreservation,In vitro Fertilization and Rederivation,Genome-Editing Design and Analysis Services.
Proper citation: Vanderbilt University Genome Editing Resource Core Facility (RRID:SCR_018826) Copy
https://research.uky.edu/abebc
Core primary focus is to identify mechanisms linking obesity to cardiovascular disease. Provides equipment and technical expertise for measurement of lean/fat mass and whole body metabolism in mice. Provides equipment for computerized quantitative measurement of oxygen consumption, food intake, water intake, and physical activity in mice.Echo MRI is utilized for non invasive quantitative assessment of lean and fat mass.
Proper citation: Kentucky University, Lexington, Energy Balance and Body Composition Core Facility (RRID:SCR_018825) Copy
https://www.biotech.iastate.edu/Hybridoma/
Core provides services for monoclonal or polyclonal antibodies production,animal immunization, cell fusion and hybridoma culture maintenance, cell culture and maintenance of other cell lines used in biotechnology and virology labs, large scale mammalian cell culture (bioreactor), blood sera collection, antibody purification and isotyping, cryopreservation and cryostorage of cell lines, and ELISA tests.
Proper citation: Iowa State University Hybridoma Core Facility (RRID:SCR_018829) Copy
https://www.danforthcenter.org/our-work/core-facilities/advanced-bioimaging-laboratory/
Core provides instruments for live cell imaging including Leica SP8-X confocal microscope and other fluorescence microscopes. Facility provides workstation for confocal image processing, ancillary equipment required for transmission electron microscopy. Services are provided as self services after user training by IMF staff or as full services done by core facility staff.
Proper citation: Donald Danforth Plant Science Center Advanced Bioimaging Laboratory Core Facility (RRID:SCR_018951) Copy
https://isb3d.pharmacy.vcu.edu/resources/
Core provides services for Molecular Modeling, Biophysical Techniques, X-ray Crystallography, Protein Production,High Throughput Screening. Provided instruments to use after reservation include Clariostar Multimode Plate Reader, Echo 550 Acoustic Liquid Handler, X-Ray Diffractometer.
Proper citation: Virginia Commonwealth University School of Pharmacy Institute for Structural Biology, Drug Discovery and Development Core Facility (RRID:SCR_018832) Copy
Provides development and support of genomics-based research, serving investigators in Nevada and beyond. Staff can be contracted for select services including ABI 3130 DNA sequencing, BD FACSCalibur flow cytometry, Affymetrix microarray processing, Agilent 2100 Bioanalyzer analysis and Qubit analysis. Facility also provides equipment and training for real-time PCR, Western blot/gel/microarray scanning, and analysis of DNA, RNA and protein samples.
Proper citation: Nevada University Genomics Core Facility (RRID:SCR_018272) Copy
Contract Research Org. specializing in custom protein analysis. Services Provided include SDS PAGE analysis, Western Blotting, Mass Spectrometry, protein staining ( silver,coomassie) for academia, federal institutions and industry.
Proper citation: Kendrick Labs Core Facility (RRID:SCR_018271) Copy
Core provides scientific consultation, training and access to shared biophysical equipment for characterization and analysis of macromolecules and their complexes. Facility includes instruments measuring molecular interactions and assessing protein quality by Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), MicroScale Thermophoresis (MST), Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), Analytical Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS), and Dynamic Light Scattering (DLS).
Proper citation: Harvard Medical School Center for Macromolecular Interactions Core Facility (RRID:SCR_018270) Copy
Core assists investigators whose research requires molecular marker characterization of cells in suspension as well as isolation of cells based on those markers. Advanced cell sorting and cytometric analyses by Flow or Mass Cytometry are provided.
Proper citation: University of California San Francisco Parnassus Flow Cytometry Core Facility (RRID:SCR_018206) Copy
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