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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://research.manchester.ac.uk/en/equipments/corrosion-amp-materials-for-demanding-environments
Core includes facilities and techniques, supporting exploration of this unique research space. Provides expertise and services for advanced materials and interdisciplinary research activity.
Proper citation: University of Manchester Corrosion and Materials for Demanding Environments Core Facility (RRID:SCR_024787) Copy
https://research.manchester.ac.uk/en/equipments/surface-characterisation
Core includes range of surface analysis techniques and supportive instruments across three research institutes: Henry Royce Institute, Photon Science Institute, and National Graphene Institute.
Proper citation: University of Manchester Surface Characterisation Core Facility (RRID:SCR_024789) Copy
https://biotech.unl.edu/flow-cytometry#tab1
Provides flow cytometry services. Instruments include Beckman Coulter CytoFLEX SRT sorter and CytoFLEX LX, as well as NanoAnalyzer from NanoFCM. Facility staff are able to assist with everything from experimental design, instrument training, sample collection, and data analysis.
Proper citation: University of Nebraska Lincoln Flow Cytometry Core Facility (RRID:SCR_024711) Copy
https://research.lsuhs.edu/cores/research-core-facilities
Core provides access to research services, educational and training opportunities, and technologies including cellular metabolism, flow cytometry, fluorescence, confocal, super resolution confocal microscopy, next generation sequencing, and real-time PCR. Provides assistance with all aspects of these technologies, including experimental design, protocol optimization, instrument operation, and data analysis.
Proper citation: Louisiana State University in Shreveport Research Core Facility (RRID:SCR_024775) Copy
https://research.manchester.ac.uk/en/equipments/design-fabrication-and-testing
Core supports areas of research from Heavy Structures and Concrete design, fabrication and testing to Non-Destructive Testing, development and construction of novel fibre, polymers and composite materials.
Proper citation: University of Manchester Design, Fabrication and Testing Core Facility (RRID:SCR_024801) Copy
https://www.cincinnatichildrens.org/research/support/schubert-clinic/services/bionutrition
Facility works with investigators to obtain and analyze high-quality nutrition and body composition data from study participants. Staff and facilities are located in the Schubert Research Clinic at Cincinnati Childrens Hospital. Core provides diet assessment services.
Proper citation: Cincinnati Children's Hospital Bionutrition Research Core Facility (RRID:SCR_024780) Copy
https://research.manchester.ac.uk/en/equipments/x-ray-diffraction-platform
Core to bring together community of knowledge and best practise from three Faculty of Science and Engineering Departments: Chemistry, EES and Materials. Provided equipment is housed across numerous parts of campus with bulk being operated from Engineering Building A and Chemistry. Offers technical expertise in techniques such as residual stress analysis, texture analysis, phase identification in crystalline and semi crystalline powders and solid materials, single crystal and small angle scattering. Machines are available for examination of both small specimens and large components, and for wide range of materials.
Proper citation: University of Manchester X-ray Diffraction Platform Core Facility (RRID:SCR_024785) Copy
https://noncodingrna.org/detection-unit/
Detection Unit of ncRNA Core can perform highly sensitive microRNA detection platform for diverse biospecimens.Technology is based on qPCR and uses single plate panel for simultaneous detection of 384 miRNAs using MIRXES technology. Services offered by unit include Detection of miRNA, Analysis of dysregulated miRNA,Consultation and support for non-coding RNA biology and research.
Proper citation: Beth Israel Deaconess Medical Center Precision RNA Medicine Detection Unit Core Facility, (RRID:SCR_024819) Copy
https://research.lsuhs.edu/cores/research-core-facilities/small-animal-imaging-facility
Core provides imaging support to investigators who use small animal models in their research. Offers bioluminescence and fluorescence imaging, X-ray imaging, computed tomography, and positron emission tomography. Core provides imaging support services for investigators, including assistance in experimental design, conducting animal studies including anesthetization and imaging acquisition, and processing and interpreting imaging data.
Proper citation: Louisiana State University in Shreveport Small Animal Imaging Core Facility (RRID:SCR_024777) Copy
https://www.lsuhs.edu/centers/cardiovascular-diseases-and-sciences/cobre/cobre-core-facilities
Facility includes Analytic Redox Biology and Molecular Signaling Sub-Cores. Provided services include measurements of reactive oxygen species, reactive nitrogen species, reactive sulfide species, protein, peptides, metabolites, and lipids in cell culture and tissue samples. High-performance liquid chromatography systems, coupled with UV-vis and fluorescence detectors to quantify cellular and mitochondrial superoxide production, hydrogen sulfide pools (free sulfide, sulfide bound to transitional metals, and sulfane sulfur), and thiols (glutathione, GSH/GSSG, cysteine, cystine, homocysteine, persulfides, and glutathionylation).Instruments include Sievers NO Analyzer (NOA 280i, GE), Agilent 8890 GC and 8335 sulfur chemiluminescence detector ,Thermo Scientific Orbitrap Exploris 480 and SCIEX Triple Quad 7500 mass spectrometer. Molecular Signaling Sub-Core offers services for molecular cloning and site-directed mutagenesis, design and production of vectors for CRISPR/Cas9 modification of vascular cells, services for endothelial, smooth muscle, and cardiac myocyte cell isolation, for generation of vascular cell lines, and for lentivirus production for transient or stable modification of cardiovascular cells, access to equipment and expertise for studying cellular effects of hypoxia/reoxygenation injury (Coy Hypoxic Chamber, CLARIOstar Spectrofluorometer), for automated capillary Western blot analysis (ProteinSimple Jess Simple Western), and for high-resolution fluo-respirometry to study mitochondrial function (Oroboros O2k modular system).
Proper citation: Louisiana State University in Shreveport Redox Molecular Signaling Core Facility (RRID:SCR_024778) Copy
Core supports data analysis, network modeling, and data science research. Provides training and education opportunities.
Proper citation: Louisiana State University in Shreveport CAIPP Bioinformatics and Modeling Core Facility (RRID:SCR_024779) Copy
https://snyder.ucalgary.ca/labs/live-cell-imaging/LCIoverview
Offers advanced imaging technology, as well as training and support personalized to their imaging goals and experience. Provides Technology access and training; Assisted imaging and coaching at every step of the imaging workflow, from sample preparation to data analysis; Pilot experiments and feasibility testing; Developing custom image analysis pipelines; Image analysis consultation and training; Developing and testing new instruments and devices; Full scientific and technological collaborations and partnerships; Offsite coaching, assistance and consulting ; Collaborative projects in academic, health and allied industrial sectors;
Proper citation: University of Calgary Live Cell Imaging Laboratory Core Facility (RRID:SCR_024748) Copy
https://www.medschool.umaryland.edu/cibr/core/tgl/
Core provides range of genomics technologies to support basic, translational, and clinical research.Services support basic research. Clinical assays offered are similar to those offered to support basic research, except that these assays are validated under CLIA, enabling them to be used in clinical decision making process in research protocols and for routine patient care.
Proper citation: University of Maryland School of Medicine Translational Genomics Laboratory Core Facility (RRID:SCR_024749) Copy
https://www.uml.edu/research/crf/ourlabs/therm-mech-prop-lab.aspx
Core houses thermal analysis suite. Researchers are able to investigate behavior of material under stress and temperature change. Service level work and technical expertise are provided.
Proper citation: University of Massachusetts Lowell Thermal and Mechanical Properties Lab Core Facility (RRID:SCR_024980) Copy
https://www.uml.edu/research/crf/ourlabs/next-gen-sequencing-lab.aspx
Core provides Next-Generation DNA and RNA sequencing services and technical expertise including NGS library prep, DNA and RNA quality assessment, Fluorometric quantification of DNA/RNA/Protein, DNA and RNA isolation, PCR/qPCR, Qubit fluorometry, gene expression and drug development studies. Consultative services are available.
Proper citation: University of Massachusetts Lowell Next Generation Sequencing and Genomics Core Facility (RRID:SCR_024981) Copy
https://www.bidmc.org/research/core-facilities/ncrna-core
Delivery Unit offers training and services on the NanoAssemblr Spark, NanoAssemblr Ignite+, and Malvern Zetasizer for the purpose of synthesis and characterisation of Lipid Nanoparticles (LNPs). The Zetasizer is able to read zeta potential and size of particles, including exosomes, liposomes, and LNPs.
Proper citation: Beth Israel Deaconess Medical Center Precision RNA Medicine Delivery Unit Core Facility (RRID:SCR_024862) Copy
https://www.wistar.org/our-science/shared-facilities/molecular-screening-protein-expression-facility
Facility enables to discover molecular, genetic, and small molecule compounds suitable to study functions of poorly understood proteins, signaling pathways, and cells in complex biological processes relevant to human physiology and disease; provides technical assistance with viral vector preparation and expression and purification of recombinant proteins; fosters collaborations. Staff will also develop and implement new technology as needed. Education and training is also available. Provides opportunities to develop new innovative basic and translational research, preliminary data for hypothesis driven research grant applications, and public-private partnerships.
Proper citation: Wistar Institute Molecular Screening and Protein Expression Core Facility (RRID:SCR_024978) Copy
https://www.uml.edu/research/crf/ourlabs/nuc-mag-res-lab.aspx
Core provides JEOL 400 MHz NMR equipped with auto sampling and automatic tuning and matching. Instrument can perform temperature and kinetic studies as well as x-nuclei and 2D experiments.
Proper citation: University of Massachusetts Lowell Nuclear Magnetic Resonance Spectroscopy Lab Core Facility (RRID:SCR_024979) Copy
Core for proteomics technology development and service. Provides mass spectrometry analytical services to academic, industrial, and government laboratories.
Proper citation: University of Victoria Genome BC Proteomics Centre Core Facility (RRID:SCR_024904) Copy
https://www.baderc.org/cores/functional-genomics-and-bioinformatics-core/
Core provides consultative, laboratory, and bioinformatic services for next generation sequencing based applications.Core services include Pre- and post-experimental consultation to determine proper experimental approach, design, and interpretation; Standalone RNA preparation, RNA and DNA Bioanalyzer analyses, chromatin shearing/shear checks; Sample quality assessment of DNA and RNA using the BioAnalyzer and Qubit assays; Library preparation, sequencing, and analysis of transcriptomes (RNA-seq), cistromes (ChIP-seq), chromatin accessibility (ATAC-seq); Standalone sequencing on NextSeq500; Multiplexed 10x Single Cell/Nucleus Library RNA-seq Droplet generation, Library Preparation; Basic data analysis: quality assessment and normalization, genomic alignment, differential expression/enrichment, functional enrichment analysis (overrepresentation and GSEA), sample clustering, and motif enrichment; Bespoke data analysis, including integration of complex ChIP-seq and RNA-seq data sets, single-cell sequencing analyses.Core is located on the 7th floor of the Center for Life Sciences building in the Longwood Medical area (3 Blackfan Circle, CLS-728).
Proper citation: Beth Israel Deaconess Medical Center Functional Genomics and Bioinformatics Core Facility (RRID:SCR_024877) Copy
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