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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
mrCaNaVaR
 
Resource Report
Resource Website
10+ mentions
mrCaNaVaR (RRID:SCR_003135) mrCaNaVaR software resource Copy number caller that analyzes the whole-genome next-generation sequence mapping read depth to discover large segmental duplications and deletions. It also has the capability of predicting absolute copy numbers of genomic intervals. genome, next-generation sequence, duplication, deletion, copy number variant, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: SPLITREAD
has parent organization: SourceForge
Free, Freely available OMICS_02138, nlx_156790, biotools:mrcanavar https://bio.tools/mrcanavar SCR_003135 mrCaNaVaR - micro-read Copy Number Variant Regions, micro-read Copy Number Variant Regions 2026-02-14 02:00:40 14
SplicingCompass
 
Resource Report
Resource Website
1+ mentions
SplicingCompass (RRID:SCR_003249) sequence analysis software, data processing software, data analysis software, software application, software resource Software for detection of differential splicing between two different conditions using RNA-Seq data. differential splicing, splicing event, exon removal, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:23449093 Free, Available for download, Freely available biotools:splicingcompass, OMICS_01340 https://github.com/KoenigLabNM/SplicingCompass SCR_003249 Splicing Compass 2026-02-14 02:00:43 2
MultiLoc
 
Resource Report
Resource Website
10+ mentions
MultiLoc (RRID:SCR_003151) MultiLoc data analysis service, analysis service resource, production service resource, service resource, software resource An extensive high-performance subcellular protein localization prediction system that incorporates phylogenetic profiles and Gene Ontology terms to yield higher accuracies compared to its previous version. Moreover, it outperforms other prediction systems in two benchmarks studies. A downloadable version of MultiLoc2 for local use is also available. subcellular localization, protein, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Tubingen; Tubingen; Germany
PMID:19723330 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01628, biotools:multiloc2 https://bio.tools/multiloc2 SCR_003151 2026-02-14 02:00:41 40
Primer3
 
Resource Report
Resource Website
10000+ mentions
Primer3 (RRID:SCR_003139) Primer3 data analysis service, analysis service resource, production service resource, service resource, software resource Tool used to design PCR primers from DNA sequence - often in high-throughput genomics applications. It does everything from mispriming libraries to sequence quality data to the generation of internal oligos. primer, primer design, polymerase chain reaction, pcr primer, dna sequence, c, perl, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Primer3Plus
is related to: Primer-BLAST
has parent organization: University of Tartu; Tartu; Estonia
NHGRI R01-HG00257;
NHGRI P50-HG00098
PMID:22730293
PMID:17379693
DOI:10.1385/1-59259-192-2:365
DOI:10.1385/1-59259-192-2:365
Free, Freely available nlx_156833, OMICS_02325, biotools:primer3 http://bioinfo.ut.ee/primer3-0.4.0/
http://sourceforge.net/projects/primer3/
http://frodo.wi.mit.edu/primer3
https://bio.tools/primer3
https://sources.debian.org/src/primer3/
https://sources.debian.org/src/primer3/
SCR_003139 Primer3web - Pick primers from a DNA sequence, Primer3 - PCR primer design tool, Primer3web 2026-02-14 02:00:41 10957
Mouse Phenome Database (MPD)
 
Resource Report
Resource Website
100+ mentions
Mouse Phenome Database (MPD) (RRID:SCR_003212) MPD experimental protocol, data repository, storage service resource, data or information resource, service resource, narrative resource, database Database enables integration of genomic and phenomic data by providing access to primary experimental data, data collection protocols and analysis tools. Data represent behavioral, morphological and physiological disease-related characteristics in naive mice and those exposed to drugs, environmental agents or other treatments. Collaborative standardized collection of measured data on laboratory mouse strains to characterize them in order to facilitate translational discoveries and to assist in selection of strains for experimental studies. Includes baseline phenotype data sets as well as studies of drug, diet, disease and aging effect., protocols, projects and publications, and SNP, variation and gene expression studies. Provides tools for online analysis. Data sets are voluntarily contributed by researchers from variety of institutions and settings, or retrieved by MPD staff from open public sources. MPD has three major types of strain-centric data sets: phenotype strain surveys, SNP and variation data, and gene expression strain surveys. MPD collects data on classical inbred strains as well as any fixed-genotype strains and derivatives that are openly acquirable by the research community. New panels include Collaborative Cross (CC) lines and Diversity Outbred (DO) populations. Phenotype data include measurements of behavior, hematology, bone mineral density, cholesterol levels, endocrine function, aging processes, addiction, neurosensory functions, and other biomedically relevant areas. Genotype data are primarily in the form of single-nucleotide polymorphisms (SNPs). MPD curates data into a common framework by standardizing mouse strain nomenclature, standardizing units (SI where feasible), evaluating data (completeness, statistical power, quality), categorizing phenotype data and linking to ontologies, conforming to internal style guides for titles, tags, and descriptions, and creating comprehensive protocol documentation including environmental parameters of the test animals. These elements are critical for experimental reproducibility. female, genomic location, genotype, inbred strain, male, mouse strain, phenome, phenotype, qtl, reference data, single-nucleotide polymorphism, strain allele, strain characteristic, strain, trait, gene expression, variation, hypothesis testing, data set, bio.tools, FASEB list is used by: NIF Data Federation
is used by: Integrated Datasets
is used by: NIH Heal Project
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: Special Mouse Strains Resource
is related to: Vertebrate Trait Ontology
is related to: GenomeMUSter
has parent organization: Jackson Laboratory
NIDA ;
NHGRI HG003057;
NHLBI HL66611;
NIA AG025707;
NIA AG038070;
NIMH MH071984;
NIDA DA028420
PMID:24243846
PMID:22102583
PMID:18987003
PMID:17151079
Free, Freely available biotools:mpd, nif-0000-03160, r3d100010101 https://bio.tools/mpd
https://doi.org/10.17616/R3PC7F
http://www.jax.org/phenome SCR_003212 Mouse Phenome Database 2026-02-14 02:00:42 221
Pipeliner
 
Resource Report
Resource Website
1+ mentions
Pipeliner (RRID:SCR_003171) software resource Software for evaluating the performance of bioinformatics pipelines for Next Generation re-Sequencing. standalone software, c++, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24890372 Free, Available for download, Freely available OMICS_04844, biotools:pipeliner https://bio.tools/pipeliner SCR_003171 2026-02-14 02:00:30 6
Database of Interacting Proteins (DIP)
 
Resource Report
Resource Website
100+ mentions
Database of Interacting Proteins (DIP) (RRID:SCR_003167) DIP data repository, storage service resource, data analysis service, analysis service resource, data or information resource, production service resource, service resource, database Database to catalog experimentally determined interactions between proteins combining information from a variety of sources to create a single, consistent set of protein-protein interactions that can be downloaded in a variety of formats. The data were curated, both, manually and also automatically using computational approaches that utilize the the knowledge about the protein-protein interaction networks extracted from the most reliable, core subset of the DIP data. Because the reliability of experimental evidence varies widely, methods of quality assessment have been developed and utilized to identify the most reliable subset of the interactions. This CORE set can be used as a reference when evaluating the reliability of high-throughput protein-protein interaction data sets, for development of prediction methods, as well as in the studies of the properties of protein interaction networks. Tools are available to analyze, visualize and integrate user's own experimental data with the information about protein-protein interactions available in the DIP database. The DIP database lists protein pairs that are known to interact with each other. By interact they mean that two amino acid chains were experimentally identified to bind to each other. The database lists such pairs to aid those studying a particular protein-protein interaction but also those investigating entire regulatory and signaling pathways as well as those studying the organization and complexity of the protein interaction network at the cellular level. Registration is required to gain access to most of the DIP features. Registration is free to the members of the academic community. Trial accounts for the commercial users are also available. blast, cellular network, ligand-receptor complex, ligand, network, protein, protein interaction, protein ligand, protein-protein interaction, protein receptor, receptor, sequence, interaction, regulatory pathway, signaling pathway, protein binding, bio.tools, FASEB list is recommended by: NIDDK Information Network (dkNET)
is recommended by: National Library of Medicine
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: OMICtools
is listed by: re3data.org
is listed by: NIH Data Sharing Repositories
is listed by: bio.tools
is listed by: Debian
is related to: IMEx - The International Molecular Exchange Consortium
is related to: IMEx - The International Molecular Exchange Consortium
is related to: MPIDB
is related to: TissueNet - The Database of Human Tissue Protein-Protein Interactions
is related to: InteroPorc
is related to: Interaction Reference Index
is related to: ConsensusPathDB
is related to: NIH Data Sharing Repositories
is related to: PSICQUIC Registry
is related to: Agile Protein Interactomes DataServer
has parent organization: University of California at Los Angeles; California; USA
NIGMS PMID:14681454 Free, Available for download, Freely available OMICS_01905, nif-0000-00569, r3d100010882, biotools:dip https://dip.doe-mbi.ucla.edu/dip/Main.cgi
https://bio.tools/dip
https://doi.org/10.17616/R3431F
SCR_003167 , Database of Interacting Proteins, DIP, Database of Interacting Proteins (DIP) 2026-02-14 02:00:41 153
Piano
 
Resource Report
Resource Website
100+ mentions
Piano (RRID:SCR_003200) data analysis software, software resource, data processing software, software application Software R-package for running gene set analysis using various statistical methods, from different gene level statistics and a wide range of gene-set collections. The Piano package contains functions for combining the results of multiple runs of gene set analyses. r, omics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Chalmers University of Technology; Gothenburg; Sweden
has parent organization: Bioconductor
PMID:23444143 Free, Available for download, Freely available OMICS_01558, biotools:piano https://bio.tools/piano SCR_003200 2026-02-14 02:00:42 182
Solas
 
Resource Report
Resource Website
1+ mentions
Solas (RRID:SCR_003168) sequence analysis software, data processing software, data analysis software, source code, software application, software resource Software package for the statistical language R, devoted to the analysis of next generation short read data of RNA-seq transcripts. It provides predictions of alternative exons in a single condition/cell sample, predictions of differential alternative exons between two conditions/cell samples, and quantification of alternative splice forms in a single condition/cell sample. r statistical package, rna seq, exon prediction, exon splicing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: R Project for Statistical Computing
has parent organization: Max Planck Institute for Molecular Genetics; Berlin; Germany
Free, Available for download, Freely available biotools:solas, OMICS_01339 https://bio.tools/solas SCR_003168 2026-02-14 02:00:23 8
GenePattern
 
Resource Report
Resource Website
1000+ mentions
GenePattern (RRID:SCR_003201) GenePattern data analysis software, software resource, data processing software, software application A powerful genomic analysis platform that provides access to hundreds of tools for gene expression analysis, proteomics, SNP analysis, flow cytometry, RNA-seq analysis, and common data processing tasks. A web-based interface provides easy access to these tools and allows the creation of multi-step analysis pipelines that enable reproducible in silico research. gene expression, analysis, genomic, pattern, proteomics, silico, snp, workflow, analysis pipeline, flow cytometry, rna-seq, data processing, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is affiliated with: GenePattern Notebook
is related to: TIGRESS
has parent organization: Broad Institute
NCI ;
NIGMS
PMID:16642009 Free, Freely available biotools:genepattern, OMICS_01855, nif-0000-30654 https://bio.tools/genepattern SCR_003201 2026-02-14 02:00:23 1078
PIRSF
 
Resource Report
Resource Website
10+ mentions
PIRSF (RRID:SCR_003352) PIRSF data or information resource, narrative resource, database, standard specification A SuperFamily classification system, with rules for functional site and protein name, to facilitate the sensible propagation and standardization of protein annotation and the systematic detection of annotation errors. The PIRSF concept is being used as a guiding principle to provide comprehensive and non-overlapping clustering of UniProtKB sequences into a hierarchical order to reflect their evolutionary relationships. The PIRSF classification system is based on whole proteins rather than on the component domains; therefore, it allows annotation of generic biochemical and specific biological functions, as well as classification of proteins without well-defined domains. There are different PIRSF classification levels. The primary level is the homeomorphic family, whose members are both homologous (evolved from a common ancestor) and homeomorphic (sharing full-length sequence similarity and a common domain architecture). At a lower level are the subfamilies which are clusters representing functional specialization and/or domain architecture variation within the family. Above the homeomorphic level there may be parent superfamilies that connect distantly related families and orphan proteins based on common domains. Because proteins can belong to more than one domain superfamily, the PIRSF structure is formally a network. The FTP site provides free download for PIRSF. protein annotation, classification, protein, superfamily, functional site, protein name, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: UniProtKB
has parent organization: Protein Information Resource
NHGRI U01-HG02712;
NSF DBI-0138188;
NSF ITR-0205470
PMID:19455212
PMID:14681371
Free, Freely available biotools:pirsf, nif-0000-03294, OMICS_01697 https://bio.tools/pirsf http://pir.georgetown.edu/pirsf/ SCR_003352 PIR SuperFamily, Protein Information Resource SuperFamily 2026-02-14 02:00:46 28
ALDEx2
 
Resource Report
Resource Website
500+ mentions
ALDEx2 (RRID:SCR_003364) software resource Software tool to examine compositional high-throughput sequence data with Welch's t-test. A differential relative count abundance analysis for the comparison of two conditions. For example, single-organism and meta-rna-seq high-throughput sequencing assays, or of selected and unselected values from in-vitro sequence selections. Uses a Dirichlet-multinomial model to infer abundance from counts, that has been optimized for three or more experimental replicates. Infers sampling variation and calculates the expected Benjamini-Hochberg false discovery rate given the biological and sampling variation using several parametric and non-parametric tests. Can to glm and Kruskal-Wallace tests on one-way ANOVA style designs. standalone software, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: aldex
has parent organization: Western University; Ontario; Canada
PMID:24910773 Free, Available for download, Freely available biotools:aldex2, OMICS_04634 https://bio.tools/aldex2 SCR_003364 2026-02-14 02:00:32 529
ggbio
 
Resource Report
Resource Website
10+ mentions
ggbio (RRID:SCR_003313) software resource An R package for extending the grammar of graphics for genomic data. The graphics are designed to answer common scientific questions, in particular those often asked of high throughput genomics data. All core Bioconductor data structures are supported, where appropriate. The package supports detailed views of particular genomic regions, as well as genome-wide overviews. Supported overviews include ideograms and grand linear views. High-level plots include sequence fragment length, edge-linked interval to data view, mismatch pileup, and several splicing summaries. standalone software, unix/linux, mac os x, windows, r, infrastructure, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:22937822 Free, Available for download, Freely available biotools:ggbio, OMICS_04660 http://www.tengfei.name/ggbio/
https://bio.tools/ggbio
SCR_003313 ggbio - Visualization tools for genomic data 2026-02-14 02:00:45 14
deFuse
 
Resource Report
Resource Website
50+ mentions
deFuse (RRID:SCR_003279) sequence analysis software, data processing software, data analysis software, software toolkit, software application, software resource Software package for gene fusion discovery using RNA-Seq data. It uses clusters of discordant paired end alignments to inform a split read alignment analysis for finding fusion boundaries. rna sequencing, gene fusion, paired end alignment, split read, fusion boundary, bio.tools uses: SAMTOOLS
uses: Bowtie
uses: BLAT
uses: GMAP
uses: R Project for Statistical Computing
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
British Columbia Cancer Foundation ;
Vancouver General Hospital Foundation ;
Genome Canada ;
Michael Smith Foundation for Health Research ;
Canadian Breast Cancer Foundation ;
Canadian Institutes of Health Research's Bioinformatics Training Program
PMID:21625565 Free, Available for download, Freely available biotools:defuse, OMICS_01345 https://sourceforge.net/projects/defuse/
http://compbio.bccrc.ca/software/defuse/
https://bio.tools/defuse
http://sourceforge.net/apps/mediawiki/defuse/index.php?title=Main_Page SCR_003279 2026-02-14 02:00:44 95
PrimerSeq
 
Resource Report
Resource Website
1+ mentions
PrimerSeq (RRID:SCR_003295) PrimerSeq software resource Software that designs RT-PCR primers that evaluate alternative splicing events by incorporating RNA-Seq data. It is particularly advantageous for designing a large number of primers for validating alternative splicing events found in RNA-Seq data. It incorporates RNA-Seq data in the design process to weight exons by their read counts. Essentially, the RNA-Seq data allows primers to be placed using actually expressed transcripts. This could be for a particular cell line or experimental condition, rather than using annotations that incorporate transcripts that are not expressed for the data. Alternatively, you can design primers that are always on constitutive exons. PrimerSeq does not limit the use of gene annotations and can be used for a wide array of species. primer, rna-seq, rt-pcr, windows, mac os x, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:24747190 Free, Available for download, Freely available biotools:primerseq, OMICS_02328 https://bio.tools/primerseq SCR_003295 Primer Seek in RNA-Seq 2026-02-14 02:00:25 7
MIPgen
 
Resource Report
Resource Website
10+ mentions
MIPgen (RRID:SCR_003325) software resource Software for a fast, simple way to generate designs for MIP assays targeting hundreds or thousands of genomic loci in parallel. Packaged with MIPgen are scripts that aid in visualization of MIP designs and processing of MIP sequence reads to SAM files that can then be passed through any standard variant calling pipeline. standalone software, c++, python, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Washington; Seattle; USA
PMID:24867941 Free, Available for download, Freely available OMICS_04657, biotools:mipgen https://github.com/shendurelab/MIPGEN
https://bio.tools/mipgen
SCR_003325 MIPgen - One stop MIP design and analysis 2026-02-14 02:00:46 48
Snakemake
 
Resource Report
Resource Website
100+ mentions
Snakemake (RRID:SCR_003475) Snakemake software resource A Python based language and execution environment for make-like workflows. The system supports the use of automatically inferred multiple named wildcards (or variables) in input and output filenames. python, workflow, bio.tools is used by: RiboSnake
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:22908215
DOI:10.1093/bioinformatics/bts480
Free, Available for download, Freely available OMICS_02299, biotools:snakemake https://snakemake.github.io/ SCR_003475 snakemake - A Python based language and execution environment for make-like workflows 2026-02-14 02:00:49 393
PheWAS R Package
 
Resource Report
Resource Website
1+ mentions
PheWAS R Package (RRID:SCR_003512) software resource Software package contains methods for performing Phenome-Wide Association Study. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Vanderbilt University; Tennessee; USA
PMID:20335276 Free OMICS_00242, biotools:phewas https://bio.tools/phewas SCR_003512 Phenome-Wide Association Study 2026-02-14 02:00:28 6
Cell Image Library (CIL)
 
Resource Report
Resource Website
10+ mentions
Cell Image Library (CIL) (RRID:SCR_003510) CIL data repository, storage service resource, data or information resource, service resource, image repository, database Freely accessible, public repository of vetted and annotated microscopic images, videos, and animations of cells from a variety of organisms, showcasing cell architecture, intracellular functionalities, and both normal and abnormal processes. Explore by Cell Process, Cell Component, Cell Type or Organism. The Cell includes images acquired from historical and modern collections, publications, and by recruitment. microscopic image repository, microscopic video repository, cell animation repository, bio.tools is used by: NIF Data Federation
is recommended by: National Library of Medicine
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: Cell Centered Database
is related to: Cell Centered Database
is related to: OME-TIFF Format
is related to: Integrated Manually Extracted Annotation
has parent organization: American Society for Cell Biology
has parent organization: University of California; San Diego;National Center for Microscopy and Imaging Research - NCMIR
has parent organization: University of California at San Diego; California; USA
is parent organization of: Biological Imaging Methods Ontology
NIGMS RC2 GM092708 PMID:34218671
PMID:34218673
Free, Freely available biotools:cellimagelibrary, nif-0000-37639, r3d100011601 http://www.cellimagelibrary.org/pages/about
https://bio.tools/cellimagelibrary
https://doi.org/10.17616/R3N92J
SCR_003510 Cell Image Library. CIL, Cell Image Library (CIL) 2026-02-14 02:00:34 19
Bpipe
 
Resource Report
Resource Website
10+ mentions
Bpipe (RRID:SCR_003471) Bpipe software resource Software tool for running and managing bioinformatics pipelines. It specializes in enabling users to turn existing pipelines based on shell scripts or command line tools into highly flexible, adaptable and maintainable workflows with a minimum of effort. Bpipe ensures that pipelines execute in a controlled and repeatable fashion and keeps audit trails and logs to ensure that experimental results are reproducible. Requiring only Java as a dependency, it is fully self-contained and cross-platform, making it very easy to adopt and deploy into existing environments. genetics, dna, analysis, cluster, workflow, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:22500002 Free, Available for download, Freely available biotools:bpipe, OMICS_02301 https://github.com/ssadedin/bpipe SCR_003471 bpipe - A tool for running and managing bioinformatics pipelines 2026-02-14 02:00:49 13

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