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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Scupa
 
Resource Report
Resource Website
1+ mentions
Scupa (RRID:SCR_025755) Scupa data processing software, data analysis software, source code, software application, software resource Software R package for immune cell polarization assessment of scRNA-seq data. Single-cell unified polarization assessment of immune cells using single-cell foundation model. Used for comprehensive immune cell polarization analysis. immune cell polarization analysis, immune cell polarization assessment, scRNA-seq data, Cancer Prevention and Research Institute of Texas ;
NLM R01LM012806;
NIA U01AG079847;
NIA R01CA276513
PMID:39229048 Free, Available for download, Freely available SCR_025755 Single-Cell Unified Polarization Assessment 2026-02-14 02:09:18 2
Human Microbiome Compendium
 
Resource Report
Resource Website
1+ mentions
Human Microbiome Compendium (RRID:SCR_026991) data or information resource, portal, project portal Project portal to build dataset of human microbiome. Provides dataset of human microbiome sequencing data processed and integrated via uniform pipelines. Sample metadata paired with amplicon and shotgun metagenomic datasets pulled from public databases. microbiome, compendium, dataset, public data, amplicon, shotgun, metagenomics, NLM R01LM013863 PMID:39848248 https://doi.org/10.5281/zenodo.8186993 SCR_026991 2026-02-14 02:09:13 1
T Cell ExTRECT
 
Resource Report
Resource Website
T Cell ExTRECT (RRID:SCR_027742) software resource, source code, software toolkit Software R package to calculate T cell fractions from WES data from hg19 or hg38 aligned genomes. T-cell, T cell receptor excision circle, WES data, hg19 or hg38 aligned genomes, NHLBI U54HL108460;
NCATS UL1TR000100;
NCI R21CA177519;
NCI P30CA023100;
NCI U01CA196406;
NLM T15LM011271;
NIH Office of the Director DP5OD017937;
NSF
PMID:34497419 Free, Available for download, Freely available SCR_027742 , T cell exome TREC, T cell exome T cell Receptor Excision Circle 2026-02-14 02:09:59 0
PubChem
 
Resource Report
Resource Website
10000+ mentions
PubChem (RRID:SCR_004284) data repository, storage service resource, data or information resource, service resource, database Collection of information about chemical structures and biological properties of small molecules and siRNA reagents hosted by the National Center for Biotechnology Information (NCBI). collection, information, data, chemical, structure, biological, property, small, molecule, siRNA reagent, bio.tools uses: ChEMBL
is used by: NIF Data Federation
is used by: Pathway Analysis Tool for Integration and Knowledge Acquisition
is used by: GEROprotectors
is listed by: OMICtools
is listed by: re3data.org
is listed by: NIH Data Sharing Repositories
is listed by: bio.tools
is listed by: Debian
is related to: NCBI Structure
is related to: Molecular Libraries Program
is related to: NIH Data Sharing Repositories
is related to: PubChem BioAssay
has parent organization: NCBI
is parent organization of: PubChem Substance
works with: MiMeDB
NLM PMID:21418625
PMID:21272340
PMID:20970519
PMID:20298522
PMID:19825798
Free, Freely Available biotools:pubchem, nlx_42691, nlx_29861, r3d100010538, OMICS_01587 https://bio.tools/pubchem
https://doi.org/10.17616/R3GW37
SCR_004284 2026-02-14 02:00:42 13540
OligoGenome
 
Resource Report
Resource Website
1+ mentions
OligoGenome (RRID:SCR_006025) OligoGenome data or information resource, database, resource The Stanford Human OligoGenome Project hosts a database of capture oligonucleotides for conducting high-throughput targeted resequencing of the human genome. This set of capture oligonucleotides covers over 92% of the human genome for build 37 / hg19 and over 99% of the coding regions defined by the Consensus Coding Sequence (CCDS). The capture reaction uses a highly multiplexed approach for selectively circularizing and capturing multiple genomic regions using the in-solution method developed in Natsoulis et al, PLoS One 2011. Combined pools of capture oligonucleotides selectively circularize the genomic DNA target, followed by specific PCR amplification of regions of interest using a universal primer pair common to all of the capture oligonucleotides. Unlike multiplexed PCR methods, selective genomic circularization is capable of efficiently amplifying hundreds of genomic regions simultaneously in multiplex without requiring extensive PCR optimization or producing unwanted side reaction products. Benefits of the selective genomic circularization method are the relative robustness of the technique and low costs of synthesizing standard capture oligonucleotide for selecting genomic targets. oligonucleotide, genome, probe, coding region, oligonucleotide sequence, chromosome has parent organization: Stanford University; Stanford; California NHGRI RC2 HG005570-01;
NCI R21CA12848;
NCI 5K08CA96879?6;
NIDDK DK56339;
NHGRI 2P01HG000205;
NLM T15-LM007033;
Doris Duke Clinical Foundation ;
Reddere Foundation ;
Liu Bie Ju Cha and Family Fellowship in Cancer ;
Wang Family Foundation ;
Howard Hughes Medical Foundation
PMID:22102592 nlx_151422 SCR_006025 Stanford Human Oligo Genome Project, Human OligoGenome Resource, Stanford Human Oligo Genome, Human Oligo Genome, Human OligoGenome 2026-02-14 02:01:13 2
NMR Restraints Grid
 
Resource Report
Resource Website
NMR Restraints Grid (RRID:SCR_006127) NMR Restraints Grid data or information resource, image collection, database Original NMR (nuclear magnetic resonance) data as collected for over 2500 protein and nucleic acid structures with corresponding PDB entries. In addition to the original restraints, most of the distance, dihedral angle and RDC restraint data (>85%) were parsed, and those in over 500 entries were converted and filtered. The converted and filtered data sets constitute the Database Of Converted Restraints (DOCR) and the Filtered Restraints Database (FRED) respectively as described in the references. There are 9,672,968 parsed constraints in 7159 entries. (Mar. 2013) nmr, biomolecule, structure, magnetic resonance, database of converted restraint, filtered restraints database, fred, mri, protein, nucleic acid is related to: NRG-CING
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
has parent organization: Biological Magnetic Resonance Data Bank (BMRB)
European Union FP6 contract QLG2-CT-2000-01313;
NLM LM05799
PMID:12766409
PMID:16041478
Please acknowledge the references in publications where the data from this site have been utilized. nlx_151606 SCR_006127 BMRB NMR Restraints Grid 2026-02-14 02:01:03 0
Olfactory Receptor DataBase
 
Resource Report
Resource Website
1+ mentions
Olfactory Receptor DataBase (RRID:SCR_007830) ORDB data repository, storage service resource, data analysis service, analysis service resource, data or information resource, production service resource, service resource, database Database of vertebrate olfactory receptors genes and proteins. It supports sequencing and analysis of these receptors by providing a comprehensive archive with search tools for this expanding family. The database also incorporates a broad range of chemosensory genes and proteins, including the taste papilla receptors (TPRs), vomeronasal organ receptors (VNRs), insect olfaction receptors (IORs), Caenorhabditis elegans chemosensory receptors (CeCRs), and fungal pheromone receptors (FPRs). ORDB currently houses chemosensory receptors for more than 50 organisms. ORDB contains public and private sections which provide tools for investigators to analyze the functions of these very large gene families of G protein-coupled receptors. It also provides links to a local cluster of databases of related information in SenseLab, and to other relevant databases worldwide. The database aims to house all of the known olfactory receptor and chemoreceptor sequences in both nucleotide and amino acid form and serves four main purposes: * It is a repository of olfactory receptor sequences. * It provides tools for sequence analysis. * It supports similarity searches (screens) which reduces duplicate work. * It provides links to other types of receptor information, e.g. 3D models. The database is accessible to two classes of users: * General public www users have full access to all the public sequences, models and resources in the database. * Source laboratories are the laboratories that clone olfactory receptors and submit sequences in the private or public database. They can search any sequence they deposited to the database against any private or public sequence in the database. This user level is suited for laboratories that are actively cloning olfactory receptors. fungal, pheromone receptor, gene, chemosensory, chemosensory receptor, g protein-coupled receptor, olfaction receptor, protein, receptor, taste papilla receptor, vomeronasal organ receptor, olfactory receptor, nucleotide, amino acid, chemoreceptor sequence, olfactory receptor sequence, chemoreceptor, sequence is used by: NIF Data Federation
is listed by: 3DVC
is related to: Odor Molecules DataBase
is related to: Integrated Manually Extracted Annotation
has parent organization: Yale School of Medicine; Connecticut; USA
Aging Human Brain Project ;
NIMH ;
NIA ;
NICD ;
NINDS ;
Multidisciplinary University Research Initiative ;
National Aeronautics and Space Administration ;
NIDCD RO1 DC 009977;
NIDCD P01 DC 04732;
NLM G08 LM05583
PMID:11752336
PMID:9847223
PMID:9218144
Public, Private, Acknowledgement requested, The community can contribute to this resource nif-0000-03213 SCR_007830 Olfactory Receptors Database 2026-02-14 02:01:26 4
REBASE
 
Resource Report
Resource Website
100+ mentions
REBASE (RRID:SCR_007886) REBASE data or information resource, database Database of information about restriction enzymes and related proteins containing published and unpublished references, recognition and cleavage sites, isoschizomers, commercial availability, methylation sensitivity, crystal, genome, and sequence data. DNA methyltransferases, homing endonucleases, nicking enzymes, specificity subunits and control proteins are also included. Several tools are available including REBsites, BLAST against REBASE, NEBcutter and REBpredictor. Putative DNA methyltransferases and restriction enzymes, as predicted from analysis of genomic sequences, are also listed. REBASE is updated daily and is constantly expanding. Users may submit new enzyme and/or sequence information, recommend references, or send them corrections to existing data. The contents of REBASE may be browsed from the web and selected compilations can be downloaded by ftp (ftp.neb.com). Additionally, monthly updates can be requested via email., endonuclease, enzyme, genome, archaeal, bacterial, cleavage, crystal, dna, individual protein family databases, isochizomer, methylation, methyltransferase, modification, protein, recognition, restriction, restriction enzyme, sensitivity, sequence, site, methylase, cleavage site, restriction-modification, blast, FASEB list has parent organization: New England Biolabs
works with: Webcutter
New England Biolabs Inc ;
NLM LM04971
PMID:19846593
PMID:17202163
r3d100012171, nif-0000-03391 http://rebase.neb.com
https://doi.org/10.17616/R3J930
http://www.neb.com/rebase SCR_007886 The Restriction Enzyme Database, Restriction Enzyme Database 2026-02-14 02:01:35 246
Array Information Library Universal Navigator
 
Resource Report
Resource Website
1+ mentions
Array Information Library Universal Navigator (RRID:SCR_006967) AILUN data analysis service, analysis service resource, resource, data or information resource, production service resource, service resource, database Re-annotated gene expression / proteomics data from GEO by relating all probe IDs to Entrez Gene IDs once every three months, enabling you to find data from GEO, and compare them from different platforms and species. Platform Annotations adds the latest annotations to any uploaded probe / gene ID list file. Platform Comparison compares any two platforms to find corresponding probes mapping to the same gene. Cross-species mapping maps platform annotations to other species. Gene Search finds deposited platforms and samples in GEO that contain a list of genes. GPL ID Search finds the GPL ID (GEO platform ID) for your array. You can also download the latest annotations files for all arrays and their comprehensive universal gene identifier table, which relates all types of gene / protein / clone identifiers to Entrez Gene IDs for all species. Note: The database was last updated on 4/30/2011. They have successfully mapped 54932732 individual probes from 385099 GEO samples measuring 3519 GEO platforms across 217 species. gene expression, gene, array, clone, probe, protein, proteomic, annotation, analytical service, probe id, comparison, microarray, probe sequence, gene identifier, annotation file, web service is related to: Gene Expression Omnibus
is related to: Entrez Gene
has parent organization: Stanford University School of Medicine; California; USA
Lucile Packard Foundation for Childrens Health ;
Howard Hughes Medical Institute ;
Pharmaceutical Research and Manufacturers of America Foundation ;
NLM K22 LM008261;
NIDDK R01GM079719
PMID:17971777 nif-0000-33004 SCR_006967 2026-02-14 02:01:16 5
Virtual Human Embryo
 
Resource Report
Resource Website
10+ mentions
Virtual Human Embryo (RRID:SCR_006921) VHE data or information resource, image collection, database A digital image database of serially sectioned human embryos from the Carnegie Collection originally developed as a collaboration between embryologist Dr. Raymond Gasser at Louisiana State University Health Science Center (LSUHSC) and the Human Developmental Anatomy Center (HDAC) in Washington D.C. The aim of the project is to increase understanding of human embryology and to encourage study of human embryonic development by providing students and researchers with reliable resources for human embryo morphology. The VHE project has several components: * DREM: The Digitally Reproduced Embryonic Morphology (DREM) project, with funding from NICHD, project has produced 27 image databases of labeled serial sections from representative human embryos at each of the 23 Carnegie stages. These databases, together with animations and reconstructions of the embryos are available on DVD and CD. * HEIRLOOM: The HEIRLOOM Collection (Human Embryo Imaging and Reconstruction, Library Of Online Media) was funded by the National Library of Medicine to provide greater access to the DREM databases. NLM provided funding to set up this website and to produce additional 3D-reconstructions and animations that are included on the DREM disks. Original website, http://virtualhumanembryo.lsuhsc.edu/HEIRLOOM/heirloom.htm * EHD: Starting in 2011, The Endowment for Human Development (EHD) will also host the VHE databases. They have made the project accessible to everyone and include a comprehensive cataloging of all the terms used to label the embryos. Their website enables users to browse through the complete VHE atlas of human embryology, http://www.ehd.org/virtual-human-embryo/ embryo, embryonic human, development, embryology, morphology, carnegie stage, 3d-reconstruction has parent organization: Louisiana State University Health Sciences Center New Orleans; Louisiana; USA NICHD R01 HD37811;
NLM R01 LM007591
nlx_152029 SCR_006921 Virtual Human Embryo Project 2026-02-14 02:01:25 23
FLASH
 
Resource Report
Resource Website
1000+ mentions
FLASH (RRID:SCR_005531) FLASh sequence analysis software, data processing software, data analysis software, software application, software resource Open source software tool to merge paired-end reads from next-generation sequencing experiments. Designed to merge pairs of reads when original DNA fragments are shorter than twice length of reads. Can improve genome assemblies and transcriptome assembly by merging RNA-seq data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: shovill
is related to: CLIP-Explorer
has parent organization: Johns Hopkins University; Maryland; USA
NLM R01 LM006845;
NIGMS R01 GM083873;
NHGRI R01 HG006677
PMID:21903629 Free, Available for download, Freely available biotools:flash, OMICS_01047 https://sourceforge.net/projects/flashpage/files/
https://bio.tools/flash
https://sources.debian.org/src/flash/
SCR_005531 Fast Length Adjustment of SHort reads, Fast Length Adjustment of Short reads 2026-02-14 02:00:55 2175
GeneTests
 
Resource Report
Resource Website
10+ mentions
GeneTests (RRID:SCR_010725) GeneTests portal, analysis service resource, material analysis service, data or information resource, production service resource, biomaterial analysis service, service resource, narrative resource, training material, topical portal, database The GeneTests Web site, a publicly funded medical genetics information resource developed for physicians, other healthcare providers, and researchers, is available at no cost to all interested persons. By providing current, authoritative information on genetic testing and its use in diagnosis, management, and genetic counseling, GeneTests promotes the appropriate use of genetic services in patient care and personal decision making. At This Site: * GeneReviews: Expert-authored peer-reviewed disease descriptions * Laboratory Directory: International directory of genetic testing laboratories * Clinic Directory: International directory of genetics and prenatal diagnosis clinics * Educational Materials: Illustrated glossary, information on genetic services, PowerPoint presentations, annotated Internet resources We comply with the HONcode standard for trustworthy health information. has parent organization: University of Washington; Seattle; USA
has parent organization: NCBI
NCI ;
NHGRI 1 P41 LM/HG 06029;
NLM 1 P41 LM/HG 06029;
NLM contract N01-LM-4-3505;
NLM 5 P41 LM07242;
NLM 2 P41 LM 06001;
DOE DE-FG03-02ER63301/A00
nlx_94696 SCR_010725 GeneTests: Clinical Genetic Information Resource 2026-02-14 02:02:04 12
MUMmer
 
Resource Report
Resource Website
100+ mentions
MUMmer (RRID:SCR_018171) data processing software, alignment software, software application, software resource, image analysis software Software package as system for rapidly aligning entire genomes. Alignment tool for DNA and protein sequences. Can align incomplete genomes. Align, genome, DNA, protein, sequence, , bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
is related to: MUMmerGPU
NLM R01 LM06845;
NSF IIS 9902923;
NIAID N01 AI15447
PMID:14759262 Free, Available for download, Freely available OMICS_14554, biotools:mummer https://github.com/mummer4/mummer
https://bio.tools/mummer
https://sources.debian.org/src/mummer/
SCR_018171 MUMmer4, MUMmer 3.0 2026-02-14 02:03:34 480
fMRIPrep
 
Resource Report
Resource Website
1000+ mentions
fMRIPrep (RRID:SCR_016216) image processing software, software resource, data processing software, software application Software tool as robust preprocessing pipeline for functional MRI.Used for preprocessing of diverse fMRI data. Processing data, fmri, neuroimaging, coregistration, normalization, unwarping, noise, component, extraction, segmentation, skullstripping uses: Nipype
has parent organization: Poldracklab Portal
works with: NiPoppy
Laura and John Arnold Fundation ;
NIDCR UL1 DE019580;
NIMH RL1 MH083268;
NIMH RL1 MH083269;
NIMH RL1 DA024853;
NIMH RL1 MH083270;
NIMH PL1 MH083271;
NLM RL1 LM009833;
NINDS PL1 NS062410
PMID:30532080
PMID:32514178
Free, Available for download, Freely available https://zenodo.org/record/1219187#.WuDlO4jwZPY SCR_016216 fMRIPrep, FMRI PREP 2026-02-14 02:03:10 1190
lilikoi
 
Resource Report
Resource Website
1+ mentions
lilikoi (RRID:SCR_016361) data processing software, data analysis software, software toolkit, software application, software resource Software tool as an R package for personalized pathway-based classification modeling using metabolomics data. Provides personalized pathway deregulation measurements (PDS scores) and offers a standardized classification model for biomarker prediction. personalized, medicine, metabolomics, data, classification, clustering, biomarker, prediction, algorithm, calculating, microarray, enrichment is listed by: OMICtools
is related to: University of Hawaii; Hawaii; USA
NIEHS K01 ES025434;
NIGMS GM103457;
NLM R01 LM012373;
NICHD R01 HD084633
DOI:https://doi.org/10.1101/283408 Free, Available for download, Freely available https://omictools.com/lilikoi-tool SCR_016361 2026-02-14 02:03:03 3
LRPath
 
Resource Report
Resource Website
1+ mentions
LRPath (RRID:SCR_018572) web service, analysis service resource, production service resource, service resource, data access protocol, software resource Web tool to perform gene set enrichment testing. Used to test for predefined biologically relevant gene sets that contain more significant genes from experimental dataset than expected by chance. Logistic regression approach for identifying enriched biological groups in gene expression data. Gene, map, gene set, gene set testing, identifying enriched biologically group, gene expression data, gene expression, data, bio.tools is listed by: bio.tools
is listed by: Debian
NIEHS P30 ES06096;
NIEHS U01 ES015675;
NHGRI R01 HG003749;
NLM R01 LM008106;
NIDA U54 DA021519
PMID:19038984 Free, Freely available biotools:lrpath https://bio.tools/lrpath SCR_018572 2026-02-14 02:03:39 4
Limitation-Recognizer
 
Resource Report
Resource Website
Limitation-Recognizer (RRID:SCR_018747) data analysis software, software resource, data processing software, software application Software tool to recognize self acknowledged limitation sentences in biomedical articles. Automatic recognition of self acknowledged limitations in clinical research literature to support efforts in improving research transparency. ASWG, automatic recognition, self acknowledged limitation, clinical research literature, research transparency, limitation sentence recognition uses: Stanford CoreNLP
has parent organization: University of Illinois at Urbana-Champaign; Illinois; USA
NLM PMID:29718377 Free, Freely available SCR_018748 SCR_018747 limitationrecognizer, limitation recognizer, limitation-recognizer 2026-02-14 02:03:39 0
ANTIGENpro
 
Resource Report
Resource Website
100+ mentions
ANTIGENpro (RRID:SCR_018779) data access protocol, software resource, web service, service resource Web tool as sequence-based, alignment-free and pathogen-independent predictor of protein antigenicity.Predicts likelihood that protein is protective antigen. Integrated in SCRATCH suite of predictors. Protein antigenicity, sequence based predictior, alignment free predictor, pathogen independent predictor, protein antigenicity predictor, SCRATCH suite, predictor has parent organization: University of California at Irvine; California; USA NLM LM 07443;
NSF EIA 0321390;
NSF 0513376;
Microsoft Faculty Research Award
PMID:20934990 Free, Freely available SCR_018779 2026-02-14 02:03:40 247
Heuristic Identification of Biological Architectures for simulating Complex Hierarchical Interactions
 
Resource Report
Resource Website
Heuristic Identification of Biological Architectures for simulating Complex Hierarchical Interactions (RRID:SCR_017140) HIBACHI, hibachi software resource, simulation software, software application Software tool that creates data sets with particular characteristics. Method and open source software for simulating complex biological and biomedical data to aid in comparing and evaluating machine learning methods. data, simulation, dataset, compare, machine, evaluate, learning, method NLM LM012601;
NIAID AI116794;
NIDDK DK112217
PMID:29218887 Free, Available for download, Freely available SCR_017140 Heuristic Identification of Biological Architectures for simulating Complex Hierarchical Interactions 2026-02-14 02:03:15 0
U-Compare
 
Resource Report
Resource Website
1+ mentions
U-Compare (RRID:SCR_004911) U-Compare data processing software, text-mining software, workflow software, service resource, software application, software resource An integrated text mining / natural language processing system based on the Unstructured Information Management Architecture (UIMA) Framework. It allows interoperability of text mining tools and allows the creation of text mining workflows, comparison and visualization of tools. U-Compare can be launched straight from the web or downloaded. As the name implies comparison of components and workflows is a central feature of the system. U-Compare allows sets of components to be run in parallel on the same inputs and then automatically generates statistics for all possible combinations of these components. Once a workflow has been created in U-Compare it can be exported and shared with other users or used with other UIMA compatible tools and so in addition to comparison, U-Compare also functions as a general purpose workflow creation tool. It contains a repository of 50+ biomedical text mining components. These components are included in the U-Compare single-click-to-launch package, ready to use by just drag-and-drop. You can also use this repository independent from the U-Compare system. Link with Taverna It has a link with Taverna for scientific workflows, http://bioinformatics.oxfordjournals.org/content/26/19/2486.abstract, where you can use U-Compare and its workflow from within the Taverna workflow. There are two ways, the U-Compare Taverna plugin and the U-Compare command line mode as a Taverna activity. We have recently integrated it with Peter Murray-Rust''''s OSCAR for Chemistry (see http://www.nactem.ac.uk/cheta/) Web Demo: http://www.nactem.ac.uk/software/cheta/ statistics, text mining, natural language processing, interoperability, comparison, workflow, computational linguistics is listed by: FORCE11
is related to: Taverna
is related to: Chemistry Using Text Annotations
is related to: Oscar3
has parent organization: University of Tokyo; Tokyo; Japan
has parent organization: National Centre for Text Mining
has parent organization: University of Colorado Denver; Colorado; USA
NIGMS R01 GM083649-04;
NLM R01 LM008111-07;
NIGMS R01GM083649;
NLM R01LM008111;
NLM R01LM009254
PMID:19414535 nlx_87780 SCR_004911 2026-02-14 02:01:02 5

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