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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Boston Children's Hospital Center of Excellence in Molecular Hematology Zebrafish Core
 
Resource Report
Resource Website
Boston Children's Hospital Center of Excellence in Molecular Hematology Zebrafish Core (RRID:SCR_015355) core facility, access service resource, service resource, resource Zebrafish core facility which generates and maintains transgenic and mutant fish lines for hematology research. It also provides expertise and training in model production, study design, and fish production for research. zebrafish model, transgenic fish, mutant fish line is listed by: NIDDK Information Network (dkNET)
has parent organization: Boston Children's Hospital Center of Excellence in Molecular Hematology
is organization facet of: Boston Children's Hospital Center of Excellence in Molecular Hematology
NIDDK U54DK110805 Available to the research community SCR_015355 2026-02-14 02:08:28 0
Boston Children's Hospital Center of Excellence in Molecular Hematology Stem Cell Engineering and Analysis Core
 
Resource Report
Resource Website
Boston Children's Hospital Center of Excellence in Molecular Hematology Stem Cell Engineering and Analysis Core (RRID:SCR_015352) core facility, access service resource, service resource, resource Core facility for basic and translational stem cell research. The core's areas of expertise include human pluripotent stem cell biology, cGMP cell manufacturing, reprogramming, genome editing, genotyping, laboratory automation, chemical screening, and imaging/image analysis. basic stem cell research, translational stem cell research, stem cell core facility is listed by: NIDDK Information Network (dkNET)
has parent organization: Boston Children's Hospital Center of Excellence in Molecular Hematology
is organization facet of: Boston Children's Hospital Center of Excellence in Molecular Hematology
NIDDK U54DK110805 Available to the research community, Fee for service SCR_015352 2026-02-14 02:08:03 0
Pittsburgh Center for Kidney Research Model Organisms
 
Resource Report
Resource Website
Pittsburgh Center for Kidney Research Model Organisms (RRID:SCR_015288) core facility, access service resource, service resource, resource Core that uses the yeast S. cerevisiae and the zebrafish D. rerio to dissect fundamental aspects of kidney development and protein structure and function. renal disease, protein disorders, kidney disease, zebrafish is listed by: NIDDK Information Network (dkNET)
has parent organization: Pittsburgh Center for Kidney Research
is organization facet of: Pittsburgh Center for Kidney Research
NIDDK P30DK079307;
University of Pittsburgh School of Medicine; Pennsylvania; USA ;
Icahn School of Medicine at Mount Sinai; New York; USA
Available to the research community SCR_015288 2026-02-14 02:08:02 0
University of Alabama at Birmingham Nutrition and Obesity Research Center Animal Models Core
 
Resource Report
Resource Website
University of Alabama at Birmingham Nutrition and Obesity Research Center Animal Models Core (RRID:SCR_015466) core facility, access service resource, service resource, resource Core that provides specialized expertise in the use of animal models and instrumentation to facilitate animal research related to nutrition and obesity. obesity animal model, nutrition animal model, animal model service is listed by: NIDDK Information Network (dkNET)
has parent organization: University of Alabama at Birmingham; Alabama; USA
has parent organization: University of Alabama at Birmingham Nutrition and Obesity Research Center
is organization facet of: University of Alabama at Birmingham Nutrition and Obesity Research Center
Obesity NIDDK P30DK056336 Available to the research community, Fee for service SCR_015466 2026-02-14 02:07:59 0
APPRIS
 
Resource Report
Resource Website
50+ mentions
APPRIS (RRID:SCR_012019) APPRIS data or information resource, database A database that houses annotations of human splice isoforms. It adds reliable protein structural and functional data and information from cross-species conservation. A visual representation of the annotations for each gene allows users to easily identify functional changes brought about by splicing events. In addition to collecting, integrating and analyzing reliable predictions of the effect of splicing events, it also selects a single reference sequence for each gene, termed the principal isoform, based on the annotations of structure, function and conservation for each transcript. isoform, function, annotation, splice, reference sequence, structure, conservation, transcript, FASEB list is listed by: OMICtools
has parent organization: Spanish National Cancer Research Center
PMID:23161672 Free OMICS_01881 SCR_012019 APPRIS - A system for annotating alternative splice isoforms 2026-02-14 02:06:21 85
Zebrafish Gene Collection
 
Resource Report
Resource Website
1+ mentions
Zebrafish Gene Collection (RRID:SCR_007054) ZGC biomaterial supply resource, material resource Part of zebrafish genome project. ZGC project to produce cDNA libraries, clones and sequences to provide complete set of full-length (open reading frame) sequences and cDNA clones of expressed genes for zebrafish. All ZGC sequences are deposited in GenBank and clones can be purchased from distributors of IMAGE consortium. With conclusion of ZGC project in September 2008, GenBank records of ZGC sequences will be frozen, without further updates. Since definition of what constitutes full-length coding region for some of genes and transcripts for which we have ZGC clones will likely change in future, users planning to order ZGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as UCSC Genome browser, NCBI's Map Viewer, and Entrez Gene, to view relevant regions of genome (browsers) or gene-related information (Entrez Gene). cdna library, clone, sequence, full-length open reading frame, cdna clone, frozen, fish, gene, genetic, genome, genomic is listed by: One Mind Biospecimen Bank Listing
is related to: One Mind Biospecimen Bank Listing
is related to: NIDDK Information Network (dkNET)
is related to: Mammalian Gene Collection
is related to: GenBank
is related to: ATCC
has parent organization: National Cancer Institute
NIH Blueprint for Neuroscience Research Free, Freely available nif-0000-00567 https://genecollections.nci.nih.gov/ZGC/ SCR_007054 Zebrafish Gene Collection 2026-02-14 02:07:03 1
ZMP
 
Resource Report
Resource Website
10+ mentions
ZMP (RRID:SCR_006161) ZMP biomaterial supply resource, material resource Create knockout alleles in protein coding genes in the zebrafish genome, using a combination of whole exome enrichment and Illumina next generation sequencing, with the aim to cover them all. Each allele created is analyzed for morphological differences and published on the ZMP site. Transcript counting is performed on alleles with a morphological phenotype. Alleles generated are archived and can be requested from this site through the Zebrafish International Resource Center (ZIRC). You may register to receive updates on genes of interest, or browse a complete list, or search by Ensembl ID, gene name or human and mouse orthologue. phenotype, genome, gene, disease model, allele, orthologue, mutant, chromosome, human orthologue, mouse orthologue, mutation, knockout, human, mouse, transcript is listed by: One Mind Biospecimen Bank Listing
is related to: Zebrafish International Resource Center
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust Sanger Institute; Hinxton; United Kingdom ;
NIH ;
ZF-HEALTH
Free and open nlx_151662 SCR_006161 Zebrafish Mutation Project (ZMP), Zebrafish Mutation Project, ZMP - Zebrafish Mutation Project 2026-02-14 02:07:02 25
EID: Exon-Intron Database
 
Resource Report
Resource Website
10+ mentions
EID: Exon-Intron Database (RRID:SCR_002469) EID data or information resource, data set Data sets of protein-coding intron-containing genes that contain gene information from humans, mice, rats, and other eukaryotes, as well as genes from species whose genomes have not been completely sequenced. This is a comprehensive and convenient dataset of sequences for computational biologists who study exon-intron gene structures and pre-mRNA splicing. The database is derived from GenBank release 112, and it contains protein-coding genes that harbor introns, along with extensive descriptions of each gene and its DNA and protein sequences, as well as splice motif information. They have created subdatabases of genes whose intron positions have been experimentally determined. The collection also contains data on untranslated regions of gene sequences and intron-less genes. For species with entirely sequenced genomes, species-specific databases have been generated. A novel Mammalian Orthologous Intron Database (MOID) has been introduced which includes the full set of introns that come from orthologous genes that have the same positions relative to the reading frames. eukaryote genome, exon, exon-intro, gene structure, genome splicing, intron, ortholog, fasta, gene, protein-coding gene, splice, motif, gene prediction, structure, coding region is listed by: OMICtools
has parent organization: University of Toledo; Ohio; USA
PMID:16772261
PMID:10592221
Free, Available for download, Freely available OMICS_01886, nif-0000-02793 http://www.utoledo.edu/med/depts/bioinfo/database.html http://www.meduohio.edu/bioinfo/eid/, http://mcb.harvard.edu/gilbert/EID SCR_002469 The Exon-Intron Database, Exon-Intron Database 2026-02-14 02:07:47 11
Zebrafish Information Server
 
Resource Report
Resource Website
Zebrafish Information Server (RRID:SCR_002237) ZIS data or information resource, organism-related portal, portal, topical portal A portal to different zebrafish resources such as jobs, book, journals, database, meetings, and K-12 programs. Most information leads to ZFIN: The Zebrafish Model Organism Database. database, job, k12 program, journal, monitor, zebrafish, book, meeting, method has parent organization: University of South Carolina; South Carolina; USA THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-21003 SCR_002237 2026-02-14 02:00:20 0
Ensembl
 
Resource Report
Resource Website
10000+ mentions
Ensembl (RRID:SCR_002344) data or information resource, database Collection of genome databases for vertebrates and other eukaryotic species with DNA and protein sequence search capabilities. Used to automatically annotate genome, integrate this annotation with other available biological data and make data publicly available via web. Ensembl tools include BLAST, BLAT, BioMart and the Variant Effect Predictor (VEP) for all supported species. collection, genome, dataset, database, vertebrate, eukaryotic, DNA, protein, sequence, search, automaticly, annotate, data, bio.tools, FASEB list is used by: NIF Data Federation
is used by: Animal QTLdb
is used by: ChannelPedia
is used by: Blueprint Epigenome
is used by: HmtPhenome
lists: Ensembl Covid-19
is listed by: OMICtools
is listed by: Biositemaps
is listed by: re3data.org
is listed by: LabWorm
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Ensembl Genomes
is related to: GermOnline
is related to: CandiSNPer
is related to: Human Splicing Finder
is related to: NGS-SNP
is related to: Sanger Mouse Resources Portal
is related to: DECIPHER
is related to: Ensembl Genomes
is related to: PeptideAtlas
is related to: AnimalTFDB
is related to: Bgee: dataBase for Gene Expression Evolution
is related to: FlyMine
is related to: Rat Gene Symbol Tracker
is related to: UniParc at the EBI
is related to: go-db-perl
is related to: UniParc
is related to: g:Profiler
is related to: RIKEN integrated database of mammals
is related to: VBASE2
is related to: p300db
is related to: ShinyGO
has parent organization: European Bioinformatics Institute
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
is parent organization of: Ensembl Metazoa
is parent organization of: Ensembl Variation
is parent organization of: Pre Ensembl
is parent organization of: Variant Effect Predictor
is parent organization of: Ensembl Bacteria
is parent organization of: Ensembl Plants
is parent organization of: Ensembl Fungi
is parent organization of: Ensembl Protists
is parent organization of: Ensembl Genome Browser
works with: Genotate
works with: CellPhoneDB
works with: Open Regulatory Annotation Database
works with: Database of genes related to Repeat Expansion Diseases
works with: TarBase
Wellcome Trust ;
EMBL ;
European Union ;
FP7 ;
FP6 ;
MRC ;
NHGRI ;
BBSRC
PMID:24316576
PMID:23203987
nif-0000-21145, OMICS_01647, biotools:ensembl, r3d100010228 https://bio.tools/ensembl
https://sources.debian.org/src/ensembl/
https://doi.org/10.17616/R39K5B
SCR_002344 ENSEMBL 2026-02-14 02:00:23 11652
MONARCH Initiative
 
Resource Report
Resource Website
10+ mentions
MONARCH Initiative (RRID:SCR_000824) Monarch data or information resource, database Repository of information about model organisms, in vitro models, genes, pathways, gene expression, protein and genetic interactions, orthology, disease, phenotypes, publications, and authors, and ability to navigate multi-scale spatial and temporal phenotypes across in vivo and in vitro model systems in context of genetic and genomic data, using semantics and statistics. Discovery system provides basic and clinical science researchers, informaticists, and medical professionals with integrated interface and set of discovery tools to reveal genetic basis of disease, facilitate hypothesis generation, and identify novel candidate drug targets. Database that indexes authoritative information on experimental models of disease from MGI, RGD and ZFIN. disease, animal model, phenotype, model organism, in vitro model, gene, pathway, gene expression, protein interaction, genetic interaction, orthology, disease, publication, author, genetic, genomic, model system, genotype, drug, in vivo model uses: Animal QTLdb
uses: Ensembl Variation
uses: Human Phenotype Ontology
is used by: NIF Data Federation
is related to: Mouse Genome Informatics (MGI)
is related to: Rat Genome Database (RGD)
is related to: Zebrafish Information Network (ZFIN)
is related to: openSNP
is related to: Ancora
is related to: PhenoGen Informatics
is related to: Lifespan Observations Database
has parent organization: Oregon Health and Science University; Oregon; USA
is parent organization of: monarch-ontologies
NIH Office of the Director R24 OD011883 PMID:26269093 Free, Freely available r3d100011594, nlx_152525, SCR_001373, nlx_152748 https://orip.nih.gov/comparative-medicine/programs/genetic-biological-and-information-resources
https://doi.org/10.17616/R31M09
SCR_000824 MONARCH Integrated Disease Model, MONARCH Integrated Disease Models View, MONARCH Disease Models View, The MONARCH Initiative 2026-02-14 01:59:54 12
Zebrafish Anatomical Ontology
 
Resource Report
Resource Website
1+ mentions
Zebrafish Anatomical Ontology (RRID:SCR_005887) ZFA data or information resource, ontology, controlled vocabulary A structured controlled vocabulary of the anatomy and development of the Zebrafish (Danio rerio). It includes a list of structures, organized hierarchically into an ontology, with descriptions of each structure. The current version is being written by a consortium of researchers, each serving as an expert for a particular set of anatomical structures. Additional anatomical information derived from the current literature is provided by the ZFIN curation group. Development of a complete and uniform anatomical ontology for the zebrafish is vital to the success of zebrafish science. The anatomical ontology is necessary for: * Effective data dissemination and informatics. * A reference framework. * Interoperability. anatomy, structure, anatomical structure, obo is used by: Teleost Anatomy Ontology
is recommended by: Zebrafish Brain Atlas
is listed by: BioPortal
is related to: OBO
is related to: Bgee: dataBase for Gene Expression Evolution
has parent organization: Zebrafish Information Network (ZFIN)
nlx_149454 SCR_005887 Zebrafish Anatomy and Development Ontology, ZFIN - Zebrafish Anatomical Ontology 2026-02-14 02:01:01 4
phenomeNET
 
Resource Report
Resource Website
10+ mentions
phenomeNET (RRID:SCR_006165) PhenomeNet data analysis service, analysis service resource, data or information resource, production service resource, source code, service resource, software resource, database PhenomeNet is a cross-species phenotype similarity network. It contains the experimentally observed phenotypes of multiple species as well as the phenotypes of human diseases. PhenomeNet provides a measure of phenotypic similarity between the phenotypes it contains. The latest release (from 22 June 2012) contains 124,730 complex phenotype nodes taken from the yeast, fish, worm, fly, rat, slime mold and mouse model organism databases as well as human disease phenotypes from OMIM and OrphaNet. The network is a complete graph in which edge weights represent the degree of phenotypic similarity. Phenotypic similarity can be used to identify and prioritize candidate disease genes, find genes participating in the same pathway and orthologous genes between species. To compute phenotypic similarity between two sets of phenotypes, we use a weighted Jaccard index. First, phenotype ontologies are used to infer all the implications of a phenotype observation using several phenotype ontologies. As a second step, the information content of each phenotype is computed and used as a weight in the Jaccard index. Phenotypic similarity is useful in several ways. Phenotypic similarity between a phenotype resulting from a genetic mutation and a disease can be used to suggest candidate genes for a disease. Phenotypic similarity can also identify genes in a same pathway or orthologous genes. PhenomeNet uses the axioms in multiple species-dependent phenotype ontologies to infer equivalent and related phenotypes across species. For this purpose, phenotype ontologies and phenotype annotations are integrated in a single ontology, and automated reasoning is used to infer equivalences. Specifically, for every phenotype, PhenomeNet infers the related mammalian phenotype and uses the Mammalian Phenotype Ontology for computing phenotypic similarity. Tools: * PhenomeBLAST - A tool for cross-species alignments of phenotypes * PhenomeDrug - method for drug-repurposing phenotype, disease, gene, genotype, allele, model organism, human disease, candidate disease gene, pathway, orthologous gene, ortholog, ontology, semantic similarity, mutant phenotype, disease pathway, alignment, pharmacogenomics, drug is related to: OMIM
is related to: Orphanet
is related to: PharmGKB
is related to: MPO
has parent organization: University of Cambridge; Cambridge; United Kingdom
European Union 7th FPRICORDO project 248502;
NHGRI R01 HG004838-02;
BBSRC BBG0043581
PMID:21737429 The source code and all data are freely available on http://phenomeblast.googlecode.com nlx_151667 SCR_006165 PhenomeNet - Cross Species Phenotype Network 2026-02-14 02:01:05 13
Zebrafish Brain Atlas
 
Resource Report
Resource Website
1+ mentions
Zebrafish Brain Atlas (RRID:SCR_000606) Zebrafish Brain Atlas data repository, storage service resource, data or information resource, atlas, service resource, image repository Collates and curates neuroanatomical data and information generated both in-house and by community to communicate current state of knowledge about neuroanatomical structures in developing zebrafish. Most of data come from high resolution confocal imaging of intact brains in which neuroanatomical structures are labelled by combinations of transgenes and antibodies. Community repository for image based data related to neuroanatomy of zebrafish. brain, neuroanatomy, developing, transgene, antibody, confocal, section, reconstruction, high-resolution, developmental stage, embryo, brain structure, confocal imaging, comparative anatomy, transgenic, 3d spatial image, video, embryonic zebrafish, development, annotation, narrative resource, training material, cell repository recommends: Zebrafish Anatomical Ontology
is listed by: One Mind Biospecimen Bank Listing
has parent organization: University College London; London; United Kingdom
European Union ;
Wellcome Trust ;
BBSRC
Public, (Transgenic lines), Freely available for academic use, Creative Commons license, (pending verification), The community can contribute to this resource nlx_149455 http://zebrafishucl.org/ http://www.ucl.ac.uk/zebrafish-group/zebrafishbrain/index.php SCR_000606 , zebrafishbrain.org, Zebrafish Brain Atlas 2026-02-14 01:59:49 3
NeuroMorpho.Org
 
Resource Report
Resource Website
50+ mentions
NeuroMorpho.Org (RRID:SCR_002145) data repository, storage service resource, data or information resource, service resource, database Centrally curated inventory of digitally reconstructed neurons associated with peer-reviewed publications that contains some of the most complete axonal arborizations digitally available in the community. Each neuron is represented by a unique identifier, general information (metadata), the original and standardized ASCII files of the digital morphological reconstruction, and a set of morphometric features. It contains contributions from over 100 laboratories worldwide and is continuously updated as new morphological reconstructions are collected, published, and shared. Users may browse by species, brain region, cell type or lab name. Users can also download morphological reconstructions for research and analysis. Deposition and distribution of reconstruction files ultimately prevents data loss. Centralized curation and annotation aims at minimizing the effort required by data owners while ensuring a unified format. It also provides a one-stop entry point for all available reconstructions, thus maximizing data visibility and impact. neuron, morphological reconstruction, morphometry, axonal arborization, digital neuronal reconstruction, neuronal reconstruction, neuronal morphology, data sharing, annotation, brain region, neocortex, digital reconstruction, neurogenetics, neurochemistry, neuroscience, neurology, FASEB list is used by: NIF Data Federation
is used by: BICCN
is recommended by: National Library of Medicine
is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: re3data.org
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: DONE: Detection of Outlier NEurons
is related to: NIF Literature
is related to: Computational Neurobiology and Imaging Center
is related to: Integrated Manually Extracted Annotation
is related to: xyz2swc
is related to: Allen Institute for Brain Science
has parent organization: George Mason University; Virginia; USA
is parent organization of: NeuroMorpho.Org species ontology
is parent organization of: NeuroMorpho.Org species ontology old
NINDS R01 NS39600;
MURI ONR N000141010198
PMID:17728438
PMID:16552417
PMID:18949582
Free, Available for download, Freely available nif-0000-00006, r3d100010107 http://www.nitrc.org/projects/neuromorpho_org
http://neuromorpho.org/
https://doi.org/10.17616/R3WW2K
SCR_002145 Neuro Morpho, NeuroMorpho.org, NeuroMorpho 2026-02-14 02:00:22 96
GeneInfoViz
 
Resource Report
Resource Website
GeneInfoViz (RRID:SCR_005680) GeneInfoViz data analysis service, analysis service resource, data or information resource, production service resource, service resource, database GeneInfoViz is a web based tool for batch retrieval of gene function information, visualization of GO structure and construction of gene relation networks. It takes a input list of genes in the form of LocusLink ID, UniGeneID, gene symbol, or accession number and returns their functional genomic information. Based on the GO annotations of the given genes, GeneInfoViz allows users to visualize these genes in the DAG structure of GO, and construct a gene relation network at a selected level of the DAG. Platform: Online tool gene network, gene ontology, visualization, gene, ontology or annotation browser is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of Tennessee Health Science Center; Tennessee; USA
PMID:15724283 Free for academic use nlx_149121 SCR_005680 GeneInfoViz: Constructing and Visualizing Gene Relation Networks 2026-02-14 02:01:10 0
Edwards Lab
 
Resource Report
Resource Website
1+ mentions
Edwards Lab (RRID:SCR_008860) Edwards Lab portal, laboratory portal, data or information resource, organization portal, topical portal The Edwards lab conducts research in various aspects of computational biology and bioinformatics, particularly proteomics and mass spectrometry informatics and DNA and protein based signatures for pathogen detection. Some tools provided by Edwards Lab are the PepArML Meta-Search Engine, PeptideMapper Web-Service, Peptide Sequence Databases, Rapid Microorganism Identification Database (RMIDb), and GlycoPeptideSearch. Our primary area of research is the analysis of mass spectrometry experiments for proteomics. Proteomics, the qualitative and quantitative analysis of the expressed proteins of a cell, makes it possible to detect and compare the protein abundance profiles of different samples. Proteins observed to be under or over expressed in disease samples can lead to diagnostic markers or drug targets. The observation of mutated or alternatively spliced protein isoforms may provide domain experts with clues to the mechanisms by which a disease operates. The detection of proteins by mass spectrometry can even signal the presence of airborne microorganisms, such as anthrax, in the detect-to-protect time-frame. Recent research has focused on the discovery of novel peptides in proteomics datasets, improving the sensitivity and specificity of peptide identification using spectral matching with hidden Markov models, and unsupervised machine-learning based peptide identification result combining. Outside of proteomics, we work on computational tools for the design of highly specific oligonucleotides useful for pathogen signatures and PCR assay design. Recent research has focused on precomputing all human oligos of length 20 that are unique up to 4 string edits; and all bacterial 20-mer oligos that are species specific up to 4 string edits. peptide, proteomics, computational biology, bioinformatics, mass spectrometry, informatics, oligonucleotide, peptide sequence has parent organization: Georgetown University; Washington D.C.; USA
is parent organization of: PeptideMapper
is parent organization of: Peptide Sequence Database
is parent organization of: GlycoPeptideSearch
nlx_149188 SCR_008860 Georgetown - Edwards Lab, Georgetown University - Edwards Lab, GU - Edwards Lab 2026-02-14 02:01:46 1
EGAN: Exploratory Gene Association Networks
 
Resource Report
Resource Website
1+ mentions
EGAN: Exploratory Gene Association Networks (RRID:SCR_008856) EGAN data analysis software, software resource, data processing software, software application Exploratory Gene Association Networks (EGAN) is a software tool that allows a bench biologist to visualize and interpret the results of high-throughput exploratory assays in an interactive hypergraph of genes, relationships (protein-protein interactions, literature co-occurrence, etc.) and meta-data (annotation, signaling pathways, etc.). EGAN provides comprehensive, automated calculation of meta-data coincidence (over-representation, enrichment) for user- and assay-defined gene lists, and provides direct links to web resources and literature (NCBI Entrez Gene, PubMed, KEGG, Gene Ontology, iHOP, Google, etc.). EGAN functions as a module for exploratory investigation of analysis results from multiple high-throughput assay technologies, including but not limited to: * Transcriptomics via expression microarrays or RNA-Seq * Genomics via SNP GWAS or array CGH * Proteomics via MS/MS peptide identifications * Epigenomics via DNA methylation, ChIP-on-Chip or ChIP-Seq * In-silico analysis of sequences or literature EGAN has been built using Cytoscape libraries for graph visualization and layout, and is comparable to DAVID, GSEA, Ingenuity IPA and Ariadne Pathway Studio. There are pre-collated EGAN networks available for human (Homo sapiens), mouse (Mus musculus), rat (Rattus norvegicus), chicken (Gallus gallus), zebrafish (Danio rerio), fruit fly (Drosophila melanogaster), nematode (Caenorhabditis elegans), mouse-ear cress (Arabidopsis thaliana), rice (Oryza sativa) and brewer's yeast (Saccharomyces cerevisiae). There is now an EGAN module available for GenePattern (human-only). Platform: Windows compatible, Mac OS X compatible, Linux compatible gene, gene association, network, protein-protein interaction, pathway, interaction, annotation, signaling pathway, enrichment, cytoscape, visualization is listed by: 3DVC
is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: Cytoscape
has parent organization: UCSF Helen Diller Family Comprehensive Cancer Center Biostatistics Core
NCI P30 CA92103 PMID:19933825 Free for academic use nlx_149222 SCR_008856 Exploratory Gene Association Networks, Exploratory Gene Association Networks (EGAN) 2026-02-14 02:01:48 8
Comparative Toxicogenomics Database (CTD)
 
Resource Report
Resource Website
1000+ mentions
Comparative Toxicogenomics Database (CTD) (RRID:SCR_006530) CTD data analysis service, analysis service resource, data or information resource, production service resource, service resource, database A public database that enhances understanding of the effects of environmental chemicals on human health. Integrated GO data and a GO browser add functionality to CTD by allowing users to understand biological functions, processes and cellular locations that are the targets of chemical exposures. CTD includes curated data describing cross-species chemical–gene/protein interactions, chemical–disease and gene–disease associations to illuminate molecular mechanisms underlying variable susceptibility and environmentally influenced diseases. These data will also provide insights into complex chemical–gene and protein interaction networks. environment, chemical, disease, gene, pathway, protein, interaction, animal model, ontology, annotation, toxin, ontology or annotation browser, FASEB list is used by: DisGeNET
is used by: NIF Data Federation
is listed by: 3DVC
is listed by: Gene Ontology Tools
is related to: PharmGKB Ontology
is related to: Gene Ontology
is related to: BioRAT
is related to: Integrated Gene-Disease Interaction
is related to: OMICtools
is related to: Integrated Manually Extracted Annotation
has parent organization: Mount Desert Island Biological Laboratory
has parent organization: North Carolina State University; North Carolina; USA
is parent organization of: Interaction Ontology
Pfizer ;
American Chemistry Council ;
NIEHS ES014065;
NIEHS R01 ES019604;
NCRR P20 RR016463;
NIEHS U24 ES033155
PMID:16902965
PMID:16675512
PMID:14735110
PMID:12760826
Free, Freely available OMICS_01578, nif-0000-02683, r3d100011530 http://ctd.mdibl.org
https://doi.org/10.17616/R3KS7N
SCR_006530 CTD - Comparative Toxicogenomics Database 2026-02-14 02:01:19 1188
WebGestalt: WEB-based GEne SeT AnaLysis Toolkit
 
Resource Report
Resource Website
1000+ mentions
WebGestalt: WEB-based GEne SeT AnaLysis Toolkit (RRID:SCR_006786) WebGestalt data access protocol, software resource, web service, web application Web based gene set analysis toolkit designed for functional genomic, proteomic, and large-scale genetic studies from which large number of gene lists (e.g. differentially expressed gene sets, co-expressed gene sets etc) are continuously generated. WebGestalt incorporates information from different public resources and provides a way for biologists to make sense out of gene lists. This version of WebGestalt supports eight organisms, including human, mouse, rat, worm, fly, yeast, dog, and zebrafish. proteomic, gene expression, genome wide association study, statistical analysis, functional genomics, protein protein interaction, pathway, regulatory module, analysis toolkit, web application is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
is related to: Entrez Gene
is related to: KEGG
is related to: Pathway Commons
is related to: WikiPathways
is related to: PheWAS Catalog
is related to: webgestaltr
has parent organization: Vanderbilt University; Tennessee; USA
NIAAA U01 AA016662;
NIAAA U01 AA013512;
NIDA P01 DA015027;
NIMH P50 MH078028;
NIMH P50 MH096972;
NCI U24 CA159988;
NIGMS R01 GM088822
PMID:24233776
PMID:15980575
PMID:14975175
Free, Freely available OMICS_02222, nif-0000-30622 http://bioinfo.vanderbilt.edu/webgestalt/ SCR_006786 GOTM, Gene Ontology Tree Machine, WebGestalt2, WEB-based GEne SeT AnaLysis Toolkit, WebGestalt 2026-02-14 02:01:23 2760

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  1. Neuroscience Information Framework Resources

    Welcome to the NIF Resources search. From here you can search through a compilation of resources used by NIF and see how data is organized within our community.

  2. Navigation

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  3. Logging in and Registering

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  4. Searching

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    1. Use quotes around phrases you want to match exactly
    2. You can manually AND and OR terms to change how we search between words
    3. You can add "-" to terms to make sure no results return with that term in them (ex. Cerebellum -CA1)
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    5. Using autocomplete specifies which branch of our semantics you with to search and can help refine your search
  5. Collections

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  7. Further Questions

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