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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MORGAN
 
Resource Report
Resource Website
100+ mentions
MORGAN (RRID:SCR_006906) MORGAN software application, software resource Software programs for segregation and linkage analysis, using a variety of Markov chain Monte Carlo (MCMC) methods. Includes MCMC methods for multilocus gene identity by descent (including homozygosity mapping) and Monte Carlo Lod scores. Also, other programs for EM analysis of quantitative traits. gene, genetic, genomic, c, unix, compaq-alpha, solaris, linux, linkage disequilibrium, gl_lods, ibd_haplo, identity by descent, segregation, linkage analysis, markov chain monte carlo is listed by: OMICtools
is listed by: Genetic Analysis Software
has parent organization: University of Washington; Seattle; USA
NIGMS GM-46255 PMID:22298700 nlx_154201, OMICS_00205 SCR_006906 MOnte caRlo Genetic ANalysis PANGAEA 2026-02-15 09:19:24 305
PERFect
 
Resource Report
Resource Website
PERFect (RRID:SCR_024682) software application, data processing software, software resource Software R package as filtering test for microbiome data. Permutation filtering approach to address two unsolved problems in microbiome data processing: (i) define and quantify loss due to filtering by implementing thresholds and (ii) introduce and evaluate a permutation test for filtering loss to provide a measure of excessive filtering. filtering test, microbiome data, microbiome data processing, NSF ;
NIGMS 1U54GM104944
PMID:29917060 Free, Available for download, Freely available SCR_024682 Permutation Filtering Package in R 2026-02-15 09:22:46 0
WebProtege
 
Resource Report
Resource Website
1+ mentions
WebProtege (RRID:SCR_024627) web application, software resource Web based platform for editing biomedical ontologies. Web application for editing OWL 2 ontologies. Open source, lightweight, web based ontology editor implemented in Java and JavaScript using OWL API and Google Web Toolkit. For users who do not wish to host their ontologies on Stanford servers, WebProtégé is available as Web app that can be run locally using Servlet container such as Tomcat. editing biomedical ontologies, editing OWL 2 ontologies, ontology editor, OBO ontologies, has parent organization: Stanford University; Stanford; California
has parent organization: Stanford Center for Biomedical Informatics Research
NIGMS GM103316 PMID:24771560 Free, Freely available https://protegewiki.stanford.edu/wiki/WebProtege SCR_024627 WebProtégé 2026-02-15 09:23:34 2
Drug Design Data Resource
 
Resource Report
Resource Website
1+ mentions
Drug Design Data Resource (RRID:SCR_000497) D3R data or information resource, database, portal Project portal's database of protein-ligand data sets provided by pharmaceutical partners that provide atomic details of drug mechanisms that will be used to improve computer-aided drug-design methods and thus accelerate drug discovery. The project aims to help companies release the high-quality data they have generated, which has incredible value to researchers working to improve methods of computer-aided drug discovery. Everyone stands to benefit from the ability to develop new medications more quickly and inexpensively. What computational chemists globally are trying to do is to make faster, more accurate, more predictive programs to speed up the process. Part of their mission is to engage the community in these challenges to test newly developed predictive algorithms. computer-aided drug design, drug design, pharmaceutical, small molecule, ligand-protein interaction, protein, ligand, drug development, drug, binding, data set, affinity, computation, medicine, compound, structure uses: Binding MOAD
uses: Protein Data Bank Bind Database
is used by: NIF Data Federation
is listed by: DataCite
has parent organization: University of California at San Diego; California; USA
has parent organization: University of California; California; USA
NIGMS 1U01GM111528 nlx_158375 https://api.datacite.org/dois?prefix=10.15782 SCR_000497 Drug Design Data (D3R) Resource 2026-02-15 09:17:56 3
ShapeWorks
 
Resource Report
Resource Website
1+ mentions
ShapeWorks (RRID:SCR_000424) ShapeWorks software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE.Documented on September 2, 2022. Software that is an open-source distribution of a new method for constructing compact statistical point-based models of ensembles of similar shapes that does not rely on any specific surface parameterization. The method requires very little preprocessing or parameter tuning, and is applicable to a wide range of shape analysis problems, including nonmanifold surfaces and objects of arbitrary topology. The proposed correspondence point optimization uses an entropy-based minimization that balances the simplicity of the model (compactness) with the accuracy of the surface representations. The ShapeWorks software includes tools for preprocessing data, computing point-based shape models, and visualizing the results. c++, console (text based), linux, macos, microsoft, magnetic resonance, posix/unix-like, rendering, shape analysis, surface rendering, visualization, win32 (ms windows), windows, workflow is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Utah; Utah; USA
NCRR 5P41RR012553-15;
NIGMS 8 P41 GM103545-15
THIS RESOURCE IS NO LONGER IN SERVICE nlx_155961 http://www.nitrc.org/projects/shapeworks SCR_000424 2026-02-15 09:17:55 1
SpiecEasi
 
Resource Report
Resource Website
10+ mentions
SpiecEasi (RRID:SCR_022712) SpiecEasi software application, data processing software, data analysis software, software resource Software R package for microbiome network analysis. Used for inference of microbial ecological networks from amplicon sequencing datasets. Combines data transformations developed for compositional data analysis with graphical model inference framework that assumes underlying ecological association network is sparse. microbiome network analysis, amplicon sequencing datasets, microbial ecological networks inference NIAID AI007180;
NIDDK DK103358;
NIGMS GM63270;
Simons Foundation
PMID:25950956 Free, Available for download, Freely available SCR_022712 SParse InversE Covariance Estimation for Ecological Association Inference 2026-02-15 09:22:18 15
Megadepth
 
Resource Report
Resource Website
1+ mentions
Megadepth (RRID:SCR_022779) software application, data processing software, data analysis software, software resource Software tool for quantifying alignments and coverage for BigWig and BAM/CRAM input files.Quantifies number of RNA-seq reads assigned to gene in BAM file, successor of bamcounts. quantifying alignments, BigWig and BAM/CRAM input files, RNA-seq reads assigned to gene in BAM file quantification, NIGMS R01GM118568;
NIGMS R01GM121459;
UK Medical Research Council
PMID:33693500 Free, Available for download, Freely available https://bioconductor.org/packages/megadepth SCR_022779 2026-02-15 09:22:52 2
SViCT
 
Resource Report
Resource Website
1+ mentions
SViCT (RRID:SCR_023656) software application, data processing software, data analysis software, software resource Software tool for detecting structural variations from cell free DNA containing low dilutions of circulating tumor DNA. detecting structural variations, cell free DNA, cfDNA, circulating tumor DNA low dilutions, ctDNA Natural Sciences and Engineering Research Council Discovery Grant ;
Terry Fox Research Institute New Frontiers Program Project Grant ;
Natural Sciences and Engineering Research Council Discovery Frontiers Program ;
National Science Foundation ;
NIGMS GM108348;
Indiana University Grant Challenges Program ;
Precision Health Initiative
PMID:30759232 Free, Available for download, Freely available SCR_023656 Structural Variant detection in Circulating Tumor DNA 2026-02-15 09:23:22 1
GenePattern
 
Resource Report
Resource Website
1000+ mentions
GenePattern (RRID:SCR_003201) GenePattern software application, data processing software, data analysis software, software resource A powerful genomic analysis platform that provides access to hundreds of tools for gene expression analysis, proteomics, SNP analysis, flow cytometry, RNA-seq analysis, and common data processing tasks. A web-based interface provides easy access to these tools and allows the creation of multi-step analysis pipelines that enable reproducible in silico research. gene expression, analysis, genomic, pattern, proteomics, silico, snp, workflow, analysis pipeline, flow cytometry, rna-seq, data processing, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is affiliated with: GenePattern Notebook
is related to: TIGRESS
has parent organization: Broad Institute
NCI ;
NIGMS
PMID:16642009 Free, Freely available biotools:genepattern, OMICS_01855, nif-0000-30654 https://bio.tools/genepattern SCR_003201 2026-02-15 09:18:28 1078
Northwestern University Schizophrenia Data and Software Tool (NUSDAST)
 
Resource Report
Resource Website
Northwestern University Schizophrenia Data and Software Tool (NUSDAST) (RRID:SCR_014153) NUSDAT image collection, data or information resource, database A repository of schizophrenia neuroimaging data collected from over 450 individuals with schizophrenia, healthy controls and their respective siblings, most with 2-year longitudinal follow-up. The data include neuroimaging data, cognitive data, clinical data, and genetic data. database, neuroimaging, clinical, cognitive, genetic, schizophrenia, longitudinal uses: CAWorks
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Northwestern University; Illinois; USA
Schizophrenia NIMH 1R01 MH084803;
NIMH 1U01 MH097435;
NIMH P50 MH071616;
NIMH R01 MH056584;
NCRR P41 RR15241;
NIGMS U24 GM104203;
NIH Bio-Informatics Research Network Coordinating Center
Available to the research community SCR_014153 Northwestern University Schizophrenia Data and Software Tool 2026-02-15 09:20:49 0
MolProbity
 
Resource Report
Resource Website
5000+ mentions
MolProbity (RRID:SCR_014226) web application, software resource A structure-validation web application which provides an expert-system consultation about the accuracy of a macromolecular structure model, diagnosing local problems and enabling their correction. MolProbity works best as an active validation tool (used as soon as a model is available and during each rebuild/refine loop) and when used for protein and RNA crystal structures, but it may also work well for DNA, ligands and NMR ensembles. It produces coordinates, graphics, and numerical evaluations that integrate with either manual or automated use in systems such as PHENIX, KiNG, or Coot. web application, consultation, macromolecular structure, structure validation, macromolecular crystallography is listed by: SoftCite
is related to: Phenix
is related to: Coot
has parent organization: Duke University; North Carolina; USA
Howard Hughes Medical Institute Predoctoral Fellowship ;
NIGMS GM-15000;
NIGMS GM-61302
DOI:10.1107/S0907444909042073 Acknowledgement requested, Requires Java and Javascript https://www.phenix-online.org/documentation/reference/molprobity_tool.html SCR_014226 2026-02-15 09:20:53 6313
I-TASSER
 
Resource Report
Resource Website
1000+ mentions
I-TASSER (RRID:SCR_014627) software application, data processing software, data analysis software, software resource Web server as integrated platform for automated protein structure and function prediction. Used for protein 3D structure prediction. Resource for automated protein structure prediction and structure-based function annotation. Automated prediction, protein structure prediction, protein function prediction, protein 3D structure, amino acid sequence, alignment, simulation, 3D atomic model, protein, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: University of Michigan; Ann Arbor; USA
has parent organization: University of Kansas; Kansas; USA
NIGMS GM083107;
NIGMS GM084222
DOI:10.1186/1471-2105-9-40
DOI:10.1093/nar/gkv342
PMID:20360767
PMID:18215316
Free, Available for download, Freely available biotools:i-tasser, SCR_018803 https://bio.tools/i-tasser SCR_014627 Iterative Threading Assembly Refinement, Iterative Threading ASSEmbly Refinement 2026-02-15 09:21:06 3702
Track-A-Worm
 
Resource Report
Resource Website
1+ mentions
Track-A-Worm (RRID:SCR_018299) software application, data processing software, data analysis software, software resource Open source system for quantitative assessment of C. Elegans locomotory and bending behavior. Used for quantitative behavioral analyses to understand circuit and gene bases of behavior. Constantly records and analyzes position and body shape of freely moving worm at high magnification. Quantitative assessment, C.Elegans locomotory, bending behavior, behavioral analysis, gene, moving worm position, body shape, automated recording is related to: University of Connecticut; Connecticut; USA NIGMS R01 GM083049;
NIMH R01 MH085927
PMID:23922769 Free, Available for download, Freely available SCR_018299 Tracker-A-Worm version 1.0, Tracker-A-Worm version 2.0 2026-02-15 09:22:12 3
BioSimulations
 
Resource Report
Resource Website
BioSimulations (RRID:SCR_018733) web application, software resource Web tool for sharing and re-using biomodels, simulations, and visualizations of simulations results. Supports variety of modeling frameworks including kinetic, constraint based, and logical modeling, model formats including BNGL, CellML, SBML, and simulation tools including COPASI, libRoadRunner/tellurium, NFSim, VCell. Sharing, reusing, biomodel, simulation, visualization, simulation result, modeling framework support, simulation tool support, model format support, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
has parent organization: University of Connecticut; Connecticut; USA
NIBIB P41 EB023912;
NSF ;
NIGMS
Restricted biotools:biosimulations https://bio.tools/biosimulations SCR_018733 2026-02-15 09:22:23 0
TimeZone
 
Resource Report
Resource Website
1+ mentions
TimeZone (RRID:SCR_018564) software application, data processing software, data analysis software, software resource Software package to detect footprints of positive selection for functionally adaptive point mutations in microbial genomes. Detect footprint, positive selection, functionally adaptive, point mutation, microbial genome NIGMS R01 GM084318;
NIAID RC4 AI092828
PMID:23471110 Free, Available for download, Freely available SCR_018564 2026-02-15 09:22:22 1
MotionCor2
 
Resource Report
Resource Website
100+ mentions
MotionCor2 (RRID:SCR_016499) software application, data processing software, data analysis software, software resource Software tool for anisotropic correction of beam-induced motion for improved cryo-electron microscopy. Used to describe the sample motion as a local deformation that varies smoothly throughout the exposure. A program running on Linux. anisotropic, correction, beam, induced, motion, cryo, electron, microscopy, exposure, data has parent organization: University of California at San Francisco; California; USA NIH R01 GM031627;
NIGMS P01 GM111126
PMID:28250466 Restricted http://msg.ucsf.edu/em/software/motioncor2.html SCR_016499 MotionCor 2026-02-15 09:21:41 172
Phenograph
 
Resource Report
Resource Website
100+ mentions
Phenograph (RRID:SCR_016919) PhenoGraph software application, data processing software, data analysis software, software resource Software tool as clustering method designed for high dimensional single cell data. Algorithmically defines phenotypes in high dimensional single cell data. Used for large scale analysis of single cell heterogeneity. high, dimention, single, cell, data, phenotype, analysis, heterogeneity uses: Python Programming Language
is related to: Rphenograph
NIGMS R00 GM104148;
NICHD DP1 HD084071;
NCI R01 CA164729;
NCI U54 CA121852;
NCI R01 CA130826;
NCI U54 CA143907;
US Department of Health and Human Services HHSN272200700038C;
NIH N01 HV00242;
NCI P01 CA034233;
NIAID U19 AI057229;
NCI U54 CA149145;
US FDA HHSF223201210194C;
US DOD W81XWH1210591;
Entertainment Industry Foundation ;
Rachford and Carlota Harris Endowed Professorship ;
CIRM DR1 01477;
CIRM RB201592;
Stand Up To Cancer Phillip A. Sharp Award SU2CAACRPS04;
Packard Fellowship for Science and Engineering ;
NIH Office of the Director DP2 OD002414
PMID:26095251 Free, Available for download, Freely available https://github.com/JinmiaoChenLab/Rphenograph https://github.com/jacoblevine/PhenoGraph SCR_016919 2026-02-15 09:21:56 213
BinPacker
 
Resource Report
Resource Website
10+ mentions
BinPacker (RRID:SCR_017038) software application, data processing software, data analysis software, software resource Software tool as de novo trascriptome assembler for RNA-Seq data. Used to assemble full length transcripts by remodeling problem as tracking set of trajectories of items over splicing graph. Input RNA-Seq reads in fasta or fastq format, and ouput all assembled candidate transcripts in fasta format. Operating system Unix/Linux. de novo, transcriptome, assembler, RNAseq, data, full, length, transcript, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China ;
NSF 1553680;
NCRR P20 RR01 6460;
NIGMS P20 GM103429
PMID:26894997 Free, Available for download, Freely available OMICS_11199, biotools:binpacker http://sourceforge.net/projects/transcriptomeassembly/files/BinPacker_1.0.tar.gz/download
http://sourceforge.net/projects/transcriptomeassembly/files/BinPacker_binary.tar.gz/download
https://bio.tools/binpacker
SCR_017038 2026-02-15 09:21:54 10
UltraScan
 
Resource Report
Resource Website
10+ mentions
UltraScan (RRID:SCR_018126) software application, data processing software, data analysis software, software resource Software package for hydrodynamic data from analytical ultracentrifugation experiments. Features integrated data editing and analysis environment with portable graphical user interface. Provides resolution for sedimentation velocity experiments using high-performance computing modules for 2-dimensional spectrum analysis, genetic algorithm, and for Monte Carlo analysis. Hydrodynamic data, analytical ultracentrifugation experiment, data editing, analysis, sedimentation velocity experiment, spectrum analysis, genetic algorithm, Monte Carlo analysis NSF DBI 9724273;
NSF DBI 9974819;
NSF ANI 228927;
NSF TG-MCB 060019T;
NSF TG-MCB 070038;
NSF TG-MCB 070039;
NSF TG-MCB 070040;
NSF OCI 1032742;
NSF ACI 1339649;
NCRR RR022200;
NCRR RR 022200 03S1;
NIGMS GM120600;
San Antonio Life Science Institute ;
Howard Hughes Medical Institute ;
Robert J. Kleberg Jr. and Helen C. Kleberg Foundation
Free, Available for download, Freely available SCR_018126 2026-02-15 09:21:32 20
nbdocker
 
Resource Report
Resource Website
nbdocker (RRID:SCR_017159) software application, software resource Software tool as Jupyter Notebook extension for Docker. Each Docker container encapsulates its individual computing environment to allow different programming languages and computing environments to be included in one single notebook, provides user to document code as well as computing environment. Jupyter, notebook, extension, docker, container, code, computing, environment, data is related to: University of Washington; Seattle; USA NHLBI U54 HL127624;
NIGMS R01 GM126019;
Institute of Technology at University of Washington Tacoma
DOI:10.1101/309567 Free, Available for download, Freely available https://hub.docker.com/r/biodepot/nbdocker/ SCR_017159 2026-02-15 09:21:57 0

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