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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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  • RRID:SCR_017610

    This resource has 1+ mentions.

http://bloodexposome.org

Collection of chemical compounds and associated information that were automatically extracted by text mining content of PubMed and PubChem databases. Unifies chemical lists from metabolomics, systems biology, environmental epidemiology, occupational expossure, toxiology and nutrition fields.

Proper citation: Blood Exposome Database (RRID:SCR_017610) Copy   


http://www.demogr.mpg.de/databases/ktdb/

A database that includes data on death counts and population counts classified by sex, age, year of birth, and calendar year for more than 30 countries. This database was established for estimating the death rates at the highest ages (above age 80). The core set of data in the database was assembled, tested for quality, and converted into cohort mortality histories by V��in�� Kannisto, the former United Nations advisor on demographic and social statistics. Comparable materials on England and Wales, was made available by A. Roger Thatcher, the former Director of the Office of Population Censuses and Surveys and Registrar-General of England and Wales (Kannisto, 1994). The Kannisto-Thatcher database was computerized under the supervision of James W. Vaupel at the Aging Research Unit of the Centre for Health and Social Policy at Odense University Medical School in 1993. Currently, the database is maintained by the Max Planck Institute for Demographic Research, Germany.

Proper citation: Kannisto-Thatcher Database on Old Age Mortality (RRID:SCR_008936) Copy   


http://www.icpsr.umich.edu/icpsrweb/NACDA/Pledge/all.jsp

A data set of cross-nationally comparable microdata samples for 15 Economic Commission for Europe (ECE) countries (Bulgaria, Canada, Czech Republic, Estonia, Finland, Hungary, Italy, Latvia, Lithuania, Romania, Russia, Switzerland, Turkey, UK, USA) based on the 1990 national population and housing censuses in countries of Europe and North America to study the social and economic conditions of older persons. These samples have been designed to allow research on a wide range of issues related to aging, as well as on other social phenomena. A common set of nomenclatures and classifications, derived on the basis of a study of census data comparability in Europe and North America, was adopted as a standard for recoding. This series was formerly called Dynamics of Population Aging in ECE Countries. The recommendations regarding the design and size of the samples drawn from the 1990 round of censuses envisaged: (1) drawing individual-based samples of about one million persons; (2) progressive oversampling with age in order to ensure sufficient representation of various categories of older people; and (3) retaining information on all persons co-residing in the sampled individual''''s dwelling unit. Estonia, Latvia and Lithuania provided the entire population over age 50, while Finland sampled it with progressive over-sampling. Canada, Italy, Russia, Turkey, UK, and the US provided samples that had not been drawn specially for this project, and cover the entire population without over-sampling. Given its wide user base, the US 1990 PUMS was not recoded. Instead, PAU offers mapping modules, which recode the PUMS variables into the project''''s classifications, nomenclatures, and coding schemes. Because of the high sampling density, these data cover various small groups of older people; contain as much geographic detail as possible under each country''''s confidentiality requirements; include more extensive information on housing conditions than many other data sources; and provide information for a number of countries whose data were not accessible until recently. Data Availability: Eight of the fifteen participating countries have signed the standard data release agreement making their data available through NACDA/ICPSR (see links below). Hungary and Switzerland require a clearance to be obtained from their national statistical offices for the use of microdata, however the documents signed between the PAU and these countries include clauses stipulating that, in general, all scholars interested in social research will be granted access. Russia requested that certain provisions for archiving the microdata samples be removed from its data release arrangement. The PAU has an agreement with several British scholars to facilitate access to the 1991 UK data through collaborative arrangements. Statistics Canada and the Italian Institute of statistics (ISTAT) provide access to data from Canada and Italy, respectively. * Dates of Study: 1989-1992 * Study Features: International, Minority Oversamples * Sample Size: Approx. 1 million/country Links: * Bulgaria (1992), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/02200 * Czech Republic (1991), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06857 * Estonia (1989), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06780 * Finland (1990), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06797 * Romania (1992), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06900 * Latvia (1989), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/02572 * Lithuania (1989), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/03952 * Turkey (1990), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/03292 * U.S. (1990), http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06219

Proper citation: Census Microdata Samples Project (RRID:SCR_008902) Copy   


  • RRID:SCR_002370

    This resource has 100+ mentions.

http://www.mortality.org/

A database providing detailed mortality and population data to those interested in the history of human longevity. For each country, the database includes calculated death rates and life tables by age, time, and sex, along with all of the raw data (vital statistics, census counts, population estimates) used in computing these quantities. Data are presented in a variety of formats with regard to age groups and time periods. The main goal of the database is to document the longevity revolution of the modern era and to facilitate research into its causes and consequences. New data series is continually added to this collection. However, the database is limited by design to populations where death registration and census data are virtually complete, since this type of information is required for the uniform method used to reconstruct historical data series. As a result, the countries and areas included are relatively wealthy and for the most part highly industrialized. The database replaces an earlier NIA-funded project, known as the Berkeley Mortality Database. * Dates of Study: 1751-present * Study Features: Longitudinal, International * Sample Size: 37 countries or areas

Proper citation: Human Mortality Database (RRID:SCR_002370) Copy   


http://lehd.did.census.gov/led/

A dataset that combines federal and state administrative data on employers and employees with core Census Bureau censuses and surveys, while protecting the confidentiality of people and firms that provide the data. This data infrastructure facilitates longitudinal research applications in both the household / individual and firm / establishment dimensions. The specific research is targeted at filling an important gap in the available data on older workers by providing information on the demand side of the labor market. These datasets comprise Title 13 protected data from the Current Population Surveys, Surveys of Income and Program Participation, Surveys of Program Dynamics, American Community Surveys, the Business Register, and Economic Censuses and Surveys. With few exceptions, states have partnered with the Census Bureau to share data. As of December 2008, Connecticut, Massachusetts, New Hampshire and Puerto Rico have not signed a partnership agreement, while a partnership with the Virgin Islands is pending. LEHD's second method of developing employer-employee data relations through the use of federal tax data has been completed. LEHD has produced summary tables on accessions, separation, job creation, destruction and earnings by age and sex of worker by industry and geographic area. The data files consist of longitudinal datasets on all firms in each participating state (quarterly data, 1991- 2003), with information on age, sex, turnover, and skill level of the workforce as well as standard information on employment, payroll, sales and location. These data can be accessed for all available states from the Project Website. Data Availability: Research conducted on the LEHD data and other products developed under this proposal at the Census Bureau takes place under a set of rules and limitations that are considerably more constraining than those prevailing in typical research environments. If state data are requested, the successful peer-reviewed proposals must also be approved by the participating state. If federal tax data are requested, the successful peer-reviewed proposals must also be approved by the Internal Revenue Service. Researchers using the LEHD data will be required to obtain Special Sworn Status from the Census Bureau and be subject to the same legal penalties as regular Census Bureau employees for disclosure of confidential information. Basic instructions on how to download the data files and restrictions can be found on the Project Website. * Dates of Study: 1991-present * Study Features: Longitudinal * Sample Size: 48 States or U.S. territories

Proper citation: Longitudinal Employer-Household Dynamics (RRID:SCR_000817) Copy   


http://crag.uab.edu/crag/active.asp

Data set from a randomized controlled trial of cognitive interventions designed to maintain functional independence in elders by improving basic mental abilities. Several features made ACTIVE unique in the field of cognitive interventions: (a) use of a multi-site, randomized, controlled, single-blind design; (b) intervention on a large, diverse sample; (c) use of common multi-site intervention protocols, (d) primary outcomes focused on long-term, cognitively demanding functioning as measured by performance-based tests of daily activities; and (e) an intent-to-treat analytical approach. The clinical trial ended with the second annual post-test in January 2002. A third annual post-test was completed in December 2003. The area population and recruitment strategies at the six field sites provided a study sample varying in racial, ethnic, gender, socioeconomic, and cognitive characteristics. At baseline, data were collected by telephone for eligibility screening, followed by three in-person assessment sessions, including two individual sessions and one group session, and a self-administered questionnaire. At post-tests, data were collected in-person in one individual session and one group session as well as by self-administered questionnaire. There were four major categories of measures: proximal outcomes (measures of cognitive abilities that were direct targets of training), primary outcomes (measures of everyday functioning, both self-report and performance), secondary outcomes (measures of health, mobility, quality of life, and service utilization), and covariates (chronic disease, physical characteristics, depressive symptoms, cognitive impairment, psychosocial variables, and demographics). Phase I of ACTIVE was a randomized controlled, single-blind trial utilizing a four-group design, including three treatment arms and a no-contact control group. Each treatment arm consisted of a 10-session intervention for one of three cognitive abilities memory, reasoning, and speed of processing. Testers were blind to participant treatment assignment. The design allowed for testing of both social contact effects (via the contact control group) and retest effects (via the no-contact control group) on outcomes. Booster training was provided in each treatment arm to a 60% random subsample prior to first annual post-test. Phase II of ACTIVE started in July, 2003 as a follow-up study focused on measuring the long-term impact of training effects on cognitive function and cognitively demanding everyday activities. The follow-up consisted of one assessment to include the Phase I post-test battery. This was completed in late 2004.

Proper citation: Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) (RRID:SCR_000813) Copy   


http://www.oasis-brains.org/

Project aimed at making neuroimaging data sets of brain freely available to scientific community. By compiling and freely distributing neuroimaging data sets, future discoveries in basic and clinical neuroscience are facilitated.

Proper citation: Open Access Series of Imaging Studies (RRID:SCR_007385) Copy   


  • RRID:SCR_007286

    This resource has 1+ mentions.

http://senselab.med.yale.edu/odordb

OdorDb is a database of odorant molecules, which can be searched in a few different ways. One can see odorant molecules in the OdorDB, and the olfactory receptors in ORDB that they experimentally shown to bind. You can search for odorant molecules based on their attributes or identities: Molecular Formula, Chemical Abstracts Service (CAS) Number and Chemical Class. Functional studies of olfactory receptors involve their interactions with odor molecules. OdorDB contains a list of odors that have been identified as binding to olfactory receptors.

Proper citation: Odor Molecules DataBase (RRID:SCR_007286) Copy   


  • RRID:SCR_002380

    This resource has 10000+ mentions.

http://www.uniprot.org/

Collection of data of protein sequence and functional information. Resource for protein sequence and annotation data. Consortium for preservation of the UniProt databases: UniProt Knowledgebase (UniProtKB), UniProt Reference Clusters (UniRef), and UniProt Archive (UniParc), UniProt Proteomes. Collaboration between European Bioinformatics Institute (EMBL-EBI), SIB Swiss Institute of Bioinformatics and Protein Information Resource. Swiss-Prot is a curated subset of UniProtKB.

Proper citation: UniProt (RRID:SCR_002380) Copy   


http://www.mitomap.org/

Database of polymorphisms and mutations of the human mitochondrial DNA. It reports published and unpublished data on human mitochondrial DNA variation. All data is curated by hand. If you would like to submit published articles to be included in mitomap, please send them the citation and a pdf.

Proper citation: MITOMAP - A human mitochondrial genome database (RRID:SCR_002996) Copy   


http://www.socialsecurity.gov/policy/docs/microdata/nbds/

Data set of extensive information on the changing circumstances of aged and disabled beneficiaries - Living, noninstitutionalized population of the continental United States from the Social Security Administration''''s Master Benefit Record who were new recipients of Social Security benefits (first payment in mid-1980 through mid-1981) or who had established entitlement to Medicare and were eligible for, but had not received, Social Security benefits as of July 1982. Based initially on a national cross-sectional survey of new beneficiaries in 1982, the original data base was expanded with information from administrative records and a second round of interviews in 1991. Variables measured in the original New Beneficiary Survey (NBS) include demographic characteristics; employment, marital, and childbearing histories; household composition; health; income and assets; program knowledge; and information about the spouses of married respondents. The 1991 New Beneficiary Follow-up (NBF) updated marital status, household composition, and the economic profile and contains additional sections on family contacts, postretirement employment, effects of widowhood and divorce, major reasons for changes in economic status, a more extensive section on health, and information on household moves and reasons for moving. Disabled-worker beneficiaries were also asked about their efforts to return to work, experiences with rehabilitation services, and knowledge of SSA work incentive provisions. The NBDS also links to administrative files of yearly covered earnings from 1951 to 1992, Medicare expenditures from 1984 to 1999, whether an SSI application has ever been made and payment status at five points in time, and dates of death as of spring 2001. For studies of health, the Medicare expenditure variables include inpatient hospital costs, outpatient hospital costs, home health care costs, and physicians'''' charges. The survey data cover functional capacity including ADLs and IADLs. For studies of work in retirement, the survey includes yearly information on extent of work, characteristics of the current or last job, and reasons for working or not working. No other data set has such detailed baseline survey data of a population immediately after retirement or disability, enhanced with subsequent measures over an extended period of time. The data are publicly available through NACDA and the Social Security Administration Website. * Dates of Study: 1982-1991 * Study Features: Longitudinal * Sample Size: ** 18,136 (NBS 1981) ** 12,677 (NBF 1991) Links: * 1982 (ICPSR): http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/08510 * 1991 (ICPSR): http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06118

Proper citation: New Beneficiary Data System (RRID:SCR_013320) Copy   


  • RRID:SCR_013139

    This resource has 10+ mentions.

http://www.census.gov/population/international/data/idb/informationGateway.php

A computerized data set of demographic, economic and social data for 227 countries of the world. Information presented includes population, health, nutrition, mortality, fertility, family planning and contraceptive use, literacy, housing, and economic activity data. Tabular data are broken down by such variables as age, sex, and urban/rural residence. Data are organized as a series of statistical tables identified by country and table number. Each record consists of the data values associated with a single row of a given table. There are 105 tables with data for 208 countries. The second file is a note file, containing text of notes associated with various tables. These notes provide information such as definitions of categories (i.e. urban/rural) and how various values were calculated. The IDB was created in the U.S. Census Bureau''s International Programs Center (IPC) to help IPC staff meet the needs of organizations that sponsor IPC research. The IDB provides quick access to specialized information, with emphasis on demographic measures, for individual countries or groups of countries. The IDB combines data from country sources (typically censuses and surveys) with IPC estimates and projections to provide information dating back as far as 1950 and as far ahead as 2050. Because the IDB is maintained as a research tool for IPC sponsor requirements, the amount of information available may vary by country. As funding and research activity permit, the IPC updates and expands the data base content. Types of data include: * Population by age and sex * Vital rates, infant mortality, and life tables * Fertility and child survivorship * Migration * Marital status * Family planning Data characteristics: * Temporal: Selected years, 1950present, projected demographic data to 2050. * Spatial: 227 countries and areas. * Resolution: National population, selected data by urban/rural * residence, selected data by age and sex. Sources of data include: * U.S. Census Bureau * International projects (e.g., the Demographic and Health Survey) * United Nations agencies Links: * ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/08490

Proper citation: International Data Base (RRID:SCR_013139) Copy   


http://www.nitrc.org/projects/stark_aging/

Behavioral and imaging data from about 120 participants aged 18-89. Data were collected as part of a grant to use high-resolution imaging and advanced behavioral tasks to understand how aging affects the hippocampus and how this is related to age-related cognitive decline. The full dataset includes traditional neuropsycholgical measures, hippocampal-specific behavioral measures, whole-brain DTI, high-resolution DTI of the medial temporal lobes, and structural MRI including segmentation of grey/white/CSF, of cortical regions and of hippocampal subfields.

Proper citation: Stark Cross-Sectional Aging (RRID:SCR_014171) Copy   


http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/03334

A dataset generated longitudinal study that aims to explain the relationship between age and changes in the sense of control over one''''s life, over two follow-up periods. The main hypotheses are (a) over a period of time, the sense of control declines by an amount that increases with age; (b) the change in sense of control reflects an underlying change in biosocial function, which accelerates with age; (c) higher social status slows the decline in the sense of control, possibly by preserving biosocial function; and (d) changes in biosocial function and in the sense of control have deviation-amplifying reciprocal effects that accelerate age-dependent changes in the sense of control. This was a three-wave panel survey with fixed 3-year intervals and repeated assessments of the same variables. Questionnaire topics focused on: physical health (subjective health; activities of daily living; height and weight; health conditions; expected personal longevity); health behavior (exercise, smoking, diet, alcohol use); use of medical services (medical insurance coverage, prescription drug use); work status (current employment status; title of current job or occupation and job description; types of work, tasks, or activities; description of work or daily activity and interactions; supervisory status; management position and level; work history); sense of controlextent of agreement or disagreement with planning and responsibility versus luck and bad breaks; sense of victimhood versus control; social support and participation; personal and household demographics; marital and family relations; socioeconomic status; history of adversity. * Dates of Study: 1994-2001 * Sample Size: 2,593 (Waves 1-2); 1.144 (Wave 3) * Study Features: Longitudinal Data Archives: http://www.sscnet.ucla.edu/issr/da/da_catalog/da_catalog_titleRecord.php?studynumber=I3334V1

Proper citation: Aging Status and Sense of Control (ASOC) (RRID:SCR_013500) Copy   


http://www.cdc.gov/nchs/lsoa.htm

A data set of a multicohort study of persons 70 years of age and over designed primarily to measure changes in the health, functional status, living arrangements, and health services utilization of two cohorts of Americans as they move into and through the oldest ages. The project is comprised of four surveys: * The 1984 Supplement on Aging (SOA) * The 1984-1990 Longitudinal Study of Aging (LSOA) * The 1994 Second Supplement on Aging (SOA II) * The 1994-2000 Second Longitudinal Study of Aging (LSOA II) The surveys, administered by the U.S. Census Bureau, provide a mechanism for monitoring the impact of proposed changes in Medicare and Medicaid and the accelerating shift toward managed care on the health status of the elderly and their patterns of health care utilization. SOA and SOA II were conducted as part of the in-person National Health Interview Survey (NHIS) of noninstitutionalized elderly people aged 55 years and over living in the United States in 1984, and at least 70 years of age in 1994, respectively. The 1984 SOA served as the baseline for the LSOA, which followed all persons who were 70 years of age and over in 1984 through three follow-up waves, conducted by telephone in 1986, 1988, and 1990. The SOA covered housing characteristics, family structure and living arrangements, relationships and social contracts, use of community services, occupation and retirement (income sources), health conditions and impairments, functional status, assistance with basic activities, utilization of health services, nursing home stays, and health opinions. Most of the questions from the SOA were repeated in the SOA II. Topics new to the SOA II included use of assistive devices and medical implants; health conditions and impairments; health behaviors; transportation; functional status, assistance with basic activities, unmet needs; utilization of health services; and nursing home stays. The major focus of the LSOA follow-up interviews was on functional status and changes that had occurred between interviews. Information was also collected on housing and living arrangements, contact with children, utilization of health services and nursing home stays, health insurance coverage, and income. LSOA II also included items on cognitive functioning, income and assets, family and childhood health, and more extensive health insurance information. The interview data are augmented by linkage to Medicare enrollment and utilization records, the National Death Index, and multiple cause-of-death records. Data Availability: Copies of the LSOA CD-ROMs are available through the NCHS or through ICPSR as Study number 8719. * Dates of Study: 1984-2000 * Study Features: Longitudinal * Sample Size: ** 1984: 16,148 (55+, SOA) ** 1984: 7,541(70+, LSOA) ** 1986: 5,151 (LSOA followup 1) ** 1988: 6,921 (LSOA followup 2) ** 1990: 5,978 (LSOA followup 3) ** 1994-6: 9,447 (LSOA II baseline) ** 1997-8: 7,998 (LSOA II wave 2) ** 1999-0: 6,465 (LSOA II wave 3) Link: * LSOA 1984-1990 ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/08719

Proper citation: Longitudinal Studies of Aging (RRID:SCR_013355) Copy   


  • RRID:SCR_000496

http://scicrunch.org/Aging

Portal devoted to aging relevant scientific data and resources.

Proper citation: Aging Portal (RRID:SCR_000496) Copy   


  • RRID:SCR_001378

    This resource has 1+ mentions.

http://www.morpholinodatabase.org/

Central database to house data on morpholino screens currently containing over 700 morpholinos including control and multiple morpholinos against the same target. A publicly accessible sequence-based search opens this database for morpholinos against a particular target for the zebrafish community. Morpholino Screens: They set out to identify all cotranslationally translocated genes in the zebrafish genome (Secretome/CTT-ome). Morpholinos were designed against putative secreted/CTT targets and injected into 1-4 cell stage zebrafish embryos. The embryos were observed over a 5 day period for defects in several different systems. The first screen examined 184 gene targets of which 26 demonstrated defects of interest (Pickart et al. 2006). A collaboration with the Verfaillie laboratory examined the knockdown of targets identified in a comparative microarray analysis of hematopoietic stem cells demonstrating how microarray and morpholino technologies can be used in conjunction to enrich for defects in specific developmental processes. Currently, many collaborations are underway to identify genes involved in morphological, kidney, skin, eye, pigment, vascular and hematopoietic development, lipid metabolism and more. The screen types referred to in the search functions are the specific areas of development that were examined during the various screens, which include behavior, general morphology, pigmentation, toxicity, Pax2 expression, and development of the craniofacial structures, eyes, kidneys, pituitary, and skin. Only data pertaining to specific tests performed are presented. Due to the complexity of this international collaboration and time constraints, not all morpholinos were subjected to all screen types. They are currently expanding public access to the database. In the future we will provide: * Mortality curves and dose range for each morpholino * Preliminary data regarding the effectiveness of each morpholino * Expanded annotation for each morpholino * External linkage of our morpholino sequences to ZFIN and Ensembl. To submit morpholino-knockdown results to MODB please contact the administrator for a user name and password.

Proper citation: Morpholino Database (RRID:SCR_001378) Copy   


  • RRID:SCR_002388

    This resource has 100+ mentions.

http://www.genenetwork.org/

Web platform that provides access to data and tools to study complex networks of genes, molecules, and higher order gene function and phenotypes. Sequence data (SNPs) and transcriptome data sets (expression genetic or eQTL data sets). Quantitative trait locus (QTL) mapping module that is built into GN is optimized for fast on-line analysis of traits that are controlled by combinations of gene variants and environmental factors. Used to study humans, mice (BXD, AXB, LXS, etc.), rats (HXB), Drosophila, and plant species (barley and Arabidopsis). Users are welcome to enter their own private data.

Proper citation: GeneNetwork (RRID:SCR_002388) Copy   


http://www.icpsr.umich.edu/

Data archive of more than 500,000 files of research in the social sciences, hosting 16 specialized collections of data in education, aging, criminal justice, substance abuse, terrorism, and other fields. ICPSR comprises a consortium of about 700 academic institutions and research organizations providing training in data access, curation, and methods of analysis for the social science research community. ICPSR welcomes and encourages deposits of digital data. ICPSR's educational activities include the Summer Program in Quantitative Methods of Social Research external link, a comprehensive curriculum of intensive courses in research design, statistics, data analysis, and social methodology. ICPSR also leads several initiatives that encourage use of data in teaching, particularly for undergraduate instruction. ICPSR-sponsored research focuses on the emerging challenges of digital curation and data science. ICPSR researchers also examine substantive issues related to our collections, with an emphasis on historical demography and the environment.

Proper citation: Inter-university Consortium for Political and Social Research (ICPSR) (RRID:SCR_003194) Copy   


  • RRID:SCR_003212

    This resource has 100+ mentions.

http://phenome.jax.org/

Database enables integration of genomic and phenomic data by providing access to primary experimental data, data collection protocols and analysis tools. Data represent behavioral, morphological and physiological disease-related characteristics in naive mice and those exposed to drugs, environmental agents or other treatments. Collaborative standardized collection of measured data on laboratory mouse strains to characterize them in order to facilitate translational discoveries and to assist in selection of strains for experimental studies. Includes baseline phenotype data sets as well as studies of drug, diet, disease and aging effect., protocols, projects and publications, and SNP, variation and gene expression studies. Provides tools for online analysis. Data sets are voluntarily contributed by researchers from variety of institutions and settings, or retrieved by MPD staff from open public sources. MPD has three major types of strain-centric data sets: phenotype strain surveys, SNP and variation data, and gene expression strain surveys. MPD collects data on classical inbred strains as well as any fixed-genotype strains and derivatives that are openly acquirable by the research community. New panels include Collaborative Cross (CC) lines and Diversity Outbred (DO) populations. Phenotype data include measurements of behavior, hematology, bone mineral density, cholesterol levels, endocrine function, aging processes, addiction, neurosensory functions, and other biomedically relevant areas. Genotype data are primarily in the form of single-nucleotide polymorphisms (SNPs). MPD curates data into a common framework by standardizing mouse strain nomenclature, standardizing units (SI where feasible), evaluating data (completeness, statistical power, quality), categorizing phenotype data and linking to ontologies, conforming to internal style guides for titles, tags, and descriptions, and creating comprehensive protocol documentation including environmental parameters of the test animals. These elements are critical for experimental reproducibility.

Proper citation: Mouse Phenome Database (MPD) (RRID:SCR_003212) Copy   



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